MP:0000015 | abnormal ear pigmentation | "anomaly in the coloration of the ear" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0000031 | abnormal cochlea morphology | "any anomaly, deformity, malformation, impairment or dysfunction of the cochlea" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator, J:21484] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000042 | abnormal organ of Corti | "abnormalities associated with the highly specialized epithelium in the floor of the ductus cochlearis; also referred to a spiral organ (organum spirale), or acoustic papilla" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0000043 | organ of Corti degeneration | "a retrogressive impairment of function or destruction of the highly specialized epithelium in the floor of the ductus cochlearis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0000048 | abnormal stria vascularis | "anomalous structure of the layer of highly vascularized pigmented granular cells on the outer wall of the cochlear duct" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0000183 | decreased circulating LDL cholesterol level | "less than average concentration in the blood of low density lipoprotein, which normally transports cholesterol to tissues other than the liver" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
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MP:0000186 | decreased circulating HDL cholesterol level | "lower than average level of high density lipoprotein in blood; this molecule transports cholesterol to the liver for excretion in bile" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
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MP:0000208 | decreased hematocrit | "less than the average percentage of a volume of a blood sample occupied by red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
Allelic Composition: f/f,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
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MP:0000245 | abnormal erythropoiesis | "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: Runx1tm3.1Spe/Runx1tm3.1Spe Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0000248 | macrocytosis | "condition in which erythrocytes are larger than normal in size" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0000267 | abnormal cardiac development | "aberrant formation or incomplete differentiation of the heart" [MGI:cls, J:53370] |
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Allelic Composition: Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol,Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol,Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB
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MP:0000324 | increased mast cell number | "greater than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0000333 | decreased bone marrow cell number | "decreased number of cells that make up the core cavities of bones when compared to the norm" [tc:Teresa Chu , Mouse Genome Informatics Curator, J:60896] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
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MP:0000336 | decreased mast cell number | "fewer than expected number of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kittm1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kittm1Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-n/KitW-n Genetic Background: Not Specified
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: KitW-Btlr/KitW-Btlr Genetic Background: C57BL/6J-KitW-Btlr
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-Jic/KitW Genetic Background: involves: C57BL/6 * WB
Allelic Composition: KitW-Jic/Kit+ Genetic Background: involves: C57BL/6
Allelic Composition: KitW-42J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-42J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J
Allelic Composition: KitW-n/KitW Genetic Background: involves: WB
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * C57BL/6
Allelic Composition: KitW/Kit+,Tg(PGK1-KITLG*220)441Daw/0 Genetic Background: involves: C3H/HeJ
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
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MP:0000343 | altered response to myocardial infarction | "change in the physiological response to necrosis of the cardiac tissue, often resulting from the sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0000370 | head blaze | "the appearance of a stripe of white fur on the head" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-39H/Kit+ Genetic Background: involves: BALB/cCrl * C3H/HeNCrl
Allelic Composition: KitW-57J/KitW-57J Genetic Background: involves: C58/J
Allelic Composition: KitMhdasow3/Kit+ Genetic Background: C3HeB/FeJ-KitMhdasow3
Allelic Composition: KitWhc1/Kit+ Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: involves: C3H/HeN * C57BL/6
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MP:0000371 | diluted coat color | "a coat color that appears lighter in intensity or paler than normal" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-f/Kit+ Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-n/Kit+ Genetic Background: Not Specified
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/Kit+ Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: C57BL/6J-KitW-2Btlr
Allelic Composition: KitW-29H/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-39J/Kit+ Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-41J/Kit+ Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-b/Kit+ Genetic Background: involves: C57BL/St
Allelic Composition: KitW-Jic/Kit+ Genetic Background: involves: C57BL/6
Allelic Composition: KitW-42J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * C57BL/6
Allelic Composition: KitW-v/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-e/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * DBA
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MP:0000372 | irregular coat pigmentation | "uneven coloration of the hair" [J:65030] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: KitW/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-ei/Kit+ Genetic Background: C57BL-KitW-ei
Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-n/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-37J/Kit+ Genetic Background: C57BL/6J-KitW-37J/J
Allelic Composition: KitW-41J/KitW-41J Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-v/Kit+,Rw/Rw+ Genetic Background: involves: 101/H * C3H/HeH * C57BL
Allelic Composition: KitW-v/Kit+,Ph/Ph+ Genetic Background: involves: C57BL
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MP:0000373 | belly spot | "the appearance of a round area of white fur on the belly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-39H/Kit+ Genetic Background: involves: BALB/cCrl * C3H/HeNCrl
Allelic Composition: Kittm1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-57J/KitW-57J Genetic Background: involves: C58/J
Allelic Composition: KitW-57J/Kit+ Genetic Background: involves: C58/J
Allelic Composition: KitW-44J/Kit+ Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: KitW-f/Kit+ Genetic Background: involves: C3H/HePas
Allelic Composition: KitWads/Kit+ Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kitd18/Kit+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitMhdasow3/Kit+ Genetic Background: C3HeB/FeJ-KitMhdasow3
Allelic Composition: KitWhc1/Kit+ Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-Btlr/Kit+ Genetic Background: C57BL/6J-KitW-Btlr
Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: C57BL/6J-KitW-2Btlr
Allelic Composition: KitW-39J/Kit+ Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-41J/Kit+ Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-a/Kit+ Genetic Background: involves: Z
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * DBA
Allelic Composition: KitW-3Bao/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: Kittm1Rosay/Kit+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: KitW-31H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-32H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-38H/Kit+ Genetic Background: Not Specified
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
Allelic Composition: Mitftm7.1Arnh/Mitftm7.1Arnh,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
Allelic Composition: KitWps/Kit+ Genetic Background: involves: C57BL/6J * CBA/CaJ
Allelic Composition: KitWps/Kit+,Pax3Sp-1Wli/Pax3+ Genetic Background: involves: C57BL/6J * CBA/CaJ
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MP:0000414 | alopecia | "absence of hair or loss of hair; not usually in reference to primary genetic hairlessness but may be due to dietary, stress, secondary to immune condition" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:30772, J:33796] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0000462 | abnormal digestive system morphology | "anomalous structure of the system dedicated to the mechanical, chemical, and enzymatic processing of food" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2
Allelic Composition: Kittm1Bpr/Kit+ Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Allelic Composition: Kittm1Shta/Kit+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
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MP:0000467 | abnormal esophagus morphology | "malformation of the part of the digestive canal through which food passes from the pharynx to the stomach" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
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Allelic Composition: Cdh23v-8J/Cdh23v-8J Genetic Background: C57BL/6J-Cdh23v-8J/J
Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Allelic Composition: Kittm1Shta/Kit+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
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MP:0000494 | abnormal cecum morphology | "malformation of the large sac at the ileum and large intestine junction" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
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MP:0000691 | enlarged spleen | "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0000693 | spleen hyperplasia | "increased cell number in the spleen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33401] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0000694 | spleen hypoplasia | "small size due to reduced cell number in the spleen" [J:43971] |
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Allelic Composition: Runx1tm3.1Spe/Runx1tm3.1Spe Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0000715 | decreased thymocyte number | "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
Allelic Composition: KitW/KitW,Tg(PDGFB-EPO)321Zbz/? Genetic Background: involves: C3H * C57BL/6
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MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0001125 | abnormal oocytes | "anomalous structure of immature ova" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0001126 | abnormal ovary morphology | "malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Lrp6rs/Lrp6rs Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0001127 | small ovary | "reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-41J/KitW-41J Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-39J/KitW-41J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-41J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
