Manteia

ID	Phenotype	Definition	Genetic BG
MP:0000091	short premaxilla	"reduced length of the anterior and interior portion of the maxilla" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000097	short maxilla	"reduced length of the upper jaw bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000102	abnormal nasal bone morphology	"malformed elongated rectangular bone that forms part of the nasal bridge" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0000105	defective ossification of basisphenoid	"abnormal formation of the bone at the base of the sphenoid bone; arises from an ossification center independent of the remainder of the sphenoid bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000107	abnormal frontal bone morphology	"malformed bone forming the forehead and part of the eye orbit" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:17489]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Zfp950^{Gt(ROSA)76Sor}/Zfp950^{Gt(ROSA)76Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000108	midline facial cleft	"incomplete merging or fusion of the tissues normally uniting to form the face" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified Allelic Composition: Pdgfra^{tm10(Pdgfra/tor)Sor}/Pdgfra^{tm10(Pdgfra/tor)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000109	abnormal parietal bone morphology	"malformed curved bone forming part of the vault of the cranium" [J:17489]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000111	cleft palate	"congenital fissure of the tissues normally uniting to form the palate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]	Show Allelic Composition: Gpx4^tm1Yana/Gpx4^tm1Yana Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000149	abnormal scapula morphology	"malformation of either or both of the large, flat bones of the back part of the shoulder" [J:13049]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000150	abnormal rib morphology	"malformed bones forming the bony wall of the chest" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:50311]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000153	rib bifurcation	"forking or division of ribs, may be a result of partial rib fusions" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000154	rib fusion	"appearance of one or more ribs as a single structure" [J:62022, J:62023]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000157	abnormal sternum morphology	"malformed long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:19212]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000158	absent sternum	"missing long flat bone of the chest; articulates with clavicle and first seven rib pairs" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:62577]	Show Allelic Composition: Gpx4^tm1Yana/Gpx4^tm1Yana Genetic Background: involves: C57BL/6 * CBA
MP:0000351	increased cell proliferation	"greater than the normal growth and reproduction of similar cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0000445	short snout	"reduced length of the anterior facial part of the muzzle" [J:53370]	Show Allelic Composition: Abca1^tm1Jdm/Abca1⁺ Genetic Background: DBA/1LacJ-Abca1^tm1Jdm Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0000470	abnormal stomach morphology	"malformation of the sac-like structure of the digestive canal between the esophagus and the small intestine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000494	abnormal cecum morphology	"malformation of the large sac at the ileum and large intestine junction" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000496	abnormal small intestine morphology	"structural or developmental anomalies of the intestinum tenue " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000519	hydronephrosis	"dilation of the pelvis and calices of one or both kidneys" [J:56641]	Show Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000534	abnormal ureter morphology	"anomalous structure of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0000562	polydactyly	"greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0000639	abnormal adrenal gland morphology	"malformed endocrine glands located above the kidney responsible for hormone and epinephrine secretion" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61190]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0000704	abnormal thymus development	"anomaly in the formation and/or differentiation of the thymus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0000706	small thymus	"reduced size of the thymus" [J:36561, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:31167]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0000737	abnormal myotome development	"malformation of or absence of the part of the somite that develops into the musculature" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:29279]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000745	tremors	"repetitive, cyclical movements of the body or a body part; usually