13489


Mus musculus (NCBI)

Features
Gene ID: 13489
  
Biological name :
  
Synonyms : D2R|Drd-2 / dopamine receptor D2 / Drd2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418950_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 568958819
RefSeq - XP_006510059.1
RefSeq - NC_000075.6
RefSeq - 148747212
RefSeq - NP_034207.2
RefSeq - NM_010077.2
RefSeq - XM_006509996.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000032259 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001659 temperature homeostasis IMP
 biological_processGO:0001666 response to hypoxia ISO
 biological_processGO:0001933 negative regulation of protein phosphorylation ISO
 biological_processGO:0001963 synaptic transmission, dopaminergic ISO
 biological_processGO:0001964 startle response IMP
 biological_processGO:0001975 response to amphetamine IMP
 biological_processGO:0001976 neurological system process involved in regulation of systemic arterial blood pressure IMP
 biological_processGO:0002027 regulation of heart rate IMP
 biological_processGO:0002028 regulation of sodium ion transport IMP
 biological_processGO:0002031 G-protein coupled receptor internalization ISO
 biological_processGO:0002052 positive regulation of neuroblast proliferation IDA
 biological_processGO:0002092 positive regulation of receptor internalization ISO
 biological_processGO:0006914 autophagy ISO
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007186 G-protein coupled receptor signaling pathway IDA
 biological_processGO:0007188 adenylate cyclase-modulating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007194 negative regulation of adenylate cyclase activity ISO
 biological_processGO:0007195 adenylate cyclase-inhibiting dopamine receptor signaling pathway ISO
 biological_processGO:0007212 dopamine receptor signaling pathway ISO
 biological_processGO:0007267 cell-cell signaling IBA
 biological_processGO:0007270 neuron-neuron synaptic transmission IMP
 biological_processGO:0007409 axonogenesis IMP
 biological_processGO:0007608 sensory perception of smell IMP
 biological_processGO:0007616 long-term memory ISO
 biological_processGO:0007625 grooming behavior IMP
 biological_processGO:0007626 locomotory behavior ISO
 biological_processGO:0007628 adult walking behavior IMP
 biological_processGO:0007631 feeding behavior IGI
 biological_processGO:0008104 protein localization IMP
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0008306 associative learning IMP
 biological_processGO:0008542 visual learning IMP
 biological_processGO:0009416 response to light stimulus IMP
 biological_processGO:0014059 regulation of dopamine secretion IMP
 biological_processGO:0016055 Wnt signaling pathway ISO
 biological_processGO:0021853 cerebral cortex GABAergic interneuron migration IMP
 biological_processGO:0021984 adenohypophysis development IMP
 biological_processGO:0030336 negative regulation of cell migration IMP
 biological_processGO:0030432 peristalsis IMP
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0030900 forebrain development ISO
 biological_processGO:0031223 auditory behavior ISO
 biological_processGO:0032147 activation of protein kinase activity ISO
 biological_processGO:0032228 regulation of synaptic transmission, GABAergic IMP
 biological_processGO:0032467 positive regulation of cytokinesis ISO
 biological_processGO:0032922 circadian regulation of gene expression IMP
 biological_processGO:0033602 negative regulation of dopamine secretion ISO
 biological_processGO:0034776 response to histamine ISO
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0035810 positive regulation of urine volume IMP
 biological_processGO:0035815 positive regulation of renal sodium excretion IMP
 biological_processGO:0040018 positive regulation of multicellular organism growth IMP
 biological_processGO:0042220 response to cocaine IMP
 biological_processGO:0042321 negative regulation of circadian sleep/wake cycle, sleep ISO
 biological_processGO:0042417 dopamine metabolic process IMP
 biological_processGO:0042493 response to drug ISO
 biological_processGO:0042756 drinking behavior ISO
 biological_processGO:0043266 regulation of potassium ion transport ISO
 biological_processGO:0043278 response to morphine IMP
 biological_processGO:0043408 regulation of MAPK cascade ISO
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0043666 regulation of phosphoprotein phosphatase activity ISO
 biological_processGO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway ISO
 biological_processGO:0045776 negative regulation of blood pressure IMP
 biological_processGO:0045824 negative regulation of innate immune response IMP
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046676 negative regulation of insulin secretion ISO
 biological_processGO:0046717 acid secretion ISO
 biological_processGO:0048148 behavioral response to cocaine IMP
 biological_processGO:0048149 behavioral response to ethanol IMP
 biological_processGO:0048169 regulation of long-term neuronal synaptic plasticity IMP
 biological_processGO:0048755 branching morphogenesis of a nerve IMP
 biological_processGO:0050482 arachidonic acid secretion ISO
 biological_processGO:0050709 negative regulation of protein secretion ISO
 biological_processGO:0050769 positive regulation of neurogenesis ISO
 biological_processGO:0050804 modulation of chemical synaptic transmission ISO
 biological_processGO:0051209 release of sequestered calcium ion into cytosol ISO
 biological_processGO:0051481 negative regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway ISO
 biological_processGO:0051584 regulation of dopamine uptake involved in synaptic transmission IMP
 biological_processGO:0051586 positive regulation of dopamine uptake involved in synaptic transmission IMP
 biological_processGO:0051823 regulation of synapse structural plasticity ISO
 biological_processGO:0051898 negative regulation of protein kinase B signaling IMP
 biological_processGO:0051967 negative regulation of synaptic transmission, glutamatergic IMP
 biological_processGO:0060124 positive regulation of growth hormone secretion IMP
 biological_processGO:0060134 prepulse inhibition IMP
 biological_processGO:0060158 phospholipase C-activating dopamine receptor signaling pathway ISO
 biological_processGO:0060160 negative regulation of dopamine receptor signaling pathway IMP
 biological_processGO:0060548 negative regulation of cell death ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway IBA
 biological_processGO:0090325 regulation of locomotion involved in locomotory behavior ISO
 biological_processGO:1900168 positive regulation of glial cell-derived neurotrophic factor secretion ISO
 biological_processGO:1900273 positive regulation of long-term synaptic potentiation ISO
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity ISO
 cellular_componentGO:0001669 acrosomal vesicle ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016328 lateral plasma membrane ISO
 cellular_componentGO:0030139 endocytic vesicle ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0030672 synaptic vesicle membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle ISO
 cellular_componentGO:0036126 sperm flagellum ISO
 cellular_componentGO:0043197 dendritic spine ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0043679 axon terminus ISO
 cellular_componentGO:0060170 ciliary membrane ISO
 cellular_componentGO:0097730 non-motile cilium ISO
 molecular_functionGO:0001591 dopamine neurotransmitter receptor activity, coupled via Gi/Go ISO
 molecular_functionGO:0004930 G-protein coupled receptor activity IDA
 molecular_functionGO:0004935 adrenergic receptor activity IBA
 molecular_functionGO:0004952 dopamine neurotransmitter receptor activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0008144 drug binding ISO
 molecular_functionGO:0035240 dopamine binding ISO
 molecular_functionGO:0035255 ionotropic glutamate receptor binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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