MP:0000694 | spleen hypoplasia | "small size due to reduced cell number in the spleen" [J:43971] |
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Allelic Composition: Tfap2etm1(cre)Will/Tfap2etm1(cre)Will Genetic Background: involves: 129S1/Sv * Black Swiss
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MP:0000715 | decreased thymocyte number | "fewer than expected number of precursors to T cells; these cells are lymphoid cells found in the thymus " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Cd3gtm1Amk/Cd3gtm1Amk,Tg(Igh-Pim1)1Brn/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6LiA * CBA
Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage Genetic Background: B6.129P2-Cd3gtm1.1Cage
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MP:0001823 | thymus hypoplasia | "small size due to reduced cell number in the thymus" [J:23255] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0001828 | abnormal T cell activation | "anomaly in the process of producing effector T cells from naive T cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0002145 | abnormal T lymphocyte development | "atypical production of or inability to produce mature T cells, and/or accumulation of T cell precursors" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0002444 | abnormal T cell physiology | "anomalous response of T lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage,Tg(TcrLCMV)318Sdz/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
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MP:0004392 | abnormal CD8-positive T cell physiology | "abnormal function of the subset of T lymphocytes that express the CD8 marker on the cell surface" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0005025 | response to infection | "the body s reaction to invasion and multiplication of microorganisms in its tissues, or the body s reaction to components of or toxins produced by pathogenic mircroorganisms " [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage Genetic Background: B6.129P2-Cd3gtm1.1Cage
Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage,Tg(TcrLCMV)318Sdz/0 Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * DBA/2 * FVB/N
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MP:0005079 | defective cytotoxic T cell cytolysis | "impaired ability of these cells to destroy or dissolve targeted cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:6692] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0005094 | abnormal T cell proliferation | "anomaly in the clonal expansion of naive T cells" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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MP:0006413 | increased T cell apoptosis | "increase in the number of T cells undergoing programmed cell death" [MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage Genetic Background: B6.129P2-Cd3gtm1.1Cage
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MP:0008079 | decreased CD8-positive T cell number | "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Cd3gtm1.1Cage/Cd3gtm1.1Cage Genetic Background: B6.129P2-Cd3gtm1.1Cage
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MP:0008101 | lymph node hypoplasia | "underdevelopment or reduced size, usually due to a reduced cell number, in the lymph nodes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Ctnnb1tm1Mmt/Ctnnb1+,Tg(Pou3f4-cre)32Cren/? Genetic Background: involves: 129X1/SvJ
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