ENSMUSG00000025537


Mus musculus

Features
Gene ID: ENSMUSG00000025537
  
Biological name :Phkg1
  
Synonyms : P07934 / Phkg1 / Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform
  
Possible biological names infered from orthology : phosphorylase kinase catalytic subunit gamma 1 / Q16816
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: G1.3
Gene start: 129863421
Gene end: 129898549
  
Corresponding Affymetrix probe sets: 10534085 (MoGene1.0st)   1422315_x_at (Mouse Genome 430 2.0 Array)   1425164_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000026617
Ensembl peptide - ENSMUSP00000122040
Ensembl peptide - ENSMUSP00000117510
NCBI entrez gene - 18682     See in Manteia.
MGI - MGI:97579
RefSeq - NM_011079
RefSeq - XM_011240871
RefSeq Peptide - NP_035209
swissprot - D3Z472
swissprot - P07934
swissprot - D3Z1B5
Ensembl - ENSMUSG00000025537
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phkg1aENSDARG00000030604Danio rerio
 phkg1bENSDARG00000069498Danio rerio
 PHKG1ENSGALG00000002485Gallus gallus
 PHKG1ENSG00000164776Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Phkg2 / Q9DB30 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / P15735* / phosphorylase kinase catalytic subunit gamma 2*ENSMUSG0000003081562
Dclk1 / Q9JLM8 / Mus musculus doublecortin-like kinase 1 (Dclk1), transcript variant 12, mRNA. / O15075* / doublecortin like kinase 1*ENSMUSG0000002779731
Dclk2 / Q6PGN3 / Serine/threonine-protein kinase DCLK2 / Q8N568* / doublecortin like kinase 2*ENSMUSG0000002807830
Dclk3 / Q8BWQ5 / Serine/threonine-protein kinase DCLK3 / Q9C098* / doublecortin like kinase 3*ENSMUSG0000003250028
Stk33 / Q924X7 / Serine/threonine-protein kinase 33 / Q9BYT3* / serine/threonine kinase 33*ENSMUSG0000003102727
Dcx / O88809 / Neuronal migration protein doublecortin / O43602* / doublecortin*ENSMUSG000000312852


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR002291  Phosphorylase kinase, gamma catalytic subunit
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IBA
 biological_processGO:0005978 glycogen biosynthetic process IEA
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005964 phosphorylase kinase complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IBA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0050321 tau-protein kinase activity IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000034055 Phka1 / P18826 / Phosphorylase b kinase regulatory subunit alpha, skeletal muscle isoform / P46020* / phosphorylase kinase regulatory subunit alpha 1*  / complex
 ENSMUSG00000025537 Phkg1 / P07934 / Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform / Q16816* / phosphorylase kinase catalytic subunit gamma 1*  / complex
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / complex
 ENSMUSG00000036879 Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*  / complex
 ENSMUSG00000032648 Pygm / Q9WUB3 / Glycogen phosphorylase, muscle form / P11217* / glycogen phosphorylase, muscle associated*  / reaction






 

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