involuntary, but can also manifest in response to an attempt at movement" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000757	herniated abdominal wall	"protrusions through and/or into the abdominal wall often resulting in the extrusion of viscera" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:40203]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000920	abnormal myelination	"atypical or altered myelination in axon sheaths" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm6Sor/Pdgfra^tm6Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm6Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000924	absent roof plate	"missing thin layer of the embryonic neural tube connecting the dorsal side" [J:41814]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000928	incomplete cephalic closure	"arrest of the fusion of the cephalic neural folds" [J:12622]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000929	open neural tube	"incomplete invagination and fusion of the neuroepithelial layer in early development" [MGI:CLS, J:53370, J:62571]	Show Allelic Composition: Gpx4^tm1Yana/Gpx4^tm1Yana Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000930	wavy neural tube	"undulations in the embryonic neural tube" [J:37888]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000953	abnormal oligodendrocyte morphology	"anomalous structure, number or composition of the neuroglia of the central nervous system that form the insulating myelin sheath of axons in the CNS" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm6Sor/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0000954	reduced oligodendrocyte progenitor number	"fewer cells that differentiate into a type of glial cell in the central nervous system" [J:15108]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm6Sor/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001121	uterine hypoplasia	"reduced size of the uterus due to decreased cell number" [J:45065]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001126	abnormal ovary morphology	"malformed female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Slc14a1^tm1Ask/Slc14a1^tm1Ask Genetic Background: involves: C57BL/6J * CD-1 Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001127	small ovary	"reduced size of the female reproductive gland containing the germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Slc14a1^tm1Ask/Slc14a1^tm1Ask Genetic Background: involves: C57BL/6J * CD-1 Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001131	abnormal ovarian follicles	"malformed or absent sac-like structure in the ovary which surrounds an ovum" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33042]	Show Allelic Composition: Slc26a9^tm1Sole/Slc26a9⁺ Genetic Background: involves: 129S/SvEv
MP:0001134	absent corpora lutea	"missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782]	Show Allelic Composition: Slc14a1^tm1Ask/Slc14a1^tm1Ask Genetic Background: involves: C57BL/6J * CD-1
MP:0001146	abnormal testis morphology	"anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Slc26a9^tm1Sole/Slc26a9⁺ Genetic Background: involves: 129S/SvEv Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001147	small testis	"reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001175	abnormal lung morphology	"malformed organ of respiration" [J:35802]	Show Allelic Composition: Pdgfa^tm1Cbet/Pdgfa^tm2Cbet,Pdgfra^{tm11(EGFP)Sor}/Pdgfra⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6
MP:0001176	abnormal lung development	"malformation or arrest of differentiation of the organs of respiration" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54931]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0001178	pulmonary hypoplasia	"reduced size of the respiratory organ due to incomplete development of all or part of the organ " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Pathology , 2nd edition:ISBN 0-397-51047-0]	Show Allelic Composition: Ndufs4^tm1.1Rpa/Ndufs4^tm1.1Rpa Genetic Background: involves: 129S4/SvJaeSor
MP:0001198	tight skin	"skin has a taut, stretched appearance" [J:65038]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0001218	thin epidermis	"reduced thickness of the superficial epithelial portion of the skin" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001262	decreased body weight	"lower than normal average weight " [J:61295]	Show Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0001265	reduced body size	"smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]	Show Allelic Composition: Ube3a^tm1Alb/Ube3a⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0001575	cyanosis	"a dark bluish or purple skin discoloration resulting from deficient oxygenation of the blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60159]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0001577	anemia	"less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]	Show Allelic Composition: Zfp950^{Gt(ROSA)76Sor}/Zfp950⁺,Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^{tm1.1(cre/Esr1)Nshk}/Pdgfra⁺,Runx1^tm1Medv/Runx1^tm1Medv Genetic Background:* involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj
