ENSMUSG00000031097


Mus musculus

Features
Gene ID: ENSMUSG00000031097
  
Biological name :Tnni2
  
Synonyms : P13412 / Tnni2 / Troponin I, fast skeletal muscle
  
Possible biological names infered from orthology : P48788 / troponin I2, fast skeletal type
  
Species: Mus musculus
  
Chr. number: 7
Strand: 1
Band: F5
Gene start: 142441808
Gene end: 142444410
  
Corresponding Affymetrix probe sets: 10559200 (MoGene1.0st)   1416889_at (Mouse Genome 430 2.0 Array)   1438608_at (Mouse Genome 430 2.0 Array)   1438609_x_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000101593
Ensembl peptide - ENSMUSP00000147719
Ensembl peptide - ENSMUSP00000122733
Ensembl peptide - ENSMUSP00000121819
Ensembl peptide - ENSMUSP00000101591
NCBI entrez gene - 21953     See in Manteia.
MGI - MGI:105070
RefSeq - XM_006508539
RefSeq - NM_009405
RefSeq Peptide - NP_033431
swissprot - A2A6J8
swissprot - A2A6K0
swissprot - P13412
swissprot - A0A1B0GRY8
Ensembl - ENSMUSG00000031097
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnni2a.1ENSDARG00000045592Danio rerio
 tnni2a.2ENSDARG00000005841Danio rerio
 tnni2a.3ENSDARG00000013752Danio rerio
 tnni2a.4ENSDARG00000029069Danio rerio
 tnni2b.1ENSDARG00000035958Danio rerio
 tnni2b.2ENSDARG00000029995Danio rerio
 TNNI2ENSGALG00000006591Gallus gallus
 TNNI2ENSG00000130598Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tnni1 / Q9WUZ5 / Troponin I, slow skeletal muscle / P19237* / troponin I1, slow skeletal type*ENSMUSG0000002641856
Tnni3 / P48787 / troponin I, cardiac 3 / P19429* / troponin I3, cardiac type*ENSMUSG0000003545853


Protein motifs (from Interpro)
Interpro ID Name
 IPR001978  Troponin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0006937 regulation of muscle contraction IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0060048 cardiac muscle contraction IBA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005861 troponin complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0031014 troponin T binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
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Allelic Composition: Tmem100tm1e.1(KOMP)Wtsi/Tmem100tm1e.1(KOMP)Wtsi
Genetic Background: C57BL/6N-Tmem100tm1e.1(KOMP)Wtsi/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026414 Tnnt2 / P50752 / Troponin T, cardiac muscle / P45379* / troponin T2, cardiac type*  / complex
 ENSMUSG00000064179 Tnnt1 / O88346 / troponin T1, skeletal, slow / P13805* / troponin T1, slow skeletal type*  / complex
 ENSMUSG00000017300 Tnnc2 / P20801 / Troponin C, skeletal muscle / P02585* / troponin C2, fast skeletal type*  / complex
 ENSMUSG00000091898 Tnnc1 / P19123 / Troponin C, slow skeletal and cardiac muscles / P63316* / troponin C1, slow skeletal and cardiac type*  / complex






 

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contact: otassy@igbmc.fr