ENSMUSG00000036879


Mus musculus

Features
Gene ID: ENSMUSG00000036879
  
Biological name :Phkb
  
Synonyms : Phkb / Phosphorylase b kinase regulatory subunit beta / Q7TSH2
  
Possible biological names infered from orthology : phosphorylase kinase regulatory subunit beta / Q93100
  
Species: Mus musculus
  
Chr. number: 8
Strand: 1
Band: C3
Gene start: 85840959
Gene end: 86061376
  
Corresponding Affymetrix probe sets: 10573637 (MoGene1.0st)   1434511_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000125197
Ensembl peptide - ENSMUSP00000124522
Ensembl peptide - ENSMUSP00000125690
Ensembl peptide - ENSMUSP00000124939
Ensembl peptide - ENSMUSP00000125051
Ensembl peptide - ENSMUSP00000050788
NCBI entrez gene - 102093     See in Manteia.
MGI - MGI:97578
RefSeq - XM_017312500
RefSeq - XM_006530530
RefSeq - XM_006530531
RefSeq - XM_006530532
RefSeq - XM_006530533
RefSeq - XM_006530534
RefSeq - XM_006530535
RefSeq - XM_006530537
RefSeq - NM_199446
RefSeq Peptide - NP_955517
swissprot - E0CXM1
swissprot - F7DF70
swissprot - E0CY30
swissprot - E0CZ55
swissprot - Q7TSH2
swissprot - E0CX43
Ensembl - ENSMUSG00000036879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phkbENSDARG00000078284Danio rerio
 PHKBENSGALG00000004004Gallus gallus
 PHKBENSG00000102893Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phka2 / Q8BWJ3 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / P46019* / phosphorylase kinase regulatory subunit alpha 2*ENSMUSG0000003129536
Phka1 / P18826 / Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform / P46020* / phosphorylase kinase regulatory subunit alpha 1*ENSMUSG0000003405535


Protein motifs (from Interpro)
Interpro ID Name
 IPR008734  Phosphorylase kinase alpha/beta subunit
 IPR008928  Six-hairpin glycosidase superfamily
 IPR011613  GH15-like domain


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005964 phosphorylase kinase complex IEA
 cellular_componentGO:0016020 membrane IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000025537 Phkg1 / P07934 / Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform / Q16816* / phosphorylase kinase catalytic subunit gamma 1*  / complex
 ENSMUSG00000030815 Phkg2 / Q9DB30 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / P15735* / phosphorylase kinase catalytic subunit gamma 2*  / complex
 ENSMUSG00000034055 Phka1 / P18826 / Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform / P46020* / phosphorylase kinase regulatory subunit alpha 1*  / complex
 ENSMUSG00000031295 Phka2 / Q8BWJ3 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / P46019* / phosphorylase kinase regulatory subunit alpha 2*  / complex
 ENSMUSG00000036879 Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*  / complex
 ENSMUSG00000021069 Pygl / Q9ET01 / Glycogen phosphorylase, liver form / P06737* / glycogen phosphorylase L*  / reaction
 ENSMUSG00000032648 Pygm / Q9WUB3 / Glycogen phosphorylase, muscle form / P11217* / glycogen phosphorylase, muscle associated*  / reaction
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / complex






 

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