Manteia - Molecule gene

ENSMUSG00000030849

Mus musculus

Features

Gene ID:	ENSMUSG00000030849

Biological name :	Fgfr2

Synonyms :	Fgfr2 / fibroblast growth factor receptor 2 isoform 3

Possible biological names infered from orthology :	fibroblast growth factor receptor 2 / P21802

Species:	Mus musculus

Chr. number:	7
Strand:	-1
Band:	F3
Gene start:	130162451
Gene end:	133123350

Corresponding Affymetrix probe sets:	10568436 (MoGene1.0st) 1420847_a_at (Mouse Genome 430 2.0 Array) 1433489_s_at (Mouse Genome 430 2.0 Array) 1443211_at (Mouse Genome 430 2.0 Array)

Cross references:	Ensembl peptide - ENSMUSP00000112580 Ensembl peptide - ENSMUSP00000112471 Ensembl peptide - ENSMUSP00000112585 Ensembl peptide - ENSMUSP00000130971 Ensembl peptide - ENSMUSP00000122856 Ensembl peptide - ENSMUSP00000120100 Ensembl peptide - ENSMUSP00000113994 Ensembl peptide - ENSMUSP00000113993 Ensembl peptide - ENSMUSP00000113474 Ensembl peptide - ENSMUSP00000113452 Ensembl peptide - ENSMUSP00000113415 Ensembl peptide - ENSMUSP00000113248 Ensembl peptide - ENSMUSP00000113187 Ensembl peptide - ENSMUSP00000113180 Ensembl peptide - ENSMUSP00000113010 Ensembl peptide - ENSMUSP00000112992 Ensembl peptide - ENSMUSP00000112672 Ensembl peptide - ENSMUSP00000112623 Ensembl peptide - ENSMUSP00000112430 NCBI entrez gene - 14183 See in Manteia. MGI - MGI:95523 RefSeq - XM_017321977 RefSeq - NM_010207 RefSeq - NM_201601 RefSeq - XM_006507349 RefSeq - XM_006507350 RefSeq - XM_006507352 RefSeq - XM_006507354 RefSeq - XM_006507357 RefSeq - XM_006507359 RefSeq - XM_011241673 RefSeq - XM_011241674 RefSeq - XM_011241675 RefSeq - XM_011241676 RefSeq - XM_011241677 RefSeq - XM_017321975 RefSeq - XM_017321976 RefSeq Peptide - NP_963895 RefSeq Peptide - NP_001334567 RefSeq Peptide - NP_034337 swissprot - D3Z5M8 swissprot - E9QK53 swissprot - E9Q7T0 swissprot - E9Q7E8 swissprot - E9Q7E6 swissprot - E9Q7C7 swissprot - E9Q708 swissprot - E9Q700 swissprot - E9Q5C3 swissprot - E9Q5C2 swissprot - E9PXV8 swissprot - E9PX90 swissprot - E9PX88 swissprot - E9PX67 swissprot - E9PX60 swissprot - F2Z480 swissprot - E9PVU6 swissprot - F7BDU9 swissprot - D6RJK5 Ensembl - ENSMUSG00000030849

See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed

Ortholog prediction (from Ensembl)

Ortholog name	ID	Species
fgfr2	ENSDARG00000058115	Danio rerio
FGFR2	ENSGALG00000009495	Gallus gallus
FGFR2	ENSG00000066468	Homo sapiens

Paralog prediction (from Ensembl)

Paralog name	ID	Similarity(%)
Fgfr1 / P16092 / Fibroblast growth factor receptor 1 / P11362*	ENSMUSG00000031565	70
Fgfr3 / Mus musculus fibroblast growth factor receptor 3 (Fgfr3), transcript variant 6, mRNA. / P22607* / fibroblast growth factor receptor 3*	ENSMUSG00000054252	65
Fgfr4 / fibroblast growth factor receptor 4 / P22455*	ENSMUSG00000005320	54
Flt1 / fms related tyrosine kinase 1 / P17948*	ENSMUSG00000029648	31
Kdr / kinase insert domain receptor / P35968*	ENSMUSG00000062960	30
Flt4 / P35917 / Vascular endothelial growth factor receptor 3 / P35916* / fms related tyrosine kinase 4*	ENSMUSG00000020357	29
Kit / P05532 / Mast/stem cell growth factor receptor Kit / P10721* / KIT proto-oncogene receptor tyrosine kinase*	ENSMUSG00000005672	28
Ret / P35546 / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment / P07949* / ret proto-oncogene*	ENSMUSG00000030110	28
P26618 / Pdgfra / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA. / P16234* / platelet derived growth factor receptor alpha*	ENSMUSG00000029231	27
Csf1r / P09581 / Macrophage colony-stimulating factor 1 receptor / P07333* / colony stimulating factor 1 receptor*	ENSMUSG00000024621	27
Pdgfrb / platelet-derived growth factor receptor beta isoform 2 / P09619* / platelet derived growth factor receptor beta*	ENSMUSG00000024620	26
Flt3 / fms related tyrosine kinase 3 / P36888*	ENSMUSG00000042817	25

Protein motifs (from Interpro)

Interpro ID	Name
IPR000719	Protein kinase domain
IPR001245	Serine-threonine/tyrosine-protein kinase, catalytic domain
IPR003598	Immunoglobulin subtype 2
IPR003599	Immunoglobulin subtype
IPR007110	Immunoglobulin-like domain
IPR008266	Tyrosine-protein kinase, active site
IPR011009	Protein kinase-like domain superfamily
IPR013098	Immunoglobulin I-set
IPR013783	Immunoglobulin-like fold
IPR016248	Fibroblast growth factor receptor family
IPR017441	Protein kinase, ATP binding site
IPR020635	Tyrosine-protein kinase, catalytic domain
IPR036179	Immunoglobulin-like domain superfamily

Gene Ontology (GO)

Type	GO ID	Term	Ev.Code
biological_process	GO:0001837	epithelial to mesenchymal transition	IEA
biological_process	GO:0003416	endochondral bone growth	IEA
biological_process	GO:0006468	protein phosphorylation	IEA
biological_process	GO:0008284	positive regulation of cell proliferation	IEA
biological_process	GO:0008543	fibroblast growth factor receptor signaling pathway	IEA
biological_process	GO:0010518	positive regulation of phospholipase activity	IEA
biological_process	GO:0016310	phosphorylation	IEA
biological_process	GO:0018108	peptidyl-tyrosine phosphorylation	IEA
biological_process	GO:0032496	response to lipopolysaccharide	IEA
biological_process	GO:0042060	wound healing	IEA
biological_process	GO:0043410	positive regulation of MAPK cascade	IEA
biological_process	GO:0044344	cellular response to fibroblast growth factor stimulus	IEA
biological_process	GO:0045471	response to ethanol	IEA
biological_process	GO:0046777	protein autophosphorylation	IEA
biological_process	GO:0048333	mesodermal cell differentiation	IEA
biological_process	GO:0048661	positive regulation of smooth muscle cell proliferation	IEA
biological_process	GO:0048701	embryonic cranial skeleton morphogenesis	IEA
biological_process	GO:0050680	negative regulation of epithelial cell proliferation	IEA
biological_process	GO:0071300	cellular response to retinoic acid	IEA
biological_process	GO:0071560	cellular response to transforming growth factor beta stimulus	IEA
cellular_component	GO:0005634	nucleus	IEA
cellular_component	GO:0005654	nucleoplasm	IEA
cellular_component	GO:0005737	cytoplasm	IEA
cellular_component	GO:0005887	integral component of plasma membrane	IEA
cellular_component	GO:0005938	cell cortex	IEA
cellular_component	GO:0009986	cell surface	IEA
cellular_component	GO:0016020	membrane	IEA
cellular_component	GO:0016021	integral component of membrane	IEA
cellular_component	GO:0031012	extracellular matrix	IEA
cellular_component	GO:0043231	intracellular membrane-bounded organelle	IEA
molecular_function	GO:0000166	nucleotide binding	IEA
molecular_function	GO:0004672	protein kinase activity	IEA
molecular_function	GO:0004713	protein tyrosine kinase activity	IEA
molecular_function	GO:0004714	transmembrane receptor protein tyrosine kinase activity	IEA
molecular_function	GO:0005007	fibroblast growth factor-activated receptor activity	IEA
molecular_function	GO:0005524	ATP binding	IEA
molecular_function	GO:0016301	kinase activity	IEA
molecular_function	GO:0016740	transferase activity	IEA
molecular_function	GO:0017134	fibroblast growth factor binding	IEA
molecular_function	GO:0042803	protein homodimerization activity	IEA

Pathways (from Reactome)

Pathway description

PIP3 activates AKT signaling

FGFR2c ligand binding and activation

FGFR2b ligand binding and activation

Phospholipase C-mediated cascade; FGFR2

FRS-mediated FGFR1 signaling

PI-3K cascade:FGFR2

SHC-mediated cascade:FGFR2

FRS-mediated FGFR2 signaling

FRS-mediated FGFR3 signaling

FRS-mediated FGFR4 signaling

Negative regulation of FGFR2 signaling

RAF/MAP kinase cascade

PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling

Phenotype (from MGI, Zfin or HPO)

