| MP:0000351 | increased cell proliferation | "greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Oprm1tm1Uhl/Oprm1+
Genetic Background: either: B6.129S7-Oprm1tm1Uhl or (involves: 129S7/SvEvBrd)
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| MP:0000489 | abnormal large intestine morphology | "structural or developmental anomalies of the intestinum crassum " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm1Cti/Rettm1Cti
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm2(RET)Heno/Rettm2(RET)Jmi,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/Sv * C57BL/6 * CBA
|
| MP:0000495 | abnormal colon morphology | "malformation of the portion of the large intestine between the cecum and the rectum" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
|
| MP:0000496 | abnormal small intestine morphology | "structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm1Cti/Ret+
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0000519 | hydronephrosis | "dilation of the pelvis and calices of one or both kidneys" [J:56641] |
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Allelic Composition: Pstpip2cmo/Pstpip2cmo
Genetic Background: C.Cg-Pstpip2cmo/J
Allelic Composition: Rettm4(RET)Jmi/Rettm4(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0000520 | absent kidney | "missing paired organs that excrete urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49471] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Rettm1Cti/Rettm1Cti
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm13.1Jmi/Rettm13.1Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Allelic Composition: Rettm2(RET)Heno/Rettm3.1(Bcl2l1)Heno
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Rettm2.1Heno/Rettm2.1Heno
Genetic Background: involves: 129S/Sv * C57BL/6 * FVB/N
Allelic Composition: Rettm1Cos/Rettm1Cos
Genetic Background: involves: 129S/Sv * C57BL/6
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0000527 | abnormal kidney development | "anomalous differentiation of the paired organs responsible for urine secretion" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm1.2Pern/Rettm1.2Pern
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
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| MP:0000534 | abnormal ureter morphology | "anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0000538 | abnormal urinary bladder morphology | "malformation of the inflatable musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gstz1tm1Jmfc/Gstz1tm1Jmfc
Genetic Background: 129S4/SvJae-Gstz1tm1Jmfc
|
| MP:0000576 | clubbed feet | "congenital deformation of the feet; foot is plantarflexed, inverted and adducted" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified
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| MP:0000639 | abnormal adrenal gland morphology | "malformed endocrine glands located above the kidney responsible for hormone and epinephrine secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61190] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
|
| MP:0000681 | abnormal thyroid gland morphology | "anomalous structure of the endocrine gland located in the front and to the sides of the upper part of the trachea and which secretes thyroid hormone and calcitonin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
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| MP:0000746 | weakness | "state of being infirm or less strong than littermates" [J:45400] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0000909 | abnormal facial motor nucleus morphology | "malformation or disorganization of the group of motor neurons residing in the pons that innervate the muscles of facial expression" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Dapk1tm1Akc/Dapk1tm1Akc
Genetic Background: B6.129X1-Dapk1tm1Akc
|
| MP:0000939 | reduced motor neuron number | "fewer than normal numbers of cells that innervate an effector (muscle or glandular) tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm1Heno/Rettm1Heno
Genetic Background: Not Specified
Allelic Composition: Mnx1tm4(cre)Tmj/Mnx1+,Rettm2(RET)Heno/Rettm2(RET)Heno
Genetic Background: involves: C57BL/6 * SJL
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm11(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0000940 | abnormal motor neuron innervation | "misprojection or failure to bundle motor axons to an effector tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm1Heno/Rettm1Heno
Genetic Background: Not Specified
Allelic Composition: Mnx1tm4(cre)Tmj/Mnx1+,Rettm2(RET)Heno/Rettm2(RET)Heno
Genetic Background: involves: C57BL/6 * SJL
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm11(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
|
| MP:0000964 | small dorsal root ganglia | "reduced size of the dorsal root ganglia" [J:17123] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0001008 | abnormal sympathetic ganglia morphology | "malformed or absent groups of neuronal cell bodies of the autonomic nervous system" [J:18048] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0001014 | absent superior cervical ganglion | "missing group of neurons that is the largest of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:17792] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0001015 | small superior cervical ganglion | "reduced size of the group of neurons that is the largest of the ganglia of the sympathetic trunk; normally lies at the base of the skull and innervates the head and neck" [J:23882] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0001017 | abnormal stellate ganglion morphology | "malformation or absence of the group of neurons formed by the fusion of the inferior cervical and first thoracic ganglia" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0001025 | abnormal sympathetic neuron morphology | "malformation or anomalous development of any of the neurons of the part of the autonomic nervous system that innervates smooth muscle, cardiac muscle and glands and mediates the body s response to stressful situations" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0001044 | abnormal enteric nervous system morphology | "malformation or absence of the part of the autonomic nervous system that innervates the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm2.1Heno/Rettm2.1Heno