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MP:0001128 | ovary hyperplasia | "increased cell number in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0001129 | impaired ovarian folliculogenesis | "a block in the formation of the spherical ovum in the ovary" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0001130 | abnormal ovarian folliculogenesis | "atypical formation or failure to form the spherical ovum in the ovary" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:35782] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0001131 | abnormal ovarian follicles | "malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0001143 | constricted vaginal opening | "shrunken, narrowed external vaginal opening" [J:50844] |
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Allelic Composition: Vangl1Gt(XL802)Byg/Vangl1+,Vangl2Lp/Vangl2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * LPT/LeJ
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MP:0001145 | abnormal male reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-42J/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
Allelic Composition: KitW-19H/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
Allelic Composition: KitW-35J/Kit+ Genetic Background: C57BL/6J-KitW-35J/J
Allelic Composition: KitW-38J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-40J/Kit+ Genetic Background: C57BL/6J-KitW-40J/J
Allelic Composition: KitW-43J/Kit+ Genetic Background: C57BL/6J-KitW-43J/J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
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MP:0001152 | Leydig cell hyperplasia | "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0001155 | arrest of spermatogenesis | "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271] |
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Allelic Composition: Dmdtm1.1Khan/Y Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: B6.129S1-Kittm1.1Bsm
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: KitMhdasow3/KitMhdasow3 Genetic Background: C3HeB/FeJ-KitMhdasow3
Allelic Composition: Kittm1Alf/KitMhdasow3 Genetic Background: involves: 129S2/SvPas * C3HeB/FeJ
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-j/KitW-j Genetic Background: involves: C3H
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MP:0001183 | overexpanded alveoli | "expanded volume of the saclike terminal dilation of the respiratory bronchioles" [J:66345] |
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Allelic Composition: Tbx1tm2.1Bem/Tbx1tm2.2Bem,Foxg1tm1(cre)Skm/Foxg1+ Genetic Background: involves: 129/Sv * C57BL/6 * SJL * Swiss Webster
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MP:0001188 | hyperpigmentation | "excess of pigment in any or all tissues or a part of a tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:50311] |
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Allelic Composition: Cdh23v-8J/Cdh23v-8J Genetic Background: C57BL/6J-Cdh23v-8J/J
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MP:0001189 | absent skin pigmentation | "lack of pigmentation of the skin" [J:53370] |
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Allelic Composition: KitW-Btlr/Kit+ Genetic Background: C57BL/6J-KitW-Btlr
Allelic Composition: KitW-31H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-32H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitWps/KitWps Genetic Background: involves: C57BL/6J * CBA/CaJ
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MP:0001190 | reddish skin | "skin has a more intense ruddy appearance than normal, often due to capillary congestion" [J:65038] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0001198 | tight skin | "skin has a taut, stretched appearance" [J:65038] |
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Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/Kit+ Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
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MP:0001261 | obese | "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm1Rosay/Kit+,Lepob/Lepob Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-v/KitW-v Genetic Background: C57BL/6J-KitW-v/J
Allelic Composition: f/f,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
Allelic Composition: KitW/KitW Genetic Background: B6.Cg-KitW/J
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MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptentm2.1Ppp/Ptentm2.1Ppp,Trp53tm1Thl/Trp53tm1Thl,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * C57BL/6 * DBA/2
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MP:0001324 | abnormal eye pigmentation | "change in the normal black pigmentation of the eye to another color, or lack of color" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Eportm1Jae/Eportm1Jae Genetic Background: either: (involves: 129S4/SvJae * BALB/c) or (involves: 129S4/SvJae * C57BL/6)
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MP:0001559 | hyperglycemia | "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Kittm1Rosay/Kit+,Lepob/Lepob Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0001577 | anemia | "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370] |
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Allelic Composition: GpnmbR150X/GpnmbR150X,Tyrp1isa/Tyrp1isa Genetic Background: involves: C57BL/6J * DBA/2J
Allelic Composition: KitSsm/KitSsm Genetic Background: involves: C57BL/10 * Non-inbred
Allelic Composition: KitW-57J/KitW-57J Genetic Background: involves: C58/J
Allelic Composition: KitW-pw/KitW-pw Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: KitW-27H/KitW-27H Genetic Background: CBA/H-KitW-27H
Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW-28H/KitW-28H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-36H/KitW-36H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-a/KitW-a Genetic Background: involves: Z
Allelic Composition: KitW-b/KitW-b Genetic Background: involves: C57BL/St
Allelic Composition: KitW-ct/KitW-ct Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-j/KitW-j Genetic Background: involves: C3H
Allelic Composition: KitW-73J/KitW-73J Genetic Background: involves: DBA/2J
Allelic Composition: KitW-s/KitW-s Genetic Background: involves: BRS
Allelic Composition: KitW-b/KitW-s Genetic Background: involves: BRS * C57BL/St
Allelic Composition: KitW-v/KitW-v,Ly6atm1Pmf/Ly6atm1Pmf Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitW-55J/KitW-55J Genetic Background: C57BL/6J-KitW-55J/J
Allelic Composition: KitW-55J/Kit+ Genetic Background: C57BL/6J-KitW-55J/J
Allelic Composition: KitW-Bs/KitW-v Genetic Background: involves: C57BL/6J
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MP:0001586 | abnormal erythrocyte count | "altered number of red blood cells per volume in the bloodstream" [J:53370] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: f/f,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
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MP:0001601 | abnormal myelopoiesis | "atypical process of bone marrow cell formation and/or bone marrow-derived blood cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0001619 | abnormal vascular permeability | "anomaly in the ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1Jus/Gt(ROSA)26Sor+,Tg(MMTV-cre)4Mam/0 Genetic Background: involves: C57BL/6J * C57BL/6N * FVB/N
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MP:0001663 | abnormal digestive system physiology | "altered function of the organ system that converts ingested food to nutrients and energy" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Psen1tm1Vln/Psen1tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0001802 | arrested B cell development | "inability to produce mature B cells, and accumulation of B cell precursors" [J:52607] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0001825 | arrested T cell development | "failure of T cell formation to proceed past a defined stage" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: B6.129S1-Kittm1.1Bsm
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MP:0001859 | kidney inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0001876 | decreased inflammatory response | "less than expected response to injury, infection, or insult" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: KitW-1Bao/Kit+ Genetic Background: C57BL/6J-KitW-1Bao
Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitWps/KitWps Genetic Background: involves: C57BL/6J * CBA/CaJ
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MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitWps/KitWps Genetic Background: involves: C57BL/6J * CBA/CaJ
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MP:0001924 | infertility | "inability to produce live offspring" [J:47225] |
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Allelic Composition: Kittm1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-Btlr/KitW-Btlr Genetic Background: C57BL/6J-KitW-Btlr
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-b/KitW-b Genetic Background: involves: C57BL/St
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: KitSsm/KitSsm Genetic Background: involves: C57BL/10 * Non-inbred
Allelic Composition: KitW-ei/KitW-ei Genetic Background: C57BL-KitW-ei
Allelic Composition: KitW-1Bao/Kit+ Genetic Background: C57BL/6J-KitW-1Bao
Allelic Composition: KitW-pw/Kit+ Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-pw/KitW-v Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: Kittm1Hntr/Kittm1Hntr Genetic Background: either: (involves: 129/Sv * C57BL/6 * DBA/2) or (involves: 129S1)
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: KitMhdasow3/KitMhdasow3 Genetic Background: C3HeB/FeJ-KitMhdasow3
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-55J/KitW-55J Genetic Background: C57BL/6J-KitW-55J/J
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: KitW-ei/KitW-ei Genetic Background: C57BL-KitW-ei
Allelic Composition: KitW-pw/Kit+ Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-pw/KitW-v Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: KitW-55J/KitW-55J Genetic Background: C57BL/6J-KitW-55J/J
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MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
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MP:0001940 | testicular hypoplasia | "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dmdtm1.1Khan/Y Genetic Background: involves: C57BL/6 * CBA
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MP:0001967 | deafness | "inability to hear" [J:57651] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0002014 | papilloma | "benign epithelial tumor" [J:47225] |
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Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL/6
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MP:0002016 | ovarian cysts | "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
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MP:0002052 | decreased tumor incidence | "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-v/KitW-v,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: KitW-v/Kit+,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
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MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitW-39H/Kit+ Genetic Background: involves: BALB/cCrl * C3H/HeNCrl
Allelic Composition: KitW-40H/KitW-40H Genetic Background: involves: BALB/c * C3H/HeN
Allelic Composition: KitW/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-82J/Kit+ Genetic Background: involves: C3HeB/FeLe
Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-ei/KitW-ei Genetic Background: C57BL-KitW-ei
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kittm1Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitMhdasco1/Kit+ Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/Kit+ Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitMhdasow3/KitMhdasow3 Genetic Background: C3HeB/FeJ-KitMhdasow3