ID	Phenotype	Definition	Genetic BG
MP:0000031	abnormal cochlea morphology	"any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000035	abnormal membranous labyrinth	"malformations in the complex arrangement of communicating canaliculi and sacs suspended within the cavity of the bony labyrinth of the inner ear" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23837]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000039	abnormal otic capsule morphology	"malformation of the cartilage or bony capsule surrounding the inner ear mechanism" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:23837]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000060	delayed bone ossification	"late onset of the formation of bone" [J:40203]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0000063	reduced bone density	"decreased mineral content of bone; indicator of bone strength" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:57315]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0000074	abnormal neurocranium morphology	"malformed bones of the skull enclosing the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0000077	abnormal interparietal bone morphology	"malformed bone of the cranium; lies above and anterior to the occipital bone " [J:61509]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0000081	premature suture closure	"early fusion of the bones of the skull" [J:26513]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm1Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0000088	short mandible	"reduced length of the lower bony framework of the mouth where the inferior teeth are held" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0000097	short maxilla	"reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0000102	abnormal nasal bone morphology	"malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0000104	abnormal sphenoid bone morphology	"malformed irregularly shaped bone of the base of the skull" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0000106	abnormal basisphenoid bone morphology	"malformed base of the sphenoid bone" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55583]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000107	abnormal frontal bone morphology	"malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm2Schl/Fgfr2^tm2Schl Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6
MP:0000118	arrest of tooth development	"failure of differentiation of the teeth" [J:18378]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000120	malocclusion	"perturbations in the normal patterned arrangement of the teeth or alignment of the jaw, resulting in the incorrect position of biting or chewing surfaces of the upper and lower teeth" [J:61509]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000124	absent teeth	"missing bony structures of the upper and lower jaws used in mastication" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000130	abnormal cancellous bone morphology	"structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Sfrp4^tm1.1Blan/Sfrp4⁺ Genetic Background: Not Specified
MP:0000133	abnormal long bone metaphysis morphology	"malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0000137	abnormal vertebrae morphology	"malformed bony segment of the spinal column" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000149	abnormal scapula morphology	"malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000157	abnormal sternum morphology	"malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0000159	abnormal xiphoid process	"malformed posterior tip of the sternum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:42932]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000163	abnormal cartilage morphology	"anomalous structure or development of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0000164	abnormal cartilage development	"anomalous formation of the nonvascular, resilient, flexible connective tissue found primarily in joints, walls of the throax, and tubular structures, but which also comprises most of the skeleton in early fetal life " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0000165	abnormal hypertrophic chondrocyte zone	"anomaly of the cartilage cell matrix layer " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58795]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0000166	abnormal chondrocyte morphology	"anomalous structure, organization, or differentiation of nondividing cartilage cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000189	hypoglycemia	"low levels of plasma glucose in the circulating blood; this generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0000259	abnormal vascular development	"malformation or aberrant differentiation of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17509]	Show Allelic Composition: Mesp1^tm2(cre)Ysa/Mesp1⁺,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 Genetic Background: Not Specified
MP:0000267	abnormal cardiac development	"aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000273	overriding aorta	"congenitally mispositioned aorta where the origin straddles the ventral septum and so receives ejected blood from the right ventricle as well as the left." [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cml, J:67826]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000279	ventricular hypoplasia	"reduction in cell number of one or both of the two lower chambers of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000280	thin ventricular wall	"decreased depth of the cardiac wall of the heart ventricles" [J:45302]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Gt(ROSA)26Sor^{tm1(Cdkn1b,EGFP)Dor}/Gt(ROSA)26Sor⁺,Myl2^tm1(cre)Krc/Myl2⁺ Genetic Background: involves: 129/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
MP:0000284	double outlet right ventricle	"both the aorta and the pulmonary trunk originate from the right ventricle, usually in conjunction with a ventricular septal defect" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:67826]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000324	increased mast cell number	"greater than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000352	decreased cell proliferation	"less than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0000359	abnormal mast cell morphology	"anomalous structure of these granulated cells found in most tissues, but most abundantly in skin and g.i. tract" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000367	abnormal coat/ hair morphology	"anomalous color, structure, growth, or texture of the hair" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2J
MP:0000377	abnormal hair follicle	"malformed invagination of the epidermis from which the hair shaft develops" [J:65031]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000378	absent hair follicles	"missing epidermal invaginations from which the hair shaft develops" [J:65039]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000379	reduced hair follicle number	"fewer number of the epidermal invaginations from which the hair shaft develops" [J:15108]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000380	small hair follicles	"reduced size of the invagination of the epidermis from which the hair shaft develops" [J:56777]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000383	abnormal hair follicle orientation	"misaligned hair follicles; hair follicles that do not orient in a typical pattern" [J:47620]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0000402	abnormal zigzag hairs	"anomalies of truncal hairs that contain one air cell in the medulla" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0000414	alopecia	"absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000427	abnormal hair cycle	"aberrant growth or asynchronous timing of the hair growth " [J:65302]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000428	abnormal craniofacial morphology	"anomalous structure or development of the face and/or cranium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Id2^tm1Yyk/Id2^tm1Yyk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000432	abnormal head morphology	"anomalous structure or development of the portion of the body containing the brain and organs of sight, hearing, taste, and smell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0000435	shortened head	"reduced anterior-posterior length of the head" [J:42035]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0000438	abnormal skull morphology	"anomalous structure or development of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Id2^tm1Yyk/Id2^tm1Yyk Genetic Background: involves: 129S1/Sv * 129X1/SvJ * NMRI Allelic Composition: Fgfr2^tm1Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000440	domed skull		Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0000445	short snout	"reduced length of the anterior facial part of the muzzle" [J:53370]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000458	abnormal mandible morphology	"malformation of the lower bony framework of the mouth where the inferior teeth are held" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0000462	abnormal digestive system morphology	"anomalous structure of the system dedicated to the mechanical, chemical, and enzymatic processing of food" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Slc2a10^G128E/Slc2a10^G128E Genetic Background: C3HeB/FeJ-Slc2a10^G128E
MP:0000470	abnormal stomach morphology	"malformation of the sac-like structure of the digestive canal between the esophagus and the small intestine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000492	abnormal rectum morphology	"structural aberration in the terminal portion of the intestinal tube adjacent to the anus" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000496	abnormal small intestine morphology	"structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Foxb1^tm1Pgr/Foxb1^tm1Pgr Genetic Background: B6.129-Foxb1^tm1Pgr Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1.1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0000519	hydronephrosis	"dilation of the pelvis and calices of one or both kidneys" [J:56641]	Show Allelic Composition: Gja1^tm1.1Kwi/Gja1^tm4Kwi Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N
MP:0000520	absent kidney	"missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]	Show Allelic Composition: Cebpa^tm2Btp/Cebpa^tm2Btp Genetic Background: B6.129P2-Cebpa^tm2Btp Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0000521	abnormal kidney cortex	"anomalous structure or development of the outer area of the kidney, which contains the glomerular capillaries and the capsula glomeruli that enclose it " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0000527	abnormal kidney development	"anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N
MP:0000537	abnormal urethra morphology	"anomalous structure of the canal leading from the bladder, discharging the urine externally" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm3Lni/Fgfr2^tm3Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0000549	absent limbs	"missing extremities" [J:51966, J:50768]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm3Lni/Fgfr2^tm3Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^hob/Fgfr2^hob Genetic Background: involves: C57BL/6J Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^hob Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
MP:0000551	absent forelimb	"missing the entire anterior extremities" [MGI:tc, J:54637]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000557	absent hindlimb	"missing the entire posterior extremities" [MGI:tc, J:54637]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000566	synostosis	"osseous union of two bones that are not normally connected" [J:13049]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0000579	abnormal nail morphology	"structural or developmental anomaly of any of the thin, horny, translucent plates covering the dorsal surface of the distal end of each terminal phalanx of the digits" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0000596	abnormal liver development	"anomalous differentiation of the liver" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0000613	abnormal salivary gland morphology	"malformed saliva-secreting glands of the oral cavity" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000629	absent mammary gland	"missing milk-secreting glands of the breast" [J:18378]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0000648	absent sebaceous gland	"missing the holocrine glands of the dermis that secrete sebum into the hair follicles" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:54637]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0000649	sebaceous gland atrophy	"wasting or decreased size of holocrine glands of the dermis that secrete sebum into the hair follicles" [J:65146]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0000666	reduced number of prostate ducts	"fewer than normal minute canals that pass the prostatic secretions to the urethra" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0000703	abnormal thymus morphology	"anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0000704	abnormal thymus development	"anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Mnx1-cre)1Jrs/? Genetic Background: involves: 129X1/SvJ * C57BL/6