Genetic Background: involves: 129S/Sv * C57BL/6 * FVB/N
Allelic Composition: Rettm1Cos/Rettm1Cos
Genetic Background: involves: 129S/Sv * C57BL/6
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| MP:0001045 | abnormal enteric ganglia morphology | "any strucutural anomaly or deformity of the groups of nerve cell bodies associated with the enteric neurons" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm5(RET)Vpa/Rettm5(RET)Vpa
Genetic Background: either: 129S1/Sv-Rettm5(RET)Vpa or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: Rettm1Cti/Rettm1Cti
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Allelic Composition: Rettm2(RET)Heno/Rettm1Cos,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/Sv * C57BL/6 * CBA
Allelic Composition: Rettm1Cos/Rettm1Cos
Genetic Background: involves: 129S/Sv * C57BL/6
Allelic Composition: Rettm2.1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129S/Sv * C57BL/6 * FVB/N
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| MP:0001046 | abnormal enteric neuron morphology | "malformed or absent neurons that innervate the esophagus, stomach, small and large bowel" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gdnftm1Rosl/Gdnf+,Nrtntm1Jmi/Nrtntm1Jmi
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
Allelic Composition: Rettm1Cti/Ret+
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm13.1Jmi/Rettm13.1Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
Allelic Composition: Rettm1Heno/Rettm2(RET)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Rettm1Heno/Rettm3.1(Bcl2l1)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Baxtm1Sjk/Baxtm1Sjk,Rettm1Heno/Rettm3.1(Bcl2l1)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
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| MP:0001048 | absent enteric neurons | "missing neurons that innervate the esophagus, stomach, small and large bowel" [Principles of Neural Science:ISBN 0-8385-8034-3, J:49471] |
Show
Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Rettm1Cti/Rettm1Cti
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm13.1Jmi/Rettm13.1Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Allelic Composition: Rettm2(RET)Heno/Rettm3.1(Bcl2l1)Heno
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Rettm2(RET)Jmi/Rettm3.1(Bcl2l1)Heno
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0001052 | abnormal muscle innervation | "malfomation or misprojection of sensory or motor nerves to targets in muscle" [J:75958] |
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Allelic Composition: Hoxd11tm1Mrc/Hoxd11tm1Mrc
Genetic Background: Not Specified
Allelic Composition: Rettm1Kln/Rettm1Kln,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Allelic Composition: Epha4Gt(PST038)Byg/Epha4Gt(PST038)Byg,Rettm1.1Kln/Rettm1.1Kln
Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J
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| MP:0001053 | abnormal neuromuscular synapse | "malformed or absent membrane to membrane contact of a motor axon and a muscle myofiber resulting in aberrant transmission of nerve impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159, J:47439] |
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Allelic Composition: Dapk1tm1Akc/Dapk1tm1Akc
Genetic Background: B6.129X1-Dapk1tm1Akc
Allelic Composition: Rettm1.2Pern/Rettm1.2Pern
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
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| MP:0001154 | seminiferous tubule degeneration | "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
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| MP:0001155 | arrest of spermatogenesis | "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271] |
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Allelic Composition: Nhlh1tm1Thbr/Nhlh1tm1Thbr,Nhlh2tm1Thbr/Nhlh2tm1Thbr
Genetic Background: involves: 129S4/SvJae
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| MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: Nhlh1tm1Thbr/Nhlh1tm1Thbr,Nhlh2tm1Thbr/Nhlh2tm1Thbr
Genetic Background: involves: 129S4/SvJae
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| MP:0001176 | abnormal lung development | "malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
Show
Allelic Composition: Rettm1Heno/Rettm2(RET)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0001270 | distended abdomen | "abdomen appears curved outward or swollen; can be due to skeletal axial defects, enlarged visceral organs or megacolon" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0001402 | hypoactivity | "reduced movement from one place to another" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:64289] |
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Allelic Composition: Rettm13.1Jmi/Rettm13.1Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N
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| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Kif1bpem2Hmy/Kif1bpem2Hmy
Genetic Background: Not Specified
Allelic Composition: Kif1bpem1Hmy/Kif1bpem1Hmy,Rettm1Jmi/Ret+
Genetic Background: involves: 129X1/SvJ