MP:0001622	abnormal vasculogenesis	"aberrant process of the initial establishment of the vascular network " [J:67296, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Abca1^tm1Jdm/Abca1⁺ Genetic Background: DBA/1LacJ-Abca1^tm1Jdm
MP:0001634	internal hemorrhage	"blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001690	failure of somite differentiation	"disorganized or absent somite tissue or somite pattern in development" [J:25248]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001698	reduced embryo size	"smaller proportions of embryo compared to littermates" [J:61790]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001699	enlarged embryo size	"larger proportions of embryo compared to littermates" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0001701	incomplete embryo turning	"arrest of the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [J:62571]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001712	abnormal placental development	"malformed or incomplete differentiation of the organ of metabolic exchange between the fetus and mother" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61790]	Show Allelic Composition: Maff^tm1.1Jeng/Maff^tm1.1Jeng Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1 Allelic Composition: Pdgfra^{tm11(EGFP)Sor}/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001785	edema	"an accumulation of an excessive amount of watery fluid in cells or intercellular tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:54065]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0001786	skin edema	"accumulation of an excessive amount of fluid in the skin" [J:65039]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001787	pericardial edema	"accumulation of watery fluid in the pericardial sac of the heart" [J:52597]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0001823	thymus hypoplasia	"small size due to reduced cell number in the thymus" [J:23255]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0001914	hemorrhage	"loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0001925	male infertility	"inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]	Show Allelic Composition: Slc14a1^tm1Ask/Slc14a1^tm1Ask Genetic Background: involves: C57BL/6J * CD-1 Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001926	female infertility	"inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]	Show Allelic Composition: Slc14a1^tm1Ask/Slc14a1^tm1Ask Genetic Background: involves: C57BL/6J * CD-1 Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Sgpl1^{Gt(ROSA)78Sor}/Sgpl1^{Gt(ROSA)78Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0001953	respiratory failure	"cessation of or failure to commence breathing" [MGI:cls, J:60159]	Show Allelic Composition: Ube3a^tm1Alb/Ube3a⁺ Genetic Background: involves: 129S7/SvEvBrd
MP:0001958	emphysema	"lung disease characterized by increased size of terminal bronchioles with destructive changes in their walls and reduction in number" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:33629]	Show Allelic Composition: Ube3a^tm1Alb/Ube3a⁺ Genetic Background: involves: 129S7/SvEvBrd Allelic Composition: Pdgfa^tm1Cbet/Pdgfa^tm2Cbet,Pdgfra^{tm11(EGFP)Sor}/Pdgfra⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6
MP:0002032	sarcoma	"connective tissue neoplasm associated with the proliferation of mesodermal cells" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:58877]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL
MP:0002064	seizures	"sudden and often acute manifestation of epileptic attack, sometimes convulsive" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0002080	prenatal lethality	"death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gclc^tm1Tdal/Gclc^tm1Tdal,Speer6-ps1^{Tg(Alb-cre)21Mgn}/Speer6-ps1⁺ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * DBA
MP:0002082	postnatal lethality	"premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Abca1^tm1Jdm/Abca1⁺ Genetic Background: DBA/1LacJ-Abca1^tm1Jdm
MP:0002083	premature death	"death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0002113	abnormal skeleton development	"anomalous differentiation or remodeling of bone tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0002151	abnormal neural tube morphology/development	"anomalous structure of or development of the embryonic neural tube resulting in structural anomaly" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0002169	no phenotype detected	"normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Ckb^tm1Bew/Ckb^tm1Bew,Ckmt1^tm2Bew/Ckmt1^tm2Bew Genetic Background: involves: 129P2/OlaHsd * C57BL/6
MP:0002192	hydrops fetalis	"an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Gpx4^tm1Yana/Gpx4^tm1Yana Genetic Background: involves: C57BL/6 * CBA