MP:0000762	abnormal tongue morphology	"anomalous structure or development of the mobile mass of muscular tissue and surrounding epithelial tissue occupying the cavity of the mouth and forming part of the floor" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Jun^tm1Wag/Jun^tm1Wag Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000774	reduced brain size	"smaller appearance of the brain" [J:35802]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0000780	abnormal corpus callosum morphology	"malformation or absence of a thick bundle of nerve fibers comprising a commissural plate connecting the two cerebral hemispheres; it consists of contralateral axon projections that provides communications between the right and left cerebral hemispheres" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0000785	telencephalon hypoplasia	"reduced cell number in cerebral cortex and basal ganglia" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:45302]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129 Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0001175	abnormal lung morphology	"malformed organ of respiration" [J:35802]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0001176	abnormal lung development	"malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Sftpc-cre)1Blh/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
MP:0001177	atelectasis	"collapse of the lung or any portion of the lung, or decreased or absent air in the lung, resulting in loss of lung volume " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0001178	pulmonary hypoplasia	"reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]	Show Allelic Composition: Fgfr2^hob/Fgfr2^hob Genetic Background: involves: C57BL/6J Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^hob Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
MP:0001181	absent lungs	"missing organs of respiration" [J:51966, J:50768]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0001194	dermatitis	"inflammation of the skin" [J:65146]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001199	thin skin	"reduced thickness of the outer protective layer of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001201	translucent skin	"skin that is more transparent to light than normal " [J:15108]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0001216	abnormal epidermal layer morphology	"anomalous structure or development of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001218	thin epidermis	"reduced thickness of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001219	thickened epidermis	"increase in the width of the epidermal cell layer in the skin" [J:65146]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001222	epidermal hyperplasia	"increase in size of the epidermis due to increase in epidermal cell number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:65146]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0001231	abnormal basal cell layer morphology	"structural anomaly of the deepest layer of the epidermis, which is composed of dividing stem cells and anchoring cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0001239	abnormal granular layer morphology	"structural or developmental anomaly of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001240	abnormal cornified layer morphology	"structural or developmental anomaly of the outer layer of the epidermis, consisting of several layers of flat keratinized non-nucleated cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0001244	thin dermal layer	"reduced thickness of the dermis" [J:65030]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0001258	decreased body length	"decreased crown to tail distance compared to controls" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Mnx1-cre)1Jrs/? Genetic Background: involves: 129X1/SvJ * C57BL/6 Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Swnr/Fgfr1^tm1Swnr,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001297	microphthalmia	"reduced average size of the eyes" [J:18048]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129 Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0001300	ocular hypertelorism	"increased distance between the eyes " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0001302	eyelids open at birth	"widely open eyes instead of closed at perinatal stage" [J:51966]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0001341	absent eyelids	"missing skin folds covering the front of the eyeball when closed" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001347	absent lacrimal glands	"missing the glands that secrete tears" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129X1/SvJ * FVB
MP:0001426	polydipsia	"excessive thirst that is relatively prolonged" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001533	abnormal skeleton physiology	"anomalous function of the bony framework of the body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gad1^tm1.1Tama/Gad1⁺,Pcnt^m239Asp/Pcnt^m239Asp Genetic Background: involves: C57BL/6 * C57BL/6J * CBA * FVB/N
MP:0001613	abnormal vasodilation	"anomalous widening of the lumen of the blood vessels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0001663	abnormal digestive system physiology	"altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0001669	abnormal glucose absorption	"anomalous ability of the body to take in this major monosaccharide, a 6-carbon sugar" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0001672	abnormal embryogenesis/ development	"anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Syne1^tm1Rexu/Syne1^tm1Rexu,Syne2^tm1Rexu/Syne2⁺ Genetic Background: involves: 129 * C57BL/6
MP:0001676	abnormal apical ectodermal ridge	"malformation of the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [MGI:tc]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0001677	absent apical ectodermal ridge	"missing the multilayered ectodermal region at the tip of a limb bud necessary for the proper development of the underlying mesenchyme" [J:54637]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0001685	abnormal endoderm development	"failure or abnormality in the formation of the endoderm during gastrulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1 Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Sftpc-cre)1Blh/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2 Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0001711	abnormal placenta		Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0001712	abnormal placental development	"malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1 Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^tm1.1Dor Genetic Background: involves: 129X1/SvJ
MP:0001725	abnormal umbilical cord	"malformed connective stalk between the fetus and the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0001732	postnatal growth retardation	"slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0001874	acanthosis	"diffuse hyperplasia of the spinous layer of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Swnr/Fgfr1^tm1Swnr,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001891	hydroencephaly	"excessive accumulation of cerebrospinal fluid in the brain, especially the cerebral ventricles, often leading to increased brain size and other brain trauma" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0001919	abnormal reproductive system physiology	"anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^tm2(Sp8)Lma/Gt(ROSA)26Sor⁺,Sp8^tm1Smb/Sp8^tm1Smb,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Twist2^{tm1.1(cre)Dor}/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0001922	reduced male fertility	"reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001926	female infertility	"inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0001943	abnormal respiration	"anomaly in the movement of gases into and out of the lung " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv
MP:0001953	respiratory failure	"cessation of or failure to commence breathing" [MGI:cls, J:60159]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0001954	respiratory distress	"physical difficulty or inability to breathe" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0002051	skin papilloma	"a circumscribed, benign epithelial tumor projecting from the surrounding surface" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0002058	neonatal lethality	"death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0002059	abnormal seminal gland morphology	"anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI Allelic Composition: Fgfr2^svs/Fgfr2^svs Genetic Background: either: CXB1/By or CXB1/ByEss * CXB1/ByLac
MP:0002060	abnormal skin morphology	"malformation or atypical structure of the membranous protective covering of the body" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:56777]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0002084	abnormal developmental patterning	"abnormal systematic arrangement of the developing body along an axis" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0002113	abnormal skeleton development	"anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tbx1^tm1Bem/Tbx1^tm1Bem Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0002114	abnormal axial skeleton morphology	"abnormal development of vertebral, spinal or sternal bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tbx1^tm1Bem/Tbx1^tm1Bem Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0002116	abnormal craniofacial bone morphology	"abnormal development of cranial or facial bones resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J
MP:0002152	abnormal brain morphology	"anomalous structure of or abnormal development of the brain, one of the two components of the central nervous system and the center of thought and emotion; controls coordination, bodily activities and the interpretation of information from the senses (sight, hearing, smell, etc.)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, http://cancerweb.ncl.ac.uk]	Show Allelic Composition: Casp3^tm1Flv/Casp3⁺ Genetic Background: involves: 129S1/Sv * C57BL/6J Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(GFAP-cre)25Mes/0 Genetic Background: involves: 129X1/SvJ * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Allelic Composition: Fgfr2^tm2Dsn/Fgfr2^tm2Dsn Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Fgfr2^tm2.2Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm2Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm1Wrst/Fgfr2^tm1Wrst Genetic Background: involves: C57BL/6
MP:0002182	abnormal astrocyte morphology	"anomalous structure, number or compostion of one of the large neuroglia cells of nervous tissue" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(GFAP-cre)25Mes/0 Genetic Background: involves: 129X1/SvJ * FVB/N Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(GFAP-cre)25Mes/0 Genetic Background: involves: 129X1/SvJ * FVB/N
MP:0002267	abnormal bronchiole morphology	"any structural anomaly of the conducting airway of the lungs found terminal to the bronchi. These structures contain neither cartilage nor mucous-secreting glands; the epithelium of the bronchioles becomes thinner with each branching. " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0002295	abnormal pulmonary circulation	"anomalous circulation of blood through the lungs" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002427	dwarfism	"abnormally undersized with disproportionate body parts" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Tbx1^tm1Bem/Tbx1^tm1Bem Genetic Background: involves: 129/Sv * C57BL/6J * FVB * SJL
