ENSMUSG00000029648


Mus musculus

Features
Gene ID: ENSMUSG00000029648
  
Biological name :Flt1
  
Synonyms : Flt1 / fms related tyrosine kinase 1
  
Possible biological names infered from orthology : P17948
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G3
Gene start: 147561604
Gene end: 147726011
  
Corresponding Affymetrix probe sets: 10535807 (MoGene1.0st)   1419300_at (Mouse Genome 430 2.0 Array)   1440926_at (Mouse Genome 430 2.0 Array)   1451756_at (Mouse Genome 430 2.0 Array)   1454037_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000031653
Ensembl peptide - ENSMUSP00000106158
NCBI entrez gene - 14254     See in Manteia.
MGI - MGI:95558
RefSeq - XM_011241000
RefSeq - NM_010228
RefSeq - XM_006504801
RefSeq - XM_006504802
RefSeq - XM_006504803
RefSeq Peptide - NP_034358
swissprot - O55095
swissprot - A0A0R4J0A4
Ensembl - ENSMUSG00000029648
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 flt1ENSDARG00000019371Danio rerio
 FLT1ENSGALG00000017091Gallus gallus
 FLT1ENSG00000102755Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Kdr / kinase insert domain receptor / P35968*ENSMUSG0000006296043
Flt4 / P35917 / Vascular endothelial growth factor receptor 3 / P35916* / fms related tyrosine kinase 4*ENSMUSG0000002035740
P26618 / Pdgfra / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA. / P16234* / platelet derived growth factor receptor alpha*ENSMUSG0000002923124
Pdgfrb / platelet-derived growth factor receptor beta isoform 2 / P09619* / platelet derived growth factor receptor beta*ENSMUSG0000002462023
Csf1r / P09581 / Macrophage colony-stimulating factor 1 receptor / P07333* / colony stimulating factor 1 receptor*ENSMUSG0000002462122
Kit / P05532 / Mast/stem cell growth factor receptor Kit / P10721* / KIT proto-oncogene receptor tyrosine kinase*ENSMUSG0000000567222
Fgfr3 / Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 6, mRNA. / P22607* / fibroblast growth factor receptor 3*ENSMUSG0000005425219
Fgfr2 / fibroblast growth factor receptor 2 isoform 3 / P21802* / fibroblast growth factor receptor 2*ENSMUSG0000003084919
Fgfr1 / P16092 / Fibroblast growth factor receptor 1 / P11362*ENSMUSG0000003156519
Flt3 / fms related tyrosine kinase 3 / P36888*ENSMUSG0000004281719
Ret / P35546 / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment / P07949* / ret proto-oncogene*ENSMUSG0000003011018
Fgfr4 / fibroblast growth factor receptor 4 / P22455*ENSMUSG0000000532018


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR001824  Tyrosine-protein kinase, receptor class III, conserved site
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR009135  Vascular endothelial growth factor receptor 1 (VEGFR1)
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002548 monocyte chemotaxis IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0010863 positive regulation of phospholipase C activity IEA
 biological_processGO:0014068 positive regulation of phosphatidylinositol 3-kinase signaling IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0030335 positive regulation of cell migration IEA
 biological_processGO:0030949 positive regulation of vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:0035924 cellular response to vascular endothelial growth factor stimulus IEA
 biological_processGO:0036323 vascular endothelial growth factor receptor-1 signaling pathway IEA
 biological_processGO:0038084 vascular endothelial growth factor signaling pathway IEA
 biological_processGO:0043406 positive regulation of MAP kinase activity IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IEA
 biological_processGO:0045766 positive regulation of angiogenesis IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0048010 vascular endothelial growth factor receptor signaling pathway IEA
 biological_processGO:1905563 negative regulation of vascular endothelial cell proliferation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IEA
 molecular_functionGO:0036326 VEGF-A-activated receptor activity IEA
 molecular_functionGO:0036327 VEGF-B-activated receptor activity IEA
 molecular_functionGO:0036332 placental growth factor-activated receptor activity IEA


Pathways (from Reactome)
Pathway description
Neurophilin interactions with VEGF and VEGFR
VEGF binds to VEGFR leading to receptor dimerization


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000259 abnormal vascular development "malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0000267 abnormal cardiac development "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0000730 increased number of satellite cells "greater number of unfused cells in muscle that play a role in muscle regeneration" [J:42574]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0000733 abnormal muscle development "anomalous differentiation of muscle tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
Show

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Kdrtm1Jrt/Kdr+,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129 * C57BL/6NCr * CD-1

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

Allelic Composition: Flt1tm1Jrt/Flt1tm1.2Fong
Genetic Background: involves: 129 * C57BL/6NCr * CD-1

 MP:0001661 extended life span "persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0001672 abnormal embryogenesis/ development "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001700 abnormal embryo turning "atypical axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (Mus:E8.5-E9.5) such that the curvature of the entire trunk region is reversed and the neural ectoderm moves to the convex region and the midgut region becomes located in the concave region" [The Atlas of Mouse Development:ISBN 0-12-402035-6, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

 MP:0001723 disorganized vascular plexus 
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0001730 embryonic growth arrest "the cessation of development beyond a particular stage" [J:17509]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0002067 abnormal sensory capabilities/reflexes/nociception "inability or altered ability to respond to a sensory stimulus" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Xrcc6tm1Fwa/Xrcc6tm1Fwa
Genetic Background: involves: 129S6/SvEvTac