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-bd/KitW-bd Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
Allelic Composition: KitW-x/KitW-x Genetic Background: involves: C3H/HeJ
Allelic Composition: KitW-x/Kit+ Genetic Background: involves: C3H/HeJ
Allelic Composition: KitW/Kit+,Tg(PGK1-KITLG*220)441Daw/0 Genetic Background: involves: C3H/HeJ
Allelic Composition: KitW-v/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-v/Kit+,Rw/Rw+ Genetic Background: involves: 101/H * C3H/HeH * C57BL
Allelic Composition: KitW-v/Kit+,Ph/Ph+ Genetic Background: involves: C57BL
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL
Allelic Composition: KitW-31H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-32H/Kit+ Genetic Background: Not Specified
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
Allelic Composition: KitW-Bs/KitW-v Genetic Background: involves: C57BL/6J
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MP:0002080 | prenatal lethality | "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Lrfn3tm1(KOMP)Vlcg/Lrfn3tm1(KOMP)Vlcg,Lrfn4tm1(KOMP)Vlcg/Lrfn4tm1(KOMP)Vlcg Genetic Background: involves: C57BL/6J * C57BL/6NTac
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MP:0002081 | perinatal lethality | "death anytime between E18.5 and postnatal day 1 " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-41J/Kit+ Genetic Background: C57BL/6J-KitW-41J/J
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MP:0002082 | postnatal lethality | "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Trbv14tm2Che/Trbv14tm2Che Genetic Background: involves: 129S4/SvJae
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-a/KitW-a Genetic Background: involves: Z
Allelic Composition: KitW-b/KitW-b Genetic Background: involves: C57BL/St
Allelic Composition: KitW-j/KitW-j Genetic Background: involves: C3H
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Cdh23v-8J/Cdh23v-8J Genetic Background: C57BL/6J-Cdh23v-8J/J
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Allelic Composition: Gusbmps/Gusbmps,KitW-41J/KitW-41J Genetic Background: B6(C)-KitW-41J Gusbmps/BrkJ
Allelic Composition: KitW-v/KitW-v,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: KitW-v/Kit+,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Allelic Composition: Cdkn1btm1Ako/Cdkn1b+,KitW-v/KitW-v Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0002095 | abnormal skin pigmentation | "variation of skin color or complexion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-82J/Kit+ Genetic Background: involves: C3HeB/FeLe
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0002106 | abnormal muscle physiology | "anomolous function of the muscle, not due to an anatomical defect" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Psen1tm1Vln/Psen1tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
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MP:0002123 | abnormal hematopoiesis | "abnormal development of the enucleated fetal and adult erythrocytes that develop in the aorta, genital ridge and mesonephros region and later in the fetal and adult liver" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
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MP:0002144 | abnormal B lymphocyte development | "atypical production of or inability to produce mature B cells, and/or accumulation of B cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
Allelic Composition: KitW/KitW,Tg(PDGFB-EPO)321Zbz/? Genetic Background: involves: C3H * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002145 | abnormal T lymphocyte development | "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
Allelic Composition: KitW/KitW,Tg(PDGFB-EPO)321Zbz/? Genetic Background: involves: C3H * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002213 | true hermaphroditism | "having both ovarian and testicular tissue present" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-42J/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
Allelic Composition: KitW-42J/Kit+,X/SryPOS-TIR Genetic Background: involves: C57BL/6J
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MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Dmdtm1.1Khan/Y Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: KitW-3Bao/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-2Bao/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
Allelic Composition: KitWads/Kit+ Genetic Background: involves: C57BL/6J
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MP:0002335 | decreased airway responsiveness | "less easily provoked into bronchoconstriction during bronchial provocation testing" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0002416 | abnormal proerythroblast morphology/development | "anomalous structure, formation, or numbers of the immature, nucleated erythrocyte precursors that give rise to reticulocytes " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Runx1tm3.1Spe/Runx1tm3.1Spe Genetic Background: involves: 129S4/SvJae * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0002423 | abnormal mast cell physiology | "anomalous response of the granulated cells found in most tissues and which contain large amounts of histamine and heparin in granules" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-Jic/KitW Genetic Background: involves: C57BL/6 * WB
Allelic Composition: KitW-42J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-n/KitW Genetic Background: involves: WB
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002429 | abnormal blood cell morphology/development | "anomalous structure, differentiation, or number of any of the cells found in the blood" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0002447 | abnormal erythrocyte morphology | "structural anomaly of the cells in the blood that carry oxygen, red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0002494 | increased IgM | "greater than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002495 | increased IgA | "greater than normal immunoglobulin class A level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002497 | increased IgE | "greater than normal immunoglobulin class E level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002503 | abnormal histamine physiology | "functional anomaly of this amine that is involved in local immune response, in regulating physiological function in the gut, and that acts as a neurotransmitter" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
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MP:0002590 | increased mean corpuscular volume | "greater than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0002591 | decreased mean corpuscular volume | "less than the average amount of space occupied by each red blood cell, calculated from the hematocrit and red cell count, in erythrocyte indices" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: f/f,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0002593 | high mean erythrocyte count | "greater than average numbers of red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: f/f+,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
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MP:0002594 | low mean erythrocyte count | "less than average numbers of red blood cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
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MP:0002599 | increased mean platelet volume | "increased content of platelet cells over the norm" [cml:Cathleen M. Lutz, Mouse Genome Informatics Curator] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitWads/Kit+ Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0002606 | increased basophil count | "higher than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MPD:Mouse Phenome Database] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002607 | decreased basophil count | "lower than average number of basophils as measured by the percent of the total number of leukocytes" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, MPD:Mouse Phenome Database] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
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MP:0002608 | increased hematocrit | "greater than average percentage of a volume of a blood sample occupied by red blood cells" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: f/f+,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0002628 | fatty liver | "an accumulation of fat deposits in the liver " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: Kittm1Alf/KitMhdasow3 Genetic Background: involves: 129S2/SvPas * C3HeB/FeJ
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6J
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MP:0002671 | belted | "the appearance of a stripe of white fur around the circumference of the abdomen" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-bd/KitW-bd Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
Allelic Composition: KitW-27H/KitW-27H Genetic Background: CBA/H-KitW-27H
Allelic Composition: Adamts20bt-2H/Adamts20bt-2H,Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Adamts20bt-2H/Adamts20bt-2H,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0002675 | asthenozoospermia | "loss or reduction of the mobility of the spermatozoa, frequently associated with infertility" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0002685 | abnormal proliferation of spermatogonia | "reduction in the proliferation of the spermatogonial stem cells either due to reduced mitosis or increased apoptosis" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:62271] |
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Allelic Composition: Kittm1Hntr/Kittm1Hntr Genetic Background: either: (involves: 129/Sv * C57BL/6 * DBA/2) or (involves: 129S1)
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MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0002743 | glomerulonephritis | "glomerular disease characterized by diffuse inflammatory reaction that is not the acute response to infection of the kidneys" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002777 | absent ovarian follicles | "lack of the sac-like structures in the ovaries that surround the ova" [J:42612, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0002784 | abnormal Sertoli cell morphology | "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Foxc1tm1Blh/Foxc1tm1Blh,Foxc2tm1Blh/Foxc2tm1Blh Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0002810 | microcytic anemia | "anemia in which the circulating erythrocyte corpuscular volume is smaller than normal" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW-24J/Kit+ Genetic Background: Not Specified
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MP:0002811 | macrocytic anemia | "anemia in which the circulating erythrocyte corpuscular volume is larger than normal" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: KitW/KitW Genetic Background: Not Specified
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: C57BL/6
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL/6
Allelic Composition: KitW-42J/KitW-42J Genetic Background: C57BL/6J-KitW-42J/J
Allelic Composition: KitW-f/Kit+ Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitW-n/KitW-n Genetic Background: Not Specified
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/Kit+ Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-41J/KitW-41J Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-41J/Kit+ Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-ct/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-rio/KitW-rio Genetic Background: DBA/2-KitW-rio
Allelic Composition: KitW-v/KitW-v Genetic Background: C57BL/6J-KitW-v/J
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * DBA