MP:0002428	abnormal semicircular canal	"anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0002497	increased IgE	"greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0002655	abnormal keratinocyte morphology	"structural or developmental anomaly of the cells of the epidermis that produce keratin in the process of differentiating into the dead and fully keratinized cells of the stratum corneum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002663	failure to form blastocele	"developmental anomaly resulting in the absence of the cavity in the blastula of the developing embryo" [cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:19904]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0002691	small stomach	"reduced size of the stomach" [J:77398, dlb:Donna Burkart , Mouse Genome Informatics Curator]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0002740	heart hypoplasia	"decreased cell number in the heart" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:77765]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Gt(ROSA)26Sor^{tm1(Cdkn1b,EGFP)Dor}/Gt(ROSA)26Sor⁺,Myl2^tm1(cre)Krc/Myl2⁺ Genetic Background: involves: 129/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
MP:0002750	exophthalmos	"protrusion of one or both eyeballs" [J:47965, il:Ira Lu , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0002764	short tibia	" reduced length of the medial and larger bone of the lower leg" [J:12736, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0002796	impaired skin barrier function	"impaired ability of the skin to regulate water loss; frequently leads to dehydration" [J:56641]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0002835	abnormal cranial suture morphology	"defects of the fibrous joint in the bones of the head" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62161]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0002932	abnormal joint	"defect in the articulation point of two or more bones" [RGD:Rat Genome Database submission, MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0002989	small kidney	"reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0002995	primary sex reversal	"gonad type is not consistent with chromosomal sex" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^hob/Fgfr2^hob Genetic Background: involves: C57BL/6J Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^hob Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
MP:0003047	abnormal thoracic vertebrae morphology	"malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0003048	abnormal cervical vertebrae morphology	"malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0003051	curly tail	"a loop or corkscrew-like curl in the tail" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003085	abnormal egg cylinder morphology	"anomaly in the transient cup-like structure of the epiblast that consists of a single layer of embryonic cells" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0003109	short femur	"reduced length of the long bone of the thigh" [ava:Anna V. Anagnostopoulos, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003120	abnormal tracheal cartilage	"any structural anomaly of the cartilaginous structures that support the trachea" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:97123]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm2Schl/Fgfr2^tm2Schl Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6
MP:0003124	hypospadia	"a urethral opening located closer to the base of the penis and not at the tip" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003140	dilated atria	"an expansion in the volume of one or both of the upper chambers of the heart" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0003189	fused joints		Show Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv
MP:0003231	abnormal placental vasculature	"malformation in the vessels of the placenta" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0003308	abnormal cochlear sensory epithelium		Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0003315	abnormal perineum morphology	"malformation in the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0003403	absent placental labyrinth	"malformed structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:73417]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0003409	decreased width of hypertrophic chondrocyte zone	"decreased width of cartilage cell matrix layer " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0003414	epidermal cyst	"a cyst formed of a mass of epidermal cells which is present beneath the epidermis; the wall is lined with stratified squamous epithelium and exhibits increased/abnormal keratinization" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0003420	delayed intramembranous bone ossification	"late onset of bone formation in bones that form without a cartilagenous intermediate including the cranium and clavicle" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:94631]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003427	parakeratosis	"abnormal retention of the nuclei of the keratinocytes in the stratum corneum of the epidermis" [smb:Susan M Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0003641	small lung	"reduced size of the lung relative to normal" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:95332]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0003662	abnormal proliferative zone	"germinal layer of the epiphyseal plate where cells are actively dividing as well as producing extracellular matrix" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96254]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0003703	abnormal vestibulocochlear ganglion morphology	"malformed group of neuron cell bodies associated with the eighth cranial nerve during embryogenesis; splits in later development to form the cochlear and vestibular ganglia" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0003704	abnormal hair follicle development	"anomalous development of the epidermis from which the hair shaft develops " [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0003743	abnormal facial morphology	"anomalous structure or development of the face" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0003755	abnormal palate	"anomaly in the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate) " [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Jun^tm1Wag/Jun^tm1Wag Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003760	short palate	"abnormally decreased length to the roof of the oral cavity" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Jun^tm1Wag/Jun^tm1Wag Genetic Background: involves: 129S2/SvPas * C57BL/6 Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003816	abnormal pituitary gland development	"malformation or incomplete differentiation of the compound gland suspended from the base of the hypothalamus, which secretes somatotropins, prolactin, TSH (thyroid-stimulating hormone), gonadotropins, adrenal corticotropin" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:51160]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0003840	abnormal coronal suture morphology	"malformation of the articulation between the parietal bones and the frontal bone" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003841	abnormal lambdoidal suture morphology	"malformation of the articulation of the parietal bones and the occipital bone" [Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003843	abnormal sagittal suture morphology	"malformation of the articulation between the parietal bones" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0003845	abnormal decidualization	"disrupted proliferation, differentiation or transformation of endometrial stromal cells into decidual cells in the maternal uterus following embryo implantation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:43609, J:48920]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0003853	dry skin	"skin characterized by the lack of natural or normal moisture" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0003934	abnormal pancreas development	"anomaly in the formation of the organ that secretes pancreatic juice into the duodenum and secretes glucagon and insulin into the bloodstream" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0003938	abnormal ear development	"developmental anomaly of any of the structures involved in the ear or vestibular system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0004032	abnormal interventricular groove	"malformation of the intendation dividing the two ventricles, comprised of the sulcus interventricularis anterior and the sulcus interventricularis posterior" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004055	atrial hypoplasia	"reduction in cell number of one or both of the two upper chambers of the heart" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:36567]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004067	abnormal ventricular trabeculae morphology	"aberrant structure of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004200	reduced fetal size	"smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^hob Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/N
MP:0004247	small pancreas	"decrease of the size of the pancreas compared to controls" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004255	abnormal spongiotrophoblast layer morphology	"anomaly in the structure of the outer structural layer of the rodent placenta" [PMID:11433360]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0004276	abnormal medial ganglionic eminence morphology	"any structural anomaly of a distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the neocortex; however, hippocampal neurons, thalamus, septum and olfactory bulb neurons are also partly derived from the MGE" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0004277	abnormal lateral ganglionic eminence morphology	"any structural anomaly of a distinct elevation of a transient proliferating cell mass of the fetal subventricular zone; this mass contributes most of its cells to the striatum; however, neocortex, thalamus, septum and olfactory bulb neurons are also partly derived from the LGE" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:12637172]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0004310	small otic vesicle	"reduced size of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0004320	split sternum	"the appearance of an abnormal division in the long flat bone of the chest which articulates with clavicle and first seven rib pairs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004322	abnormal sternebra morphology	"any structural anomaly of one segments of the primordial sternum of the embryo; these segments fuse to form the body of the adult vertebrate sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0004343	small scapula	"reduced size of either or both of the large, flat bones of the back part of the shoulder" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0004346	absent acromion	"missing the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0004351	short humerus	"reduced length of one or both of the bones of the forelimb that articulates with the scapula above and the radius and ulna below" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0004355	short radius	"reduced length of the short bone of the lateral forearm" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0004377	small frontal bone	"reduced size of the bone forming the forehead and roof of the eye orbit" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004418	small parietal bone	"reduced size of the curved bone forming part of the vault of the cranium" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004448	abnormal presphenoid bone morphology	"any structural anomaly of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0004449	absent presphenoid bone	"absence of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004451	short presphenoid bone	"reduced length of the anterior part of the body of the sphenoid bone in front of the basisphenoid; it is usually a separate bone in the young or fetus, but becomes a part of the sphenoid in the adult" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0004469	abnormal zygomatic arch morphology	"any structural anomaly of the bony arch in vertebrates that extends along the side or front of the skull beneath the eye socket and is formed by the temporal process of the zygomatic bone and the zygomatic process of the temporal bone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0004471	short nasal bone	"reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0004499	increased incidence of chemically-induced tumors	"higher than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0004505	decreased renal glomerulus number	"reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N
