ENSMUSG00000091898


Mus musculus

Features
Gene ID: ENSMUSG00000091898
  
Biological name :Tnnc1
  
Synonyms : P19123 / Tnnc1 / Troponin C, slow skeletal and cardiac muscles
  
Possible biological names infered from orthology : P63316 / troponin C1, slow skeletal and cardiac type
  
Species: Mus musculus
  
Chr. number: 14
Strand: 1
Band: B
Gene start: 31208312
Gene end: 31211729
  
Corresponding Affymetrix probe sets: 10413726 (MoGene1.0st)   1418370_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000131991
Ensembl peptide - ENSMUSP00000128765
NCBI entrez gene - 21924     See in Manteia.
MGI - MGI:98779
RefSeq - NM_009393
RefSeq Peptide - NP_033419
swissprot - E9Q8P0
swissprot - P19123
Ensembl - ENSMUSG00000091898
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnnc1bENSDARG00000037539Danio rerio
 TNNC1ENSGALG00000001459Gallus gallus
 TNNC1ENSG00000114854Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tnnc2 / P20801 / Troponin C, skeletal muscle / P02585* / troponin C2, fast skeletal type*ENSMUSG0000001730065
Calm2 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM3* / P0DP25* / calmodulin 3*ENSMUSG0000003643848
Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*ENSMUSG0000000117548
Calm3 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM1* / P0DP23*ENSMUSG0000001937048
Calml3 / Q9D6P8 / Calmodulin-like protein 3 / P27482* / calmodulin like 3*ENSMUSG0000006313045
Cabp1 / Q9JLK7 / Calcium-binding protein 1 / Q9NZU7*ENSMUSG0000002954435
Calm4 / Q9JM83 / Calmodulin-4 / Q9NZT1* / CALML5* / calmodulin like 5*ENSMUSG0000003376535
Cabp4 / Q8VHC5 / Calcium-binding protein 4 / P57796*ENSMUSG0000002484234
Cabp5 / Q9JLK3 / Calcium-binding protein 5 / Q9NP86*ENSMUSG0000000564934
Cabp2 / calcium binding protein 2 / Q9NPB3*ENSMUSG0000002485733
Calml4 / Q91WQ9 / Calmodulin-like protein 4 / Q96GE6* / calmodulin like 4*ENSMUSG0000003224629
Calm5 / calmodulin 5 / CALML5* / Q9NZT1* / calmodulin like 5*ENSMUSG0000009926929


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0002086 diaphragm contraction IEA
 biological_processGO:0003009 skeletal muscle contraction IBA
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0010038 response to metal ion IEA
 biological_processGO:0014883 transition between fast and slow fiber IDA
 biological_processGO:0032972 regulation of muscle filament sliding speed IMP
 biological_processGO:0043462 regulation of ATPase activity IDA
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 cellular_componentGO:0005861 troponin complex IEA
 cellular_componentGO:0043292 contractile fiber IEA
 cellular_componentGO:1990584 cardiac Troponin complex IEA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0031013 troponin I binding IEA
 molecular_functionGO:0031014 troponin T binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IEA
 molecular_functionGO:0051015 actin filament binding IDA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026414 Tnnt2 / P50752 / Troponin T, cardiac muscle / P45379* / troponin T2, cardiac type*  / complex
 ENSMUSG00000064179 Tnnt1 / O88346 / troponin T1, skeletal, slow / P13805* / troponin T1, slow skeletal type*  / complex
 ENSMUSG00000026418 Tnni1 / Q9WUZ5 / Troponin I, slow skeletal muscle / P19237* / troponin I1, slow skeletal type*  / complex
 ENSMUSG00000035458 Tnni3 / P48787 / troponin I, cardiac 3 / P19429* / troponin I3, cardiac type*  / complex
 ENSMUSG00000031097 Tnni2 / P13412 / Troponin I, fast skeletal muscle / P48788* / troponin I2, fast skeletal type*  / complex






 

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