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
Allelic Composition: KitW/KitW Genetic Background: B6.Cg-KitW/J
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MP:0002855 | abnormal cochlear ganglion morphology | "malformation, malfunction or absence of the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain and resides on the cochlear part of the vestibulocochlear nerve (eighth cranial nerve)" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002857 | cochlear ganglion degeneration | "loss of neural cell bodies in the group of nerve cell bodies that conveys auditory sensation from the organ of Corti to the hindbrain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002871 | albuminuria | "presence of excess albumin in the urine" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0002872 | polycythemia | "an excess of circulating red blood cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW-34J/KitW-34J Genetic Background: C57BL/6J-KitW-34J/J
Allelic Composition: KitW-35J/Kit+ Genetic Background: C57BL/6J-KitW-35J/J
Allelic Composition: KitW-37J/Kit+ Genetic Background: C57BL/6J-KitW-37J/J
Allelic Composition: KitW-38J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-40J/Kit+ Genetic Background: C57BL/6J-KitW-40J/J
Allelic Composition: KitW-43J/Kit+ Genetic Background: C57BL/6J-KitW-43J/J
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0002874 | decreased hemoglobin content | "decrease in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0002875 | decreased erythrocyte count | "reduced number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-Jic/Kit+ Genetic Background: involves: C57BL/6
Allelic Composition: KitW-42J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0002877 | abnormal melanocyte morphology | "malformation of the cells that produce pigment " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
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MP:0002894 | abnormal otoliths | "malformed crystalline calciferous particles adhering to the otolithic membrane" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0002938 | white spotting | "the appearance of patches of white fur" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-39H/Kit+ Genetic Background: involves: BALB/cCrl * C3H/HeNCrl
Allelic Composition: KitW-40H/KitW-40H Genetic Background: involves: BALB/c * C3H/HeN
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kittm1Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: KitW-pw/Kit+ Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-44J/Kit+ Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: KitW-f/KitW-f Genetic Background: involves: C3H/HePas
Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: involves: C3H/HeN * C57BL/6
Allelic Composition: Adamts20bt-2H/Adamts20bt-2H,Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Adamts20bt-2H/Adamts20bt-2H,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: KitW-17J/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-18J/Kit+ Genetic Background: involves: C3HeB/Fe * C57BL/6
Allelic Composition: KitW-20J/Kit+ Genetic Background: C57BL/6J-KitW-20J/J
Allelic Composition: KitW-24J/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-28H/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-29H/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: a/a,KitW-2J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/Kit+ Genetic Background: C57BL/6J-KitW-37J/J
Allelic Composition: KitW-36H/KitW-36H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-45J/Kit+ Genetic Background: involves: DBA/2J
Allelic Composition: KitW-49J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-51J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-59J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-80J/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-b/Kit+ Genetic Background: involves: C57BL/St
Allelic Composition: KitW-j/Kit+ Genetic Background: involves: C3H
Allelic Composition: KitW-Jic/Kit+ Genetic Background: involves: C57BL/6
Allelic Composition: KitW-42J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/Kit+ Genetic Background: involves: C57BL/6 * C57BL/6J
Allelic Composition: KitW-n/Kit+ Genetic Background: involves: WB
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * C57BL/6
Allelic Composition: KitW-70J/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-73J/Kit+ Genetic Background: involves: DBA/2J
Allelic Composition: KitW-rio/Kit+ Genetic Background: DBA/2-KitW-rio
Allelic Composition: KitW-rio/Kit+ Genetic Background: involves: C57BL/6 * DBA/2
Allelic Composition: KitW-s/Kit+ Genetic Background: involves: BRS
Allelic Composition: KitW-55J/Kit+ Genetic Background: C57BL/6J-KitW-55J/J
Allelic Composition: KitW-3Bao/Kit+ Genetic Background: involves: C57BL/6J
Allelic Composition: f/f,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
Allelic Composition: f/f+,KitW/Kit+ Genetic Background: FL/1Re-KitW/J
Allelic Composition: Kittm1Rosay/Kit+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Kittm1Rosay/Kit+,Lepob/Lepob Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: KitW-38H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitWps/Kit+,Pax3Sp-1Wli/Pax3+ Genetic Background: involves: C57BL/6J * CBA/CaJ
Allelic Composition: KitW-84J/Kit+ Genetic Background: involves: 129S2/SvPas * C57BL/6J
Allelic Composition: KitW-85J/Kit+ Genetic Background: C57BL/6J-KitW-85J/GrsrJ
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MP:0002939 | head spot | "the appearance of a round area of white fur on the head" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-f/Kit+ Genetic Background: involves: C3H/HePas
Allelic Composition: KitWads/Kit+ Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL * DBA
Allelic Composition: KitW-v/Kit+,Rw/Rw+ Genetic Background: involves: 101/H * C3H/HeH * C57BL
Allelic Composition: KitW-31H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-32H/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-38H/Kit+ Genetic Background: Not Specified
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MP:0002940 | variable body spotting | "the appearance of patches of white fur at random on the coat" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-v/Kit+,Snai2tm2Grid/Snai2tm2Grid Genetic Background: involves: 129S1/Sv * C57BL
Allelic Composition: KitW-v/Kit+,Snai2tm2Grid/Snai2+ Genetic Background: involves: 129S1/Sv * C57BL
Allelic Composition: KitW-Bs/Kit+ Genetic Background: C57BL/6J
Allelic Composition: KitSsm/Kit+ Genetic Background: involves: C57BL/10 * Non-inbred
Allelic Composition: KitW-sh/Kit+ Genetic Background: involves: 101/H * C3H/HeH * CBA
Allelic Composition: KitW-2Bao/Kit+ Genetic Background: C57BL/6J-KitW-2Bao
Allelic Composition: KitW-3Bao/Kit+ Genetic Background: C57BL/6J-KitW-3Bao
Allelic Composition: KitW-1Bao/Kit+ Genetic Background: C57BL/6J-KitW-1Bao
Allelic Composition: KitW-19H/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitWads/Kit+ Genetic Background: C57BL/6J-KitWads
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/Kit+ Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: C57BL/6J-KitW-2Btlr
Allelic Composition: KitW-v/Kit+ Genetic Background: Not Specified
Allelic Composition: KitW-e/Kit+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0002962 | increased protein excretion | "greater than the normal amount of serum proteins voided by the kidneys" [RGD:Rat Genome Database submission] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0002982 | abnormal germ cell migration | "defects in the orderly movement of a germ cell, a cell specialized to produce haploid gametes, from one site to another during development" [ava:Anna V. Anagnostopoulos , Mouse Genome Informatics Curator] |
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Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1 Genetic Background: involves: C57BL/6
Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0003037 | increased infarction size | "increased size of necrotic area from normal of the myocardium resulting from a sudden insufficiency of arterial or venous blood supply due to emboli, thrombi or mechanical factors" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0003071 | decreased vascular permeability | "reduced or slower ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0003131 | increased erythrocyte count | "greater number of the cells in the blood that carry oxygen, red blood cells, per unit" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0003135 | increased erythrocyte precursors | "greater numbers of progenitors of the erythrocyte lineage" [smb:Susan M. Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0003143 | enlarged otoliths | "increased average size of the crystalline calciferous particles adhering to the otolithic membrane" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:67072] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003149 | abnormal tectorial membrane morphology | "malformation, malfunction or absence of the overlaying membrane of cochlear duct, an extracellular matrix of the inner ear that contacts the stereocilia bundles of specialized sensory hair cells; sound induces movement of these hair cells relative to the tectorial membrane, deflects the stereocilia, and leads to fluctuations in hair cell membrane potential, transducing sound into electrical signals" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:77634] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0003175 | reversion by mitotic recombination | "cross-over event between sequences containing mutant and wild-type alleles during DNA replication in a heterozygote resulting in cells with two wild-type alleles" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-rio/Kit+ Genetic Background: involves: C57BL/6 * DBA/2
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MP:0003270 | intestinal obstruction | "any impediment, blockage, or reversal of the normal flow of the intestinal contents toward the anus " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
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MP:0003277 | esophageal papilloma | "benign epithelial tumor of the esophagus" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL/6
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MP:0003289 | abnormal intestinal peristalsis | "altered intestinal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls of the bowel that move bowel contents forward" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Ptch1tm1Mps/Ptch1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1(cre/ERT2)Dsa/Kit+,Prkg1tm2Naw/Prkg1tm2Naw Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0003301 | peptic ulcer | "any lesion on the mucosal surface of the portion of the alimentary tract that is exposed to gastric acid, usually in the stomach or the duodenum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL/6
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MP:0003436 | resistance to induced arthritis | "less likely to be striken with changes in the synovial membranes and thickening of articular structures, widespread degeneration of the collagen fibers in connective tissues, and by atrophy and rarefaction of bony structures that are induced by inflammatory responses caused by chemical or mechanical agents" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:75303] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