MP:0002270	abnormal alveoli morphology	"any structural anomaly of the outpouching of the respiratory system where gas exchange occurs" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfa^tm1Cbet/Pdgfa^tm2Cbet,Pdgfra^{tm11(EGFP)Sor}/Pdgfra⁺ Genetic Background: involves: 129S1/Sv * 129S4/SvJaeSor * 129X1/SvJ * C57BL/6
MP:0002633	persistent truncus arteriosis	"complete failure of the common arterial trunk opening out of both ventricles to divide into the aorta and pulmonary artery during development" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0002680	decreased number of corpora lutea	"fewer than normal numbers of yellow endocrine body formed in the ovary after follicle rupture in a given oestrus cycle" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0002683	delayed fertility	"ability to produce live offspring occuring at a later than expected age" [llw2:Linda Washburn , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0002687	oligozoospermia	"reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0002722	abnormal immune system organ morphology	"anomalous structure/organization or development of lymphoid organs" [cwg:Carroll W. Goldsmith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0002768	small adrenal glands	"reduced size of endocrine glands located above the kidneys responsible for hormone and epinephrine secretion" [J:78062]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0002990	short ureter	"reduced length of the tube that conducts the urine from the renal pelvis to the bladder" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0003047	abnormal thoracic vertebrae morphology	"malformation of any or all of the thirteen bony segments of the spine located anterior to the lumbar vertebrae and posterior to the cervical vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003048	abnormal cervical vertebrae morphology	"malformation of any or all of the seven bony segments of the spine located anterior to the thoracic vertebrae" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003054	spina bifida	"common congenital midline defect of fusion of the vertebral arch" [MeSH:National Library of Medicine - Medical Subject Headings, 2003]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^{tm10(Pdgfra/tor)Sor}/Pdgfra^{tm10(Pdgfra/tor)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003091	abnormal cell migration	"defect in the movement of cells during developmental processes" [smb:Susan M. Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Hoxa5^tm1Rob/Hoxa5^tm1Rob Genetic Background: involves: 129S/SvEv * C57BL/6 * MF1
MP:0003141	cardiac fibrosis	"formation of fibrous tissue within the heart often resulting from inflammation or injury " [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0003215	renal interstitial fibrosis	"formation of fibrous tissue within the interstices of the kidney as a result of repair or a reactive process" [RGD:Rat Genome Database submission]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0003229	abnormal vitelline vasculature	"malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003231	abnormal placental vasculature	"malformation in the vessels of the placenta" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93157]	Show Allelic Composition: Pdgfra^{tm11(EGFP)Sor}/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0003312	abnormal locomotor coordination	"reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm6Sor/Pdgfra^tm6Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm6Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003586	ureter dilation	"abnormal distention of the ureter due to accumulation of fluid" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0003587	ureter obstruction	"any impediment, blockage, or reversal of the normal flow of the urine towards the bladder" [ncbi:Matthew Mailman, NCBI request]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0003672	abnormal ureter development	"anomalous differentiation of the tube that conducts the urine from the renal pelvis to the bladder" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:96485]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0003717	pallor	"an unnatural paleness to the skin, generally attributable to anemia" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]	Show Allelic Composition: Pdgfra^{tm1.1(cre/Esr1)Nshk}/Pdgfra⁺,Runx1^tm1Medv/Runx1^tm1Medv Genetic Background:* involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj
MP:0003851	skeletal muscle interstitial fibrosis	"formation of fibrous tissue within the interstices of skeletal muscle as a result of repair or a reactive process" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL
MP:0003924	herniated diaphragm	"protrusion of abdominal contents into the thoracic cavity through the diaphragm" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Ndufs4^tm1.1Rpa/Ndufs4^tm1.1Rpa Genetic Background: involves: 129S4/SvJaeSor
