14254


Mus musculus (NCBI)

Features
Gene ID: 14254
  
Biological name :
  
Synonyms : AI323757|Flt-1|VEGFR-1|VEGFR1|sFlt1 / Flt1 / FMS-like tyrosine kinase 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419300_at (Mouse Genome 430 2.0 Array)   1440926_at (Mouse Genome 430 2.0 Array)   1451756_at (Mouse Genome 430 2.0 Array)   1454037_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_011239302.1
RefSeq - 34328180
RefSeq - 568938949
RefSeq - 568938951
RefSeq - 568938953
RefSeq - 755514961
RefSeq - NC_000071.6
RefSeq - NP_001350064.1
RefSeq - NP_034358.2
RefSeq - XP_006504864.1
RefSeq - XP_006504865.1
RefSeq - XP_006504866.1
RefSeq - 1387845411
RefSeq - NM_001363135.1
RefSeq - NM_010228.4
RefSeq - XM_006504803.3
RefSeq - XM_011241000.2
RefSeq - XM_006504801.3
RefSeq - XM_006504802.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000029648 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001525 angiogenesis TAS
 biological_processGO:0001569 branching involved in blood vessel morphogenesis IMP
 biological_processGO:0001666 response to hypoxia IMP
 biological_processGO:0002040 sprouting angiogenesis IMP
 biological_processGO:0002548 monocyte chemotaxis ISO
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010863 positive regulation of phospholipase C activity ISO
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration ISO
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus ISO
 biological_processGO:0036323 vascular endothelial growth factor receptor-1 signaling pathway ISO
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043406 positive regulation of MAP kinase activity ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0045766 positive regulation of angiogenesis ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway ISO
 biological_processGO:0048514 blood vessel morphogenesis IMP
 biological_processGO:0048597 post-embryonic camera-type eye morphogenesis IGI
 biological_processGO:0048598 embryonic morphogenesis IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:1901534 positive regulation of hematopoietic progenitor cell differentiation IMP
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation ISO
 cellular_componentGO:0005615 extracellular space IDA
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005737 cytoplasm IBA
 cellular_componentGO:0005768 endosome IEA
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0015629 actin cytoskeleton ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex ISO
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0036326 VEGF-A-activated receptor activity ISO
 molecular_functionGO:0036327 VEGF-B-activated receptor activity ISO
 molecular_functionGO:0036332 placental growth factor-activated receptor activity ISO
 molecular_functionGO:0042802 identical protein binding IPI


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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