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MP:0003447 | reduced tumor growth/size | "less than expected development of tumorous growth when compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:65383] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0003507 | abnormal ovary physiology | "anomaly or loss either the production of female germ cells or the endocrine cells for the production of estrogen and progesterone" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Snap91tm1.1Tmar/Snap91+,Vamp2tm1Sud/Vamp2+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Allelic Composition: Cdkn1btm1Ako/Cdkn1b+,KitW-v/KitW-v Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
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MP:0003635 | abnormal synaptic transmission | "defect in the communication from a neuron to a target across a synapse " [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Ptch1tm1Mps/Ptch1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0003638 | abnormal response/metabolism to endogenous compounds | "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL * C57BL/6 * WB
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0003698 | abnormal male reproductive system physiology | "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0003705 | abnormal hypodermis morphology | "malformed or atypical condition of the innermost and thickest layer of the skin composed of loose connective tissue containing adipoctyes" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
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MP:0003717 | pallor | "an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW-28H/KitW-28H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0003721 | increased tumor growth/size | "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0004034 | belly blaze | "the appearance of a stripe or zigzag of white fur on the ventrum" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-a/Kit+ Genetic Background: involves: Z
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MP:0004200 | reduced fetal size | "smaller proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0004324 | vestibular hair cell degeneration | "degeneration or loss of the sensory epithelial cells of the maculae and cristae of the membranous labyrinth of the inner ear which are normally in synaptic contact with the vestibular nerve" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004362 | cochlear hair cell degeneration | "degeneration or loss of the sensory epithelial cells of the cochlea; these cells are in synaptic contact with the auditory nerve" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0004364 | thin stria vascularis | "reduced thickness of the stratified, secretory epithelium which lines the upper part of the cochlear spiral ligament and maintains potassium ion homeostasis in the endolymph" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0004365 | abnormal strial basal cells | "any structural abnormality in the polarized cells which are juxtaposed to fibrocytes in the underlying spiral ligament" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0004366 | abnormal strial marginal cells | "any structural abnormality in the polarized columnar cells of epithelial origin which cover the lateral surface of the cochlear duct, secrete potassium ions and form a continuous sheet in contact with the endolymph; marginal cells form extensive interdigitations with the basal and intermediate cells in the normal adult stria" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0004368 | abnormal stria vascularis vasculature | "any structural anomaly of the blood vessels supplying the stria vascularis in the cochlea of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0004381 | abnormal hair follicle melanocyte morphology | "any structural anomaly of the cells that produce pigment in the hair follicles" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Mitftm5.1Arnh/Mitftm5.1Arnh,Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6N
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MP:0004399 | abnormal cochlear outer hair cell morphology | "any structural abnormality in the sensory cells of the organ of Corti which are in synaptic contact with sensory as well as efferent fibers of the auditory nerve; there are three rows of columnar outer hair cells largely surrounded by cortilymph and supporting phalangeal cells; the apical end of each cell is anchored to the cuticular plate and about 100 stereocilia arranged in a V-shaped pattern extend from the cell s surface through the cuticular plate into the tectorial membrane" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0004410 | absent endocochlear potential | "absence of the electrical potential difference between the endolymphatic and perilymphatic compartments of the cochlea, indicating a primary defect in fluid homeostasis of the inner ear" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0004762 | increased anti-double stranded DNA antibody level | "increase in the level of antibodies that recognize double stranded DNA" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0004794 | increased anti-nuclear antigen antibody level | "elevated level of antibodies to nuclear antigens present in the sera" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0004805 | absent oocytes | "absence of mature germ cells in the female" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
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MP:0004810 | decreased hematopoietic stem cell number | "reduced cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gusbmps/Gusbmps,KitW-41J/KitW-41J Genetic Background: B6(C)-KitW-41J Gusbmps/BrkJ
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MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW-v/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
Allelic Composition: KitW-e/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
Allelic Composition: KitW-27H/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J * CBA/H
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MP:0004901 | decreased male germ cell number | "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
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MP:0004929 | decreased epididymis weight | "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0005014 | increased B cell number | "greater than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005016 | decreased lymphocyte number | "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0005017 | decreased B cell number | "fewer than normal B cell numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
Allelic Composition: KitW-vkd/KitW-vkd Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * WB
Allelic Composition: KitW/KitW,Tg(PDGFB-EPO)321Zbz/? Genetic Background: involves: C3H * C57BL/6
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0005027 | increased susceptibility to parasitic infection | "greater likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: Il3tm1Glli/Il3tm1Glli,KitW/KitW-v Genetic Background: involves: 129S2/SvPas * C57BL/6 * WB
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MP:0005058 | abnormal lysosome morphology | "anomalous structure of any of the cytoplasmic, membrane bound vesicles that contain a variety of hydrolases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Gusbmps/Gusbmps,KitW-41J/KitW-41J Genetic Background: B6(C)-KitW-41J Gusbmps/BrkJ
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MP:0005075 | abnormal melanosome morphology | "anomalous structure of these tissue-specific cytoplasmic organelles within which melanin pigments are synthesized and stored" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0005077 | abnormal melanogenesis | "failure of or anomaly in the biosynthetic pathway of melanin formation in cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:5346] |
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Allelic Composition: KitW-v/KitW-v,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
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MP:0005089 | decreased double-negative T cell count | "reduced numbers of the subset of T cells found in the thymus that express neither CD4 nor CD8
" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0005092 | decreased double-positive T cell count | "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0005159 | azoospermia | "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
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MP:0005171 | lack of coat pigmentation | "fur is devoid of coloration and appears white " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: KitW/KitW Genetic Background: Not Specified
Allelic Composition: Kittm1Bsm/Kittm1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-e/KitW-e Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-2Bao/KitW-2Bao Genetic Background: C57BL/6J-KitW-2Bao
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: C57BL/6J-KitW-3Bao
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kittm1Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: KitW-pw/Kit+ Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-pw/KitW-v Genetic Background: involves: STOCK Prop1df Myo5ad Bmp5se
Allelic Composition: KitW-n/KitW-n Genetic Background: Not Specified
Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: KitW-sh/KitW-v Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-Btlr/KitW-Btlr Genetic Background: C57BL/6J-KitW-Btlr
Allelic Composition: KitW-2Btlr/KitW-2Btlr Genetic Background: C57BL/6J-KitW-2Btlr
Allelic Composition: KitW-29H/KitW-29H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-39J/KitW-41J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-36H/KitW-bd Genetic Background: involves: 101/H * C3H/HeH * STOCK Rw Fgf5go Vps33abf
Allelic Composition: KitW-4Bao/KitW-4Bao Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-83J/KitW-v Genetic Background: involves: DLS/LeJ * MWT/Le
Allelic Composition: KitW-b/KitW-b Genetic Background: involves: C57BL/St
Allelic Composition: KitW-ct/KitW-ct Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-j/KitW-j Genetic Background: involves: C3H
Allelic Composition: KitW-Jic/KitW Genetic Background: involves: C57BL/6 * WB
Allelic Composition: KitW-42J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-37J/KitW Genetic Background: involves: C57BL/6 * C57BL/6J * WB
Allelic Composition: KitW-n/KitW Genetic Background: involves: WB
Allelic Composition: KitW-b/KitW-s Genetic Background: involves: BRS * C57BL/St
Allelic Composition: KitW-55J/KitW-55J Genetic Background: C57BL/6J-KitW-55J/J
Allelic Composition: KitW-31H/KitW-31H Genetic Background: Not Specified
Allelic Composition: KitW-32H/KitW-32H Genetic Background: Not Specified
Allelic Composition: KitW-38H/KitW-38H Genetic Background: Not Specified
Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH * CBA
Allelic Composition: KitWads/KitWps Genetic Background: involves: C57BL/6J * CBA/CaJ
Allelic Composition: KitWps/KitWps Genetic Background: involves: C57BL/6J * CBA/CaJ
Allelic Composition: KitW-85J/KitW-85J Genetic Background: C57BL/6J-KitW-85J/GrsrJ
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MP:0005175 | non-pigmented tail tip | "lack of color at the end of the tail " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:83500] |
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Allelic Composition: Kittm1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-f/Kit+ Genetic Background: involves: C3H/HePas
Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0005179 | decreased total circulating cholesterol level | "less than the normal concentration in the blood of these most abundant steroids in animal tissues, and precursors to steroid hormones and bile salts; also components of plasma membranes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