MP:0003939	abnormal myotome morphology	"structural anomaly in the mesoderm that is derived from the somite that is fated to beome the musculature" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0003984	embryonic growth retardation	"slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0004160	retroesophageal right subclavian artery	"the subclavian artery aberrantly originates from the aortic arch distal to the origin of the left subclavian artery, i.e., it is the last branch of the aortic arch" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0004174	abnormal spine curvature	"deviation from the typical S-shape of the spine" [smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0004180	failure of initiation of embryo turning	"failure to begin the axial rotation of the germ layers of the embryo during the primitive streak/early somite stage (E8.5-E9.5)" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0004194	abnormal kidney pelvis morphology	"any structural anomaly of the funnel shaped proximal portion of the ureter that is formed by convergence of the major calices" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0004199	enlarged fetal size	"larger proportions of a fetus compared to littermates (sensu Mus: from E14 through birth)" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0004202	pulmonary hyperplasia	"overdevelopment or increased size, usually due an increased number of cells of the respiratory organ in all or part of the organ" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0004260	enlarged placenta	"increased size of the size or shape of the organ of metabolic interchange between fetus and mother" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0004345	abnormal acromion morphology	"any structural anomaly of the lateral end of the spine of the scapula which projects as a broad flattened process and articulates with the clavicle, and forms the point of the shoulder" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0004467	absent zygomatic bone	"absence of the quadrilateral bone that forms the prominence of the cheek" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0004471	short nasal bone	"reduced length of either of two rectangular bone plates forming the bridge of the nose" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor
MP:0004506	abnormal pubic bone morphology	"any structural anomaly in the forward portion of either of the hipbones, at the juncture forming the front arch of the pelvis" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0004508	abnormal shoulder bone morphology	"any structural anomaly of the bones of the shoulder by which the limbs attach to the axial skeleton " [MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0004546	esophagus hyperplasia	"overdevelopment or increased size, usually due an increased number of cells of the esophagus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0004625	abnormal rib attachment	"any anomaly in the in the normal joining of the ribs to the vertebral column or to the sternum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^{tm10(Pdgfra/tor)Sor}/Pdgfra^{tm10(Pdgfra/tor)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0004686	decreased length of long bones	"reduced end-to-end length of the several elongated bones of the extremities" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0004726	abnormal nasal capsule morphology	"any structural abnormality in the cartilage around the developing nasal cavity of the embryo" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0005031	abnormal trophoblast	"malformation of the mesectodermal cell layer covering the blastocyst that erodes the uterine mucosa and contributes to the formation of the placenta" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0005181	decreased circulating estradiol level	"less than the normal blood concentration of this most potent naturally occurring estrogen in mammals" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0005264	glomerulosclerosis	"hyaline deposits or scarring within the renal glomeruli, often occurring with renal arteriosclerosis or diabetes" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0005508	abnormal skeleton morphology	"malformation of the bony framework of the body in vertebrates" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]	Show Allelic Composition: Lepr^db/Lepr^db Genetic Background: BKS.Cg-Dock7^m +/+ Lepr^db/J Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Zfp950^{Gt(ROSA)76Sor}/Zfp950^{Gt(ROSA)76Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0005536	Leydig cell hypoplasia	"reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0005592	abnormal vascular smooth muscle morphology	"structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0006042	increased apoptosis	"greater than normal programmed cell death" [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0006050	pulmonary fibrosis	"formation of fibrous tissue within the lung often resulting from inflammation or injury " [RGD:Rat Genome Database submission, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0006113	