ENSMUSG00000054252


Mus musculus

Features
Gene ID: ENSMUSG00000054252
  
Biological name :Fgfr3
  
Synonyms : Fgfr3 / Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 6, mRNA.
  
Possible biological names infered from orthology : fibroblast growth factor receptor 3 / P22607
  
Species: Mus musculus
  
Chr. number: 5
Strand: 1
Band: B2
Gene start: 33721674
Gene end: 33737068
  
Corresponding Affymetrix probe sets: 10521111 (MoGene1.0st)   1421841_at (Mouse Genome 430 2.0 Array)   1425796_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000133064
Ensembl peptide - ENSMUSP00000131845
Ensembl peptide - ENSMUSP00000143797
Ensembl peptide - ENSMUSP00000144379
Ensembl peptide - ENSMUSP00000144104
Ensembl peptide - ENSMUSP00000143963
Ensembl peptide - ENSMUSP00000143945
Ensembl peptide - ENSMUSP00000143936
Ensembl peptide - ENSMUSP00000070998
Ensembl peptide - ENSMUSP00000085122
Ensembl peptide - ENSMUSP00000110053
Ensembl peptide - ENSMUSP00000119941
Ensembl peptide - ENSMUSP00000130856
NCBI entrez gene - 14184     See in Manteia.
MGI - MGI:95524
RefSeq - XM_017320664
RefSeq - XM_006503719
RefSeq - XM_006503720
RefSeq - XM_006503721
RefSeq - XM_006503722
RefSeq - XM_006503723
RefSeq - XM_006503724
RefSeq - XM_006503725
RefSeq - XM_006503726
RefSeq - XM_006503727
RefSeq - XM_006503728
RefSeq - XM_006503729
RefSeq - XM_006503730
RefSeq - XM_006503731
RefSeq - XM_006503732
RefSeq - XM_017320662
RefSeq - XM_017320663
RefSeq - NM_001163215
RefSeq - NM_001163216
RefSeq - NM_001163217
RefSeq - NM_001205270
RefSeq - NM_001359036
RefSeq - NM_008010
RefSeq - XM_006503713
RefSeq - XM_006503714
RefSeq - XM_006503715
RefSeq - XM_006503716
RefSeq - XM_006503717
RefSeq - XM_006503718
RefSeq Peptide - NP_001156689
RefSeq Peptide - NP_001192199
RefSeq Peptide - NP_001345965
RefSeq Peptide - NP_032036
RefSeq Peptide - NP_001156687
RefSeq Peptide - NP_001156688
swissprot - A0A0J9YU04
swissprot - Q7TSI8
swissprot - A0A0J9YTQ5
swissprot - E9QNJ9
swissprot - Q61563
swissprot - D3Z7U5
swissprot - A0A0J9YUX1
swissprot - A0A0J9YUB8
swissprot - A0A0J9YU20
swissprot - F6TK14
Ensembl - ENSMUSG00000054252
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 fgfr3ENSDARG00000004782Danio rerio
 FGFR3ENSGALG00000015708Gallus gallus
 FGFR3ENSG00000068078Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Fgfr2 / fibroblast growth factor receptor 2 isoform 3 / P21802* / fibroblast growth factor receptor 2*ENSMUSG0000003084968
Fgfr1 / P16092 / Fibroblast growth factor receptor 1 / P11362*ENSMUSG0000003156563
Fgfr4 / fibroblast growth factor receptor 4 / P22455*ENSMUSG0000000532059
Kdr / kinase insert domain receptor / P35968*ENSMUSG0000006296032
Flt1 / fms related tyrosine kinase 1 / P17948*ENSMUSG0000002964831
Flt4 / P35917 / Vascular endothelial growth factor receptor 3 / P35916* / fms related tyrosine kinase 4*ENSMUSG0000002035730
Kit / P05532 / Mast/stem cell growth factor receptor Kit / P10721* / KIT proto-oncogene receptor tyrosine kinase*ENSMUSG0000000567229
Csf1r / P09581 / Macrophage colony-stimulating factor 1 receptor / P07333* / colony stimulating factor 1 receptor*ENSMUSG0000002462128
Ret / P35546 / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment / P07949* / ret proto-oncogene*ENSMUSG0000003011028
P26618 / Pdgfra / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA. / P16234* / platelet derived growth factor receptor alpha*ENSMUSG0000002923128
Pdgfrb / platelet-derived growth factor receptor beta isoform 2 / P09619* / platelet derived growth factor receptor beta*ENSMUSG0000002462027
Flt3 / fms related tyrosine kinase 3 / P36888*ENSMUSG0000004281726