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MP:0005325 | abnormal glomerulus | "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0005402 | abnormal action potential | "change in the electric response of a nerve or other excitable tissue to its stimulation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-bd/KitW-bd Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
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MP:0005408 | hypopigmentation | "dilution of the pigment in the body" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW/Kit+,Tg(PGK1-KITLG*220)441Daw/0 Genetic Background: involves: C3H/HeJ
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MP:0005505 | increased platelet count | "greater than the normal numbers of the non-nucleated cells found in the blood and involved in blood coagulation " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0005535 | abnormal body temperature | "deviation in the level of heat natural to a living being" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
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MP:0005561 | increased mean corpuscular hemoglobin | "greater than the average levels of hemoglobin contained in an erythrocyte" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0005564 | increased hemoglobin content | "increase in the total hemoglobin content in the circulating blood" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, RGD:Rat Genome Database submission] |
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Allelic Composition: KitMhdasco1/KitMhdasco1 Genetic Background: C3HeB/FeJ-KitMhdasco1
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
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MP:0005597 | decreased susceptibility to type I hypersensitivity reaction | "less likelihood or resistance to developing a response manifested by localized or generalized reaction that occurs immediately (minutes) after exposure to an antigen to which the person/animal was previously sensitized; it is IgE-mediated, and mast cell activation and degranulation are hallmarks" [Pathology:ISBN 0-397-51047-0, J:68588, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6
Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: C57BL/6J
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MP:0005606 | increased bleeding time | "greater than the normal duration of blood flow after skin puncture; indicative of platelet and capillary function" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: KitW-v/KitW-v Genetic Background: involves: C57BL/6
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MP:0005641 | increased mean corpuscular hemoglobin concentration | "greater than the normal Hgb/Hct; the average hemoglobin concentration in a given volume of packed red cells, calculated from the hemoglobin therein and the hematocrit, in erythrocyte indices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:8936] |
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Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0005652 | sex reversal | "development of the reproductive system is inconsistent with the chromosomal sex " [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: KitW-42J/Kit+,X/SryPOS-TIR Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-19H/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
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MP:0005671 | response to transplant | "the body s reaction to the grafting of organs, tissues, or cells taken from the same individual for another area of the body or from another individual" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, cwg:Carroll-Ann W. Goldsmith, Mouse Genome Informatics curator, J:52834] |
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Allelic Composition: KitW-v/Kit+ Genetic Background: involves: C57BL/6
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MP:0006001 | abnormal intestinal transit time | "increase or decrease in the time it takes for a bolus of material to pass through the intestine" [smb:Susan M Bello, Mouse Genome Iformatics Curator] |
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Allelic Composition: Cdkn2ctm1Bbd/Cdkn2ctm1Bbd,Ptch1tm1Mps/Ptch1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1(cre/ERT2)Dsa/Kit+,Prkg1tm2Naw/Prkg1tm2Naw Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0006010 | absent cochlear melanocytes | "absence of cochlear melanocytes (neural crest-derived intermediate cells of the stria vascularis) that are required for normal cochlear development." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
Allelic Composition: KitW-v/KitW-v Genetic Background: involves: CBA/Ca
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MP:0006089 | abnormal saccule morphology | "malformation in the smaller of the two sacs in the vestibule" [smb:Susan M Bello, Mouse Genome Informatics Curator, Taber s Cyclopedic Medical Dictionary:19th edition: ISBN N 0-8036-0655-99, J:92940] |
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Allelic Composition: Fgfr2tm1.1Dsn/Fgfr2+ Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0006361 | abnormal female germ cell morphology | "any structural anomaly female germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
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MP:0006362 | abnormal male germ cell morphology | "any structural anomaly of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0006387 | abnormal T cell number | "deviation from the normal count of T cells" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0006410 | abnormal common myeloid progenitor cell morphology | "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
Allelic Composition: KitW-v/KitW-v,Ly6atm1Pmf/Ly6atm1Pmf Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0008000 | ovary tumor | "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Snap91tm1.1Tmar/Snap91+,Vamp2tm1Sud/Vamp2+ Genetic Background: involves: 129P2/OlaHsd * 129S6/SvEvTac * C57BL/6 * C57BL/6NTac
Allelic Composition: Cdkn1btm1Ako/Cdkn1b+,KitW-v/KitW-v Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * C57BL/6J * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N
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MP:0008031 | decreased Cajal-Retzius cell number | "reduced number of the distinct population of large, bipolar cells, distributed in a continuous band along the marginal zone of the cortex extending to the molecular layer of the dentate gyrus" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-bd/KitW-bd Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
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MP:0008208 | decreased pro-B cell number | "reduced number of the progenitor cells of the B cell lineage, with some lineage specific activity such as early stages of recombination of B cell receptor genes, but are not yet fully committed to the B cell lineage until the expression of PAX5 occurs" [CL:0000826, ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Faslpr/Faslpr Genetic Background: NOD.MRL-Faslpr
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MP:0008209 | decreased pre-B cell number | "reduced number of the cells in the B lymphocyte lineage that have undergone VDJ rearrangement of the immunoglobulin heavy chain and are in the process of V-J rearrangement of the light chain: these cells express mu heavy chain on the cell surface" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Flt3tm1Irl/Flt3tm1Irl,KitW/KitW-v Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0008237 | abnormal ventral coat pigmentation | "irregular or unusual pigmentation of ventrum hair in relation to control animals" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Kittm1.1Bsm/KitW Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Kittm3.1Bsm/KitW Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0008246 | abnormal leukocyte morphology | "any structural anomaly of nucleated cells of the myeloid or lymphoid lineages, found in blood or other tissue" [CL:0000738, MESH:A11.118.637] |
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Allelic Composition: Flt3tm1Irl/Flt3tm1Irl,KitW/KitW-v Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0008254 | increased megakaryocyte cell number | "greater number of giant cells 50 to 100 micron in diameter, with a greatly lobulated nucleus, found in the bone marrow; mature blood platelets are released from its cytoplasm" [CL:0000556, ISBN:0721601464] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0008390 | abnormal primordial germ cell proliferation | "anomaly in the ability of the primordial germ cell population to undergo rapid expansion by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1 Genetic Background: involves: C57BL/6
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MP:0008391 | abnormal primordial germ cell morphology | "any structural anomaly of a mesodermally-derived, most primitive undifferentiated sex cell, that originates in the allantois and migrates through the hindgut and into the gonadal ridge" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Nsun7Ste5Jcs1/Nsun7Ste5Jcs1 Genetic Background: involves: C57BL/6
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MP:0008489 | postnatal slow weight gain | "the weight gain over a span of postnatal developmental time is slower than controls, with or without ever attaining a similar weight to controls as adults" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
Allelic Composition: KitWhc1/KitWhc1 Genetic Background: involves: C3HeB/Fe * C57BL/6
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MP:0008501 | increased IgG2b level | "greater than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0008719 | impaired neutrophil recruitment | "reduced diffusion or accumulation of neutrophils in tissues or cells in response to a wide variety of substances released at the sites of inflammatory reactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0008750 | abnormal interferon level | "deviation from the normal levels of proteins secreted by vertebrate cells in response to a wide variety of inducers; they confer resistance against many different viruses, inhibit proliferation of normal and malignant cells, impede multiplication of intracellular parasites, enhance macrophage and granulocyte phagocytosis, augment natural killer cell activity, and show several other immunomodulatory functions" [MESH:D12.644.276.374.440] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0008751 | abnormal interleukin level | "deviation from the normal levels of soluble factors which stimulate growth-related activities of leukocytes as well as other cell types; they enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0008764 | increased mast cell degranulation | "increase in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell" [GO:0043303, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
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MP:0008765 | decreased mast cell degranulation | "reduction in the exocytosis of secretory granules containing preformed mediators such as histamine, serotonin, and neutral proteases by a mast cell" [GO:0043303, MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
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MP:0008770 | decreased survivor rate | "a smaller percentage of organisms than expected survive to adulthood and have a lifespan similar to controls" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-b/KitW-b Genetic Background: involves: C57BL/St
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MP:0008801 | abnormal erythroid progenitor cell morphology | "any structural anomaly of a progenitor cell committed to the erythroid lineage" [CL:0000038] |
