13866


Mus musculus (NCBI)

Features
Gene ID: 13866
  
Biological name :
  
Synonyms : Erbb2 / Erbb-2|HER-2|HER2|Neu|c-erbB2|c-neu|l11Jus8|mKIAA3023 / erb-b2 receptor tyrosine kinase 2
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1424919_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 54873610
RefSeq - NC_000077.6
RefSeq - NP_001003817.1
RefSeq - NM_001003817.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000062312 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007165 signal transduction ISO
 biological_processGO:0007166 cell surface receptor signaling pathway ISO
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway ISO
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007399 nervous system development IMP
 biological_processGO:0007422 peripheral nervous system development ISO
 biological_processGO:0007507 heart development IMP
 biological_processGO:0007528 neuromuscular junction development IMP
 biological_processGO:0008045 motor neuron axon guidance IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010001 glial cell differentiation ISO
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0014065 phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0032886 regulation of microtubule-based process ISO
 biological_processGO:0033088 negative regulation of immature T cell proliferation in thymus IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0042060 wound healing ISO
 biological_processGO:0042552 myelination IMP
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043406 positive regulation of MAP kinase activity ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043547 positive regulation of GTPase activity IMP
 biological_processGO:0044849 estrous cycle ISO
 biological_processGO:0045727 positive regulation of translation ISO
 biological_processGO:0045785 positive regulation of cell adhesion ISO
 biological_processGO:0045943 positive regulation of transcription by RNA polymerase I ISO
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III ISO
 biological_processGO:0046579 positive regulation of Ras protein signal transduction ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048485 sympathetic nervous system development ISO
 biological_processGO:0048678 response to axon injury ISO
 biological_processGO:0048709 oligodendrocyte differentiation IMP
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISO
 biological_processGO:0070372 regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071363 cellular response to growth factor stimulus ISO
 biological_processGO:0071364 cellular response to epidermal growth factor stimulus ISO
 biological_processGO:0090314 positive regulation of protein targeting to membrane ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005902 microvillus ISO
 cellular_componentGO:0009925 basal plasma membrane ISO
 cellular_componentGO:0010008 endosome membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane NAS
 cellular_componentGO:0016323 basolateral plasma membrane ISO
 cellular_componentGO:0016324 apical plasma membrane ISO
 cellular_componentGO:0031410 cytoplasmic vesicle IDA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0043219 lateral loop ISO
 cellular_componentGO:0043235 receptor complex ISO
 cellular_componentGO:0045121 membrane raft ISO
 cellular_componentGO:0045211 postsynaptic membrane ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0001042 RNA polymerase I core binding ISO
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008022 protein C-terminus binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0051879 Hsp90 protein binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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