abnormal heart septum morphology	"abnormality in the wall between the atria or ventricles of the heart, usually incomplete closure" [ncbi:Matthew Mailman, NCBI request, smb:Susan M Bello, Mouse Genome Informatics Curator]	Show Allelic Composition: Pdgfra^{tm10(Pdgfra/tor)Sor}/Pdgfra^{tm10(Pdgfra/tor)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0006301	abnormal mesenchyme morphology	"abnormality in the loosely packed, unspecialized cells that derive mostly from the mesoderm and contribute to connective tissue, bone, cartilage and circulatory and lymphatic systems." [J:120305, mnk:Michelle Knowlton_MGI Curator]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0006379	abnormal spermatocyte morphology	"anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0006418	abnormal testis cord formation	"any structural anomaly in the formation of the attachments derived from the primordial seminiferous cords that differentiate into seminiferous tubules in adolescence; defective testis cord formation is most likely to reflect abnormal function of either Sertoli cells or peritubular myoid (PTM) cells which normally cooperate to deposit a layer of basal lamina that defines the edges of individual testis cords" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0008011	intestinal polyps	"abnormal tissue masses that protrude into the lumen of the intestine and are tethered to the wall of the intestine" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0008288	abnormal adrenal cortex morphology	"any structural anomaly of the thick outer layer of the adrenal gland that produces and secretes steroid hormones such as corticosterone, estrone and aldosterone" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0008525	decreased skull height	"decrease in the distance between the cranial base and the upper domelike portion of the skull" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Mir140^tm1.1Tkob/Mir140^tm1.1Tkob,Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Col2a1-cre)1Rsjo/0 Genetic Background: involves: 129S4/SvJae * C57BL/6 * FVB/N * SJL
MP:0008856	fetal bleb	"presence of subepidermal blister-like structures on the skin, often on the head, formed during embryonic development and usually filled with blood" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm7Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0008869	anovulation	"complete failure of ovum to be released from an ovarian follicle" [MESH:C13.351.500.056.630.050, MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0009370	decreased thecal cell number	"fewer than normal numbers of cells in the sheath of stroma surrounding a secondary ovarian follicle" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0009657	failure of chorioallantoic fusion	"failure to initiate and/or complete the formation of a highly vascularized extra-embryonic fetal membrane by fusion of the chorion and allantois" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor,Pdgfrb^tm3Sor/Pdgfrb^tm3Sor Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0009888	palatal shelves fail to meet at midline	"polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0009890	cleft secondary palate	"congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0009901	abnormal frontonasal prominence morphology	"any structural anomaly of an unpaired facial process in the embryo formed from the tissues surrounding the forebrain vesicle that develops into the forehead and bridge of the nose/snout" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0009932	skin fibrosis	"invasion of fibrous connective tissue into the skin, often resulting from inflammation or injury" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL
MP:0010363	increased fibrosarcoma incidence	"greater than the expected number of a highly aggressive malignant neoplasm arising from fibrous connective tissue, in a specific population in a given time period" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]	Show Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL
MP:0010402	ventricular septal defect	"abnormal communications between the two lower chambers of the heart, including such defects in the perimembranous, inlet, outlet (infundibular), central muscular, marginal muscular, or apical muscular regions" [MESH:C14.240.400.560.540]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA Allelic Composition: Pdgfra^tm2Sor/Pdgfra^tm2Sor Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0010418	perimembraneous ventricular septal defect	"abnormal communications between the two lower chambers of the heart, occurring in the membranous septum with defects in the adjacent muscular portion of the septum; it is generally located in the LV outflow tract just below the aortic valve, associated with pouches or aneurysms of the septal leaflet of the tricuspid valve, which may partially or completely close the defect; an LV-to-RA shunt may also be associated with this defect" [http://emedicine.medscape.com]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/0 Genetic Background: Not Specified