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Allelic Composition: Runx1tm3.1Spe/Runx1tm3.1Spe Genetic Background: involves: 129S4/SvJae * C57BL/6
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MP:0008871 | abnormal ovarian follicle number | "abnormal numbers of spheroid cell aggregations in the ovary" [MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: Alx1tm1Crm/Alx1tm1Crm,Alx4tm1Rwi/Alx4tm1Rwi Genetic Background: involves: 129S6/SvEvTac * 129S7/SvEvBrd
Allelic Composition: KitW-44J/KitW-44J Genetic Background: B6.C3-KitW-44J/J
Allelic Composition: Kittm1.1Bsm/Kittm1.1Bsm Genetic Background: involves: 129S1/Sv * BALB/c * C57BL/6J * FVB/N
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-41J/KitW-41J Genetic Background: C57BL/6J-KitW-41J/J
Allelic Composition: KitW-39J/KitW-41J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-41J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
Allelic Composition: KitW-39J/KitW-44J Genetic Background: involves: C3H/HeJ * C57BL/6J
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
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MP:0008873 | increased sensitivity to xenobiotics | "decrease in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0008874 | decreased sensitivity to xenobiotics | "increase in the dose or concentration of a foreign compound required to induce a specific level of response" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0008976 | delayed female fertility | "ability of a female organism to produce live offspring occurring at a later than expected age" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-39J/KitW-v Genetic Background: involves: C57BL * C57BL/6J
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MP:0009205 | abnormal internal male genitalia morphology | "any structural anomaly of the internal masculine genital organs, including the testes, epididymides, deferent ducts, seminal vesicles, prostate, ejaculatory ducts, and bulbourethral glands" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-42J/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
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MP:0009247 | meteorism | "swelling of the abdomen resulting from gas in the intestinal or peritoneal cavity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009361 | abnormal primordial ovarian follicle morphology | "any structural abnormality in the ovarian follicle in which the primary oocyte is surrounded by a single layer of flattened follicular cells; primordial follicles are indiscernible to the naked eye and develop to primary, secondary, and finally mature vesicular follicles" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
Allelic Composition: KitW-3Bao/KitW-3Bao Genetic Background: involves: C57BL/6J
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MP:0009379 | abnormal foot pigmentation | "anomaly in the coloration of the foot" [MGI:mberry "Melissa Berry, Genetics Resources Curator"] |
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Allelic Composition: Kittm1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009476 | enlarged cecum | "increased size of the large sac at the ileum and large intestine junction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
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MP:0009477 | small cecum | "reduced size of the large sac at the ileum and large intestine junction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0009480 | distended cecum | "an expansion in the volume of the large sac at the ileum and large intestine junction, as by stretching or distention" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
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MP:0009485 | distended ileum | "an expansion in the volume of the portion of the small intestine that extends from the jejunum to the colon, as by stretching or distention" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
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MP:0009511 | distended stomach | "an expansion in the volume of the sac-like structure of the digestive canal between the esophagus and the small intestine, as by stretching or distention" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
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MP:0009515 | gastrointestinal stromal tumor | "non-epithelial, mesenchymal tumors of the gastrointestinal tract, thought to originate from the interstitial cells of Cajal, the pacemaker cells that regulate peristalsis in the digestive tract; approximately 70% of GISTs develop in the stomach, 20% in the small intestine, and less than 10% in the esophagus, colon, and rectum; GISTs are tumors of connective tissue, i.e. sarcomas, account for 1-3% of all gastrointestinal malignancies in human, and are typically more cellular than other gastrointestinal sarcomas" [http://en.wikipedia.org/wiki/Gastrointestinal_stromal_tumor, MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", OMIM:606764] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm1Bpr/Kittm1Bpr Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1Bpr/Kit+ Genetic Background: either: (involves: 129/Sv) or (involves: 129/Sv * C57BL/6)
Allelic Composition: Kittm1Shta/Kittm1Shta Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
Allelic Composition: Kittm1Shta/Kit+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * FVB/N
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MP:0009536 | abnormal interstitial cell of Cajal morphology | "any structural abnormality in the type of cell found in the gastrointestinal tract and serving as a pacemaker that triggers gut contraction; ICCs mediate inputs from the enteric nervous system to smooth muscle cells and are thought to be the cells from which gastrointestinal stromal tumours (GISTs) arise; abnormalities in the ICC network can cause chronic intestinal pseudo-obstruction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:16460275] |
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Allelic Composition: Psen1tm1Vln/Psen1tm1Vln,Tg(Thy1-APPLon)2Vln/0,Tg(Thy1-cre)1Vln/0 Genetic Background: involves: FVB/N
Allelic Composition: Kittm1Rosay/Kit+,Lepob/Lepob Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0009537 | interstitial cells of Cajal hyperplasia | "increased number of the pacemaker cells of the gastrointestinal tract which mediate inputs from the enteric nervous system to smooth muscle cells and trigger gut contraction" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator", PMID:16460275] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0009747 | impaired behavioral response to xenobiotic | "decreased sensitivity to a foreign compound capable of inducing the appearance of behavioral response, such as consumption preference, induced hyperactivity or stereotypic behavior, or increased dosage threshold for the appearance of the behavioral response" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh Genetic Background: involves: 101/H * C3H/HeH
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MP:0009763 | increased sensitivity to induced morbidity/mortality | "decrease in the amount of an external agent required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL * C57BL/6 * WB
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MP:0009766 | increased sensitivity to xenobiotic induced morbidity/mortality | "decrease in the amount of a foreign compound required to cause death or diseased state" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL * C57BL/6 * WB
Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0009783 | abnormal melanoblast morphology | "any structural anomaly of a cell that originates from the neural crest and differentiates into a pigment cell" [CL:0000541] |
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Allelic Composition: KitW-bd/KitW-bd Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
Allelic Composition: KitW-bd/Kit+ Genetic Background: involves: STOCK Rw Fgf5go Vps33abf
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MP:0009784 | abnormal melanoblast migration | "defect in the dispersion of the cells that originate from the neural crest and differentiate into pigment cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: Kittm1Alf/Kit+ Genetic Background: involves: 129S2/SvPas
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MP:0009854 | delayed gastric emptying | "an increase in the time required for solids or liquids to leave the stomach and enter the intestines" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Kittm1(cre/ERT2)Dsa/Kit+ Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6
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MP:0009932 | skin fibrosis | "invasion of fibrous connective tissue into the skin, often resulting from inflammation or injury" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
Allelic Composition: Fbn1Tsk/Fbn1+,KitW/Kit+ Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
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MP:0010016 | variable depigmentation | "absence or loss of normal pigment in the skin in various and irregular patterns" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-1Bao/Kit+ Genetic Background: C57BL/6J-KitW-1Bao
Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kittm1Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm1Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010215 | abnormal circulating complement protein level | "deviation from the normal levels of the serum proteins that act sequentially to allow for the direct killing of microbes, the disposal of immune complexes, and the regulation of other immune processes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-sh/KitW-sh,Lyntm1Ard/Lyntm1Ard Genetic Background: involves: 101 * 129P2/OlaHsd * C3H/HeH
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MP:0010275 | increased melanoma incidence | "greater than the expected number of malignant neoplasms, derived from melanocytes and occuring in pigmented tissues, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: KitW-v/KitW-v,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
Allelic Composition: KitW-v/Kit+,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
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MP:0010279 | increased gastrointestinal tumor incidence | "greater than the expected number of tumors originating in the gastrointestinal system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm4.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0010389 | mosaic coat color | "a random coat color pattern due to genetically different populations of cells in the skin e.g. as the result of X-inactivation" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW-v/KitW-v,Tg(Mt1-RET)304Ina/0 Genetic Background: involves: BALB/c * C57BL/6
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MP:0010769 | abnormal survival | "deviation from the expected viability or life span of an organism" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: KitW/KitW Genetic Background: B6.Cg-KitW/J
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MP:0010801 | abnormal myenteric nerve plexus morphology | "any structural anomaly of the plexus of unmyelinated nerve fibers and postganglionic autonomic cell bodies lying in the muscular coat of the esophagus, stomach and intestines that communicate with the submucosal, subserosal and enteric plexuses" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Kittm2Bsm/Kit+ Genetic Background: involves: 129X1/SvJ * C57BL/6J