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR001245  Serine-threonine/tyrosine-protein kinase, catalytic domain
 IPR003598  Immunoglobulin subtype 2
 IPR003599  Immunoglobulin subtype
 IPR007110  Immunoglobulin-like domain
 IPR008266  Tyrosine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR013098  Immunoglobulin I-set
 IPR013783  Immunoglobulin-like fold
 IPR016248  Fibroblast growth factor receptor family
 IPR017441  Protein kinase, ATP binding site
 IPR020635  Tyrosine-protein kinase, catalytic domain
 IPR036179  Immunoglobulin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007267 cell-cell signaling IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008543 fibroblast growth factor receptor signaling pathway IEA
 biological_processGO:0010518 positive regulation of phospholipase activity IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity IEA
 biological_processGO:0046777 protein autophosphorylation IEA
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IEA
 biological_processGO:1902178 fibroblast growth factor receptor apoptotic signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005783 endoplasmic reticulum IEA
 cellular_componentGO:0005794 Golgi apparatus IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030133 transport vesicle IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0005007 fibroblast growth factor-activated receptor activity IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0017134 fibroblast growth factor binding IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
PI3K Cascade
PIP3 activates AKT signaling
FGFR3b ligand binding and activation
FGFR3c ligand binding and activation
Phospholipase C-mediated cascade; FGFR3
FRS-mediated FGFR1 signaling
FRS-mediated FGFR2 signaling
SHC-mediated cascade:FGFR3
FRS-mediated FGFR3 signaling
PI-3K cascade:FGFR3
FRS-mediated FGFR4 signaling
Negative regulation of FGFR3 signaling
RAF/MAP kinase cascade
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000029 abnormal malleus morphology "structural anomaly in the largest of the three auditory ossicles, which resembles a club or hammer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000031 abnormal cochlea morphology "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000042 abnormal organ of Corti "abnormalities associated with the highly specialized epithelium in the floor of the ductus cochlearis; also referred to a spiral organ (organum spirale), or acoustic papilla" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000060 delayed bone ossification "late onset of the formation of bone" [J:40203]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0000063 reduced bone density "decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm6.2Cxd/Fgfr3tm6.2Cxd
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0000069 kyphoscoliosis "kyphosis combined with scoliosis" [MGI:CML, J:66943]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0000074 abnormal neurocranium morphology "malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000109 abnormal parietal bone morphology "malformed curved bone forming part of the vault of the cranium" [J:17489]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

 MP:0000120 malocclusion "perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0000131 abnormal long bone epiphysis morphology "the head of a developing long bone that is separated from the shaft by the epiphyseal plate" [J:61509]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0000133 abnormal long bone metaphysis morphology "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0000135 reduced cortical bone thickness "thinner than normal superficial layer of compact bone " [J:61509]
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Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000137 abnormal vertebrae morphology "malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0000150 abnormal rib morphology "malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000160 kyphosis "forward curvature of the spine, characterized by extensive flexion. " [J:62023, J:66943, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0000161 scoliosis "lateral and rotational curvature of the spine" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53770, J:66943]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0000165 abnormal hypertrophic chondrocyte zone "anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0000166 abnormal chondrocyte morphology "anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0000167 reduced chondrocyte numbers "fewer than normal numbers of nondividing cartilage cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61509]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000428 abnormal craniofacial morphology "anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Lig4tm1Pmc/Lig4tm1Pmc,Trp53tm1Tyj/Trp53+,Xrcc2tm2Pmc/Xrcc2tm2Pmc,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: C.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: C.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000434 megacephaly "an abnormally large size of the head" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0000438 abnormal skull morphology "anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000440 domed skull 
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0000441 wide skull 
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000443 abnormal snout morphology "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000445 short snout "reduced length of the anterior facial part of the muzzle" [J:53370]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0000455 abnormal maxilla morphology "malformation of the upper bony framework of the mouth where the superior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

