ENSG00000164776


Homo sapiens

Features
Gene ID: ENSG00000164776
  
Biological name :PHKG1
  
Synonyms : PHKG1 / phosphorylase kinase catalytic subunit gamma 1 / Q16816
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 7
Strand: -1
Band: p11.2
Gene start: 56080283
Gene end: 56092996
  
Corresponding Affymetrix probe sets: 207312_at (Human Genome U133 Plus 2.0 Array)   234729_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000389721
Ensembl peptide - ENSP00000378817
Ensembl peptide - ENSP00000397193
Ensembl peptide - ENSP00000445440
Ensembl peptide - ENSP00000441528
Ensembl peptide - ENSP00000297373
NCBI entrez gene - 5260     See in Manteia.
OMIM - 172470
RefSeq - XM_017012326
RefSeq - NM_001258459
RefSeq - NM_001258460
RefSeq - NM_006213
RefSeq - XM_005271772
RefSeq - XM_017012324
RefSeq - XM_017012325
RefSeq Peptide - NP_001245389
RefSeq Peptide - NP_006204
RefSeq Peptide - NP_001245388
swissprot - F6VCX5
swissprot - F8WD25
swissprot - A0A024RDL4
swissprot - Q16816
swissprot - C9JME8
swissprot - C9J2Q6
Ensembl - ENSG00000164776
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 phkg1aENSDARG00000030604Danio rerio
 phkg1bENSDARG00000069498Danio rerio
 PHKG1ENSGALG00000002485Gallus gallus
 Phkg1ENSMUSG00000025537Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PHKG2 / P15735 / phosphorylase kinase catalytic subunit gamma 2ENSG0000015687359
DCLK1 / O15075 / doublecortin like kinase 1ENSG0000013308328
DCLK2 / Q8N568 / doublecortin like kinase 2ENSG0000017039028
DCLK3 / Q9C098 / doublecortin like kinase 3ENSG0000016367327
STK33 / Q9BYT3 / serine/threonine kinase 33ENSG0000013041326
DCX / O43602 / doublecortinENSG000000772792


Protein motifs (from Interpro)
Interpro ID Name
 IPR000719  Protein kinase domain
 IPR002291  Phosphorylase kinase, gamma catalytic subunit
 IPR008271  Serine/threonine-protein kinase, active site
 IPR011009  Protein kinase-like domain superfamily
 IPR017441  Protein kinase, ATP binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process NAS
 biological_processGO:0005977 glycogen metabolic process IBA
 biological_processGO:0005978 glycogen biosynthetic process IEA
 biological_processGO:0005980 glycogen catabolic process TAS
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018105 peptidyl-serine phosphorylation IBA
 biological_processGO:0018107 peptidyl-threonine phosphorylation IBA
 biological_processGO:0035556 intracellular signal transduction IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005964 phosphorylase kinase complex IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004674 protein serine/threonine kinase activity IEA
 molecular_functionGO:0004689 phosphorylase kinase activity IEA
 molecular_functionGO:0005516 calmodulin binding IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0050321 tau-protein kinase activity IEA


Pathways (from Reactome)
Pathway description
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000198668 CALM1 / P0DP23 / calmodulin 1  / complex
 ENSG00000102893 PHKB / Q93100 / phosphorylase kinase regulatory subunit beta  / complex
 ENSG00000067177 PHKA1 / P46020 / phosphorylase kinase regulatory subunit alpha 1  / complex
 ENSG00000164776 PHKG1 / Q16816 / phosphorylase kinase catalytic subunit gamma 1  / complex
 ENSG00000068976 PYGM / P11217 / glycogen phosphorylase, muscle associated  / reaction
 ENSG00000100994 PYGB / P11216 / glycogen phosphorylase B  / reaction






 

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