ENSMUSG00000021069


Mus musculus

Features
Gene ID: ENSMUSG00000021069
  
Biological name :Pygl
  
Synonyms : Glycogen phosphorylase, liver form / Pygl / Q9ET01
  
Possible biological names infered from orthology : glycogen phosphorylase L / P06737
  
Species: Mus musculus
  
Chr. number: 12
Strand: -1
Band: C2
Gene start: 70190811
Gene end: 70231488
  
Corresponding Affymetrix probe sets: 10400844 (MoGene1.0st)   1417741_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000071231
Ensembl peptide - ENSMUSP00000125585
NCBI entrez gene - 110095     See in Manteia.
MGI - MGI:97829
RefSeq - NM_133198
RefSeq Peptide - NP_573461
swissprot - Q3UEJ6
swissprot - Q9ET01
Ensembl - ENSMUSG00000021069
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pyglENSDARG00000002197Danio rerio
 PYGLENSGALG00000012365Gallus gallus
 PYGLENSG00000100504Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pygb / Q8CI94 / Glycogen phosphorylase, brain form / P11216* / glycogen phosphorylase B*ENSMUSG0000003305979
Pygm / Q9WUB3 / Glycogen phosphorylase, muscle form / P11217* / glycogen phosphorylase, muscle associated*ENSMUSG0000003264878


Protein motifs (from Interpro)
Interpro ID Name
 IPR000811  Glycosyl transferase, family 35
 IPR011833  Glycogen/starch/alpha-glucan phosphorylase
 IPR035090  Phosphorylase pyridoxal-phosphate attachment site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0005975 carbohydrate metabolic process IEA
 biological_processGO:0005977 glycogen metabolic process IEA
 biological_processGO:0005980 glycogen catabolic process IEA
 biological_processGO:0006015 5-phosphoribose 1-diphosphate biosynthetic process IEA
 biological_processGO:0008152 metabolic process IEA
 biological_processGO:0042593 glucose homeostasis IEA
 biological_processGO:0070266 necroptotic process IGI
 cellular_componentGO:0005737 cytoplasm IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002060 purine nucleobase binding IEA
 molecular_functionGO:0003824 catalytic activity IEA
 molecular_functionGO:0004645 phosphorylase activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0008144 drug binding IEA
 molecular_functionGO:0008184 glycogen phosphorylase activity IEA
 molecular_functionGO:0016208 AMP binding IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0016757 transferase activity, transferring glycosyl groups IEA
 molecular_functionGO:0019842 vitamin binding IEA
 molecular_functionGO:0030170 pyridoxal phosphate binding IEA
 molecular_functionGO:0030246 carbohydrate binding IEA
 molecular_functionGO:0032052 bile acid binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0102250 linear malto-oligosaccharide phosphorylase activity IEA
 molecular_functionGO:0102499 SHG alpha-glucan phosphorylase activity IEA


Pathways (from Reactome)
Pathway description
Neutrophil degranulation
Glycogen breakdown (glycogenolysis)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / reaction
 ENSMUSG00000030815 Phkg2 / Q9DB30 / Phosphorylase b kinase gamma catalytic chain, liver/testis isoform / P15735* / phosphorylase kinase catalytic subunit gamma 2*  / reaction
 ENSMUSG00000031295 Phka2 / Q8BWJ3 / Phosphorylase b kinase regulatory subunit alpha, liver isoform / P46019* / phosphorylase kinase regulatory subunit alpha 2*  / reaction
 ENSMUSG00000036879 Phkb / Q7TSH2 / Phosphorylase b kinase regulatory subunit beta / Q93100* / phosphorylase kinase regulatory subunit beta*  / reaction
 ENSMUSG00000021069 Pygl / Q9ET01 / Glycogen phosphorylase, liver form / P06737* / glycogen phosphorylase L*  / complex






 

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