 MP:0000540 abnormal urinary bladder epithelium morphology "malformation of the epithelial layer of the urinary bladder" [MGI:tc]
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N

 MP:0000547 short limbs "reduced average length of the extremities" [MGI:CLS, J:61509]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0000548 long limbs "increased average length of the extremities" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0000558 abnormal tibia morphology "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0000559 abnormal femur morphology "structural anomaly of the long bone of the thigh" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0000566 synostosis "osseous union of two bones that are not normally connected" [J:13049]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0000585 kinked tail "a sharp bend or zig-zag in the tail" [J:61295]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm6Cxd/Fgfr3tm6Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0000592 short tail "reduced length of tail compared to control " [J:55583]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0001184 absent alveoli "missing section of the lung in which gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001258 decreased body length "decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Igh-Jtm1Mcdl/Igh-Jtm1Mcdl,Igk-Jtm1Mcdl/Igk-Jtm1Mcdl,Rag1tm1Mom/Rag1tm1Mom,Tg(DO11.10)10Dlo/?
Genetic Background: involves: 129S/Sv * BALB/c * C3H * C57BL/6

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Glg1tm1Brle/Glg1tm1Brle
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0001300 ocular hypertelorism "increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0001406 abnormal gait "unusual or distinctive way of walking" [J:65038]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0001429 dehydration "excessive water loss from the body or from an organ or bodily part" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50053]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001541 abnormal osteoclast function "reduced ability or inability of osteoclasts to absorb and remove osseous tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001923 reduced female fertility "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0001924 infertility "inability to produce live offspring" [J:47225]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0001951 abnormal breathing "irregular or atypical breathing pattern " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17489]
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Allelic Composition: Mstntm2Sjl/Mstntm2Sjl
Genetic Background: B6.129-Mstntm2Sjl

Allelic Composition: Fgfr3tm5Cxd/Fgfr3tm5Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0001954 respiratory distress "physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0001958 emphysema "lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33629]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001967 deafness "inability to hear" [J:57651]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0002051 skin papilloma "a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm4Cxd/Fgfr3+,Krastm4Tyj/Kras+,Tg(Upk2-cre)6Xrw/0
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dstdt-38J/Dstdt-38J
Genetic Background: involves: BALB/cByJ * C57BL/6J

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Fgfr3tm4Cxd/Fgfr3+,Krastm4Tyj/Kras+,Tg(Upk2-cre)6Xrw/0
Genetic Background: involves: 129S4/SvJae * 129S6/SvEvTac * FVB/N

Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N

 MP:0002089 abnormal postnatal growth/weight/body size "increased or decreased average body size, weight or growth characteristic abnormalities manifesting after birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mstntm2Sjl/Mstntm2Sjl
Genetic Background: B6.129-Mstntm2Sjl

Allelic Composition: Fgfr3tm5Cxd/Fgfr3tm5Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0002111 abnormal tail morphology "abnormal development of the tail resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ins1tm1Jja/Ins1tm1Jja,Ins2tm1Jja/Ins2+
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0002113 abnormal skeleton development "anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0002114 abnormal axial skeleton morphology "abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Dstdt-38J/Dstdt-38J
Genetic Background: involves: BALB/cByJ * C57BL/6J

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0002116 abnormal craniofacial bone morphology "abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Fgfr3tm1Cxd/Fgfr3tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Aomw/Fgfr3+
Genetic Background: involves: 129P2/OlaHsd

