13982


Mus musculus (NCBI)

Features
Gene ID: 13982
  
Biological name :
  
Synonyms : ER|ER-alpha|ERa|ERalpha|ESR|Estr|Estra|Nr3a1 / Esr1 / estrogen receptor 1 (alpha)
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421244_at (Mouse Genome 430 2.0 Array)   1435663_at (Mouse Genome 430 2.0 Array)   1460591_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_017169286.1
RefSeq - 568964650
RefSeq - 568964652
RefSeq - 568964654
RefSeq - 6679695
RefSeq - 700274121
RefSeq - 700274123
RefSeq - 700274125
RefSeq - 755532636
RefSeq - 755532638
RefSeq - 755532641
RefSeq - NC_000076.6
RefSeq - NP_001289460.1
RefSeq - NP_001289461.1
RefSeq - NP_001289462.1
RefSeq - NP_031982.1
RefSeq - XP_006512496.1
RefSeq - XP_006512497.1
RefSeq - XP_006512498.1
RefSeq - XP_011241368.1
RefSeq - XP_011241369.1
RefSeq - XP_011241370.1
RefSeq - 1039732094
RefSeq - XM_006512435.2
RefSeq - NM_001302531.1
RefSeq - NM_001302532.1
RefSeq - NM_001302533.1
RefSeq - NM_007956.5
RefSeq - XM_011243066.2
RefSeq - XM_011243067.2
RefSeq - XM_011243068.2
RefSeq - XM_017313797.1
RefSeq - NR_126357.1
RefSeq - XM_006512433.3
RefSeq - XM_006512434.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000019768 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISO
 biological_processGO:0001547 antral ovarian follicle growth IMP
 biological_processGO:0002064 epithelial cell development IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006366 transcription by RNA polymerase II ISO
 biological_processGO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway ISO
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0008209 androgen metabolic process IMP
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010863 positive regulation of phospholipase C activity ISO
 biological_processGO:0030518 intracellular steroid hormone receptor signaling pathway ISO
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway ISO
 biological_processGO:0032355 response to estradiol ISO
 biological_processGO:0034121 regulation of toll-like receptor signaling pathway IMP
 biological_processGO:0042981 regulation of apoptotic process IMP
 biological_processGO:0043124 negative regulation of I-kappaB kinase/NF-kappaB signaling ISO
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043433 negative regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0043523 regulation of neuron apoptotic process ISO
 biological_processGO:0043627 response to estrogen ISO
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISO
 biological_processGO:0045742 positive regulation of epidermal growth factor receptor signaling pathway ISO
 biological_processGO:0045839 negative regulation of mitotic nuclear division NAS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly ISO
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISO
 biological_processGO:0046325 negative regulation of glucose import ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation IMP
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation ISO
 biological_processGO:0048863 stem cell differentiation IDA
 biological_processGO:0050679 positive regulation of epithelial cell proliferation ISO
 biological_processGO:0050727 regulation of inflammatory response IMP
 biological_processGO:0051000 positive regulation of nitric-oxide synthase activity ISO
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0060011 Sertoli cell proliferation ISO
 biological_processGO:0060065 uterus development IGI
 biological_processGO:0060068 vagina development IGI
 biological_processGO:0060523 prostate epithelial cord elongation IMP
 biological_processGO:0060527 prostate epithelial cord arborization involved in prostate glandular acinus morphogenesis IMP
 biological_processGO:0060687 regulation of branching involved in prostate gland morphogenesis IMP
 biological_processGO:0060745 mammary gland branching involved in pregnancy IMP
 biological_processGO:0060749 mammary gland alveolus development IMP
 biological_processGO:0060750 epithelial cell proliferation involved in mammary gland duct elongation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071168 protein localization to chromatin ISO
 biological_processGO:0071391 cellular response to estrogen stimulus IMP
 biological_processGO:0071392 cellular response to estradiol stimulus ISO
 biological_processGO:0090209 negative regulation of triglyceride metabolic process ISO
 biological_processGO:1901215 negative regulation of neuron death ISO
 biological_processGO:1903799 negative regulation of production of miRNAs involved in gene silencing by miRNA ISO
 cellular_componentGO:0000790 nuclear chromatin ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005739 mitochondrion ISO
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030315 T-tubule ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0035327 transcriptionally active chromatin ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043195 terminal bouton ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0097550 transcriptional preinitiation complex ISO
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding ISO
 molecular_functionGO:0001093 TFIIB-class transcription factor binding ISO
 molecular_functionGO:0001223 transcription coactivator binding ISO
 molecular_functionGO:0003677 DNA binding ISO
 molecular_functionGO:0003682 chromatin binding ISO
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity ISO
 molecular_functionGO:0004879 nuclear receptor activity IDA
 molecular_functionGO:0005496 steroid binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding ISO
 molecular_functionGO:0008134 transcription factor binding ISO
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0017025 TBP-class protein binding ISO
 molecular_functionGO:0019899 enzyme binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0030284 estrogen receptor activity ISO
 molecular_functionGO:0030331 estrogen receptor binding ISO
 molecular_functionGO:0031798 type 1 metabotropic glutamate receptor binding ISO
 molecular_functionGO:0034056 estrogen response element binding ISO
 molecular_functionGO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding ISO
 molecular_functionGO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding ISO
 molecular_functionGO:0042562 hormone binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044877 protein-containing complex binding ISO
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding ISO
 molecular_functionGO:1990841 promoter-specific chromatin binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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