ENSMUSG00000021270


Mus musculus

Features
Gene ID: ENSMUSG00000021270
  
Biological name :Hsp90aa1
  
Synonyms : Heat shock protein HSP 90-alpha / Hsp90aa1 / P07901
  
Possible biological names infered from orthology : heat shock protein 90 alpha family class A member 1 / P07900
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: F1
Gene start: 110690605
Gene end: 110702728
  
Corresponding Affymetrix probe sets: 10378848 (MoGene1.0st)   10402615 (MoGene1.0st)   10490946 (MoGene1.0st)   1426645_at (Mouse Genome 430 2.0 Array)   1433251_at (Mouse Genome 430 2.0 Array)   1437497_a_at (Mouse Genome 430 2.0 Array)   1438902_a_at (Mouse Genome 430 2.0 Array)   1441827_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000091921
Ensembl peptide - ENSMUSP00000121138
Ensembl peptide - ENSMUSP00000118189
Ensembl peptide - ENSMUSP00000114201
Ensembl peptide - ENSMUSP00000021698
NCBI entrez gene - 15519     See in Manteia.
MGI - MGI:96250
RefSeq - NM_010480
RefSeq Peptide - NP_034610
swissprot - P07901
swissprot - B7ZC50
swissprot - Q80Y52
swissprot - B7ZC49
swissprot - A2A6A2
Ensembl - ENSMUSG00000021270
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q90474ENSDARG00000010478Danio rerio
 HSP90AA1ENSGALG00000033212Gallus gallus
 P07900ENSG00000080824Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*ENSMUSG0000002394486
P08113 / Hsp90b1 / heat shock protein 90, beta (Grp94), member 1 / P14625* / heat shock protein 90 beta family member 1*ENSMUSG0000002004845
Trap1 / Q9CQN1 / Heat shock protein 75 kDa, mitochondrial / Q12931* / TNF receptor associated protein 1*ENSMUSG0000000598128


Protein motifs (from Interpro)
Interpro ID Name
 IPR001404  Heat shock protein Hsp90 family
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR019805  Heat shock protein Hsp90, conserved site
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR020575  Heat shock protein Hsp90, N-terminal
 IPR036890  Histidine kinase/HSP90-like ATPase superfamily
 IPR037196  HSP90, C-terminal domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006809 nitric oxide biosynthetic process TAS
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0006986 response to unfolded protein TAS
 biological_processGO:0007004 telomere maintenance via telomerase ISO
 biological_processGO:0009408 response to heat ISS
 biological_processGO:0009409 response to cold ISS
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation IEA
 biological_processGO:0021955 central nervous system neuron axonogenesis IMP
 biological_processGO:0030010 establishment of cell polarity IEP
 biological_processGO:0031396 regulation of protein ubiquitination ISO
 biological_processGO:0032273 positive regulation of protein polymerization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IMP
 biological_processGO:0042026 protein refolding TAS
 biological_processGO:0045040 protein import into mitochondrial outer membrane ISO
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process ISS
 biological_processGO:0045585 positive regulation of cytotoxic T cell differentiation TAS
 biological_processGO:0046677 response to antibiotic ISS
 biological_processGO:0048675 axon extension IMP
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0050821 protein stabilization ISO
 biological_processGO:0051131 chaperone-mediated protein complex assembly ISO
 biological_processGO:0051897 positive regulation of protein kinase B signaling IMP
 biological_processGO:0051973 positive regulation of telomerase activity ISO
 biological_processGO:1902949 positive regulation of tau-protein kinase activity IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 biological_processGO:1905323 telomerase holoenzyme complex assembly ISO
 cellular_componentGO:0005622 intracellular IDA
 cellular_componentGO:0005634 nucleus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0032587 ruffle membrane IDA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0042470 melanosome IEA
 cellular_componentGO:0043025 neuronal cell body IDA
 cellular_componentGO:0043209 myelin sheath IDA
 cellular_componentGO:0044294 dendritic growth cone IDA
 cellular_componentGO:0044295 axonal growth cone IDA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity ISO
 molecular_functionGO:0030235 nitric-oxide synthase regulator activity ISS
 molecular_functionGO:0030911 TPR domain binding ISS
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity IDA
 molecular_functionGO:0042826 histone deacetylase binding ISO
 molecular_functionGO:0048156 tau protein binding IEA
 molecular_functionGO:0051020 GTPase binding ISO
 molecular_functionGO:0051082 unfolded protein binding IEA
 molecular_functionGO:0070182 DNA polymerase binding ISO
 molecular_functionGO:0097110 scaffold protein binding ISO
 molecular_functionGO:0097718 disordered domain specific binding ISO
 molecular_functionGO:1990782 protein tyrosine kinase binding ISO


