ENSMUSG00000017300


Mus musculus

Features
Gene ID: ENSMUSG00000017300
  
Biological name :Tnnc2
  
Synonyms : P20801 / Tnnc2 / Troponin C, skeletal muscle
  
Possible biological names infered from orthology : P02585 / troponin C2, fast skeletal type
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: H3
Gene start: 164777161
Gene end: 164779967
  
Corresponding Affymetrix probe sets: 10489545 (MoGene1.0st)   1417464_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000099384
NCBI entrez gene - 21925     See in Manteia.
MGI - MGI:98780
RefSeq - NM_009394
RefSeq Peptide - NP_033420
swissprot - P20801
Ensembl - ENSMUSG00000017300
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:rp71-17i16.4ENSDARG00000095002Danio rerio
 tnnc2ENSDARG00000070835Danio rerio
 TNNC2ENSGALG00000006835Gallus gallus
 TNNC2ENSG00000101470Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Tnnc1 / P19123 / Troponin C, slow skeletal and cardiac muscles / P63316* / troponin C1, slow skeletal and cardiac type*ENSMUSG0000009189866
Calm2 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM3* / P0DP25* / calmodulin 3*ENSMUSG0000003643849
Calm3 / P0DP27 / P0DP28 / P0DP26 / Calmodulin-1 / CALM1* / P0DP23*ENSMUSG0000001937049
Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*ENSMUSG0000000117548
Calml3 / Q9D6P8 / Calmodulin-like protein 3 / P27482* / calmodulin like 3*ENSMUSG0000006313044
Cabp5 / Q9JLK3 / Calcium-binding protein 5 / Q9NP86*ENSMUSG0000000564936
Cabp2 / calcium binding protein 2 / Q9NPB3*ENSMUSG0000002485736
Calm4 / Q9JM83 / Calmodulin-4 / Q9NZT1* / CALML5* / calmodulin like 5*ENSMUSG0000003376536
Cabp1 / Q9JLK7 / Calcium-binding protein 1 / Q9NZU7*ENSMUSG0000002954435
Cabp4 / Q8VHC5 / Calcium-binding protein 4 / P57796*ENSMUSG0000002484235
Calm5 / calmodulin 5 / CALML5* / Q9NZT1* / calmodulin like 5*ENSMUSG0000009926930
Calml4 / Q91WQ9 / Calmodulin-like protein 4 / Q96GE6* / calmodulin like 4*ENSMUSG0000003224628


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IEA
 biological_processGO:0006937 regulation of muscle contraction IBA
 cellular_componentGO:0005861 troponin complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005509 calcium ion binding IBA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IBA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000026414 Tnnt2 / P50752 / Troponin T, cardiac muscle / P45379* / troponin T2, cardiac type*  / complex
 ENSMUSG00000064179 Tnnt1 / O88346 / troponin T1, skeletal, slow / P13805* / troponin T1, slow skeletal type*  / complex
 ENSMUSG00000026418 Tnni1 / Q9WUZ5 / Troponin I, slow skeletal muscle / P19237* / troponin I1, slow skeletal type*  / complex
 ENSMUSG00000035458 Tnni3 / P48787 / troponin I, cardiac 3 / P19429* / troponin I3, cardiac type*  / complex
 ENSMUSG00000031097 Tnni2 / P13412 / Troponin I, fast skeletal muscle / P48788* / troponin I2, fast skeletal type*  / complex






 

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