ENSG00000101470


Homo sapiens

Features
Gene ID: ENSG00000101470
  
Biological name :TNNC2
  
Synonyms : P02585 / TNNC2 / troponin C2, fast skeletal type
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 20
Strand: -1
Band: q13.12
Gene start: 45823214
Gene end: 45833745
  
Corresponding Affymetrix probe sets: 205388_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000361636
Ensembl peptide - ENSP00000361638
NCBI entrez gene - 7125     See in Manteia.
OMIM - 191039
RefSeq - NM_003279
RefSeq - XM_011529031
RefSeq Peptide - NP_003270
swissprot - C9J7T9
swissprot - P02585
Ensembl - ENSG00000101470
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 si:rp71-17i16.4ENSDARG00000095002Danio rerio
 tnnc2ENSDARG00000070835Danio rerio
 TNNC2ENSGALG00000006835Gallus gallus
 Tnnc2ENSMUSG00000017300Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNNC1 / P63316 / troponin C1, slow skeletal and cardiac typeENSG0000011485465
CALM3 / P0DP25 / calmodulin 3ENSG0000016001449
CALM1 / P0DP23 / calmodulin 1ENSG0000019866849
CALM2 / P0DP24 / calmodulin 2ENSG0000014393349
CALML3 / P27482 / calmodulin like 3ENSG0000017836341
CALML6 / Q8TD86 / calmodulin like 6ENSG0000016988537
CABP5 / Q9NP86 / calcium binding protein 5ENSG0000010550736
CABP4 / P57796 / calcium binding protein 4ENSG0000017554436
CABP2 / Q9NPB3 / calcium binding protein 2ENSG0000016779136
CABP1 / Q9NZU7 / calcium binding protein 1ENSG0000015778235
CALML5 / Q9NZT1 / calmodulin like 5ENSG0000017837232
CALML4 / Q96GE6 / calmodulin like 4ENSG0000012900727


Protein motifs (from Interpro)
Interpro ID Name
 IPR002048  EF-hand domain
 IPR011992  EF-hand domain pair
 IPR018247  EF-Hand 1, calcium-binding site


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IDA
 biological_processGO:0006937 regulation of muscle contraction TAS
 biological_processGO:0030049 muscle filament sliding TAS
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005861 troponin complex IDA
 molecular_functionGO:0003779 actin binding IDA
 molecular_functionGO:0005509 calcium ion binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0048306 calcium-dependent protein binding IBA
 molecular_functionGO:0051015 actin filament binding IBA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000118194 TNNT2 / P45379 / troponin T2, cardiac type  / complex
 ENSG00000130595 TNNT3 / P45378 / troponin T3, fast skeletal type  / complex
 ENSG00000105048 TNNT1 / P13805 / troponin T1, slow skeletal type  / complex
 ENSG00000129991 TNNI3 / P19429 / troponin I3, cardiac type  / complex
 ENSG00000159173 TNNI1 / P19237 / troponin I1, slow skeletal type  / complex
 ENSG00000130598 TNNI2 / P48788 / troponin I2, fast skeletal type  / complex






 

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