13649


Mus musculus (NCBI)

Features
Gene ID: 13649
  
Biological name :
  
Synonyms : 9030024J15Rik|AI552599|Erbb|Errb1|Errp|Wa5|wa-2|wa2 / Egfr / epidermal growth factor receptor
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1424932_at (Mouse Genome 430 2.0 Array)   1432647_at (Mouse Genome 430 2.0 Array)   1435888_at (Mouse Genome 430 2.0 Array)   1451530_at (Mouse Genome 430 2.0 Array)   1454313_at (Mouse Genome 430 2.0 Array)   1457563_at (Mouse Genome 430 2.0 Array)   1460420_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - NP_031938.1
RefSeq - NP_997538.1
RefSeq - NC_000077.6
RefSeq - 46560582
RefSeq - 6681283
RefSeq - NM_007912.4
RefSeq - NM_207655.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000020122 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000186 activation of MAPKK activity ISO
 biological_processGO:0000902 cell morphogenesis IGI
 biological_processGO:0001892 embryonic placenta development IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0001942 hair follicle development IMP
 biological_processGO:0006412 translation ISO
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006898 receptor-mediated endocytosis ISO
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0007166 cell surface receptor signaling pathway ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007435 salivary gland morphogenesis IMP
 biological_processGO:0007611 learning or memory ISO
 biological_processGO:0008283 cell proliferation ISO
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008544 epidermis development IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010750 positive regulation of nitric oxide mediated signal transduction ISO
 biological_processGO:0010960 magnesium ion homeostasis ISO
 biological_processGO:0014066 regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0021795 cerebral cortex cell migration IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle ISO
 biological_processGO:0032930 positive regulation of superoxide anion generation ISO
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0035556 intracellular signal transduction ISO
 biological_processGO:0038083 peptidyl-tyrosine autophosphorylation ISO
 biological_processGO:0042060 wound healing ISO
 biological_processGO:0042127 regulation of cell proliferation IGI
 biological_processGO:0042177 negative regulation of protein catabolic process ISO
 biological_processGO:0042327 positive regulation of phosphorylation ISO
 biological_processGO:0042698 ovulation cycle ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043406 positive regulation of MAP kinase activity ISO
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045739 positive regulation of DNA repair ISO
 biological_processGO:0045740 positive regulation of DNA replication ISO
 biological_processGO:0045780 positive regulation of bone resorption ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045907 positive regulation of vasoconstriction ISO
 biological_processGO:0045930 negative regulation of mitotic cell cycle ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046328 regulation of JNK cascade ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048143 astrocyte activation ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation IMP
 biological_processGO:0048546 digestive tract morphogenesis IMP
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048812 neuron projection morphogenesis ISO
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISO
 biological_processGO:0050729 positive regulation of inflammatory response ISO
 biological_processGO:0050730 regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050999 regulation of nitric-oxide synthase activity ISO
 biological_processGO:0051592 response to calcium ion ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling ISO
 biological_processGO:0051968 positive regulation of synaptic transmission, glutamatergic ISO
 biological_processGO:0060571 morphogenesis of an epithelial fold IMP
 biological_processGO:0061029 eyelid development in camera-type eye IGI
 biological_processGO:0070141 response to UV-A ISO
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 biological_processGO:0071276 cellular response to cadmium ion ISO
 biological_processGO:0071363 cellular response to growth factor stimulus IDA
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus ISO
 biological_processGO:0071392 cellular response to estradiol stimulus ISO
 biological_processGO:0090263 positive regulation of canonical Wnt signaling pathway ISO
 biological_processGO:0097755 positive regulation of blood vessel diameter ISO
 biological_processGO:0098609 cell-cell adhesion ISO
 biological_processGO:1900020 positive regulation of protein kinase C activity ISO
 biological_processGO:1901224 positive regulation of NIK/NF-kappaB signaling ISO
 biological_processGO:1902722 positive regulation of prolactin secretion ISO
 biological_processGO:1903078 positive regulation of protein localization to plasma membrane ISO
 biological_processGO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA ISO
 biological_processGO:1905208 negative regulation of cardiocyte differentiation ISO
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005768 endosome ISO
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009925 basal plasma membrane IBA
 cellular_componentGO:0009986 cell surface ISO
 cellular_componentGO:0010008 endosome membrane ISO
 cellular_componentGO:0016020 membrane ISO
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0030139 endocytic vesicle ISO
 cellular_componentGO:0031901 early endosome membrane ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045202 synapse ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 cellular_componentGO:0097489 multivesicular body, internal vesicle lumen ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0003682 chromatin binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity ISO
 molecular_functionGO:0005006 epidermal growth factor-activated receptor activity ISO
 molecular_functionGO:0005102 signaling receptor binding ISO
 molecular_functionGO:0005178 integrin binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005516 calmodulin binding ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IDA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0030235 nitric-oxide synthase regulator activity ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0048408 epidermal growth factor binding ISO
 molecular_functionGO:0051015 actin filament binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr