ENSGALG00000014136


Gallus gallus

Features
Gene ID: ENSGALG00000014136
  
Biological name :CNGA1
  
Synonyms : CNGA1 / Cyclic nucleotide-gated channel rod photoreceptor subunit alpha / Q90980
  
Possible biological names infered from orthology : cGMP-gated cation channel alpha-1 / cyclic nucleotide gated channel alpha 1 / P29973 / P29974
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 67010756
Gene end: 67015296
  
Corresponding Affymetrix probe sets: Gga.671.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046086
Ensembl peptide - ENSGALP00000022830
NCBI entrez gene - 396143     See in Manteia.
RefSeq - NM_205220
RefSeq Peptide - NP_990551
swissprot - Q90980
swissprot - A0A1D5P0B1
Ensembl - ENSGALG00000014136
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 cnga1ENSDARG00000012125Danio rerio
 si:dkey-22i16.2ENSDARG00000029898Danio rerio
 CNGA1ENSG00000198515Homo sapiens
 Cnga1ENSMUSG00000067220Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
CNGA3 / cyclic nucleotide-gated channel cone photoreceptor subunit alpha / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSGALG0000003982665
CNGA2 / cyclic nucleotide gated channel alpha 2 / Q16280* / Q62398* / Cyclic nucleotide-gated olfactory channel *ENSGALG0000000728252
CNGA4 / cyclic nucleotide gated channel alpha 4 / Q3UW12* / Q8IV77* / Cyclic nucleotide-gated cation channel alpha-4 *ENSGALG0000002270430
CNGB1 / cyclic nucleotide gated channel beta 1 / Q14028*ENSGALG0000004264728
CNGB3 / cyclic nucleotide gated channel beta 3 / Q9JJZ9* / Q9NQW8* / Cyclic nucleotide-gated cation channel beta-3 *ENSGALG0000003764427
HCN4 / hyperpolarization activated cyclic nucleotide gated potassium channel 4 / Q9Y3Q4*ENSGALG0000000176424
HCN1 / hyperpolarization activated cyclic nucleotide gated potassium channel 1 / O60741* / O88704* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 *ENSGALG0000001487522
HCN2 / hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 / O88703* / Q9UL51* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 *ENSGALG0000000134221
HCN3 / hyperpolarization activated cyclic nucleotide gated potassium channel 3 / O88705* / Q9P1Z3* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 *ENSGALG0000003365320


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR005821  Ion transport domain
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like
 IPR032406  Cyclic nucleotide-gated channel, C-terminal leucine zipper domain
 IPR032945  cGMP-gated cation channel alpha-1


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0007601 visual perception IEA
 biological_processGO:0042391 regulation of membrane potential IBA
 biological_processGO:0050896 response to stimulus IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0098655 cation transmembrane transport IEA
 cellular_componentGO:0001750 photoreceptor outer segment IEA
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0042622 photoreceptor outer segment membrane IEA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005221 intracellular cyclic nucleotide activated cation channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0030552 cAMP binding IEA


Pathways (from Reactome)
Pathway description
Activation of the phototransduction cascade
Inactivation, recovery and regulation of the phototransduction cascade


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000010023 CALM2 / P62149 / Calmodulin / Calm3* / CALM1* / P0DP23* / P0DP26* / P0DP27* / P0DP28* / calmodulin 1*  / reaction / complex
 ENSGALG00000014136 CNGA1 / Q90980 / Cyclic nucleotide-gated channel rod photoreceptor subunit alpha / P29973* / P29974* / cGMP-gated cation channel alpha-1 * / cyclic nucleotide gated channel alpha 1*  / complex






 

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