ENSMUSG00000067220


Mus musculus

Features
Gene ID: ENSMUSG00000067220
  
Biological name :Cnga1
  
Synonyms : cGMP-gated cation channel alpha-1 / Cnga1 / P29974
  
Possible biological names infered from orthology : cyclic nucleotide gated channel alpha 1 / P29973
  
Species: Mus musculus
  
Chr. number: 5
Strand: -1
Band: C3.2
Gene start: 72603696
Gene end: 72644275
  
Corresponding Affymetrix probe sets: 10530503 (MoGene1.0st)   1432917_at (Mouse Genome 430 2.0 Array)   1451763_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000132329
Ensembl peptide - ENSMUSP00000143881
Ensembl peptide - ENSMUSP00000143377
Ensembl peptide - ENSMUSP00000084464
Ensembl peptide - ENSMUSP00000119886
NCBI entrez gene - 12788     See in Manteia.
MGI - MGI:88436
RefSeq - NM_007723
RefSeq - XM_006503709
RefSeq Peptide - NP_031749
swissprot - A0A0R4J1V3
swissprot - P29974
swissprot - A0A0G2JG06
Ensembl - ENSMUSG00000067220
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnga1ENSDARG00000012125Danio rerio
 si:dkey-22i16.2ENSDARG00000029898Danio rerio
 CNGA1ENSGALG00000014136Gallus gallus
 CNGA1ENSG00000198515Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Cnga3 / Q9JJZ8 / Cyclic nucleotide-gated cation channel alpha-3 / Q16281* / cyclic nucleotide gated channel alpha 3*ENSMUSG0000002611457
Cnga2 / Q62398 / Cyclic nucleotide-gated olfactory channel / Q16280* / cyclic nucleotide gated channel alpha 2*ENSMUSG0000000586457
Cnga4 / Q3UW12 / Cyclic nucleotide-gated cation channel alpha-4 / Q8IV77* / cyclic nucleotide gated channel alpha 4*ENSMUSG0000003089741
Cngb1 / cyclic nucleotide gated channel beta 1 / Q14028*ENSMUSG0000003178928
Cngb3 / Q9JJZ9 / Cyclic nucleotide-gated cation channel beta-3 / Q9NQW8* / cyclic nucleotide gated channel beta 3*ENSMUSG0000005649425
Hcn4 / hyperpolarization activated cyclic nucleotide gated potassium channel 4 / Q9Y3Q4*ENSMUSG0000003233822
Hcn1 / O88704 / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 / O60741* / hyperpolarization activated cyclic nucleotide gated potassium channel 1*ENSMUSG0000002173021
Hcn2 / O88703 / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / Q9UL51* / hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2*ENSMUSG0000002033120
Hcn3 / O88705 / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 / Q9P1Z3* / hyperpolarization activated cyclic nucleotide gated potassium channel 3*ENSMUSG0000002805119


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR005821  Ion transport domain
 IPR008936  Rho GTPase activation protein
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like
 IPR032406  Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
 IPR032945  cGMP-gated cation channel alpha-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0001750 photoreceptor outer segment IDA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IDA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042622 photoreceptor outer segment membrane IDA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005221 intracellular cyclic nucleotide activated cation channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0030553 cGMP binding IEA


Pathways (from Reactome)
Pathway description
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000067220 Cnga1 / P29974 / cGMP-gated cation channel alpha-1 / P29973* / cyclic nucleotide gated channel alpha 1*  / complex
 ENSMUSG00000001175 Calm1 / P0DP28 / P0DP26 / P0DP27 / Calmodulin-1 / P0DP23*  / reaction / complex






 

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