MP:0004507	abnormal ischium morphology	"any structural anomaly of the lowest of the three major bones that constitute each half of the pelvis, distinct at birth but later becoming fused with the ilium and pubis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0004509	abnormal pelvic girdle bone morphology	"any structural anomaly of the bones of the pelvis by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004537	abnormal palatine shelf	"any structural anomaly of the palatine bone; normally fuses with maxillary shelf to form secondary (hard) palate" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004552	fused tracheal cartilage rings	"fusion of the 16-20 incomplete rings of hyaline cartilage that form the skeleton of the trachea" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0004556	enlarged allantois	"increased size of the fetal membrane which contributes to the formation of the umbilical cord and placental blood vessels" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0004573	absent limb buds	"missing the mesenchymal outgrowth on the lateral trunk of the embryo that develops into the limbs" [MESH:National Library of Medicine_Medical Subject Headings]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^tm1.1Dor Genetic Background: involves: 129X1/SvJ
MP:0004592	small mandible	"reduced size of the lower bony framework of the mouth where the inferior teeth are held" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0004596	abnormal mandibular angle morphology	"any structural anomaly of the portion of the mandible where the body of the mandible (horizontal portion) and the rami (perpendicular portions) meet; these normally unite nearly at right angles" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0004606	absent vertebral spinous process	"missing the dorsal projection of the vertebral arch that projects backward and downward from the junction of the laminae, and serves for the attachment of muscles and ligaments" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0004609	vertebral fusion	"the union of one or more vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004619	caudal vertebral fusion	"the union of one or more caudal vertebrae into a single structure in species where this does not normally occur" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0004620	cervical vertebral fusion	"the union of one or more cervical vertebrae into a single structure" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004678	split xiphoid process	"the appearance of an abnormal division of the posterior tip of the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0004691	absent pubic bone	"absence of the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0004726	abnormal nasal capsule morphology	"any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004792	abnormal synaptic vesicle number	"anomaly in the number of the small, membrane bound sacs that contain various neurotransmitter molecules that are concentrated at pre-synaptic membranes and release the neurotransmitters by fusion of these vesicles with the presynaptic membrane, followed by exocytosis of their contents" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cdkn2a^tm2.1Brn/Cdkn2a^tm2.1Brn Genetic Background: involves: 129P2/OlaHsd * FVB/N
MP:0004793	abnormal synaptic vesicle clustering	"any functional anomaly in the process of accumulation of synaptic vesicles at the active zone of presynaptic membranes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cdkn2a^tm2.1Brn/Cdkn2a^tm2.1Brn Genetic Background: involves: 129P2/OlaHsd * FVB/N Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Mnx1-cre)1Jrs/? Genetic Background: involves: 129X1/SvJ * C57BL/6 Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Lamb2^tm1Jrs/Lamb2^tm1Jrs,Tg(Mnx1-cre)1Jrs/? Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004831	long incisors	"increased length of the long pointed teeth; most anterior and prominent in the jaw" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0004841	abnormal small intestine crypts of Lieberkuhn morphology	"any structural anomaly in the tubular intestinal glands found in the mucosal membranes of the small intestine" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1.1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
MP:0004936	abnormal ureteric bud branching morphogenesis	"partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0004947	skin inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in the skin" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0004961	increased prostate weight	"greater than average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0004965	inner cell mass degeneration		Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0004985	decreased osteoclast cell number	"reduced number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0004988	increased osteoblast cell number	"greater than average number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified
MP:0004989	decreased osteoblast cell number	"reduction in the number of the bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0005006	abnormal osteoblast function	"anomalous function of this bone-forming cell, which normally forms an osseous matrix in which it becomes enclosed as an osteocyte " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0005031	abnormal trophoblast	"malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Hand1^tm1Jcc/Hand1⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0005225	abnormal vertebrae development	"anomalous formation of the vertebrae from the sclerotome" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0005238	increased brain size	"larger than the normal physical proportions of the brain" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:57958]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0005249	abnormal palatine bone morphology	"structural anomaly of the anteriorly located rigid section of the palate" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0005270	abnormal zygomatic bone morphology	"anomalous structure of the bone that forms the prominence of the cheek" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0005294	abnormal heart ventricle morphology	"structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0005298	abnormal clavicle morphology	"malformation of the doubly curved long bone that forms part of the shoulder girdle and articulates with the sternum and the scapula" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0005314	absent thyroid gland	" missing endocrine gland that is normally located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:30559]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0005352	small skull	"less than the normal size of the cranium" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0005354	abnormal ilium morphology	"structural anomaly of the broad, flaring portion of the hip bone, which is distinct at birth, but later fuses with the ischium and the pubis " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:47316]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0006011	abnormal endolymphatic duct morphology	"any structural alteration in the small membranous canal, connecting with both saccule and utricle of the membranous labyrinth, passing through the aqueduct of vestibule, and terminating in the endolymphatic sac." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0006027	impaired alveologenesis	"a block or reduction in the generation of alveoli" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:85546]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0006030	abnormal otic vesicle formation	"anomalous formation of the simple epithelial sac formed from the otic placode that gives rise to the structures of the inner ear" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313:]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0006032	abnormal ureteric bud morphology	"anomaly in the formation or development of the ureteric bud that with the metanephric mesenchyme gives rise to the kidneys " [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313:]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1⁺,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Hoxb7-cre)5526Cmb/0 Genetic Background: involves: FVB/N Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0006208	embryonic lethality throughout fetal growth and development	"death anytime after the completion of organogenesis but before E18.5 (E14 to less than E18.5)" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^hob/Fgfr2^hob Genetic Background: involves: C57BL/6J
MP:0006213	shallow orbits	"decrease in the depth of the orbit" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0006279	abnormal limb development	"anomaly in the formation of the limbs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0006287	inner ear cysts	"abnormal membranous sacs in any component of the labyrinth, including the semicircular canals, vestibule and cochlea" [J:111415, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0006288	small otic capsule	"reduced size of the cartilage or bony capsule surrounding the inner ear mechanism" [J:59285, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0006400	decreased molar number	"reduction in the number of the most posterior teeth located on either side of the jaw, and characterized by a large crown and broad chewing surface" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified
MP:0008271	abnormal bone ossification	"any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0008272	abnormal endochondral bone ossification	"anomaly in the process of the formation of bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0008277	abnormal sternum ossification	"anomaly in the process of the formation of the sternum bone by the replacement of cartilage tissue with mineralized bone" [GO:0001958, MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0008320	absent adenohypophysis	"absence of the anterior part of the pituitary that secretes a variety of hormones" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0008346	increased gamma-delta T cell number	"greater number of immature or mature T cells expressing an gamma-delta T cell receptor complex" [CL:0000798, ISBN:0781735149]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0008395	abnormal osteoblast differentiation	"atypical production of or inability to produce bone-forming cells, which normally form an osseous matrix (osteoid) in which they become enclosed as an osteocytes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0008396	abnormal osteoclast differentiation	"atypical production of or inability to produce bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ
MP:0008489	postnatal slow weight gain	"the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0008499	increased IgG1 level	"greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0008500	increased IgG2a level	"greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0008525	decreased skull height	"decrease in the distance between the cranial base and the upper domelike portion of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0008534	enlarged fourth ventricle	"increased size of the irregularly shaped cavity in the rhombencephalon, between the medulla oblongata, the pons, and the isthmus in front, and the cerebellum behind; it is continuous with the central canal of the cord below and with the cerebral aqueduct above, and through its lateral and median apertures it communicates with the subarachnoid space" [MESH:A08.186.211.276.500, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0008535	enlarged lateral ventricles	"increased size of the cavity in each of the cerebral hemispheres derived from the cavity of the embryonic neural tube; they are separated from each other by the septum pellucidum, and each communicates with the third ventricle by the foramen of Monro, through which also the choroid plexuses of the lateral ventricles become continuous with that of the third ventricle" [MESH:A08.186.211.276.650, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0008540	abnormal cerebrum morphology	"any structural anomaly of the largest part of the brain, derived from the telencephalon, and is composed of a right and a left hemisphere each which contains an outer cerebral cortex and a subcortical basal ganglia; cerebral functions include sensorimotor, emotional, and intellectual activities" [MESH:A08.186.211.730.885.287]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