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| MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
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| MP:0002050 | pheochromocytoma | "a benign neoplasm derived from adrenal medullary cells; usually associated with hypertension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm2.1Cos/Rettm2.1Cos
Genetic Background: involves: 129S1/Sv * C57BL/6J
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| MP:0002058 | neonatal lethality | "death of animal within one day after birth" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nhlh1tm1Thbr/Nhlh1tm1Thbr,Nhlh2tm1Thbr/Nhlh2tm1Thbr
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0002135 | abnormal kidney morphology | "abnormal development of the kidney resulting in structural abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm1Cos/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Nhlh1tm1Thbr/Nhlh1tm1Thbr,Nhlh2tm1Thbr/Nhlh2tm1Thbr
Genetic Background: involves: 129S4/SvJae
Allelic Composition: Rettm1(RET)Vpa/Rettm1(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm4(RET)Vpa/Rettm4(RET)Vpa
Genetic Background: either: 129S1/Sv-Rettm4(RET)Vpa or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: Rettm1(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm5(RET)Jmi/Rettm5(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm6(RET)Jmi/Rettm6(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm14(Gfra1)Jmi/Ret+
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Gfra1tm3Jmi/Gfra1tm3Jmi,Rettm14(Gfra1)Jmi/Ret+
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Rettm1.1Pern/Rettm1.1Pern
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Allelic Composition: Rettm2(cre/ERT2)Ddg/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm1.1Vlcg/Rettm1.1Vlcg
Genetic Background: involves: 129S6/SvEvTac * C57BL/6NTac
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| MP:0002184 | abnormal innervation | "the malformation, misprojection or malfunction of the connection of nerve fibers with a target" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0002269 | muscular atrophy | "a wasting of muscle tissue resulting in a derangement of the muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm11(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0002286 | cryptorchism | "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0002705 | dilated renal tubules | "enlarged lumens of the loops of Henle and/or collecting ducts of the kidney" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0002769 | abnormal vas deferens morphology | "malformation of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0002882 | abnormal neuron | "anomaly in the functional cells of the nervous system that receive, conduct, and transmit impulses " [MeSH:National Library of Medicine - Medical Subject Headings, 2003] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Allelic Composition: Rettm1.1Ddg/Rettm1.1Ddg
Genetic Background: involves: 129
Allelic Composition: Islr2tm1.1Ddg/Islr2tm1.1Ddg,Rettm1.1Ddg/Ret+
Genetic Background: involves: 129S6/SvEvTac * BALB/cJ * C57BL/6
Allelic Composition: Islr2tm1.1Ddg/Islr2tm1.1Ddg,Rettm1.1Ddg/Rettm1.1Ddg
Genetic Background: involves: 129S6/SvEvTac * BALB/cJ * C57BL/6
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| MP:0002926 | aganglionic megacolon | "extreme dilation of the colon due to defects in innervation from the ganglia, or absence of the ganglia of the myenteric plexus" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Allelic Composition: Rettm1Cos/Rettm2(RET)Jmi
Genetic Background: involves: 129S/Sv * C57BL/6
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| MP:0002961 | abnormal axon guidance | "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Rettm1Kln/Rettm1Kln,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Allelic Composition: Lhx1tm1Tmj/Lhx1+,Rettm1Kln/Rettm1Kln,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J * SJL
Allelic Composition: Epha4Gt(PST038)Byg/Epha4Gt(PST038)Byg,Rettm1.1Kln/Rettm1.1Kln
Genetic Background: involves: 129/Sv * BALB/c * C57BL/6 * CBA/J
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| MP:0002989 | small kidney | "reduced physical bulk one or both of the organs responsible for urine secretion" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm1Cos/Ret+,Wnt11tm1Amc/Wnt11+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1
Allelic Composition: Rettm1Cos/Ret+,Wnt11tm1Amc/Wnt11tm1Amc
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm5(RET)Vpa/Rettm5(RET)Vpa
Genetic Background: either: 129S1/Sv-Rettm5(RET)Vpa or (involves: 129S1/Sv * C57BL/6J)
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| MP:0003082 | abnormal gastrocnemius morphology | "anomaly in the the two-headed large muscle of the posterior portion of the lower hindleg, the most superficial of the calf muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm1Heno/Rettm1Heno
Genetic Background: Not Specified
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| MP:0003203 | increased neuron apoptosis | "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Rettm2.1Heno/Rettm2.1Heno
Genetic Background: involves: 129S/Sv * C57BL/6 * FVB/N
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| MP:0003204 | decreased neuron apoptosis | "decrease in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission] |
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Allelic Composition: Rettm2(RET)Heno/Rettm3.1(Bcl2l1)Heno
Genetic Background: involves: 129/Sv * C57BL/6
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| MP:0003244 | loss of dopaminergic neurons | "loss of the neurons that utilize dopamine as a neurotransmitter, commonly due to an apoptotic event" [RGD:Rat Genome Database submission] |