Pathways (from Reactome)
Pathway description
Signaling by ERBB2
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Regulation of actin dynamics for phagocytic cup formation
eNOS activation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
HSF1 activation
Attenuation phase
HSF1-dependent transactivation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
EPHB-mediated forward signaling
Sema3A PAK dependent Axon repulsion
VEGFA-VEGFR2 Pathway
VEGFR2 mediated vascular permeability
Anchoring of the basal body to the plasma membrane
Neutrophil degranulation
The role of GTSE1 in G2/M progression after G2 checkpoint
AURKA Activation by TPX2
Downregulation of ERBB2 signaling
ESR-mediated signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000443 abnormal snout morphology "anomalous structure or development of the anterior facial part of the muzzle" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Myo10tm2(KOMP)Wtsi/Myo10tm2(KOMP)Wtsi
Genetic Background: C57BL/6N-Myo10tm2(KOMP)Wtsi/Wtsi

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Hsp90aa1Tg(Tyr)2396BOve/Hsp90aa1Tg(Tyr)2396BOve
Genetic Background: FVB/N-Hsp90aa1Tg(Tyr)2396BOve

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
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Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0001539 decreased number of caudal vertebrae "reduced number of the bony segments of the tail" [Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Hsp90aa1Gt(S17-2G1)Sor/Hsp90aa1Gt(S17-2G1)Sor
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Hsp90aa1Tg(Tyr)2396BOve/Hsp90aa1Tg(Tyr)2396BOve
Genetic Background: FVB/N-Hsp90aa1Tg(Tyr)2396BOve

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0002376 abnormal dendritic cell physiology "failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:85808]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0002455 abnormal dendritic cell antigen presentation "impairment of these specialized cells to process and present antigen to T lymphoytes" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0003609 small scrotum "reduced size of the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, ncbi:Matthew Mailman, NCBI request]
Show

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0005169 abnormal male meiosis "malfunction in the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: B9d2/Tgfb1tm1Flv/Tgfb1tm2Flv,Foxp3tm4(YFP/icre)Ayr/Foxp3+
Genetic Background: involves: 129S1/Sv * 129S6/SvEvTac * 129X1/SvJ

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

Allelic Composition: Hsp90aa1tm1.2Udon/Hsp90aa1tm1.2Udon,Gt(ROSA)26Sortm9(cre/ESR1)Arte/Gt(ROSA)26Sor+
Genetic Background: involves: C57BL/6 * C57BL/6NTac * FVB/N

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Lin28atm1Gqda/Lin28atm1Gqda,Myf5tm3(cre)Sor/Myf5+
Genetic Background: involves: 129S4/SvJae * C57BL/6 * CD-1

 MP:0010052 increased grip strength "greater ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
Show

Allelic Composition: Hsp90aa1tm1(KOMP)Wtsi/Hsp90aa1tm1(KOMP)Wtsi
Genetic Background: C57BL/6N-Hsp90aa1tm1(KOMP)Wtsi/Wtsi

 MP:0011110 partial preweaning lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Hsp90aa1tm1.1Udon/Hsp90aa1tm1.1Udon
Genetic Background: involves: C57BL/6 * FVB

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / complex / reaction
 ENSMUSG00000007815 Rhoa / Q9QUI0 / ras homolog family member A / P61586*  / reaction
 ENSMUSG00000015656 Hspa8 / P63017 / Heat shock cognate 71 kDa protein / P11142* / heat shock protein family A (Hsp70) member 8*  / complex / reaction
 ENSMUSG00000029674 Limk1 / P53668 / LIM domain kinase 1 / P53667*  / complex / reaction
 ENSMUSG00000020580 Rock2 / Rho associated coiled-coil containing protein kinase 2 / O75116*  / reaction
 ENSMUSG00000017776 Crk / Q64010 / Adapter molecule crk / P46108* / CRK proto-oncogene, adaptor protein*  / reaction / complex
 ENSMUSG00000020689 Itgb3 / O54890 / Integrin beta-3 / P05106* / AC068234.1* / integrin subunit beta 3*  / reaction
 ENSMUSG00000023944 P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*  / complex
 ENSMUSG00000001729 Akt1 / P31750 / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA. / P31749* / AKT serine/threonine kinase 1*  / complex / reaction
 ENSMUSG00000029377 Ereg / Q61521 / Proepiregulin Epiregulin / O14944* / epiregulin*  / reaction
 ENSMUSG00000023951 Vegfa / Q00731 / vascular endothelial growth factor A / P15692*  / complex / reaction
 ENSMUSG00000021709 Erbin / Q80TH2 / Q96RT1* / erbb2 interacting protein*  / complex / reaction
 ENSMUSG00000031955 Bcar1 / Q61140 / Breast cancer anti-estrogen resistance protein 1 / P56945* / BCAR1, Cas family scaffolding protein*  / complex
 ENSMUSG00000017670 Elmo2 / Q8BHL5 / Engulfment and cell motility protein 2 / Q96JJ3* / engulfment and cell motility 2*  / complex / reaction
 ENSMUSG00000020122 Egfr / Q01279 / Epidermal growth factor receptor / P00533*  / reaction
 ENSMUSG00000019471 Cdc37 / Q61081 / Hsp90 co-chaperone Cdc37 Hsp90 co-chaperone Cdc37, N-terminally processed / Q16543* / cell division cycle 37*  / complex / reaction
 ENSMUSG00000031701 Dnaja2 / Q9QYJ0 / DnaJ homolog subfamily A member 2 / O60884* / DnaJ heat shock protein family (Hsp40) member A2*  / reaction
 ENSMUSG00000032285 Dnaja4 / Q9JMC3 / Mus musculus DnaJ heat shock protein family (Hsp40) member A4 (Dnaja4), transcript variant 1, mRNA. / Q8WW22* / DnaJ heat shock protein family (Hsp40) member A4*  / reaction
 ENSMUSG00000007655 Cav1 / P49817 / Caveolin-1 / Q03135*  / complex / reaction
 ENSMUSG00000029528 Pxn / Q8VI36 / Paxillin / P49023*  / complex / reaction
 ENSMUSG00000090877 P17879 / Hspa1b / Heat shock 70 kDa protein 1B / HSPA1A* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / reaction / complex
 ENSMUSG00000019768 Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*  / complex
 ENSMUSG00000046532 Ar / P19091 / Androgen receptor / P10275*  / complex
 ENSMUSG00000018166 Erbb3 / Q61526 / Receptor tyrosine-protein kinase erbB-3 / P21860* / erb-b2 receptor tyrosine kinase 3*  / reaction
 ENSMUSG00000082361 Btc / Q05928 / Probetacellulin Betacellulin / P35070* / betacellulin*  / reaction
 ENSMUSG00000022556 Hsf1 / P38532 / heat shock factor 1 / Q00613* / heat shock transcription factor 1*  / complex / reaction
 ENSMUSG00000091971 Q61696 / Hspa1a / Heat shock 70 kDa protein 1A / HSPA1B* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / complex / reaction
 ENSMUSG00000030357 Fkbp4 / P30416 / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed / Q02790* / FK506 binding protein 4*  / complex / reaction
 ENSMUSG00000024966 Stip1 / Q60864 / Stress-induced-phosphoprotein 1 / P31948*  / reaction / complex
 ENSMUSG00000044813 Shb / Q6PD21 / SH2 domain-containing adapter protein B / Q15464* / AL138752.2* / SH2 domain containing adaptor protein B*  / complex / reaction
 ENSMUSG00000062960 Kdr / kinase insert domain receptor / P35968*  / complex / reaction
 ENSMUSG00000041112 Elmo1 / Q8BPU7 / Engulfment and cell motility protein 1 / Q92556* / engulfment and cell motility 1*  / complex / reaction
 ENSMUSG00000033739 Fkbpl / O35450 / FK506-binding protein-like / Q9UIM3*  / reaction / complex
 ENSMUSG00000028978 Nos3 / P70313 / Nitric oxide synthase, endothelial / P29474* / nitric oxide synthase 3*  / reaction / complex
 ENSMUSG00000027646 Src / P05480 / Neuronal proto-onco tyrosine-protein kinase Src / P12931* / SRC proto-oncogene, non-receptor tyrosine kinase*  / complex / reaction
 ENSMUSG00000022385 Gtse1 / Q8R080 / G2 and S phase-expressed protein 1 / Q9NYZ3* / G2 and S-phase expressed 1*  / complex / reaction
 ENSMUSG00000032311 Nrg4 / Q9WTX4 / Pro-neuregulin-4, membrane-bound isoform Neuregulin-4 / Q8WWG1* / neuregulin 4*  / reaction
 ENSMUSG00000024486 Hbegf / Q06186 / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like growth factor / Q99075* / heparin binding EGF like growth factor*  / reaction
 ENSMUSG00000071072 Ptges3 / Q9R0Q7 / Prostaglandin E synthase 3 / Q15185*  / reaction / complex
 ENSMUSG00000062209 Erbb4 / Q61527 / Receptor tyrosine-protein kinase erbB-4 ERBB4 intracellular domain / Q15303* / erb-b2 receptor tyrosine kinase 4*  / reaction
 ENSMUSG00000022607 Ptk2 / P34152 / PTK2 protein tyrosine kinase 2 / Q05397* / protein tyrosine kinase 2*  / complex / reaction
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / reaction / complex
 ENSMUSG00000058325 Dock1 / Q8BUR4 / Dedicator of cytokinesis protein 1 / Q14185* / dedicator of cytokinesis 1*  / reaction / complex
 ENSMUSG00000028017 Egf / P01132 / Mus musculus epidermal growth factor (Egf), transcript variant 3, mRNA. / P01133* / epidermal growth factor*  / reaction
 ENSMUSG00000023067 Cdkn1a / P39689 / Cyclin-dependent kinase inhibitor 1 / P38936* / cyclin dependent kinase inhibitor 1A*  / reaction / complex
 ENSMUSG00000031870 Pgr / Q00175 / Progesterone receptor / P06401*  / complex
 ENSMUSG00000028410 Dnaja1 / P63037 / DnaJ homolog subfamily A member 1 / P31689* / DnaJ heat shock protein family (Hsp40) member A1*  / reaction
 ENSMUSG00000060275 Nrg2 / neuregulin 2 / O14511*  / reaction
 ENSMUSG00000040013 Fkbp6 / Q91XW8 / Inactive peptidyl-prolyl cis-trans isomerase FKBP6 / O75344* / FK506 binding protein 6*  / complex
 ENSMUSG00000059456 Ptk2b / Q9QVP9 / PTK2 protein tyrosine kinase 2 beta / Q14289* / protein tyrosine kinase 2 beta*  / reaction
 ENSMUSG00000027087 Itgav / P43406 / Integrin alpha-V Integrin alpha-V heavy chain Integrin alpha-V light chain / P06756* / integrin subunit alpha V*  / reaction
 ENSMUSG00000027804 Ppid / Q9CR16 / peptidylprolyl isomerase D (cyclophilin D) / Q08752* / peptidylprolyl isomerase D*  / complex
 ENSMUSG00000024290 Rock1 / P70335 / Rho-associated protein kinase 1 / Q13464* / Rho associated coiled-coil containing protein kinase 1*  / reaction
 ENSMUSG00000062312 Erbb2 / P70424 / Receptor tyrosine-protein kinase erbB-2 / P04626* / erb-b2 receptor tyrosine kinase 2*  / complex / reaction
 ENSMUSG00000021055 Esr2 / O08537 / Estrogen receptor beta / Q92731* / estrogen receptor 2*  / complex
 ENSMUSG00000024222 Fkbp5 / Q64378 / Peptidyl-prolyl cis-trans isomerase FKBP5 / Q13451* / FK506 binding protein 5*  / complex / reaction






 

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