MP:0010901	abnormal pulmonary alveolar parenchyma morphology	"any structural anomaly of the distinguishing cell types of the lung alveolar tissue, including pulmonary epithelial cells (pneumocytes), alveolar capillary endothelial cells, interstitial cells (fibroblasts) and alveolar macrophages" [ISBN:070202788 "Saunders Comprehensive Veterinary Dictionary, 3rd edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]	Show Allelic Composition: Hoxa5^tm1Rob/Hoxa5^tm1Rob,Pdgfra^{tm11(EGFP)Sor}/Pdgfra⁺ Genetic Background: involves: 129S/SvEv * 129S4/SvJaeSor * C57BL/6 * MF1
MP:0011085	complete postnatal lethality	"premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011086	partial postnatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms anytime between the neonatal period and weaning age (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011088	partial neonatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm5Sor/Pdgfra^tm5Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm5Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0011089	complete perinatal lethality	"death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0011090	partial perinatal lethality	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm11Sor/Pdgfrb^tm11Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0011091	complete prenatal lethality	"death of all organisms of a given genotype in a population between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Maff^tm1.1Jeng/Maff^tm1.1Jeng Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1
MP:0011098	complete embryonic lethality during organogenesis	"death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra^{tm11(EGFP)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^{tm1.1(cre/Esr1)Nshk}/Pdgfra⁺,Runx1^tm1Medv/Runx1^tm1Medv Genetic Background:* involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj
MP:0011108	partial embryonic lethality during organogenesis	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm2Sor/Pdgfra^tm2Sor Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0011109	partial lethality throughout fetal growth and development	"the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J) Allelic Composition: Pdgfra^{tm10(Pdgfra/tor)Sor}/Pdgfra^{tm10(Pdgfra/tor)Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0011129	decreased secondary ovarian follicle number	"fewer than normal numbers of the ovarian follicle in which the primary oocyte attains its full size and is surrounded by an extracellular glycoprotein layer (zona pellucida) that separates it from a peripheral layer of follicular cells permeated by one or more fluid-filled antra; the primary oocyte occupies the cumulus oophorus while the theca of the follicle develops into internal and external layers" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: Pdgfra^tm1Sor/Pdgfra⁺,Schip1^{Gt(ROSA)77Sor}/Schip1^{Gt(ROSA)77Sor} Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6) Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm1Sor/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0011147	increased mesenchymal cell proliferation involved in lung development	"increase in the expansion rate of a lung mesenchymal cell population by cell division" [MGI:anna]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011180	abnormal hematopoietic cell number	"any anomaly in the expected number of cells of the hematopoietic lineage" [CL:0000988, MGI:csmith]	Show Allelic Composition: Pdgfra^{tm1.1(cre/Esr1)Nshk}/Pdgfra⁺,Runx1^tm1Medv/Runx1^tm1Medv Genetic Background:* involves: 129P2/OlaHsd * C57BL/6NCrlj * CBA/JNCrlj
MP:0011185	absent primitive endoderm	"absence of the monolayer of cells derived from and located on the surface of inner cell mass, directly facing the blastocoele, and is separated from the more centrally located epiblast by basal lamina; the primitive endoderm give rises to the visceral endoderm and the parietal endoderm" [PMID:21123814]	Show Allelic Composition: G0s2^tm1Jgte/G0s2^tm1Jgte Genetic Background: involves: 129S7/SvEvBrd
MP:0011294	renal glomerulus hypertrophy	"increase in the bulk size of the capillary loops of the kidney that normally function as a filtration unit, due to cell enlargement" [MGI:anna]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0011377	renal glomerulus fibrosis	"formation of fibrous tissue in the renal glomerulus as a result of repair or a reactive process" [MGI:anna]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011385	abnormal testosterone level	"anomaly in the concentration of a potent androgen that promotes development of male secondary sex characteristics and the development of spermatozoa and may regulate sexual desire and help maintain bone and muscle health in both males and females" [ISBN:0-683-40008-8]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Tg(Nr5a1-cre)2Klp/0 Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0011426	abnormal ureter smooth muscle morphology	"any structural anomaly of the smooth muscle tissue surrounding the epithelium of the ureter" [MGI:anna]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011703	increased fibroblast proliferation	"greater the expansion rate of a fibroblast cell population by cell division" [MGI:csmith]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Pdgfra^tm13.