ENSMUSG00000001175


Mus musculus

Features
Gene ID: ENSMUSG00000001175
  
Biological name :Calm1
  
Synonyms : Calm1 / Calmodulin-1 / P0DP26 / P0DP27 / P0DP28
  
Possible biological names infered from orthology : P0DP23
  
Species: Mus musculus
  
Chr. number: 12
Strand: 1
Band: E
Gene start: 100199435
Gene end: 100209814
  
Corresponding Affymetrix probe sets: 10397752 (MoGene1.0st)   1417365_a_at (Mouse Genome 430 2.0 Array)   1417366_s_at (Mouse Genome 430 2.0 Array)   1433592_at (Mouse Genome 430 2.0 Array)   1438825_at (Mouse Genome 430 2.0 Array)   1438826_x_at (Mouse Genome 430 2.0 Array)   1454611_a_at (Mouse Genome 430 2.0 Array)   1455571_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000001204
Ensembl peptide - ENSMUSP00000105709
NCBI entrez gene - 12313     See in Manteia.
MGI - MGI:88251
RefSeq - NM_001313934
RefSeq - NM_009790
RefSeq Peptide - NP_001300863
RefSeq Peptide - NP_033920
swissprot - P0DP26
swissprot - P0DP27
swissprot - P0DP28
swissprot - Q3UKW2
Ensembl - ENSMUSG00000001175
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 calm1bENSDARG00000034187Danio rerio
 CALM2ENSGALG00000010023Gallus gallus
 CALM1ENSG00000198668Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Calm2 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM3* / P0DP25* / calmodulin 3*ENSMUSG0000003643875
Calm3 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM1* / P0DP23*ENSMUSG0000001937075
Calml3 / Q9D6P8 / Calmodulin-like protein 3 / P27482* / calmodulin like 3*ENSMUSG0000006313065
Tnnc1 / P19123 / Troponin C, slow skeletal and cardiac muscles / P63316* / troponin C1, slow skeletal and cardiac type*ENSMUSG0000009189839
Tnnc2 / P20801 / Troponin C, skeletal muscle / P02585* / troponin C2, fast skeletal type*ENSMUSG0000001730039
Cabp4 / Q8VHC5 / Calcium-binding protein 4 / P57796*ENSMUSG0000002484234
Calm4 / Q9JM83 / Calmodulin-4 / Q9NZT1* / CALML5* / calmodulin like 5*ENSMUSG0000003376534
Cabp2 / calcium binding protein 2 / Q9NPB3*ENSMUSG0000002485734
Calml4 / Q91WQ9 / Calmodulin-like protein 4 / Q96GE6* / calmodulin like 4*ENSMUSG0000003224633
Cabp1 / Q9JLK7 / Calcium-binding protein 1 / Q9NZU7*ENSMUSG0000002954432
Cabp5 / Q9JLK3 / Calcium-binding protein 5 / Q9NP86*ENSMUSG0000000564932
Calm5 / calmodulin 5 / CALML5* / Q9NZT1* / calmodulin like 5*ENSMUSG0000009926925


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000086 G2/M transition of mitotic cell cycle IDA
 biological_processGO:0043388 positive regulation of DNA binding IDA
 biological_processGO:0060314 regulation of ryanodine-sensitive calcium-release channel activity ISS
 biological_processGO:0060315 negative regulation of ryanodine-sensitive calcium-release channel activity ISS
 cellular_componentGO:0000922 spindle pole IEA
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005819 spindle IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005856 cytoskeleton IEA
 cellular_componentGO:0008076 voltage-gated potassium channel complex IGI
 cellular_componentGO:0043209 myelin sheath IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0019855 calcium channel inhibitor activity ISS
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000021069 Pygl / Q9ET01 / Glycogen phosphorylase, liver form / P06737* / glycogen phosphorylase L*  / reaction
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / complex / reaction
 ENSMUSG00000022836 Mylk / myosin light chain kinase / Q15746*  / complex / reaction
 ENSMUSG00000028161 P63328 / Ppp3ca / protein phosphatase 3, catalytic subunit, alpha isoform / Q08209* / protein phosphatase 3 catalytic subunit alpha*  / complex / reaction
 ENSMUSG00000008859 Rala / P63321 / Ras-related protein Ral-A / P11233* / RAS like proto-oncogene A*  / complex / reaction
 ENSMUSG00000038128 Camk4 / calcium/calmodulin-dependent protein kinase IV / Q16566*  / complex
 ENSMUSG00000053819 Camk2d / Q6PHZ2 / Mus musculus calcium/calmodulin-dependent protein kinase II, delta (Camk2d), transcript variant 8, mRNA. / Q13557* / calcium/calmodulin dependent protein kinase II delta*  / complex / reaction
 ENSMUSG00000027544 Nfatc2 / Q60591 / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 / Q13469* / nuclear factor of activated T cells 2*  / reaction / complex
 ENSMUSG00000057897 Camk2b / P28652 / Calcium/calmodulin-dependent protein kinase type II subunit beta / Q13554* / calcium/calmodulin dependent protein kinase II beta*  / reaction / complex
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / reaction / complex
 ENSMUSG00000007655 Cav1 / P49817 / Caveolin-1 / Q03135*  / complex / reaction
 ENSMUSG00000025499 Hras / Q61411 / GTPase HRas GTPase HRas, N-terminally processed / P01112* / HRas proto-oncogene, GTPase*  / reaction
 ENSMUSG00000001729 Akt1 / P31750 / Mus musculus thymoma viral proto-onco 1 (Akt1), transcript variant 3, mRNA. / P31749* / AKT serine/threonine kinase 1*  / reaction / complex
 ENSMUSG00000062825 Actg1 / P63260 / Actin, cytoplasmic 2 Actin, cytoplasmic 2, N-terminally processed / P63261* / actin gamma 1*  / complex / reaction
 ENSMUSG00000032356 P27671 / Rasgrf1 / RAS protein-specific guanine nucleotide-releasing factor 1 / Q13972*  / complex / reaction
 ENSMUSG00000033953 Ppp3r1 / Q63810 / protein phosphatase 3, regulatory subunit B, alpha isoform (calcineurin B, type I) / P63098* / protein phosphatase 3 regulatory subunit B, alpha*  / complex / reaction
 ENSMUSG00000025958 Creb1 / Q01147 / Cyclic AMP-responsive element-binding protein 1 / P16220* / cAMP responsive element binding protein 1*  / reaction
 ENSMUSG00000032648 Pygm / Q9WUB3 / Glycogen phosphorylase, muscle form / P11217* / glycogen phosphorylase, muscle associated*  / reaction
 ENSMUSG00000024617 Camk2a / P11798 / Calcium/calmodulin-dependent protein kinase type II subunit alpha / Q9UQM7* / calcium/calmodulin dependent protein kinase II alpha*  / reaction / complex
 ENSMUSG00000031902 Nfatc3 / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3 / Q12968* / nuclear factor of activated T cells 3*  / complex / reaction
 ENSMUSG00000033016 Nfatc1 / nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1 / O95644* / nuclear factor of activated T cells 1*  / reaction / complex
 ENSMUSG00000021816 P48453 / Ppp3cb / protein phosphatase 3, catalytic subunit, beta isoform / P16298* / protein phosphatase 3 catalytic subunit beta*  / complex / reaction
 ENSMUSG00000028978 Nos3 / P70313 / Nitric oxide synthase, endothelial / P29474* / nitric oxide synthase 3*  / complex / reaction
 ENSMUSG00000029580 Actb / P60710 / Actin, cytoplasmic 1 Actin, cytoplasmic 1, N-terminally processed / POTEJ* / P60709* / P0CG39* / actin beta* / POTE ankyrin domain family member J*  / complex / reaction
 ENSMUSG00000021820 Camk2g / Q923T9 / Calcium/calmodulin-dependent protein kinase type II subunit gamma / Q13555* / calcium/calmodulin dependent protein kinase II gamma*  / complex / reaction
 ENSMUSG00000020734 Grin2c / Q01098 / Glutamate receptor ionotropic, NMDA 2C / Q14957* / glutamate ionotropic receptor NMDA type subunit 2C*  / reaction / complex
 ENSMUSG00000003752 Itpkc / Q7TS72 / Inositol-trisphosphate 3-kinase C / Q96DU7*  / complex
 ENSMUSG00000002771 Grin2d / Q03391 / Glutamate receptor ionotropic, NMDA 2D / O15399* / glutamate ionotropic receptor NMDA type subunit 2D*  / reaction / complex
 ENSMUSG00000020886 Dlg4 / Q62108 / Disks large homolog 4 / P78352* / discs large MAGUK scaffold protein 4*  / reaction / complex
 ENSMUSG00000025537 Phkg1 / P07934 / Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform / Q16816* / phosphorylase kinase catalytic subunit gamma 1*  / complex
 ENSMUSG00000024858 Grk2 / Q99MK8 / G protein-coupled receptor kinase 2 / P25098*  / reaction / complex
 ENSMUSG00000022055 Nefl / P08551 / Neurofilament light polypeptide / P07196* / neurofilament light*  / complex / reaction
 ENSMUSG00000030815 Phkg2 / Q9DB30 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / P15735* / phosphorylase kinase catalytic subunit gamma 2*  / complex
 ENSMUSG00000059003 Grin2a / P35436 / Glutamate receptor ionotropic, NMDA 2A / Q12879* / glutamate ionotropic receptor NMDA type subunit 2A*  / complex / reaction
 ENSMUSG00000027296 Itpka / Q8R071 / Inositol-trisphosphate 3-kinase A / P23677*  / complex
 ENSMUSG00000034055 Phka1 / P18826 / Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform / P46020* / phosphorylase kinase regulatory subunit alpha 1*  / complex
 ENSMUSG00000026959 Grin1 / P35438 / Glutamate receptor ionotropic, NMDA 1 / Q05586* / glutamate ionotropic receptor NMDA type subunit 1*  / complex / reaction
 ENSMUSG00000031295 Phka2 / Q8BWJ3 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / P46019* / phosphorylase kinase regulatory subunit alpha 2*  / complex
 ENSMUSG00000017774 Myo1c / Q9WTI7 / Unconventional myosin-Ic / O00159* / myosin IC*  / complex
 ENSMUSG00000036879 Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*  / complex
 ENSMUSG00000028068 Iqgap3 / IQ motif containing GTPase activating protein 3 / Q86VI3*  / complex / reaction
 ENSMUSG00000052374 Actn2 / Q9JI91 / Alpha-actinin-2 / P35609* / actinin alpha 2*  / reaction / complex
 ENSMUSG00000021676 Iqgap2 / Q3UQ44 / Ras GTPase-activating-like protein IQGAP2 / Q13576* / IQ motif containing GTPase activating protein 2*  / complex / reaction
 ENSMUSG00000038855 Itpkb / inositol-trisphosphate 3-kinase B / P27987*  / complex
 ENSMUSG00000030209 Grin2b / glutamate receptor, ionotropic, NMDA2B (epsilon 2) / Q13224* / glutamate ionotropic receptor NMDA type subunit 2B*  / reaction / complex
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / reaction / complex
 ENSMUSG00000067220 Cnga1 / P29974 / cGMP-gated cation channel alpha-1 / P29973* / cyclic nucleotide gated channel alpha 1*  / reaction / complex
 ENSMUSG00000071037 Camkmt / Q3U2J5 / Calmodulin-lysine N-methyltransferase / Q7Z624*  / reaction
 ENSMUSG00000030536 Iqgap1 / Q9JKF1 / Ras GTPase-activating-like protein IQGAP1 / P46940* / IQ motif containing GTPase activating protein 1*  / complex / reaction






 

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