MP:0008721	abnormal chemokine level	"deviation from the normal levels of any of the class of pro-inflammatory cytokines that attract and activate leukocytes" [MESH:D12.644.276.374.200]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0008785	abnormal sternal manubrium morphology	"any structural anomaly in the cranial most segment of the sternum" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0008797	facial cleft	"a cleft resulting from incomplete merging or fusion of any of the embryonic facial processes that normally unite to form the face" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mesp1^tm2(cre)Ysa/Mesp1⁺,Tg(CAG-Bgeo,-Spry2,-ALPP)1Mrt/0 Genetic Background: Not Specified
MP:0009003	abnormal vibrissa number	"any anomaly in the number of the stiff hairs projecting from the face around the nose of most mammals which act as touch receptors" [MESH:A13.950, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0009004	progressive hair loss	"thinning of hair (coat) over time, usually in a defined pattern, until entirely gone with no recurrent growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Swnr/Fgfr1^tm1Swnr,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0009050	dilated proximal convoluted tubules	"stretched or widened aperture of the luminal space of the convoluted portion of the duct system of the nephron that extends from the renal glomerular capsule in the kidney cortex into the kidney medulla where it joins the loop of Henle" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0009051	dilated distal convoluted tubules	"stretched or widened aperture of the luminal space of the convoluted portion of the duct system of the nephron between the ascending portion of the loop of Henle and the collecting duct system in the kidney cortex" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0009247	meteorism	"swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0009250	abnormal appendicular skeleton morphology	"any structural anomaly of the bones of the limbs, shoulder and pelvic girdles" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1.1Dor,Twist2^tm1(cre)Dor/Twist2⁺ Genetic Background: involves: 129X1/SvJ Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified
MP:0009397	increased trophoblast giant cell number	"greater than normal number of cells of the extraembryonic cell layer that contributes to the placenta" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0009479	abnormal cecum development	"malformation or aberrant differentiation of the large sac at the ileum and large intestine junction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0009509	absent rectum	"absence or loss of the terminal portion of the intestinal tube adjacent to the anus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0009510	cecal atresia	"congenital blockage or absence of the lumen of the cecum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0009520	decreased submandibular gland size	"reduced size of either of the large major salivary glands situated beneath the mandible" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cer1^tm1Bhr/Cer1^tm1Bhr,Lefty1^tm1Sla/Lefty1^tm1Sla Genetic Background: involves: 129S7/SvEvBrd * CD-1
MP:0009522	submandibular gland hypoplasia	"underdevelopment or reduced size of either of the large major salivary glands situated beneath the mandible, usually due to reduced cell number" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgfr2^tm2Dsn/Fgfr2⁺,Tg(Pgk1-cre)1Lni/0 Genetic Background: involves: 129 * 129X1/SvJ * BALB/c * C57BL/6
MP:0009524	absent submandibular gland	"absence of either of the large major salivary glands situated beneath the mandible" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0009525	abnormal submandibular duct morphology	"any strucutral anomaly of the duct of the submadibular gland that opens at the sublingual papilla near the frenulum of the tongue" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2⁺ Genetic Background: involves: 129P2/OlaHsd * C57BL/6 Allelic Composition: Fgf10^tm1Wss/Fgf10⁺,Fgfr2^tm2Dsn/Fgfr2⁺,Tg(Pgk1-cre)1Lni/0 Genetic Background: involves: 129 * 129X1/SvJ * BALB/c * C57BL/6
MP:0009545	abnormal dermis papillary layer	"any structural anomaly of the more superficial, thin layer of the dermis that interdigitates with the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0009570	abnormal right lung morphology	"any structural anomaly of the organ of respiration located on the right side of the body" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0009583	increased keratinocyte proliferation	"increase in the expansion rate of keratinocytes by cell division" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0009601	epidermis stratum granulosum hyperplasia	"overdevelopment or increased size, usually due an increased number of cells, of the layer of flattened cells containing basophilic granules of keratohyalin and lying just above the stratum spinosum (spiny layer) of the epidermis" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0009611	epidermis stratum spinosum hyperplasia	"overdevelopment or increased size, usually due an increased number of cells, of the layer of polyhedral cells in the epidermis; shrinkage and adhesion of these cells gives a spiny or prickly appearance" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0009653	abnormal palate development	"abnormal formation of the roof of the mouth in vertebrates formed anteriorly by a bony projection of the upper jaw (hard palate) and posteriorly by the fold of connective tissue (soft palate)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0009655	abnormal secondary palate development	"any anomaly in the formation of the part of the palate that is formed during embryonic development when palatal projections from the inner part of the maxillary processes emerge, extend and elevate into a horizontal position above the tongue" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:16942766]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0009657	failure of chorioallantoic fusion	"failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0009674	decreased birth weight	"reduction in average weight at birth compared to controls" [RGD:cur "Rat Genome Database submission"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0009703	decreased birth body size	"reduction in average body size at birth compared to controls" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0009736	abnormal prostate gland branching morphogenesis	"anomaly of the prostatic bud to repeatedly divide into lobules during development of the prostate gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0009884	palatal shelf fusion with tongue or mandible	"palatal shelves do not elevate during development and instead fuse with tongue tissues or with the mandible tissues" [PMID:16680722]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0009887	abnormal palatal shelf fusion at midline	"any anomaly in the process in which the palatal shelves grow toward the midline and adhere along the medial edge epithelia, forming the midline epithelial seam which disappears in later stages" [PMID:16942766]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0009888	palatal shelves fail to meet at midline	"polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]	Show Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm2Schl/Fgfr2^tm2Schl Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6
MP:0009890	cleft secondary palate	"congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0009931	abnormal skin appearance	"skin that looks different from the usual state" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0009932	skin fibrosis	"invasion of fibrous connective tissue into the skin, often resulting from inflammation or injury" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0010029	abnormal basicranium morphology	"any structural anomaly of the sloping floor of the cranial cavity that is comprised of parts of the ethmoidal, occipital and sphenoid bones" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0010418	perimembraneous ventricular septal defect	"abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010420	muscular ventricular septal defect	"abnormal communications between the two lower chambers of the heart, involving the muscular septum and often occurring as multiple communications, and includes central muscular or midmuscular, apical, or marginal communications when the defect is along the RV-septal junction; any single defect observed from the LV aspect may have several openings on the RV aspect" [http://emedicine.medscape.com]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010454	abnormal truncus arteriosis septation	"anomaly in the process of dividing the common arterial trunk arising out of both heart ventricles to divide into the aorta and pulmonary artery during development" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010521	absent pulmonary artery	"absence of the artery that arises from the right ventricle and conveys unaerated blood to the lungs" [MESH:A07.231.114.715]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010566	abnormal left posterior bundle morphology	"any structural anomaly of the left branch of the atrioventricular bundle that separates at the bundle of His, descends the septal wall of the left ventricle and connects to the terminal Purkinje fiber" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010585	abnormal conotruncal ridge morphology	"any structural anomaly of the pair of spiral mesenchymal swellings in the primordial ventricular outflow tract, that eventually fuse to form the conotruncal septum, dividing the subvalvular outflow tract and contributing to the membranous interventricular septum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:8823298]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010587	conotruncal ridge hypoplasia	"underdevelopment or reduced size of the pair of spiral mesenchymal swellings in the primordial ventricular outflow tract, that eventually fuse to form the conotruncal septum, dividing the subvalvular outflow tract and contributing to the membranous interventricular septum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:8823298]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010646	absent pulmonary vein	"absence of the veins that return oxygenated blood from the lungs to the left atrium of the heart" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0010678	abnormal skin adnexa morphology	"any structural anomaly of the tissue or structures associated with or embedded in the skin such as hair and hair follicles, sweat glands, sebaceous glands and claws or nails" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J Allelic Composition: Fgfr1^tm1Swnr/Fgfr1^tm1Swnr,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129S7/SvEvBrd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0010743	delayed suture closure	"late onset of the fusion of the bones of the skull" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0010911	abnormal pulmonary acinus morphology	"any structural anomaly of the part of the airway consisting of a respiratory bronchiole and all of its branches" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0010979	small ureteric bud	"reduced size of the epithelial swelling on the Wolffian duct that elongates to invade the adjacent metanephric mesenchyme" [PMID:19828308]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0010980	ectopic ureteric bud	"ureteric bud(s) are not located in the normal or expected position" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0010982	abnormal ureteric bud elongation	"any anomaly in the process in which a ureteric bud grows along its axis" [GO:0060677]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0010983	abnormal ureteric bud invasion	"any anomaly in the process in which the ureteric bud grows into the metanephric mesenchyme, and contributes to the formation of the metanephros" [PMID:19828308]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0010984	abnormal metanephric mesenchyme morphology	"any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0010994	aerophagia	"excessive swallowing of air or gas" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0010998	pulmonary alveolar proteinosis	"abnormal intra-alveolar accumulation of an amorphous, largely cell-free, surfactant-like lipoproteinaceous material that is not easily cleared from the lungs" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0011011	impaired lung lobe morphogenesis	"failure to form any of the anatomically and functionally distinct subunits (lobes) comprising the left or right lung" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0011013	bronchiolectasis	"a chronic inflammatory or degenerative condition marked by permanent dilatation (widening) of one or more bronchioles and loss of elasticity of the bronchiolar walls" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0011026	impaired branching involved in trachea morphogenesis		Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0011028	impaired branching involved in bronchus morphogenesis		Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Sftpc-cre)1Blh/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