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Allelic Composition: Rettm1Kln/Rettm1Kln,Slc6a3tm1(cre)Xz/Slc6a3+
Genetic Background: involves: 129S1/Sv
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| MP:0003289 | abnormal intestinal peristalsis | "altered intestinal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls of the bowel that move bowel contents forward" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0003290 | hypoperistalsis | "reduced intestinal movement characterized by waves of alternate circular contraction and relaxation of the muscular walls of the bowel that move bowel contents forward" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * C57BL/6
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| MP:0003358 | abnormal hypaxial muscle morphology | "malformation of the muscles of the limbs" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm1Heno/Rettm1Heno
Genetic Background: Not Specified
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm11(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0003446 | renal hypoplasia | "decreased cell number in the kidney leading to reduced size" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm1Cos/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0003496 | thyroid adenoma | "appearance of benign neoplasms in the thyroid gland" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
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| MP:0003498 | thyroid hyperplasia | |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm2.1Cos/Ret+
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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| MP:0003585 | large ureter | "increased size or length of the tube that conducts the urine from the renal pelvis to the bladder" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003586 | ureter dilation | "abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Pstpip2cmo/Pstpip2cmo
Genetic Background: C.Cg-Pstpip2cmo/J
Allelic Composition: Rettm4(RET)Jmi/Rettm4(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003587 | ureter obstruction | "any impediment, blockage, or reversal of the normal flow of the urine towards the bladder" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003588 | ureter stenosis | "abnormal narrowing or constriction of the ureter" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003600 | ectopic kidney | |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003604 | single kidney | |
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Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0003613 | abnormal kidney medulla development | |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003670 | dilated glomerular capsule | "an expansion in volume of the expanded beginning of a nephron that contains the glomerulus" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:91499] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0003672 | abnormal ureter development | "anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0003675 | kidney cysts | "abnormal membranous sacs in any portion of the pair of organs responsible for urine secretion" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm5(RET)Vpa/Rettm5(RET)Vpa
Genetic Background: either: 129S1/Sv-Rettm5(RET)Vpa or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0003685 | abnormal cardiac ganglion morphology | "any anomaly of the parasympathetic ganglia of the cardiac plexus between the arch of the aorta and the bifurcation of the pulmonary artery " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0003722 | absent ureter | "missing the tube that conducts the urine from the renal pelvis to the bladder" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0003793 | abnormal submandibular gland morphology | "any structural malformation of either of the large major salivary glands situated beneath the mandible" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0003866 | abnormal defecation | "anomaly in the production and excretion of feces" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm1Heno/Rettm3.1(Bcl2l1)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0003868 | abnormal feces composition | "increase or decrease in the amount of compunds normally found in the feces (fat, protein etc) or presence of material not normally seen in the feces" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm1Heno/Rettm3.1(Bcl2l1)Heno,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * CBA
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0003918 | decreased kidney weight | "reduced heft of the organs responsible for urine secretion" [RGD:Rat Genome Database submission] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0004002 | abnormal jejunum morphology | "malformation of the portion of the small intestine that extends from the duodenum to the ileum" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0004069 | abnormal muscle spindle morphology | "anomalous structure of the sensory organs in muscle that are involved in the stretch reflex" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3] |
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Allelic Composition: Dtnbp1sdy-Btlr/Dtnbp1sdy-Btlr
Genetic Background: C57BL/6J-Dtnbp1sdy-Btlr
Allelic Composition: Rettm1Heno/Rettm1Heno
Genetic Background: Not Specified
Allelic Composition: Rettm12(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm11(RET)Jmi/Rettm12(RET)Jmi
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004281 | abnormal hypoglossal nucleus morphology | "any structural anomaly of the group of motor neurons throughout most of the length of the medulla oblongata that give rise to the motor fibers of the hypoglossal nerve" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Dapk1tm1Akc/Dapk1tm1Akc
