14186


Mus musculus (NCBI)
regulationkinaseactivityproteinprocessbindingreceptordevelopmentfibroblastgrowthmembranephosphorylationcellfactormetabolichomeostasissignalinggeneexpressionphosphatetransportcascadeerkbiosyntheticplasmaintegralcomponenttyrosinetransmembraneangiogenesis

Features
Gene ID: 14186
  
Biological name :
  
Synonyms : Fgfr4 / fibroblast growth factor receptor 4
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1418596_at (Mouse Genome 430 2.0 Array)   1427776_a_at (Mouse Genome 430 2.0 Array)   1427777_x_at (Mouse Genome 430 2.0 Array)   1427845_at (Mouse Genome 430 2.0 Array)   1427846_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006517163.1
RefSeq - 112293260
RefSeq - 568983044
RefSeq - NC_000079.6
RefSeq - NP_032037.2
RefSeq - XP_006517162.2
RefSeq - 1039743142
RefSeq - NM_008011.2
RefSeq - XM_006517100.1
RefSeq - XM_006517099.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000005320 to get all the annotations available for this gene.


Gene Ontology (GO)
anatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomical structure developmentdevelopmental inductionnitrogen compound metabolic processcellular metabolic processprimary metabolic processorganic substance metabolic processcell communicationresponse to endogenous stimulusresponse to chemicalcellular response to stimuluscellular component organizationestablishment of localizationlocalization of cellmovement of cell or subcellular componentcellular developmental processregulation of molecular functionregulation of biological qualitycell deathsmall molecule metabolic processbiosynthetic processcytokine productionsystem processanatomanatomical structure developmentdevelodevelopmental inductionnitrognitrogen compound metabolic processcellulcellular metabolic processprimarprimary metabolic processorganiorganic substance metabolic processcell ccell communicationresponresponse to endogenous stimulusresponresponse to chemicalcellulcellular response to stimuluscellulcellular component organizationestablestablishment of localizationlocalilocalization of cellmovememovement of cell or subcellular componentcellulcellular developmental processregularegulation of molecular functionregularegulation of biological qualitycell dcell deathsmall small molecule metabolic processbiosynbiosynthetic processcytokicytokine productionsystemsystem process
organic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclic compound bindingheterocyclic compound bindingsmall molecule bindingcatalytic activity, acting on a proteintransferase activitysignaling receptor activityprotein bindingion bindingcarbohydrate derivative bindingdrug bindingsulfur compound bindingorganic cyclorganic cyclic compound bindingheterocyclicheterocyclic compound bindingsmall molecusmall molecule bindingcatalytic accatalytic activity, acting on a proteintransferase transferase activitysignaling resignaling receptor activityprotein bindprotein bindingion bindingion bindingcarbohydratecarbohydrate derivative bindingdrug bindingdrug bindingsulfur composulfur compound binding
cellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellorganellemembranecell junctionprotein-containing complexcellcellorganelleorganellemembranemembranecell junctioncell junctionprotein-containing complexprotein-containing complex
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis IBA
 biological_processGO:0001759 organ induction IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007417 central nervous system development IBA
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway ISO
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression IGI
 biological_processGO:0010715 regulation of extracellular matrix disassembly ISO
 biological_processGO:0010966 regulation of phosphate transport IGI
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0019216 regulation of lipid metabolic process IMP
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030324 lung development IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0042593 glucose homeostasis IMP
 biological_processGO:0042632 cholesterol homeostasis IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043085 positive regulation of catalytic activity ISO
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045862 positive regulation of proteolysis ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0051174 regulation of phosphorus metabolic process IGI
 biological_processGO:0055062 phosphate ion homeostasis IMP
 biological_processGO:0061144 alveolar secondary septum development IGI
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070640 vitamin D3 metabolic process IGI
 biological_processGO:0070857 regulation of bile acid biosynthetic process ISO
 biological_processGO:0090272 negative regulation of fibroblast growth factor production IGI
 biological_processGO:2000573 positive regulation of DNA biosynthetic process ISO
 biological_processGO:2000830 positive regulation of parathyroid hormone secretion IGI
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005794 Golgi apparatus ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005911 cell-cell junction ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle ISO
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008201 heparin binding ISO
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017134 fibroblast growth factor binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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