MP:0011085	complete postnatal lethality	"premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0011087	complete neonatal lethality	"death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm1Schl/Fgfr2^tm1Schl Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 Allelic Composition: Fgfr2^tm2.1Lni/Fgfr2^tm2.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0011096	complete embryonic lethality before somite formation	"death of all organisms of a given genotype in a population between the point of implantation and somite formation (Mus: E4.5 to less than E8)" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Allelic Composition: Fgfr2^tm1.1Wrst/Fgfr2^tm1.1Wrst Genetic Background: involves: BALB/c * C57BL/6
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss) Allelic Composition: Fgfr2^tm1.1Dor/Fgfr2^tm1.1Dor Genetic Background: involves: 129X1/SvJ
MP:0011158	absent hypodermis muscle layer	"absence of the skeletal muscle layer in the superficial fascia" [ISBN:0-683-40008-8]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0011185	absent primitive endoderm	"absence of the monolayer of cells derived from and located on the surface of inner cell mass, directly facing the blastocoele, and is separated from the more centrally located epiblast by basal lamina; the primitive endoderm give rises to the visceral endoderm and the parietal endoderm" [PMID:21123814]	Show Allelic Composition: Fgfr2^tm1Cxd/Fgfr2^tm1Cxd Genetic Background: either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * NIH Black Swiss)
MP:0011290	decreased nephron number	"reduction in the total number of filtering units of the kidney" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0011368	increased kidney apoptosis	"increase in the number of cells of the kidney undergoing programmed cell death" [MGI:anna]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0011386	increased metanephric mesenchyme apoptosis	"increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion" [MGI:anna]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * FVB/N * SJL
MP:0011387	absent metanephric mesenchyme	"absence of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, that gives rise to the developing metanephros; normally, interactions between the ureteric bud and the metanephric mesenchyme lead to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:anna]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0011441	decreased kidney cell proliferation	"decrease in the expansion rate of any kidney cell population by cell division" [MGI:anna]	Show Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax3-cre)1Joe/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
MP:0011485	abnormal urethra urothelium morphology	"any structural anomaly of the epithelial lining of the luminal space of the urethra" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^tm2(Sp8)Lma/Gt(ROSA)26Sor⁺,Sp8^tm1Smb/Sp8^tm1Smb,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA
MP:0011495	abnormal head shape	"any anomaly in the characteristic surface outline or contour of a head of an organism" [MGI:csmith]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0011627	decreased skin pigmentation	"visually detectable dilution of pigment present in the skin" [MGI:csmith]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0011696	absent mast cells	"any structural anomaly of a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation; progenitors leave bone marrow and mature in connective and mucosal tissue; mature mast cells are found in all tissues, except the bloodstream." [CL:0000097]	Show Allelic Composition: Cpa3^tm3(icre)Hrr/Cpa3⁺,Fgfr1^tm1Upir/Fgfr1^tm1Upir,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * C57BL/6J * DBA/2J
MP:0011710	increased osteoblast differentiation		Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0011759	absent Rathke s pouch	"absence of the diverticulum arsing from the embryonic buccal cavity from which the anterior lobe of the pituitary gland is developed" [MGI:anna]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0011772	genital tubercle hypoplasia	"underdevelopment or reduced size of the embryonic anlage of the external genitalia, usually due to a reduced number of cells" [MGI:anna]	Show Allelic Composition: Gt(ROSA)26Sor^tm2(Sp8)Lma/Gt(ROSA)26Sor⁺,Sp8^tm1Smb/Sp8^tm1Smb,Tg(Msx2-cre)5Rem/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * CBA Allelic Composition: Fgfr1^tm1Jpa/Fgfr1^tm1Jpa,Fgfr2^tm1Dor/Fgfr2^tm1Dor,Twist2^{tm1.1(cre)Dor}/Twist2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ
MP:0011861	increased cranium height	"increase in the rostral-caudal distance between the cranial base and the upper domelike portion of the skull" [MGI:mnk]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0011862	decreased cranium length	"having an decreased dorsal-to-ventral distance of the cranium" [MGI:mnk]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0012085	midface hypoplasia	"underdevelopment of the midfacial region comprising the nasal, maxillary, and zygomatic bones, leading to a concave-looking face" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0012556	increased cell death	"increased occurrence of the cessation of function at the cellular level" [http://orcid.org/0000-0001-5208-3432]	Show Allelic Composition: Foxg1^tm1(cre)Skm/Foxg1⁺,Frs2^tm1Fwan/Frs2^tm1Fwan,Frs3^tm1Jheb/Frs3^tm1Jheb Genetic Background: involves: 129 * Swiss Webster
MP:0012667	split sternal manubrium	"the appearance of an abnormal division of the cranial most segment of the sternum" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0012683	absent telencephalon	"absence of the enlarged anteriolateral part of the brain; consists of the paired cerebral hemispheres and olfactory bulbs, the basal ganglia and the connecting structures" [MGI:anna]	Show Allelic Composition: Foxg1^tm1(cre)Skm/Foxg1⁺,Frs2^tm1Fwan/Frs2^tm1Fwan,Frs3^tm1Jheb/Frs3^tm1Jheb Genetic Background: involves: 129 * Swiss Webster Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Fgfr3^tm6.1Cxd/Fgfr3^tm6.1Cxd,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0013192	decreased sebaceous gland number	"fewer than normal numbers of the holocrine glands that secrete sebum into the hair follicles, or in hairless areas into ducts" [MGI:anna]	Show Allelic Composition: Fgfr1^tm1Upir/Fgfr1^tm1Upir,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: C57BL/6 * C57BL/6J * DBA/2J
MP:0013264	tongue ankylosis	"partial or complete fusion or adherence of the tongue to the floor of the mouth, resulting in varying degrees of restricted tongue mobility; partial ankyloglossia (aka tongue-tie) is caused by a lingual frenulum that is abnormally short or is attached too close to the tip of the tongue; in complete ankyloglossia the tongue is tethered to the floor of the mouth" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0013310	abnormal adrenal gland development	"aberrant formation or incomplete differentiation of the pair of endocrine glands located above the kidney that are responsible for steroid hormone secretion from the cortex and neurotransmitter (such as epinephrine and norepinephrine) secretion from the medulla" [MGI:anna]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0013317	abnormal seminal vesicle development	"aberrant or incomplete differentiation of either of the paired sac-like glandular structures situated posterolateral to the urinary bladder in the male and functioning as part of the reproductive system; seminal vesicles develop from the segments of the Wolffian ducts immediately adjacent to the urogenital sinus" [MGI:Anna]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0013318	abnormal branching involved in seminal vesicle morphogenesis	" anomaly in the process in which the seminal vesicle is generated and organized in many mammals including mice and humans; in mice, the initial seminal vesicle buds form cane-shaped tubes off of the Wolffian ducts before birth; after birth, the initial tubes develop lateral branches that elongate and often undergo secondary branching morphogenesis; branching morphogenesis is largely complete by 2 weeks of age" [MGI:Anna, PMID:16916376]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0013331	abnormal lacrimal gland development	"aberrant formation or incomplete differentiation of the paired almond-shaped glands, one for each eye, that secrete the aqueous layer of the tear film; each lacrimal gland develops through branching morphogenesis regulated by FGF signaling; at E12.5, the conjunctival epithelium at the temporal side of the mouse eyes invades the Fgf10-expressing mesenchyme to form the initial lacrimal gland bud; the bud elongates posteriorly until E15.5 when secondary branching begins to establish the complex tubuloalveolar structure; this eventually gives rise to the mature lacrimal gland composed of numerous ducts, acini and connective tissue" [MGI:Anna, PMID:22745308]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129X1/SvJ * FVB
MP:0013351	abnormal Rathke s pouch development	"any anomaly in the formation of the pouch of ectoderm which grows out from the upper surface of the embryonic stomodeum and gives rise to the anterior and intermediate lobes of the pituitary gland" [MGI:Anna]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0013352	abnormal Rathke s pouch apoptosis	"any change in the timing or number of Rathke s pouch cells undergoing programmed cell death" [MGI:Anna]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0013470	absent lacrimal gland bud	"absence of the single bud-like invagination of the conjunctival fornix epithelium at the temporal aspect of the eye that signals lacrimal gland formation; in mouse, the primary bud arises around E13.5 and extends caudally into the surrounding neural-crest derived periocular mesenchyme at E14.5" [MGI:Anna]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Tg(Pax6-cre,GFP)1Pgr/0 Genetic Background: involves: 129X1/SvJ * FVB
MP:0013578	abnormal stomach glandular region morphology	"any structural anomaly of the distinct glandular stomach area which in rodents is demarcated from the non-glandular forestomach by the limiting ridge (margo plicatus); the glandular stomach is connected to the small intestine (duodenum); the wall of the glandular stomach consists of, from inside to outside, simple columnar epithelium containing gastric glands, the lamina propria (epithelium and lamina propria form the glandular mucosa), the muscularis mucosae, the submucosa, the muscularis interna and externa (inner circular and outer longitudinal layers of smooth muscle), and the serosa; the gastric glands lined by simple columnar epithelium form deep gastric pits (foveolae) that are perpendicular to the wall of the stomach; three types of gastric glands exist; the cardiac glands, located near the limiting ridge, contain mucous cells; the pyloric glands also contain mucous cells; the fundic glands, which make up the majority of the gastric glands, contain a variety of cells: mucous neck cells, small, basophilic chief cells, and large, round parietal cells with a granular eosinophilic cytoplasm" [http://ctrgenpath.net/static/atlas/mousehistology/Windows/digestive/glandular.html, MGI:Anna]	Show Allelic Composition: Fgfr2^tm3Dsn/Fgfr2^tm3Dsn Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0013580	abnormal nasal gland morphology	"any structural anomaly of any of the seromucous glands found in the respiratory region of the nasal mucous membrane, including anterior serous glands, seromucous glands, and Bowman glands" [http://en.wikipedia.org/wiki/Nasal_glands, MGI:Anna, UBERON:0012278]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0013582	abnormal lateral nasal gland morphology	"any structural anomaly of the lateral nasal glands (the largest nasal secretory glands in rodents) which surround the maxillary sinus located in the lateral wall adjacent to each nasal passage and are characterized by cytologic features similar to those described for the major serous salivary glands; secretory contents of the LNG drain into the nasal vestibule; the LNG is a major site for the synthesis and secretion of odorant-binding proteins that serve as odorant carriers in nasal mucus; it also, synthesizes large amounts of immunoglobulin A, which is important for immune defense of the upper respiratory tract, and testosterone and salivary androgen-binding proteins, which are likely important in olfaction and reproductive behavior" [ISBN:0080454321, ISBN:0123813611, MGI:Anna]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0013721	abnormal mammary placode morphology	"any structural anomaly of the transient lens-shaped thickening of surface ectoderm that will give rise to the mammary bud proper; in mouse, five pairs of symmetrically positioned mammary placodes (three thoracic and two inguinal) form at reproducible locations along the mammary line at E11.5; the individual pairs develop asynchronously and in a distinct order; pair 3 is first, followed by pair 4, then by pairs 1 and 5 (which develop together), and finally by pair 2; the orientation of placodal cells is not uniform, suggesting that placodes are formed by migration of cells from the mammary line; between E11.5 and E12.5, each mammary placode expands and invaginates into the underlying mesenchyme to form an early bulb-shaped mammary bud " [PMID:16168142, PMID:20484386]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0013766	absent palatal rugae	"absence of the transverse folds (ridges) of the mucosa located on the anterior third part of the secondary (hard) palate of most mammalian species" [MGI:Anna, PMID:19087265]	Show Allelic Composition: Fgfr2^tm1.1Dsn/Fgfr2^tm1.1Dsn Genetic Background: involves: 129P2/OlaHsd