Genetic Background: B6.129X1-Dapk1tm1Akc
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| MP:0004505 | decreased renal glomerulus number | "reduced number of the capillary loops of the kidney that normally function as a filtration unit" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
Allelic Composition: Rettm5(RET)Vpa/Rettm5(RET)Vpa
Genetic Background: either: 129S1/Sv-Rettm5(RET)Vpa or (involves: 129S1/Sv * C57BL/6J)
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0004754 | abnormal kidney collecting duct | "any structural anomaly of the duct that drains fluid from the nephron and either allows bodily reabsorbtion of water or allows the fluid to drain to the bladder via the ureter; the collecting duct system also maintains acid-base homeostasis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0004936 | abnormal ureteric bud branching morphogenesis | "partial or complete failure of the ureteric bud to repeatedly divide into lobules during development of the kidney" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Cos/Ret+,Wnt11tm1Amc/Wnt11tm1Amc
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ * MF1
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
Allelic Composition: Rettm1Jmi/Ret+
Genetic Background: involves: 129X1/SvJ
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| MP:0004970 | kidney atrophy | "wasting of the kidney due to injury or disease, resulting in reduced size" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0005264 | glomerulosclerosis | "hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0005325 | abnormal glomerulus | "anomalous structure of the capillary loops of the kidney that normally function as a filtration unit" [J:57971, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0005445 | abnormal neurotransmitter release | "aberration in the secretion of endogenous signaling molecules normally secreted by neurons that alter the behavior of neurons or effector cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Gdnftm1Rosl/Gdnf+,Nrtntm1Jmi/Nrtntm1Jmi
Genetic Background: involves: 129S2/SvPas * 129X1/SvJ * C57BL/6
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| MP:0005584 | abnormal enzyme/coenzyme activity | "altered ability of any of these proteins, or their cofactors, to act as catalysts to induce chemical changes in other substances" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
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| MP:0006032 | abnormal ureteric bud morphology | "anomaly in the formation or development of the ureteric bud that with the metanephric mesenchyme gives rise to the kidneys " [smb:Susan M Bello, Mouse Genome Informatics Curator, J:57313:] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0008289 | abnormal adrenal medulla morphology | "any structural anomaly of the inner portion of the adrenal gland that consists mainly of chromaffin cells which produce, store and secrete neurotransmitters such as epinephrine and norepinephrine" [MESH:A06.407.071.265, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
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| MP:0008298 | adrenergic chromaffin cell hyperplasia | "an increase in the number of the cells of the medulla of the adrenal gland that are innervated by the splanchnic nerve and that are responsible for epinephrine secretion" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm2.1Cos/Ret+
Genetic Background: involves: 129S1/Sv * C57BL/6J * FVB/N
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| MP:0008299 | adrenal cortical hyperplasia | "overdevelopment of the thick outer layer of the adrenal gland that produces and secretes steroid hormones, usually due to an increase in the number of cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
Allelic Composition: Rettm1Giro/Ret+
Genetic Background: 129.129P2-Rettm1Giro
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| MP:0008312 | abnormal sympathetic postganglionic fiber | "any structural anomaly of any or all of the noradrenergic and some adrenergic axonal fibers projecting from a sympathetic ganglion to an effector organ" [MESH:A08.663.542.075.800, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0008313 | abnormal parasympathetic postganglionic fiber | "any structural anomaly of any or all of the cholinergic axonal fibers projecting from a parasympathetic ganglion to an effector organ" [MESH:A08.663.542.100.700, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0008314 | abnormal pterygopalatine ganglion morphology | "any structural anomaly of the small parasympathetic ganglion that supplies nerve fibers to the lacrimal, nasal, palatine and pharyngeal glands" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
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| MP:0008316 | abnormal prevertebral ganglion morphology | "any structural anomaly of the sympathetic ganglia located in front of the vertebral column and are associated with the major branches of the abdominal aorta; these include the celiac, aorticorenal, superior and inferior mesenteric ganglia" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
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| MP:0008415 | abnormal neurite morphology | "any structural anomaly of a neuronal process, either a dendrite or an axon in vivo, or a filamentous projection from a neuron such as is seen in tissue culture" [PMID:12951572] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0008487 | abnormal mesonephros morphology | "any structural anomaly of the excretory organ of the embryo, collective Wolffian tubules, which forms the urogenital fold from which the reproductive organs develop" [MESH:A16.254.500] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0009483 | enlarged ileum | "increased size of the portion of the small intestine that extends from the jejunum to the colon" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