 MP:0002187 abnormal fibula morphology "malformation of the lateral and smaller bone of the lower limb" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0002427 dwarfism "abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Fgfr3tm1Cxd/Fgfr3tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0002622 abnormal cochlear hair cell morphology "malformation of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Mcoln3Va/Mcoln3Va
Genetic Background: involves: C57BL * C57BR

 MP:0002758 long tail "increased length of tail relative to average of a given strain" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:82849]
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Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0002764 short tibia " reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0002820 abnormal premaxilla morphology "malformation or absence of the anterior and inner portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:76662]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0002835 abnormal cranial suture morphology "defects of the fibrous joint in the bones of the head" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62161]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0002896 abnormal bone mineralization "defect in the process by which minerals are deposited into bone" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003047 abnormal thoracic vertebrae morphology "malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0003048 abnormal cervical vertebrae morphology "malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0003055 abnormal epiphyseal plate morphology "malformed or absent cartilagenous center of ossification on the long bones permitting growth of the bone in both directions during development" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Fgfr3tm1Cxd/Fgfr3tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003109 short femur "reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0003151 absent tunnel of Corti "complete absence of the triangular, fluid-filled space normally found between the inner and outer rows of supporting pillar cells in the organ of Corti" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:32991]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0003152 abnormal pillar cell differentiation "abnormal differentiation of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti" [J:32991, anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0003209 abnormal pulmonary elastic fiber morphology "malformation of a slender connective tissue fiber in pulmonary tissue characterized by great elasticity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003308 abnormal cochlear sensory epithelium 
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0003408 increased width of hypertrophic chondrocyte zone "increased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0003409 decreased width of hypertrophic chondrocyte zone "decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003417 premature endochondral bone ossification "early onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0003419 delayed endochondral bone ossification "late onset of bone formation in bones that form from cartilage" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0003662 abnormal proliferative zone "germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003723 abnormal long bone morphology "malformation of any of the several elongated bones of the extremities " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003795 abnormal bone structure 
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Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0003825 abnormal pillar cell morphology "abnormalities of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0003840 abnormal coronal suture morphology "malformation of the articulation between the parietal bones and the frontal bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0003841 abnormal lambdoidal suture morphology "malformation of the articulation of the parietal bones and the occipital bone" [Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0003843 abnormal sagittal suture morphology "malformation of the articulation between the parietal bones" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0004053 abnormal synchondrosis "anomalous or persistent cartilagenous fusion of two bones " [J:102870, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0004174 abnormal spine curvature "deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0004214 abnormal long bone diaphysis morphology "any structural anomaly of the main or mid section (shaft) of a long bone" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0004302 abnormal Dieters cell morphology "any structural abnormality in the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004312 absent pillar cells "absence of the supporting cells that form the inner and outer walls of the tunnel in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0004348 long femur "increased length of the long bone of the thigh" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

Allelic Composition: Fgfr3tm6.2Cxd/Fgfr3tm6.2Cxd
Genetic Background: involves: 129S6/SvEvTac * FVB/N

 MP:0004350 long humerus "increased length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0004351 short humerus "reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0004355 short radius "reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0004357 long tibia "increased length of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0004358 bowed tibia "increased curvature of the medial and larger of the two bones of the lower leg" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004359 short ulna "reduced length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0004361 bowed ulna "increased curvature of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004370 long ulna "increased length of the medial and larger of the two bones of the forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Schl/Fgfr3tm2Schl
Genetic Background: involves: 129S1/Sv * CD-1 * FVB/N

 MP:0004371 bowed femur "increased curvature of the long bone of the thigh" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0004372 bowed fibula "increased curvature of the lateral and smaller bone of the lower limb" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004373 bowed humerus "increased curvature of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004374 bowed radius "increased curvature of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004380 short frontal bone "reduced length of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