MP:0013785	abnormal mammary gland bud morphology	"any structural anomaly of the morphologically distinct bulb of epithelial cells formed once each mammary placode expands and invaginates into the underlying mesenchyme; in mouse embryos at E12.5, each epithelial bud with its contiguous mesenchyme is elevated above the surrounding ectoderm as a knob or dome; at E13.5, the buds sink into the underlying dermal mesenchyme, and by E14.5 they can no longer be detected externally; in female mouse embryos, five pairs of anlagen or buds are formed along the mammary line between E12.5 and E14.5 by proliferation of basal epidermal cells; while further mammary development is temporarily arrested in females, androgen receptor activation in male embryos causes degeneration of the buds between E13.5 and E15.5; in female mice, further development is resumed at around E15.5 when each bud elongates to form a mammary cord (sprout), invading the underlying fat pad precursor" [http://www.informatics.jax.org/greenbook/frames/frame13.shtml, MGI:Anna, PMID:12558599]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N
MP:0013904	abnormal seminal vesicle muscle layer morphology	"any structural anomaly of the thick muscular layer of the seminal vesicle consisting of an inner circular and outer longitudinal layer of smooth muscle which contracts during the emission phase of ejaculation to expel seminal vesicle fluid into the prostatic urethra" [MGI:Anna]	Show Allelic Composition: Dbt^tm1Geh/Dbt^tm1Geh,Tg(tetO-DBT)525AGeh/0,Tg(Cebpb-tTA)5Bjd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB * NMRI
MP:0014051	abnormal maxillary-premaxillary suture morphology	"any structural anomaly of the line of union of the two portions of the maxilla (pre- and postmaxilla)" [ISBN:0683400088]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0014152	absent exorbital lacrimal gland	"absence of the large extra-orbital lacrimal gland that, in mice, is normally located subcutaneously at the anteroventral base of the ear adjacent to the parotid gland" [MGI:Anna]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N
MP:0020386	adipose tissue inflammation	"local accumulation of fluid, plasma proteins, and leukocytes in adipose tissue" [MGI:anna, PMID:24662293, PMID:24695736, PMID:26629401]	Show Allelic Composition: Fgfr2^tm1Dsn/Fgfr2^tm1Dsn,Tg(KRT5-cre)5132Jlj/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * DBA/2J
MP:0030029	wide cranial sutures	"an abnormally increased width of one or more cranial sutures for age-related norms, generally resulting from delayed suture closure" [HP:0010537]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0030064	small face	"presence of an abnormally small face" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030066	short face	"an abnormally decreased height (length) of the face" [MGI:anna]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv
MP:0030167	decreased inner canthal distance	"decreased distance between the inner corners (medial canthi) of the eyes where the eyelids meet" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0030194	abnormal intermaxillary suture morphology	"any structural anomaly of the anterior median suture between the two maxillae of the upper jawbone, located between the inferior border of the nasal aperture and the central incisor teeth; it usually ossifies later in life and becomes a synostosis" [http://www.anatomyexpert.com/app/structure/1673/43/, MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0030196	abnormal nasomaxillary suture morphology	"any structural anomaly of the cranial suture found between the nasal bone and the frontal process of the maxilla" [https://www.imaios.com/en/e-Anatomy/Anatomical-Parts/Nasomaxillary-suture, MGI:anna]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0030200	abnormal nasal septum cartilage morphology	"any structural anomaly of the hyaline cartilage of the nasal septum that is somewhat quadrilateral in shape, thicker at its margins than at its center, and completes the separation between the nasal cavities" [https://en.wikipedia.org/wiki/Septal_nasal_cartilage, MGI:anna]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0030205	thick nasal septum	"increased width of the dividing wall that runs down the midline of the nose, separating the nasal cavity into the two nostrils" [HP:0009746, MGI:anna]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J
MP:0030250	frontonasal prominence hypoplasia	"underdevelopment or reduced size, usually due to a reduced number of cells, of the unpaired embryonic process that is formed from the tissues surrounding the forebrain vesicle and develops into the forehead and bridge of the nose/snout" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm1Jpa/Fgfr1^tm1Jpa Genetic Background: involves: 129 Allelic Composition: Fgfr2^tm1Dor/Fgfr2^tm1Dor,Foxg1^tm1(cre)Skm/Foxg1⁺,Fgfr1^tm3.1Sor/Fgfr1^tm1Jpa Genetic Background: involves: 129
MP:0030265	parietal bossing	"an area of marked prominence or protrusion in the parietal region" [HP:0004641, MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030275	thin frontal bone	"reduced thickness of the single bone forming the forehead and roof of the eye orbit" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0030281	thin parietal bone	"reduced thickness of the paired membranous bones located between the frontal and occipital bones that are large, curved and quadrilateral in outline, articulate with each other at the midline in the sagittal suture, and form most of the superior and lateral aspects of the cranium" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N
MP:0030301	abnormal maxillary frontal process morphology	"any structural anomaly of the upward extension from the body of the maxilla which articulates with the frontal bone; the frontal process has a vertical ridge which constitutes the medial border of the orbit (anterior lacrimal crest); posteriorly it forms the lacrimal groove together with the lacrimal bone; superomedially it is in close contact with the anterior ethmoidal sinuses" [http://www.medilexicon.com/dictionary/72273, https://www.kenhub.com/en/library/anatomy/the-maxilla]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030302	abnormal maxillary zygomatic process morphology	"any structural anomaly of the rough triangular eminence situated at the angle of separation of the anterior, zygomatic, and orbital surfaces; in front, it forms part of the anterior surface; behind, it is concave, and forms part of the infratemporal fossa; above, it is rough and serrated for articulation with the zygomatic bone; below, it presents the prominent arched border which marks the division between the anterior and infratemporal surfaces" [https://en.wikipedia.org/wiki/Zygomatic_process_of_maxilla]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0030315	small neurocranium	"decreased size of the bones of the skull enclosing the brain" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030350	premature coronal suture closure	"early closure of the coronal suture of the skull" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2.3Dsn/Fgfr2⁺ Genetic Background: involves: 129 * C57BL/6 * FVB/N Allelic Composition: Fgfr2^tm4Lni/Fgfr2⁺ Genetic Background: Not Specified Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * FVB/N Allelic Composition: Fgfr2^tm1Schl/Fgfr2⁺ Genetic Background: involves: 129S1/Sv Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6 Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^m1Sgg/Fgfr2⁺ Genetic Background: involves: C3H/HeJ * C57BL/6J Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030356	premature lambdoid suture closure	"early closure of the lambdoid suture of the skull" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030358	premature squamoparietal suture closure	"early closure of the squamoparietal suture of the skull" [MGI:anna]	Show Allelic Composition: Alx3^tm1Hubr/Alx3^tm1Hubr,Alx4^lst-J/Alx4^lst-J Genetic Background: involves: 129P2/OlaHsd * C3H * C57BL/6J * FVB/N Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0030390	premature facial suture closure	"early closure of one or more of the joints (sutures) between facial bones" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030391	premature zygomaticomaxillary suture closure	"early closure of the suture between the zygomatic process of the maxilla and the maxillary margin of the zygomatic bone" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm3Ewj/Fgfr2⁺ Genetic Background: B6.129-Fgfr2^tm3Ewj
MP:0030420	short basicranium	"decreased length of the anterior and/or posterior portions of the skull base" [MGI:anna]	Show Allelic Composition: Fgfr2^tm4Lni/Fgfr2^tm4Lni Genetic Background: Not Specified Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd
MP:0030424	premature palatomaxillary suture closure	"early closure of the transverse suture across the back of the hard palate that separates the maxillary shelf of the palate from the horizontal plates of the palatine bones" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030425	wide intermaxillary suture	"an abnormally increased width of the anterior median suture between the two maxillae of the upper jawbone for age-related norms" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030431	wide metopic suture	"an abnormally increased width of the metopic suture for age-related norms" [MGI:anna]	Show Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * FVB/N
MP:0030434	premature maxillary-premaxillary suture closure	"early closure of the maxillary-premaxillary suture, the line of union of the two portions of the maxilla (pre- and postmaxilla)" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030436	premature frontonasal suture closure	"early closure of the joint (suture) between the frontal bone and the two nasal bones" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Cxd/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB/N
MP:0030437	abnormal osteoblast proliferation	"anomaly in the ability of osteoblasts to undergo expansion by cell division; osteoblasts are skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell" [MGI:anna]	Show Allelic Composition: Fgfr2^tm3.1Lni/Fgfr2^tm3.1Lni Genetic Background: involves: 129S1/Sv * 129X1/SvJ * BALB/c * C57BL/6
MP:0030438	increased osteoblast proliferation	"increase in the expansion rate of osteoblasts by cell division; osteoblasts are skeletogenic cells that secrete osteoid, are capable of producing mineralized (hydroxyapatite) matrix, are located adjacent to or within osteoid tissue, and arise from the transformation of a preosteoblast cell" [MGI:anna]	Show Allelic Composition: Fgfr2^tm2Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm2Ewj Tg(EIIa-cre)C5379Lmgd Allelic Composition: Fgfr2^tm1Ewj/Fgfr2⁺,Tg(EIIa-cre)C5379Lmgd/0 Genetic Background: B6.Cg-Fgfr2^tm1Ewj Tg(EIIa-cre)C5379Lmgd
MP:0030464	abnormal cranial cartilage morphology	"any structural anomaly of any cartilage element that is part of the cranial skeleton" [UBERON:0003933]	Show Allelic Composition: Fgfr2^m1Sgg/Fgfr2^m1Sgg Genetic Background: involves: C3H/HeJ * C57BL/6J

Interacting proteins (from Reactome)

Interactor ID

Name

Interaction type

No match

1 s.

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