14179


Mus musculus (NCBI)
developmentmorphogenesisregulationcellinvolvedgrowthneuronfactordifferentiationheartfibroblastreceptorforebrainbranchingformationapoptoticprocessmigrationsignalingpathwaybindingcascadebloodvesselorganoutflowtractaxonguidanceproliferation

Features
Gene ID: 14179
  
Biological name :
  
Synonyms : Aigf|Fgf-8 / Fgf8 / fibroblast growth factor 8
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1451882_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 22094093
RefSeq - 261599074
RefSeq - 261599076
RefSeq - 261599078
RefSeq - 569006378
RefSeq - 755562775
RefSeq - 755562777
RefSeq - NC_000085.6
RefSeq - NP_001159833.1
RefSeq - NP_001159834.1
RefSeq - NP_001159835.1
RefSeq - NP_034335.1
RefSeq - XP_006526731.1
RefSeq - XP_011245444.1
RefSeq - XP_011245445.1
RefSeq - NM_001166361.1
RefSeq - NM_001166362.1
RefSeq - NM_001166363.1
RefSeq - NM_010205.2
RefSeq - XM_011247143.1
RefSeq - XM_006526668.3
RefSeq - XM_011247142.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000025219 to get all the annotations available for this gene.


Gene Ontology (GO)
nitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitrogen compound metabolic processcell communicationcellular metabolic processprimary metabolic processorganic substance metabolic processcellular response to stimulusanatomical structure developmentdevelopmental inductiontissue remodelingcellular developmental processcell deathresponse to stressresponse to external stimuluscellular component organizationresponse to chemicalmovement of cell or subcellular componentlocalization of cellresponse to endogenous stimulusneural precursor cell proliferationbiosynthetic processcell cycledevelopmental growthcell divisiontissue migrationnitronitrogen compound metabolic processcell cell communicationcellucellular metabolic processprimaprimary metabolic processorganorganic substance metabolic processcellucellular response to stimulusanatoanatomical structure developmentdeveldevelopmental inductiontissutissue remodelingcellucellular developmental processcell cell deathresporesponse to stressresporesponse to external stimuluscellucellular component organizationresporesponse to chemicalmovemmovement of cell or subcellular componentlocallocalization of cellresporesponse to endogenous stimulusneuraneural precursor cell proliferationbiosybiosynthetic processcell cell cycledeveldevelopmental growthcell cell divisiontissutissue migration
protein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingreceptor regulator activityprotein bindingprotein bindingreceptor regulator activityreceptor regulator activity
extracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regioncellmembraneextracellular regionextracellular regioncellcellmembranemembrane
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade IMP
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IGI
 biological_processGO:0001658 branching involved in ureteric bud morphogenesis IMP
 biological_processGO:0001759 organ induction IGI
 biological_processGO:0001822 kidney development IMP
 biological_processGO:0001839 neural plate morphogenesis IMP
 biological_processGO:0001947 heart looping IMP
 biological_processGO:0001974 blood vessel remodeling IGI
 biological_processGO:0003007 heart morphogenesis IMP
 biological_processGO:0003148 outflow tract septum morphogenesis IGI
 biological_processGO:0003151 outflow tract morphogenesis IGI
 biological_processGO:0003198 epithelial to mesenchymal transition involved in endocardial cushion formation IMP
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0006979 response to oxidative stress ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0007368 determination of left/right symmetry IMP
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008045 motor neuron axon guidance ISO
 biological_processGO:0008078 mesodermal cell migration IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008406 gonad development ISO
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway ISO
 biological_processGO:0009792 embryo development ending in birth or egg hatching IMP
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0021537 telencephalon development IMP
 biological_processGO:0021543 pallium development IMP
 biological_processGO:0021544 subpallium development IMP
 biological_processGO:0021798 forebrain dorsal/ventral pattern formation IMP
 biological_processGO:0021846 cell proliferation in forebrain IMP
 biological_processGO:0021884 forebrain neuron development ISO
 biological_processGO:0021954 central nervous system neuron development ISO
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030509 BMP signaling pathway IDA
 biological_processGO:0030539 male genitalia development IDA
 biological_processGO:0030878 thyroid gland development IMP
 biological_processGO:0030916 otic vesicle formation TAS
 biological_processGO:0030917 midbrain-hindbrain boundary development IMP
 biological_processGO:0033563 dorsal/ventral axon guidance ISO
 biological_processGO:0035050 embryonic heart tube development IMP
 biological_processGO:0035108 limb morphogenesis IGI
 biological_processGO:0035116 embryonic hindlimb morphogenesis IGI
 biological_processGO:0035909 aorta morphogenesis IGI
 biological_processGO:0042472 inner ear morphogenesis IGI
 biological_processGO:0042487 regulation of odontogenesis of dentin-containing tooth IGI
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0045165 cell fate commitment IGI
 biological_processGO:0045840 positive regulation of mitotic nuclear division IDA
 biological_processGO:0046622 positive regulation of organ growth IMP
 biological_processGO:0048699 generation of neurons IMP
 biological_processGO:0048853 forebrain morphogenesis IMP
 biological_processGO:0051781 positive regulation of cell division IEA
 biological_processGO:0055026 negative regulation of cardiac muscle tissue development ISO
 biological_processGO:0060037 pharyngeal system development IGI
 biological_processGO:0060070 canonical Wnt signaling pathway IDA
 biological_processGO:0060128 corticotropin hormone secreting cell differentiation IDA
 biological_processGO:0060129 thyroid-stimulating hormone-secreting cell differentiation IDA
 biological_processGO:0060348 bone development ISO
 biological_processGO:0060425 lung morphogenesis IMP
 biological_processGO:0060445 branching involved in salivary gland morphogenesis IMP
 biological_processGO:0060563 neuroepithelial cell differentiation ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IGI
 biological_processGO:0071542 dopaminergic neuron differentiation TAS
 biological_processGO:0090134 cell migration involved in mesendoderm migration IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0009897 external side of plasma membrane ISO
 molecular_functionGO:0005104 fibroblast growth factor receptor binding IEA
 molecular_functionGO:0005105 type 1 fibroblast growth factor receptor binding ISO
 molecular_functionGO:0005111 type 2 fibroblast growth factor receptor binding ISO
 molecular_functionGO:0008083 growth factor activity ISO
 molecular_functionGO:0042056 chemoattractant activity ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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