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0002128 abnormal blood circulation "failure or atypical movement in the flow of blood from the heart to the vasculature and back to the heart" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

Allelic Composition: Flt1tm1.1Vlcg/Flt1tm1.1Vlcg
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac

 MP:0003038 decreased infarction size "decreased size of necrotic area from normal of the myocardium resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
Show

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

 MP:0003070 increased vascular permeability "greater or faster ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0003224 neuron degeneration "a retrogressive impairment of function or destruction of the functional cells of the nervous system that receive, conduct, and transmit impulses " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Xrcc6tm1Fwa/Xrcc6tm1Fwa
Genetic Background: involves: 129S6/SvEvTac

 MP:0003229 abnormal vitelline vasculature "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0003543 abnormal vascular endothelial cell differentiation "anomaly in the process whereby a relatively unspecialized cell acquires specialized features of an endothelial cell" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95387]
Show

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0003544 abnormal vascular endothelial cell migration "anomaly in the movement of endothelial cell or their precursors to the appropriate location in the body" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95387]
Show

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

Allelic Composition: Flt1tm2Msh/Flt1tm2Msh,Kdrtm1Jrt/Kdrtm1Jrt
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * C57BL/6J

 MP:0003710 abnormal physiological neovascularization "anomalies in the development of new blood vessels in restoration of blood circulation during the healing process " [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0003799 impaired macrophage migration "defect in the ability of macrophages to move up a chemotactic gradient" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Ptgs2tm1Unc/Ptgs2tm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

 MP:0004230 abnormal embryonic erythrocyte morphology "structural anomaly of the embryonic blood cells that carry oxygen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB

 MP:0004485 increased response of heart to induced stress "increase in severity of the physiological response of the heart to induced stress such as cardiac hypertrophy due to mechanical pressure overload from aortic banding" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0004787 abnormal dorsal aorta morphology "any structural anomaly of the paired arterial structures of the embryo that supplies each developing somite via efferent segmental arteries; the dorsal aortae articulate with the umbilical arteries, which return mixed blood to the villi of the chorion for reoxygenation" [ISBN:0-914294-08-3 "Gray s Anatomy"]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0005425 increased macrophage count "greater than the normal numbers of macrophages" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:73418]
Show

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

 MP:0005542 corneal vascularization "formation of blood vessels in the cornea, which normally lacks vessels" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ptgs2tm1Unc/Ptgs2tm1Unc
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J

Allelic Composition: Flt1tm1Gne/Flt1tm1Gne
Genetic Background: Not Specified

 MP:0005601 increased angiogenesis "enhanced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Kdrtm1Jrt/Kdr+,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129 * C57BL/6NCr * CD-1

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

 MP:0005620 abnormal muscle contractility "aberrant ability of a muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

 MP:0009398 abnormal skeletal muscle fiber size "anomaly in the size of the large multinucleated cells that make up the skeletal muscles" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+,Utrntm1Jrs/Utrntm1Jrs
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C3HA * C57BL/6Ros

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Flt1tm2Msh/Flt1+
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Jak3tm1Flv/Jak3tm1Flv
Genetic Background: involves: 129S1/Sv

 MP:0011204 abnormal visceral yolk sac blood island morphology "any structural anomaly of the masses of developing blood cells attached to endothelium in the yolk sac" [PMID:16140152]
Show

Allelic Composition: Flt1tm1Jrt/Flt1tm1Jrt
Genetic Background: Not Specified

 MP:0012200 increased endothelial cell proliferation 
Show

Allelic Composition: Flt1tm1.1Fong/Flt1tm1.1Fong,Gt(ROSA)26Sortm1(cre/ERT2)Thl/Gt(ROSA)26Sor+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NCr * CD-1

 MP:0012717 increased hemangioblast number "increased number of the pluripotent precursor cells in the yolk sac that can give rise to mesenchymal cells including erythrocytes and endothelial cells; hemangioblasts are the progenitors that form the blood islands" [CL:0002418, MGI:anna]
Show

Allelic Composition: Prrx1tm1Tex/Prrx1tm1Tex,Prrx2tm1Hubr/Prrx2tm1Hubr
Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB

 MP:0020330 increased capillary density "increase in the number of capillaries in a given cross-sectional area of a tissue" [ORCID: orcid.org/0000-0003-4606-0597, PMID:20705734]
Show

Allelic Composition: Dmdmdx-5Cv/Dmdmdx-5Cv,Flt1tm1Jrt/Flt1+
Genetic Background: involves: C3HA * C57BL/6Ros

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000004791 Pgf / P49764 / placental growth factor / P49763*  / complex / reaction
 ENSMUSG00000024962 Vegfb / P49766 / vascular endothelial growth factor B / P49765*  / complex / reaction
 ENSMUSG00000025969 Nrp2 / O35375 / Neuropilin-2 / O60462*  / complex / reaction
 ENSMUSG00000029648 Flt1 / fms related tyrosine kinase 1 / P17948*  / complex / reaction
 ENSMUSG00000023951 Vegfa / Q00731 / vascular endothelial growth factor A / P15692*  / reaction / complex






 

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