 MP:0004384 small interparietal bone "reduced size of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0004386 enlarged interparietal bone "increased size of the bone of the cranium that lies above and anterior to the occipital bone in some mammals" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0004399 abnormal cochlear outer hair cell morphology "any structural abnormality in the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there are three rows of columnar outer hair cells largely surrounded by cortilymph and supporting phalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a V-shaped pattern extend from the cell s surface through the cuticular plate into the tectorial membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004401 increased cochlear outer hair cell number "increased number (or more than the expected 3 rows) of the columnar outer hair sensory cells of the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0004441 small occipital bone "reduced size of the bone at the lower, posterior part of the skull" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0004471 short nasal bone "reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0004537 abnormal palatine shelf "any structural anomaly of the palatine bone; normally fuses with maxillary shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0004610 small vertebrae "reduced size of the bony segments of the spinal column" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0004624 abnormal thoracic cage "any structural anomaly of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0004626 vertebral compression "appearance of vertebrae that are flattened laterally along the whole length such that they appear pressed together and take up less rostrocaudal space " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0004632 abnormal cochlear OHC efferent innervation "any changes in the morphology or number of efferent terminals, occurring as clusters, in the cochlear OHC region; normally, medial olivocochlear neurons, which are primarily found in rostral and ventral periolivary regions, project mainly to the contralateral cochlea, and terminate directly on OHCs" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004652 small caudal vertebrae "reduced size of the bony segments of the coccyx or tail; there are usually 27-30 present in rodents and only 3-5 fused vertebrae in human" [MESH:National Library of Medicine_Medical Subject Headings]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0004669 enlarged vertebral body "increased size of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004672 short ribs "reduced length of the bones forming the bony wall of the chest" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0004686 decreased length of long bones "reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0004704 short vertebral column "decreased rostral-caudal length of the complete structure forming the rostral-caudal axis of the skeleton formed from the alternating segments of vertebra and intervertebral discs which support the spinal cord" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004705 elongated vertebral body "increased length of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0004706 short vertebral body "reduced length of the main cylindrical portion of the vertebra ventral to the vertebral canal" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

 MP:0004708 short lumbar vertebrae "reduced length of any or all of the six bony segments of the spine located anterior to the sacral vertebrae and posterior to the thoracic vertebrae" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0004734 small thoracic cavity "reduced size of the cavity in the vertebrate body enclosed by the ribcage between the diaphragm and the neck, and contains the lungs, heart, thoracic aorta, pulmonary artery and its branches, thymus gland, and the respiratory airway" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0004740 sensorineural hearing loss "a form of progressive hearing loss due to a lesion of the auditory division of cranial nerve VIII or the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0004831 long incisors "increased length of the long pointed teeth; most anterior and prominent in the jaw" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0004840 increased Dieters cell number "increased number of the supporting cells of the spiral organ which are attached to the basement membrane and receive the hair cells between their free extremities" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

 MP:0004924 abnormal behavior "anomalies in the actions, reactions, or performance of an organism in response to external or internal stimuli compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm3Cxd/Fgfr3tm3Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5Cxd/Fgfr3tm5Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0005006 abnormal osteoblast function "anomalous function of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0005105 abnormal middle ear ossicle morphology "anomalous structure or development of the three small bones of the middle ear" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005106 abnormal incus morphology "structural anomaly of the middle of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005107 abnormal stapes morphology "structural anomaly of the smallest and innermost of the three auditory ossicles" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005108 abnormal ulna morphology "malformation of the medial and larger of the two bones of the forearm" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:83132]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0005269 abnormal occipital bone morphology "anomalous structure of the bone at the lower, posterior part of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

 MP:0005270 abnormal zygomatic bone morphology "anomalous structure of the bone that forms the prominence of the cheek" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0005272 abnormal temporal bone morphology "anomalous structure of the large, irregular bone located at the base and side of the skull; consists of three parts at birth: squamous, tympanic, and petrous" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0005296 abnormal humerus morphology "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005508 abnormal skeleton morphology "malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Cdkn1atm1Led/Cdkn1atm1Led,Fgfr3tm1Cxd/Fgfr3tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm4Cxd/Fgfr3+,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL

Allelic Composition: Fgfr3tm3Cxd/Fgfr3tm3Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5Cxd/Fgfr3tm5Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0006027 impaired alveologenesis "a block or reduction in the generation of alveoli" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:85546]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm4Cxd/Fgfr3+,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Fgfr4tm1Cxd/Fgfr4tm1Cxd
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0006325 impaired hearing "reduced ability to percieve auditory stimuli" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: C.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgf8tm1Mrc/Fgf8+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

Allelic Composition: Fgf8tm1Mrc/Fgf8+,Fgf9tm1Dor/Fgf9+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

Allelic Composition: Fgf9tm1Dor/Fgf9+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

 MP:0006331 abnormal patterning of the organ of Corti "anomaly in the organization of the various cell types within the organ of Corti into a set number of distinct rows" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0006394 abnormal vertebral epiphyseal plate morphology "any structural anomaly in the lateral cartilaginous centers of ossification; may be found on the lateral, upper, and/or lower surfaces of the vertebrae at different times during development" [ISBN:0-914294-08-3 "Gray s Anatomy", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0006395 abnormal epiphyseal plate morphology "any structural anomaly of the cartilaginous center of ossification on the bones permitting growth of the bone in both directions during development" [MESH:A02.835.232.251.352]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0006396 decreased long bone epiphyseal plate size "reduced size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led,Glg1tm1Brle/Glg1tm1Brle
Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd * C57BL/6J

 MP:0006397 disorganized long bone epiphyseal plate "a lack of the regular arrangement of the cells or zones of the epiphyseal plate" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0006398 increased long bone epiphyseal plate size "greater than the normal size of the cartilaginous center of ossification on the long bones permitting growth of the bone in both directions during development" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ccne1tm1Jro/?,Krastm3Tyj/?
Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Wei/Fgfr3tm1Wei
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0006399 abnormal long bone epiphyseal ossification zone morphology "any anomaly in the structure of the layer of the epiphyseal plate where new bone matrix is deposited" [CALnet tutorial:http://137.222.110.150/calnet/Introanat/Introanat.htm, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Fgfr3tm2Llm/Fgfr3+,Tg(Col2a1-cre)1Bhr/?
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0006429 abnormal hyaline cartilage morphology "any structural anomaly of the bluish-white, glassy, translucent nonvascular, resilient, flexible connective tissue; found primarily in articular cartilage, costal cartilages, the nasal septum, the larynx, and the trachea" [ISBN:0-8036-0655-9 "Taber s Cyclopedic Medical Dictionary", MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

 MP:0006432 abnormal costal cartilage morphology "any structural anomaly of the nonvascular, resilient, flexible connective tissue that connects the end of a true rib to the sternum or the end of a false rib with the costal cartilage above" [ISBN:0-8036-0655-9 "Taber s Cyclopedic Medical Dictionary", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0008014 lung tumor "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Fgfr3tm4Cxd/Fgfr3+,Tg(Upk2-cre)6Xrw/0
Genetic Background: involves: 129S6/SvEvTac * 129X1/SvJ * FVB/N

 MP:0008151 increased diameter of long bones "increased width of the cross-sectional distance that extends from one lateral edge of a long bone, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0008158 increased diameter of femur "increased width of the cross-sectional distance that extends from one lateral edge of the femur, through its center and to the opposite lateral edge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0008271 abnormal bone ossification "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0008272 abnormal endochondral bone ossification "anomaly in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0008273 abnormal intramembranous bone ossification "anomaly in the process of the formation of bone in which osteoblasts secrete a collage-proteoglycan matrix that binds calcium salts and becomes calcified; intramembranous ossification is the way flat bones are formed" [GO:0001957]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0008277 abnormal sternum ossification "anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

 MP:0008278 failure of sternum ossification "failure to initiate or a block in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0008304 abnormal supporting cell differentiation "atypical production of or inability to produce the highly differentiated epithelial cells with distinctive morphological features that surround the hair cells in the organ of Corti" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0008525 decreased skull height "decrease in the distance between the cranial base and the upper domelike portion of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0008951 long radius "increased length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac

 MP:0009546 absent gastric milk in neonates "failure of nursing offspring to ingest milk as indicated by stomach content" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0009780 abnormal chondrocyte physiology "any functional anomaly of nondividing cartilage cells" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm6Cxd/Fgfr3tm6Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0009911 increased hyoid bone size "greater size of the U-shaped bone lying between the mandible and the larynx that supports the tongue muscles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

 MP:0010099 abnormal thoracic cage shape "anomaly in the overall regular dome shape of the ribcage" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0010103 small thoracic cage "reduced size of the bony and cartilaginous structure enclosing the thoracic cavity, consisting of the thoracic vertebrae, ribs, costal cartilages, and sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0010208 prognathia "abnormal protrusion of the mandible relative to the facial skeleton and soft tissues" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0010282 decreased organ/body region tumor incidence "less than the expected number of tumors originating in a specific body region or organ in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Jak2tm2.2Jlvl/Jak2+
Genetic Background: involves: 129S2/SvPas * C57BL/6 * C57BL/6NTac * SJL

 MP:0010941 abnormal foramen magnum morphology "any structural anomaly of the large orifice in the occipital bone through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0011083 complete lethality at weaning "premature death at weaning age of all organisms of a given genotype in a population, often due to the inability to make the transition to solid food" [MGI:csmith]
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Allelic Composition: Fgfr3tm3Cxd/Fgfr3tm3Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5Cxd/Fgfr3tm5Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0011084 partial lethality at weaning "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0011086 partial postnatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011087 complete neonatal lethality "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor,Pthlhtm1Fbe/Pthlhtm1Fbe
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: Fgfr3tm4Cxd/Fgfr3+,Tg(Col2a1-cre)1Bhr/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * NIH Black Swiss * SJL

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0011091 complete prenatal lethality "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Rab27aash-N/Rab27aash-N
Genetic Background: B10.F

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3tm1.1Iwa
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss * CD-1 * FVB/N

 MP:0011496 abnormal head size "anomaly in the average size of the portion of the body containing the brain and organs of sight, hearing, taste, and smell" [MGI:csmith]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0011703 increased fibroblast proliferation "greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0011710 increased osteoblast differentiation 
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0011967 increased or absent threshold for auditory brainstem response "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith]
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Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

Allelic Composition: Fgfr3tm1Dor/Fgfr3tm1Dor
Genetic Background: CBA/Ca.129S6(B6)-Fgfr3tm1Dor

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: C.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: CBA/Ca.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgf8tm1Mrc/Fgf8+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

Allelic Composition: Fgf8tm1Mrc/Fgf8+,Fgf9tm1Dor/Fgf9+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

Allelic Composition: Fgf9tm1Dor/Fgf9+,Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: involves: 129 * BALB/c * C57BL/6

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0012085 midface hypoplasia "underdevelopment of the midfacial region comprising the nasal, maxillary, and zygomatic bones, leading to a concave-looking face" [MGI:anna]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0012279 wide sternum "an increase in the width of the long flat bone of the chest that articulates with the clavicle and first seven rib pairs" [MGI:anna]
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Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0012556 increased cell death "increased occurrence of the cessation of function at the cellular level" [http://orcid.org/0000-0001-5208-3432]
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Allelic Composition: Foxg1tm1(cre)Skm/Foxg1+,Frs2tm1Fwan/Frs2tm1Fwan,Frs3tm1Jheb/Frs3tm1Jheb
Genetic Background: involves: 129 * Swiss Webster

 MP:0012683 absent telencephalon "absence of the enlarged anteriolateral part of the brain; consists of the paired cerebral hemispheres and olfactory bulbs, the basal ganglia and the connecting structures" [MGI:anna]
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Allelic Composition: Foxg1tm1(cre)Skm/Foxg1+,Frs2tm1Fwan/Frs2tm1Fwan,Frs3tm1Jheb/Frs3tm1Jheb
Genetic Background: involves: 129 * Swiss Webster

Allelic Composition: Fgfr2tm1Dor/Fgfr2tm1Dor,Fgfr3tm6.1Cxd/Fgfr3tm6.1Cxd,Foxg1tm1(cre)Skm/Foxg1+,Fgfr1tm3.1Sor/Fgfr1tm1Jpa
Genetic Background: involves: 129

