12921


Mus musculus (NCBI)
receptorregulationsignalingresponsepathwayg-proteincoupledactivitycellbindingbehavioralhormonemembraneadenylatebehaviorsecretioncorticotropin-releasingcalciumfeedingsynapticstimulusneuronbodyplasmacomponentpeptidehypoxiasignaltransductionsurface

Features
Gene ID: 12921
  
Biological name :
  
Synonyms : corticotropin releasing hormone receptor 1 / CRF1R|CRFR1|Crhr / Crhr1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418810_at (Mouse Genome 430 2.0 Array)   1427782_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039735553
RefSeq - 1039735555
RefSeq - 6681013
RefSeq - 927231744
RefSeq - 927231746
RefSeq - NC_000077.6
RefSeq - NP_001300857.1
RefSeq - NP_001300858.1
RefSeq - NP_031788.1
RefSeq - XP_017169735.1
RefSeq - XP_017169736.1
RefSeq - XR_001779869.1
RefSeq - XM_017314246.1
RefSeq - XM_017314247.1
RefSeq - NM_001313928.1
RefSeq - NM_001313929.1
RefSeq - NM_007762.5
RefSeq - XR_001779870.1
RefSeq - XR_001779871.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000018634 to get all the annotations available for this gene.


Gene Ontology (GO)
response to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponse to stressresponse to abiotic stimuluscell communicationcellular response to stimulusregulation of biological qualitysystem processfeeding behaviorregulation of molecular functionanatomical structure developmentcellular developmental processestablishment of localizationlocomotory behaviorexploration behaviorimmune responsecellular localizationcell activationimmune effector processresponse to chemicaladult behaviorresponse to endogenous stimuluscell deathmacromolecule localizationresponresponse to stressresponresponse to abiotic stimuluscell ccell communicationcellulcellular response to stimulusregularegulation of biological qualitysystemsystem processfeedinfeeding behaviorregularegulation of molecular functionanatomanatomical structure developmentcellulcellular developmental processestablestablishment of localizationlocomolocomotory behaviorexplorexploration behaviorimmuneimmune responsecellulcellular localizationcell acell activationimmuneimmune effector processresponresponse to chemicaladult adult behaviorresponresponse to endogenous stimuluscell dcell deathmacrommacromolecule localization
protein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingsignaling receptor activityhormone bindingamide bindingprotein-containing complex bindingneurotransmitter bindingprotein bindingprotein bindingsignaling receptor actisignaling receptor activityhormone bindinghormone bindingamide bindingamide bindingprotein-containing compprotein-containing complex bindingneurotransmitter bindinneurotransmitter binding
cellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellorganellemembranecellcellorganelleorganellemembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007166 cell surface receptor signaling pathway IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IEA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007218 neuropeptide signaling pathway ISO
 biological_processGO:0007613 memory ISO
 biological_processGO:0007631 feeding behavior ISO
 biological_processGO:0008542 visual learning ISO
 biological_processGO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway ISO
 biological_processGO:0030325 adrenal gland development IMP
 biological_processGO:0030855 epithelial cell differentiation ISO
 biological_processGO:0032811 negative regulation of epinephrine secretion ISO
 biological_processGO:0035641 locomotory exploration behavior ISO
 biological_processGO:0042596 fear response IMP
 biological_processGO:0043306 positive regulation of mast cell degranulation ISO
 biological_processGO:0043950 positive regulation of cAMP-mediated signaling ISO
 biological_processGO:0048148 behavioral response to cocaine ISO
 biological_processGO:0048149 behavioral response to ethanol IMP
 biological_processGO:0048167 regulation of synaptic plasticity ISO
 biological_processGO:0048266 behavioral response to pain ISO
 biological_processGO:0051458 corticotropin secretion IMP
 biological_processGO:0051602 response to electrical stimulus ISO
 biological_processGO:0051867 general adaptation syndrome, behavioral process IMP
 biological_processGO:0060291 long-term synaptic potentiation ISO
 biological_processGO:0071376 cellular response to corticotropin-releasing hormone stimulus ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity ISO
 biological_processGO:2000252 negative regulation of feeding behavior ISO
 biological_processGO:2000852 regulation of corticosterone secretion IMP
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005771 multivesicular body ISO
 cellular_componentGO:0005802 trans-Golgi network ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0031226 intrinsic component of plasma membrane ISO
 cellular_componentGO:0031982 vesicle ISO
 cellular_componentGO:0043005 neuron projection IBA
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0045177 apical part of cell ISO
 molecular_functionGO:0001965 G-protein alpha-subunit binding ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IEA
 molecular_functionGO:0004930 G-protein coupled receptor activity ISO
 molecular_functionGO:0015056 corticotrophin-releasing factor receptor activity ISO
 molecular_functionGO:0017046 peptide hormone binding IBA
 molecular_functionGO:0042277 peptide binding ISO
 molecular_functionGO:0043404 corticotropin-releasing hormone receptor activity ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0051424 corticotropin-releasing hormone binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr