ENSMUSG00000017776


Mus musculus

Features
Gene ID: ENSMUSG00000017776
  
Biological name :Crk
  
Synonyms : Adapter molecule crk / Crk / Q64010
  
Possible biological names infered from orthology : CRK proto-oncogene, adaptor protein / P46108
  
Species: Mus musculus
  
Chr. number: 11
Strand: 1
Band: B5
Gene start: 75679259
Gene end: 75706908
  
Corresponding Affymetrix probe sets: 10378732 (MoGene1.0st)   1416201_at (Mouse Genome 430 2.0 Array)   1425855_a_at (Mouse Genome 430 2.0 Array)   1436835_at (Mouse Genome 430 2.0 Array)   1448248_at (Mouse Genome 430 2.0 Array)   1460176_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000104063
Ensembl peptide - ENSMUSP00000017920
Ensembl peptide - ENSMUSP00000090803
Ensembl peptide - ENSMUSP00000104064
Ensembl peptide - ENSMUSP00000116527
NCBI entrez gene - 12928     See in Manteia.
MGI - MGI:88508
RefSeq - XM_006532125
RefSeq - NM_001277219
RefSeq - NM_001277221
RefSeq - NM_133656
RefSeq - XM_006532124
RefSeq Peptide - NP_001264150
RefSeq Peptide - NP_598417
RefSeq Peptide - NP_001264148
swissprot - Q5ND50
swissprot - Q5ND51
swissprot - Q64010
swissprot - Q8JZR2
swissprot - F7D232
swissprot - Q3TQV3
Ensembl - ENSMUSG00000017776
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 crkENSDARG00000055635Danio rerio
 CRKENSGALG00000002656Gallus gallus
 CRKENSG00000167193Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Crkl / P47941 / Crk-like protein / P46109* / CRK like proto-oncogene, adaptor protein*ENSMUSG0000000613458


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR001452  SH3 domain
 IPR035457  CRK, N-terminal SH3 domain
 IPR035458  CRK, C-terminal SH3 domain
 IPR036028  SH3-like domain superfamily
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001878 response to yeast IEA
 biological_processGO:0008360 regulation of cell shape IEA
 biological_processGO:0009966 regulation of signal transduction IEA
 biological_processGO:0009967 positive regulation of signal transduction IEA
 biological_processGO:0014911 positive regulation of smooth muscle cell migration IEA
 biological_processGO:0030307 positive regulation of cell growth ISO
 biological_processGO:0032956 regulation of actin cytoskeleton organization IEA
 biological_processGO:0035020 regulation of Rac protein signal transduction IEA
 biological_processGO:0035728 response to hepatocyte growth factor IEA
 biological_processGO:0042542 response to hydrogen peroxide IEA
 biological_processGO:0043087 regulation of GTPase activity IEA
 biological_processGO:0043393 regulation of protein binding IEA
 biological_processGO:0045953 negative regulation of natural killer cell mediated cytotoxicity IEA
 biological_processGO:0048013 ephrin receptor signaling pathway IEA
 biological_processGO:0061045 negative regulation of wound healing IEA
 biological_processGO:0061847 response to cholecystokinin IEA
 biological_processGO:0071538 SH2 domain-mediated complex assembly ISO
 biological_processGO:0071560 cellular response to transforming growth factor beta stimulus IEA
 biological_processGO:0071732 cellular response to nitric oxide IEA
 biological_processGO:1900026 positive regulation of substrate adhesion-dependent cell spreading IEA
 biological_processGO:1901652 response to peptide IEA
 biological_processGO:1990090 cellular response to nerve growth factor stimulus IEA
 biological_processGO:1990314 cellular response to insulin-like growth factor stimulus IEA
 biological_processGO:1990859 cellular response to endothelin IEA
 biological_processGO:2000146 negative regulation of cell motility IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0015629 actin cytoskeleton IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0045121 membrane raft IEA
 molecular_functionGO:0001784 phosphotyrosine residue binding IEA
 molecular_functionGO:0005070 SH3/SH2 adaptor activity IPI
 molecular_functionGO:0005159 insulin-like growth factor receptor binding IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0008092 cytoskeletal protein binding IEA
 molecular_functionGO:0017124 SH3 domain binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030674 protein binding, bridging IEA
 molecular_functionGO:0042169 SH2 domain binding IPI
 molecular_functionGO:0043621 protein self-association IEA
 molecular_functionGO:0045309 protein phosphorylated amino acid binding ISO
 molecular_functionGO:0046875 ephrin receptor binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:1990782 protein tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
ARMS-mediated activation
Downstream signal transduction
Regulation of actin dynamics for phagocytic cup formation
p130Cas linkage to MAPK signaling for integrins
VEGFA-VEGFR2 Pathway
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases
MET activates RAP1 and RAC1
MET receptor recycling
NTRK2 activates RAC1
Regulation of signaling by CBL