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0011748	intestinal fibrosis	"formation of fibrous tissue in any part of the intestine as a result of repair or a reactive process" [MGI:csmith]	Show Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6 Allelic Composition: Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm13Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 Allelic Composition: Cdkn2a^tm1Rdp/Cdkn2a^tm1Rdp,Gt(ROSA)26Sor^{tm1(cre/ERT)Nat}/Gt(ROSA)26Sor⁺,Pdgfra^tm12Sor/Pdgfra⁺ Genetic Background: involves: 129 * 129/Sv * C57BL/6J * SJL
MP:0012082	delayed heart development	"late onset of the induction and/or differentiation of the heart" [MGI:anna]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0012251	abnormal diaphragm development	"malformation or incomplete differentiation of the thin musculomembranous barrier separating the abdominal and thoracic cavities and functioning in respiration" [MGI:anna]	Show Allelic Composition: Pdgfra^tm2Sor/Pdgfra^tm2Sor Genetic Background: involves: 129S4/SvJaeSor * C57BL/6
MP:0012279	wide sternum	"an increase in the width of the long flat bone of the chest that articulates with the clavicle and first seven rib pairs" [MGI:anna]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0012752	abnormal cardiac neural crest cell migration	"any anomaly in the migratory path of cardiac neural crest cells (NCCs), a subpopulation of cranial NCCs which originate from the lower hindbrain between the otic placode and third somite and migrate to the circumpharyngeal ridge (an arc-shape ridge located dorsal to the forming caudal pharyngeal arches) and then into the 3rd, 4th and 6th pharyngeal arches and the cardiac outflow tract (OFT); cardiac NCCs undergo migration away from the neural tube by following a dorsolateral path under the ectoderm, leading them to the pharyngeal arches; after pausing, they resume migration under the pharyngeal endoderm and, along the aortic arch arteries, populate the cardiac OFT where they contribute the aorticopulmonary septum, and ultimately colonize the heart to form the ventricular septum and cardiac ganglia" [MGI:anna]	Show Allelic Composition: Pdgfra^tm8Sor/Pdgfra^tm8Sor,Pdgfrb^tm1Mdt/Pdgfrb^tm1Mdt,H2afv^{Tg(Wnt1-cre)11Rth}/? Genetic Background: involves: C57BL/6 * CBA
MP:0012754	abnormal cranial neural crest cell morphology	"any structural anomaly of the neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage" [http://discovery.lifemapsc.com/in-vivo-development/neural-crest/cranial-neural-crest, http://embryology.med.unsw.edu.au/embryology/index.php?title=Neural_Crest_Development#Cranial_neural_crest, http://en.wikipedia.org/wiki/Cranial_neural_crest, MGI:anna]	Show Allelic Composition: Brca1^tm2Cxd/Brca1^tm2Cxd Genetic Background: involves: 129S6/SvEvTac * NIH Black Swiss Allelic Composition: Pdgfra^tm1Sor/Pdgfra^tm1Sor Genetic Background: either: 129S4/SvJaeSor-Pdgfra^tm1Sor or (involves: 129S4/SvJaeSor * C57BL/6J)
MP:0014166	ectopic cranial bone	"the appearance of an extra bone structure at an atypical location in or near the cranium" [MGI:csmith]	Show Allelic Composition: Pdgfra^{tm9(Pdgfra/Fgfr1)Sor}/Pdgfra⁺ Genetic Background: either: (involves: 129S4/SvJaeSor) or (involves: 129S4/SvJaeSor * C57BL/6)
MP:0020417	increased fibroblast chemotaxis	"increase in the directed movement response of a fibroblast cell population guided by a specific chemical concentration gradient; movement may be towards a higher concentration (positive chemotaxis) or towards a lower concentration (negative chemotaxis)" [mgi:anna, PMID:19217431]	Show Allelic Composition: Pdgfra^tm12.1Sor/Pdgfra⁺ Genetic Background: involves: 129 * C57BL/6
MP:0030189	broad snout	"increased width of the anterior facial part of the face or muzzle containing the oral and nasal regions" [MGI:anna]	Show Allelic Composition: Arid5b^{Gt(ROSA)75Sor}/Arid5b^{Gt(ROSA)75Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Tiparp^{Gt(ROSA)79Sor}/Tiparp^{Gt(ROSA)79Sor} Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: 2610005L07Rik^{Gt(ROSA)73Sor}/2610005L07Rik^{Gt(ROSA)73Sor},Pdgfra^tm2Sor/Pdgfra⁺ Genetic Background: involves: 129S4/SvJaeSor Allelic Composition: Pdgfra^tm2Sor/Pdgfra⁺,Plekha1^{Gt(ROSA)82Sor}/Plekha1^{Gt(ROSA)82Sor} Genetic Background: involves: 129S4/SvJaeSor

External programs and data are copyrighted by and are the property of their respective authors. The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation
		© Olivier Tassy / Olivier Pourquie 2007-2024 contact: otassy@igbmc.fr

ENSMUSG00000029231