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MP:0010831 | partial lethality | "the appearance of lower than Mendelian ratios of offspring of a given genotype due to death of some, but not all of the organisms" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Kittm5.1Bsm/Kit+ Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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MP:0011082 | abnormal gastrointestinal motility | "anomaly in the propulsive movements of the digestive system, resulting in the transit of the contents along the gastrointestinal tract" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(DTA)Jpmb/Gt(ROSA)26Sor+,Kittm1(cre/ERT2)Dsa/Kit+ Genetic Background: involves: 129S/SvEv * 129S6/SvEvTac * C57BL/6
Allelic Composition: Kittm1(cre/ERT2)Dsa/Kit+,Prkg1tm2Naw/Prkg1tm2Naw Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ * C57BL/6
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MP:0011084 | partial lethality at weaning | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms at weaning age" [MGI:csmith] |
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Allelic Composition: Kittm3Ber/Kittm3Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: KitW/KitW Genetic Background: Not Specified
Allelic Composition: KitW-e/KitW-e Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-27H/KitW-27H Genetic Background: CBA/H-KitW-27H
Allelic Composition: KitW-28H/KitW-28H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-ct/KitW-ct Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-73J/KitW-73J Genetic Background: involves: DBA/2J
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MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: KitW-19H/Kit+ Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitMhdasco5/KitMhdasco5 Genetic Background: C3HeB/FeJ-KitMhdasco5
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MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: KitSsm/KitSsm Genetic Background: involves: C57BL/10 * Non-inbred
Allelic Composition: Kittm1Alf/Kittm1Alf Genetic Background: involves: 129S2/SvPas
Allelic Composition: Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol Genetic Background: involves: 129/Sv * C57BL/6J
Allelic Composition: Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol,Gt(ROSA)26Sortm4(ACTB-tdTomato,-EGFP)Luo/Gt(ROSA)26Sor+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Kittm1.1(cre)Jmol/Kittm2.1(cre/Esr1*)Jmol,Gt(ROSA)26Sortm1(CAG-lacZ,-EGFP)Glh/Gt(ROSA)26Sor+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6J * FVB
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Kittm2Ber/Kittm2Ber Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Kittm2Ber/Kit+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: KitW-36H/KitW-36H Genetic Background: involves: 101/H * C3H/HeH
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MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: KitW-ei/KitW-ei Genetic Background: C57BL-KitW-ei
Allelic Composition: KitW-42J/KitW-42J Genetic Background: C57BL/6J-KitW-42J/J
Allelic Composition: KitW-34J/KitW-34J Genetic Background: C57BL/6J-KitW-34J/J
Allelic Composition: KitW-35J/KitW-35J Genetic Background: C57BL/6J-KitW-35J/J
Allelic Composition: KitW-36J/KitW-36J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-37J Genetic Background: C57BL/6J-KitW-37J/J
Allelic Composition: KitW-38J/KitW-38J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-40J/KitW-40J Genetic Background: C57BL/6J-KitW-40J/J
Allelic Composition: KitW-rio/KitW-rio Genetic Background: DBA/2-KitW-rio
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MP:0011090 | partial perinatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: KitW/KitW Genetic Background: B6.Cg-KitW/J
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MP:0011091 | complete prenatal lethality | "death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: KitW-s/Kit+ Genetic Background: involves: BRS
Allelic Composition: KitW-39H/KitW-39H Genetic Background: involves: BALB/cCrl * C3H/HeNCrl
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MP:0011092 | complete embryonic lethality | "death of all organisms of a given genotype in a population within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: Mybtm1Jof/Mybtm1Ssp Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Kittm1Rosay/Kittm1Rosay Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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MP:0011094 | complete embryonic lethality before implantation | "death of all organisms of a given genotype in a population between fertilization and implantation (Mus: E0 to less than E4.5)" [MGI:csmith] |
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Allelic Composition: Foxd2tm1Blh/Foxd2tm1Blh Genetic Background: involves: 129S6/SvEvTac * C57BL/6
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MP:0011098 | complete embryonic lethality during organogenesis | "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: KitW-3Bao/Kit+ Genetic Background: C57BL/6J-KitW-3Bao
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MP:0011099 | complete lethality throughout fetal growth and development | "death of all organisms of a given genotype in a population between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: KitW-s/KitW-s Genetic Background: involves: BRS
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: KitW-34J/KitW-34J Genetic Background: C57BL/6J-KitW-34J/J
Allelic Composition: KitW-35J/KitW-35J Genetic Background: C57BL/6J-KitW-35J/J
Allelic Composition: KitW-36J/KitW-36J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-37J Genetic Background: C57BL/6J-KitW-37J/J
Allelic Composition: KitW-38J/KitW-38J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-39J Genetic Background: C57BL/6J-KitW-39J/J
Allelic Composition: KitW-40J/KitW-40J Genetic Background: C57BL/6J-KitW-40J/J
Allelic Composition: KitW-39J/KitW-41J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-40J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-37J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-38J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-34J/KitW-39J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-42J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-39J/KitW-43J Genetic Background: involves: C57BL/6J
Allelic Composition: KitW-36H/KitW-36H Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-ct/KitW-ct Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: KitW-73J/KitW-73J Genetic Background: involves: DBA/2J
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MP:0011102 | partial embryonic lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the embryonic period prior to organogenesis (Mus: prior to E14)" [MGI:csmith] |
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Allelic Composition: KitW-v/KitW-v,Ly6atm1Pmf/Ly6atm1Pmf Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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MP:0011108 | partial embryonic lethality during organogenesis | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith] |
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Allelic Composition: KitW-42J/KitW-42J Genetic Background: C57BL/6J-KitW-42J/J
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MP:0011109 | partial lethality throughout fetal growth and development | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith] |
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Allelic Composition: KitW-42J/Kit+,X/SryAKR/J Genetic Background: involves: AKR/J * C57BL/6J
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MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: KitW/KitW-v Genetic Background: involves: C57BL/6J
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MP:0011178 | increased erythroblast number | "greater number of the nucleated precursor of erythrocytes" [MGI:csmith] |
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Allelic Composition: Kittm3.1Bsm/Kittm3.1Bsm Genetic Background: B6.129S1-Kittm3.1Bsm
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MP:0011188 | increased erythrocyte protoporphyrin level | "an accumulation of the intermediates of heme biosynthesis in red blood cells" [MGI:csmith] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0011277 | decreased tail pigmentation | "visually detectable dilution of pigment present on the tail surface" [MGI:csmith] |
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Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: C57BL/6J-KitW-2Btlr
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MP:0011279 | decreased ear pigmentation | "visually detectable dilution of pigment present in the outer ear" [MGI:csmith] |
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Allelic Composition: KitW-2Btlr/Kit+ Genetic Background: C57BL/6J-KitW-2Btlr
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MP:0011506 | glomerular crescent | "formation of a crescent-shaped (semi-lunar) glomerular lesion corresponding to extracapillary proliferation of Bowman s capsular epithelium and acquiring a fibroblast-like spindled morphology, possibly stimulated by release of fibrinogen from a ruptured glomerular basement membrane; epithelial crescents occur in aggressive forms of glomerulonephritis, may be accompanied by collagen and fibrin deposition and/or monocyte and macrophage proliferation, may protrude into Bowman s space, and ultimately compress and destroy the glomerular tuft" [MGI:anna] |
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Allelic Composition: Wrntm1Led/Wrn+ Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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MP:0011696 | absent mast cells | "any structural anomaly of a cell that is found in almost all tissues containing numerous basophilic granules and capable of releasing large amounts of histamine and heparin upon activation; progenitors leave bone marrow and mature in connective and mucosal tissue; mature mast cells are found in all tissues, except the bloodstream." [CL:0000097] |
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Allelic Composition: Fbn1Tsk/Fbn1+,KitW/KitW-v Genetic Background: involves: C57BL/6 * C57BL/10 * DBA/2 * WB/ReJ
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MP:0011967 | increased or absent threshold for auditory brainstem response | "increase in the value at which one or more sound frequencies or broadband clicks first elicits a recordable response generated by electrical activity of neurons in the ascending auditory system, or complete lack of a recordable response at any frequency or broadband click" [MGI:csmith] |
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Allelic Composition: KitWads/KitWads Genetic Background: C57BL/6J-KitWads
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MP:0012411 | increased granulosa cell tumor incidence | "greater than the expected number of neoplasms derived from somatic cells of the sex cord in the ovary a given population in a given time period" [http://orcid.org/0000-0001-5208-3432] |
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Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N
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MP:0013539 | increased ovary adenoma incidence | "greater than the expected number of a benign epithelial neoplasm with a glandular organization arising in the ovary, occurring in a specific population in a given time period" [MGI:Anna] |
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Allelic Composition: Cdkn1btm1Ako/Cdkn1btm1Ako,KitW-v/KitW-v Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Cdkn1btm1Ako/Cdkn1b+,KitW-v/KitW-v Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,KitW-v/KitW-v,Trp53tm1Brn/Trp53tm1Brn Genetic Background: involves: 129P2/OlaHsd * 129S7/SvEvBrd * C57BL/6J * FVB/N
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