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0000788 abnormal cerebral cortex morphology "malformed gray cellular mantle covering the surface of the brain" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:38857]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000807 abnormal hippocampus morphology "absent or malformed deep lying structure of the cerebrum involved with memory storage and spatial navigation" [The Atlas of Mouse Development:ISBN 0-12-402035-6, MGI:Cls, J:38857]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000812 abnormal dentate gyrus morphology "absence or malformation of one of two interlocking gyri of the hippocampus that contains granule cells, which project to the pyramidal cells and interneurons of the CA3 region of the ammon gyrus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:38857]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000852 small cerebellum "reduced size of cerebellum" [MGI:CLS, J:17203, J:67524]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000854 abnormal cerebellum development "malformed or incomplete differentiation of the part of the metencephalon that lies dorsal to the pons and medulla behind the brain stem and controls balance for walking and standing, modulates the force and range of movement and is involved in the learning of motor skills " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000857 abnormal cerebellar foliation "malformation of small offshoots of the cerebellar lobules" [Principles of Neural Science:ISBN 0-8385-8034-3, J:52951]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0000890 thin cerebellar molecular layer "reduced width of the outer of the three cortical layers of the cerebellum" [J:46854]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Il17atm1Yiw/Il17atm1Yiw
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Il17atm1Yiw/Il17atm1Yiw
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0001914 hemorrhage "loss of blood from the vascular compartment to the exterior or into nonvascular body space as a result of rupture or severance of the blood vessels" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002082 postnatal lethality "premature death anytime after postnatal day 1 to weaning age (3 weeks)" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Chrnetm1Vwi/Chrnetm1Vwi
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002192 hydrops fetalis "an abnormal accumulation of serous fluid in fetal tissues" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002233 abnormal nose morphology "any structural anomaly of the organ that is specialized for smell and is part of the respiratory system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002238 abnormal nasal mucosa morphology "any structural anomaly of the mucous membrane that lines the nasal cavity" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002753 dilated left ventricle "an expansion in the volume of the lower left chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002754 dilated right ventricle "an expansion in the volume of the lower right chamber of the heart" [J:82859, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0002762 ectopic granule cells "granule cell body resides in a place other than the external or internal granule layer of the cerebellum" [J:4978]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0005294 abnormal heart ventricle morphology "structural anomaly of one or both of the two lower chambers of the heart " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0005590 increased vasodilation "greater than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0005592 abnormal vascular smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0008284 abnormal hippocampus pyramidal cell layer 
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0008439 abnormal cortical plate morphology "any strucutral anomaly of the outer neural tube region in which post-mitotic neuroblasts migrate along radial glia to form the adult cortical layers" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator", PMID:1812236]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0008572 abnormal Purkinje cell dendrite morphology "any strucutral anomaly of the Purkinje cell body projections with hundreds of parallel spiny branches reaching up into the molecular layer" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0009888 palatal shelves fail to meet at midline "polarized growth towards the midline following palatal shelf elevation does not occur" [PMID:16942766]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0009890 cleft secondary palate "congenital fissure of the tissues normally uniting to form the secondary palate" [PMID:16680722]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0009969 abnormal cerebral cortex pyramidal cell morphology "any structural anomaly of the projection neurons in the pyramidal cell layer of the cerebral cortex" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: Crktm1Cur/Crktm1Cur,Crkltm1Cur/Crkltm1Cur,Tg(Nes-cre)1Kln/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0011089 complete perinatal lethality "death of all organisms of a given genotype in a population within the perinatal period (Mus: E18.5 through postnatal day 1)" [MGI:csmith]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0011109 partial lethality throughout fetal growth and development "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between the completion of organogenesis and birth (Mus: E14 to approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

 MP:0012729 abnormal common carotid artery morphology "any structural anomaly of the left or right common carotid arteries which extend headward on each side of the anterior neck and deliver oxygenated nutrient filled blood from the heart to the head, neck and brain; the left originates in the arch of the aorta over the heart; the right originates in the brachiocephalic trunk, the largest branch from the arch of the aorta; each common carotid artery divides into an external and an internal carotid artery" [MGI:anna]
Show

Allelic Composition: Ntn1Gt(ST629)Byg/Ntn1Gt(ST629)Byg
Genetic Background: involves: 129P2/OlaHsd

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026786 Q8R5A3 / Apbb1ip / amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein / Q7Z5R6* / amyloid beta precursor protein binding family B member 1 interacting protein*  / complex / reaction
 ENSMUSG00000027646 Src / P05480 / Neuronal proto-onco tyrosine-protein kinase Src / P12931* / SRC proto-oncogene, non-receptor tyrosine kinase*  / complex / reaction
 ENSMUSG00000021457 Syk / P48025 / spleen tyrosine kinase / P43405* / spleen associated tyrosine kinase*  / reaction / complex
 ENSMUSG00000041112 Elmo1 / Q8BPU7 / Engulfment and cell motility protein 1 / Q92556* / engulfment and cell motility 1*  / reaction / complex
 ENSMUSG00000059089 Fcgr4 / A0A0B4J1G0 / Low affinity immunoglobulin gamma Fc region receptor IV / P08637* / FCGR3A* / FCGR3B* / O75015* / Fc fragment of IgG receptor IIIa* / Fc fragment of IgG receptor IIIb*  / reaction / complex
 ENSMUSG00000027859 Ngf / P01139 / Beta-nerve growth factor / P01138* / nerve growth factor*  / complex
 ENSMUSG00000023951 Vegfa / Q00731 / vascular endothelial growth factor A / P15692*  / complex / reaction
 ENSMUSG00000044147 Arf6 / P62331 / ADP-ribosylation factor 6 / P62330*  / complex
 ENSMUSG00000062960 Kdr / kinase insert domain receptor / P35968*  / complex / reaction
 ENSMUSG00000028072 Ntrk1 / Q3UFB7 / High affinity nerve growth factor receptor / P04629* / neurotrophic receptor tyrosine kinase 1*  / complex
 ENSMUSG00000002033 Cd3g / P11942 / T-cell surface glycoprotein CD3 gamma chain / P09693* / CD3g molecule*  / reaction / complex
 ENSMUSG00000044813 Shb / Q6PD21 / SH2 domain-containing adapter protein B / Q15464* / AL138752.2* / SH2 domain containing adaptor protein B*  / complex / reaction
 ENSMUSG00000024620 Pdgfrb / platelet-derived growth factor receptor beta isoform 2 / P09619* / platelet derived growth factor receptor beta*  / reaction / complex
 ENSMUSG00000015947 Fcgr1 / P26151 / High affinity immunoglobulin gamma Fc receptor I / Q92637* / FCGR1A* / FCGR1B* / P12314* / Fc fragment of IgG receptor Ib* / Fc fragment of IgG receptor Ia*  / complex / reaction
 ENSMUSG00000031955 Bcar1 / Q61140 / Breast cancer anti-estrogen resistance protein 1 / P56945* / BCAR1, Cas family scaffolding protein*  / reaction / complex
 ENSMUSG00000017670 Elmo2 / Q8BHL5 / Engulfment and cell motility protein 2 / Q96JJ3* / engulfment and cell motility 2*  / reaction / complex