 MP:0013176 abnormal tail position or orientation " tail is displaced from the normal location and/or does not orient in a typical pattern" [MGI:anna]
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Allelic Composition: Fgfr3m1J/Fgfr3m1J
Genetic Background: CByJ.Cg-Fgfr3m1J/GrsrJ

 MP:0013179 wavy tail "undulations or a sinusoidal shape of the tail" [MGI:anna]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0014099 abnormal chondrocyte proliferation "any anomaly in multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population" [GO:0035988]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

 MP:0014100 increased chondrocyte proliferation "increased amount of multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population" [GO:0035988]
Show

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0014101 decreased chondrocyte proliferation "decreased amount of multiplication or reproduction of chondrocytes by cell division, resulting in the expansion of their population" [GO:0035988]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0014105 abnormal chondrocyte differentiation "any anomaly in the process in which a chondroblast acquires specialized structural and/or functional features of a chondrocyte" [GO:0002062]
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Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0020039 increased bone ossification "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597]
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Allelic Composition: Fgfr3tm1Led/Fgfr3tm1Led
Genetic Background: involves: 129S6/SvEvTac

 MP:0030094 foramen magnum stenosis "abnormal narrowing or constriction of the large orifice in the occipital bone through which the spinal cord passes to the cranial cavity and becomes continuous with the medulla oblongata" [MGI:anna]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0030190 small snout "decreased size of the anterior facial part of the face or muzzle containing the oral and nasal regions" [MGI:anna]
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Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas

 MP:0030245 round head "overall shape of the head is more circular than usual as viewed from the front" [MGI:anna]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

Allelic Composition: Fgfr3tm1.1Iwa/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * FVB/N * NIH Black Swiss

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm4.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss

 MP:0030274 maxillary retrognathia "abnormal posterior-shifted positioning of the upper jaw (maxilla) relative to the facial skeleton and soft tissues" [MGI:anna]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0030275 thin frontal bone "reduced thickness of the single bone forming the forehead and roof of the eye orbit" [MGI:anna]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0030281 thin parietal bone "reduced thickness of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium" [MGI:anna]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: B6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0030302 abnormal maxillary zygomatic process morphology "any structural anomaly of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [https://en.wikipedia.org/wiki/Zygomatic_process_of_maxilla]
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Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3tm1.1Aomw
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

Allelic Composition: Fgfr3tm1.1Aomw/Fgfr3+
Genetic Background: 129S6.129P2-Fgfr3tm1.1Aomw

 MP:0030383 small presphenoid bone "reduced size of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [MGI:anna]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

 MP:0030420 short basicranium "decreased length of the anterior and/or posterior portions of the skull base" [MGI:anna]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm1Llm/Fgfr3+
Genetic Background: involves: 129S2/SvPas * C57BL/6J

 MP:0030444 premature cranial synchondrosis closure "early fusion or ossification of one or more cranial base synchondroses relative to age- and gender-matched controls; can lead to midface hypoplasia, as seen in patients with specific forms of syndromic craniosynostosis" [PMID:24480760]
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Allelic Composition: Fgfr3tm3.1Cxd/Fgfr3tm3.1Cxd
Genetic Background: involves: 129S6/SvEvTac

Allelic Composition: Fgfr3tm5.1Cxd/Fgfr3+
Genetic Background: involves: 129S6/SvEvTac

 MP:0030541 misaligned incisors "abnormal alignment of the upper and lower incisor teeth, usually resulting in malocclusion; in gnawing rodents, where incisors are rootless and grow continually, signs of incisor malocclusion include uneven wear patterns, sloping of the cutting edges, fractured teeth, altered pigmentation, and obvious pathological overgrowth of the incisors" [HP:0011062, https://books.google.com/books?isbn=0323394302, PMID:19622764]
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Allelic Composition: Fgfr3tm2Wei/Fgfr3+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * MF1

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
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