ENSG00000159173


Homo sapiens

Features
Gene ID: ENSG00000159173
  
Biological name :TNNI1
  
Synonyms : P19237 / TNNI1 / troponin I1, slow skeletal type
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 1
Strand: -1
Band: q32.1
Gene start: 201403768
Gene end: 201429866
  
Corresponding Affymetrix probe sets: 205177_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000451660
Ensembl peptide - ENSP00000451776
Ensembl peptide - ENSP00000477578
Ensembl peptide - ENSP00000337022
Ensembl peptide - ENSP00000354488
Ensembl peptide - ENSP00000356281
Ensembl peptide - ENSP00000451307
NCBI entrez gene - 7135     See in Manteia.
OMIM - 191042
RefSeq - NM_003281
RefSeq Peptide - NP_003272
swissprot - G3V489
swissprot - A0A087WT47
swissprot - P19237
swissprot - G3V4F8
swissprot - G3V3L5
Ensembl - ENSG00000159173
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 tnni1aENSDARG00000000474Danio rerio
 tnni1bENSDARG00000052708Danio rerio
 TNNI1ENSGALG00000000313Gallus gallus
 Tnni1ENSMUSG00000026418Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
TNNI3 / P19429 / troponin I3, cardiac typeENSG0000012999159
TNNI2 / P48788 / troponin I2, fast skeletal typeENSG0000013059854


Protein motifs (from Interpro)
Interpro ID Name
 IPR001978  Troponin


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0003009 skeletal muscle contraction IBA
 biological_processGO:0006942 regulation of striated muscle contraction NAS
 biological_processGO:0014883 transition between fast and slow fiber IEA
 biological_processGO:0030049 muscle filament sliding TAS
 biological_processGO:0055010 ventricular cardiac muscle tissue morphogenesis IEA
 biological_processGO:0060048 cardiac muscle contraction IBA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005861 troponin complex IEA
 molecular_functionGO:0003779 actin binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Striated Muscle Contraction


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSG00000114854 TNNC1 / P63316 / troponin C1, slow skeletal and cardiac type  / complex
 ENSG00000118194 TNNT2 / P45379 / troponin T2, cardiac type  / complex
 ENSG00000130595 TNNT3 / P45378 / troponin T3, fast skeletal type  / complex
 ENSG00000105048 TNNT1 / P13805 / troponin T1, slow skeletal type  / complex
 ENSG00000101470 TNNC2 / P02585 / troponin C2, fast skeletal type  / complex






 

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