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| MP:0009485 | distended ileum | "an expansion in the volume of the portion of the small intestine that extends from the jejunum to the colon, as by stretching or distention" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
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| MP:0009843 | decreased neural crest cell number | "reduction in the number of ransient and migratory group of cells that emerge from the dorsal region of the neural tube and disperse to many peripheral locations to form various tissues of the adult" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm2(RET)Heno/Rettm2(RET)Jmi,Tg(CAG-cre/Esr1*)5Amc/0
Genetic Background: involves: 129S/Sv * C57BL/6 * CBA
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| MP:0009857 | absent kidney cortex | "absence of the outer area of the kidney, which contains the glomerular capillaries and the capsula glomeruli that enclose it" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0009937 | abnormal neuron differentiation | "abnormal growth or development of the cells of the nervous system that receive, conduct, and transmit impulses" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
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| MP:0010149 | abnormal synaptic dopamine release | "aberrant secretion across synapses of the catecholamine neurotransmitter and neurohormone, derived from tyrosine and the precursor to norepinephrine and epinephrine; functions as a neurotransmitter in the brain and as a hormone to inhibit the release of prolactin from the anterior lobe of the pituitary" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm1Kln/Rettm1Kln,Slc6a3tm1(cre)Xz/Slc6a3+
Genetic Background: involves: 129S1/Sv
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| MP:0010362 | increased ganglioneuroma incidence | "greater than the expected number of a benign neoplasm composed of mature ganglionic neurons in a given population in a given time period; cells may be scattered singly or in clumps within a relatively abundant and dense stroma of neurofibrils and collagenous fibers" [MPATH:375] |
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Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
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| MP:0010980 | ectopic ureteric bud | "ureteric bud(s) are not located in the normal or expected position" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0010981 | abnormal branching involved in ureteric bud morphogenesis | "anomaly in the process in which the branching structure of the ureteric bud is generated and organized" [GO:0001658] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0010982 | abnormal ureteric bud elongation | "any anomaly in the process in which a ureteric bud grows along its axis" [GO:0060677] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0010983 | abnormal ureteric bud invasion | "any anomaly in the process in which the ureteric bud grows into the metanephric mesenchyme, and contributes to the formation of the metanephros" [PMID:19828308] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0010984 | abnormal metanephric mesenchyme morphology | "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing metanephros; interactions between the ureteric bud and the metanephric mesenchyme leads to the initiation of outgrowth and repetitive branching of the UB that ultimately generates the definitive renal collecting system and induces formation of renal vesicles from the mesenchyme tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:19828308] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0010985 | abnormal kidney mesenchyme morphology | "any structural anomaly of the embryonic connective tissue made up of loosely aggregated mesenchymal cells, supported by interlaminar jelly, in the developing kidney" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0011085 | complete postnatal lethality | "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Stat5btm1Mam/Stat5btm1Mam,Tg(Wap-cre)11738Mam/0
Genetic Background: involves: 129S6/SvEvTac * Black Swiss
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| MP:0011086 | partial postnatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith] |
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Allelic Composition: Rettm1Ddg/Rettm1Ddg,H2afvTg(Wnt1-cre)11Rth/0
Genetic Background: involves: 129 * C57BL/6 * C57BL/6J * CBA/J
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
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| MP:0011087 | complete neonatal lethality | "death of all organisms of a given genotype in a population within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm2Cos/Rettm2Cos
Genetic Background: involves: 129S1/Sv
Allelic Composition: Rettm1Jmi/Rettm1Jmi
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Rettm1Cti/Rettm1Cti
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Rettm1Giro/Rettm1Giro
Genetic Background: involves: 129/Sv * 129P2/OlaHsd * C57BL/6
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| MP:0011089 | complete perinatal lethality | "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith] |
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Allelic Composition: Rettm1.2Pern/Rettm1.2Pern
Genetic Background: involves: 129P2/OlaHsd * BALB/c * C57BL/6 * SJL
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| MP:0011110 | partial preweaning lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith] |