 ENSMUSG00000031714 Gab1 / Q9QYY0 / GRB2-associated-binding protein 1 / Q13480*  / complex / reaction
 ENSMUSG00000005763 Cd247 / P24161 / T-cell surface glycoprotein CD3 zeta chain / P20963* / CD247 molecule*  / reaction / complex
 ENSMUSG00000000489 Pdgfb / platelet derived growth factor, B polypeptide / P01127* / platelet derived growth factor subunit B*  / complex / reaction
 ENSMUSG00000029231 P26618 / Pdgfra / Mus musculus platelet derived growth factor receptor, alpha polypeptide (Pdgfra), transcript variant 4, mRNA. / P16234* / platelet derived growth factor receptor alpha*  / complex / reaction
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / reaction
 ENSMUSG00000025856 Pdgfa / platelet derived growth factor subunit A / P04085*  / complex / reaction
 ENSMUSG00000059923 Grb2 / Q60631 / Growth factor receptor-bound protein 2 / P62993*  / reaction / complex
 ENSMUSG00000028864 Hgf / Q08048 / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain / P14210* / hepatocyte growth factor*  / complex / reaction
 ENSMUSG00000009376 Met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex / reaction
 ENSMUSG00000029528 Pxn / Q8VI36 / Paxillin / P49023*  / reaction / complex
 ENSMUSG00000068798 Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*  / reaction / complex
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / complex / reaction
 ENSMUSG00000058325 Dock1 / Q8BUR4 / Dedicator of cytokinesis protein 1 / Q14185* / dedicator of cytokinesis 1*  / complex / reaction
 ENSMUSG00000034342 Cbl / P22682 / E3 ubiquitin-protein ligase CBL / P22681* / Cbl proto-oncogene*  / complex / reaction
 ENSMUSG00000022607 Ptk2 / P34152 / PTK2 protein tyrosine kinase 2 / Q05397* / protein tyrosine kinase 2*  / complex / reaction
 ENSMUSG00000020689 Itgb3 / O54890 / Integrin beta-3 / P05106* / AC068234.1* / integrin subunit beta 3*  / complex / reaction
 ENSMUSG00000020740 Gga3 / Q8BMI3 / ADP-ribosylation factor-binding protein GGA3 / Q9NZ52* / golgi associated, gamma adaptin ear containing, ARF binding protein 3*  / complex
 ENSMUSG00000028465 Tln1 / P26039 / talin 1 / Q9Y490*  / reaction / complex
 ENSMUSG00000028001 Fga / E9PV24 / Fibrinogen alpha chain Fibrinopeptide A Fibrinogen alpha chain / P02671* / fibrinogen alpha chain*  / complex / reaction
 ENSMUSG00000052681 Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*  / reaction / complex
 ENSMUSG00000026193 Fn1 / P11276 / Fibronectin Anastellin / P02751* / fibronectin 1*  / reaction / complex
 ENSMUSG00000033860 Fgg / Q8VCM7 / Fibrinogen gamma chain / P02679*  / reaction / complex
 ENSMUSG00000033831 Fgb / Q8K0E8 / Fibrinogen beta chain Fibrinopeptide B Fibrinogen beta chain / P02675* / fibrinogen beta chain*  / complex / reaction
 ENSMUSG00000001930 Vwf / Von Willebrand factor / P04275*  / reaction / complex
 ENSMUSG00000034664 Itga2b / Q9QUM0 / integrin alpha 2b / P08514* / integrin subunit alpha 2b*  / complex / reaction






 

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