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Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Pax2tm1Pgr/Pax2+,Rettm1Cos/Ret+
Genetic Background: involves: 129S/SvEv * 129S1/Sv * 129X1/SvJ
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| MP:0011368 | increased kidney apoptosis | "increase in the number of cells of the kidney undergoing programmed cell death" [MGI:anna] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0011386 | increased metanephric mesenchyme apoptosis | "increase in the number of cells of the metanephric mesenchyme (MM) undergoing programmed cell death; usually due to failure of MM cells to interact with the ureteric bud (UB) tips after UB invasion" [MGI:anna] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0011402 | renal cast | "any of the various casts formed from gelled protein precipitated in the distal convoluted tubules and collecting ducts of nephrons and molded to the tubular or duct lumen which dislodge and pass into the urine; types named for their constituent material include acellular casts (e.g. granular, hyaline, waxy, or fatty casts) and cellular casts (e.g. red or white blood cell casts)" [MGI:anna] |
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Allelic Composition: Rettm3.1(RET)Jmi/Ret+
Genetic Background: Not Specified
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| MP:0011407 | absent nephrogenic zone | "absence of the region found at the periphery of the developing metanephros within which the metanephric mesenchyme aggregates around the tips of the ureteric tree to form the nephrons;in rodents including mice, this region normally persists for a few days postnatally, although it is lost in humans by 36 weeks of gestation" [PMID:17452023] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm9(RET)Jmi/Rettm9(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0011410 | ectopic testis | "one or both of the testes located outside the normal pathway of descent into the scrotum" [MGI:anna] |
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Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0011438 | absent kidney medulla | "failure of the inner portion of the kidney, normally consisting of the renal pyramids, to form" [MGI:anna] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0011727 | ectopic ovary | "appearance of an ovary in a region where it is not normally found (topographical anomaly)" [MGI:csmith] |
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Allelic Composition: Rettm11(RET)Jmi/Rettm11(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
Allelic Composition: Rettm8(RET)Jmi/Rettm8(RET)Jmi
Genetic Background: involves: 129X1/SvJ * 129S1/Sv * C57BL/6
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| MP:0011797 | blind ureter | "a ureter ending in a blind-ended segment or pouch" [MGI:anna] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0012171 | oligohydramnios | "presence of an abnormally low amniotic fluid volume in the amniotic sac; the opposite of polyhydramnios" [MGI:anna] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
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| MP:0013001 | abnormal enteric neural crest cell morphology | " any structural anomaly of the neural crest cells that arise predominantly from the vagal region of the neural tube (vagal neural crest), adjacent to somites 1-7 and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; neural crest cells are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans)" [MGI:anna, PMID:17514199] |
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Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
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| MP:0013003 | absent enteric neural crest cell | "absence or loss of the neural crest cells that arise predominantly from the vagal region of the neural tube (vagal neural crest), adjacent to somites 1-7 and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut" [MGI:anna, PMID:17514199] |
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Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm3(RET)Vpa/Rettm3(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd * C57BL/6J
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| MP:0013006 | abnormal enteric neural crest cell migration | "any anomaly in the migratory path or behavior of the neural crest cells (NCCs) that arise predominantly from the vagal (neck) region of the neural tube (vagal neural crest), adjacent to somites 1-7, and migrate rostro-caudally along the gastrointestinal tract to form two ganglionated plexuses of neurons and glial cells that comprise the enteric nervous system (ENS); a smaller proportion of ENCCs come from the sacral neural crest, caudal to somite 28, and migrate caudo-rostrally to colonize the distal gut; NCCs are termed enteric neural crest-derived cells upon entering the foregut at E9-9.5 in mice (after 4 weeks gestation in humans) and the colonization process is complete by E15.5 (after 7 weeks gestation in humans)" [MGI:anna, PMID:17514199] |
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Allelic Composition: Ptger4tm1Bhk/Ptger4tm1Bhk
Genetic Background: involves: 129P2/OlaHsd * 129S/SvEv
Allelic Composition: Rettm2(RET)Vpa/Rettm2(RET)Vpa
Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Rettm3Cos/Rettm3Cos
Genetic Background: involves: 129S1/Sv * FVB/N
Allelic Composition: Rettm2(RET)Jmi/Rettm3.1(Bcl2l1)Heno
Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Rettm1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Rettm2.1Heno/Rettm2(RET)Jmi
Genetic Background: involves: 129S/Sv * C57BL/6 * FVB/N
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