ENSGALG00000001342


Gallus gallus

Features
Gene ID: ENSGALG00000001342
  
Biological name :HCN2
  
Synonyms : HCN2 / hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2
  
Possible biological names infered from orthology : O88703 / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 / Q9UL51
  
Species: Gallus gallus
  
Chr. number: 28
Strand: 1
Band:
Gene start: 2711394
Gene end: 2723081
  
Corresponding Affymetrix probe sets: GgaAffx.891.1.S1_at (Chicken Array)   GgaAffx.891.2.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000002046
NCBI entrez gene - 770384     See in Manteia.
RefSeq - XM_003642867
swissprot - F1NLU5
Ensembl - ENSGALG00000001342
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 HCN2ENSG00000099822Homo sapiens
 Hcn2ENSMUSG00000020331Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HCN4 / hyperpolarization activated cyclic nucleotide gated potassium channel 4 / Q9Y3Q4*ENSGALG0000000176462
HCN1 / hyperpolarization activated cyclic nucleotide gated potassium channel 1 / O60741* / O88704* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 *ENSGALG0000001487557
HCN3 / hyperpolarization activated cyclic nucleotide gated potassium channel 3 / O88705* / Q9P1Z3* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 3 *ENSGALG0000003365352
CNGA1 / Q90980 / Cyclic nucleotide-gated channel rod photoreceptor subunit alpha / P29973* / P29974* / cGMP-gated cation channel alpha-1 * / cyclic nucleotide gated channel alpha 1*ENSGALG0000001413615
CNGA3 / cyclic nucleotide-gated channel cone photoreceptor subunit alpha / Q16281* / Q9JJZ8* / cyclic nucleotide gated channel alpha 3* / Cyclic nucleotide-gated cation channel alpha-3 *ENSGALG0000003982615
CNGB1 / cyclic nucleotide gated channel beta 1 / Q14028*ENSGALG0000004264714
CNGB3 / cyclic nucleotide gated channel beta 3 / Q9JJZ9* / Q9NQW8* / Cyclic nucleotide-gated cation channel beta-3 *ENSGALG0000003764413
CNGA2 / cyclic nucleotide gated channel alpha 2 / Q16280* / Q62398* / Cyclic nucleotide-gated olfactory channel *ENSGALG0000000728212
CNGA4 / cyclic nucleotide gated channel alpha 4 / Q3UW12* / Q8IV77* / Cyclic nucleotide-gated cation channel alpha-4 *ENSGALG0000002270410


Protein motifs (from Interpro)
Interpro ID Name
 IPR000595  Cyclic nucleotide-binding domain
 IPR003938  Potassium channel, voltage-dependent, EAG/ELK/ERG
 IPR005821  Ion transport domain
 IPR013621  Ion transport N-terminal
 IPR014710  RmlC-like jelly roll fold
 IPR018488  Cyclic nucleotide-binding, conserved site
 IPR018490  Cyclic nucleotide-binding-like


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006811 ion transport IEA
 biological_processGO:0006813 potassium ion transport IEA
 biological_processGO:0034765 regulation of ion transmembrane transport IEA
 biological_processGO:0035725 sodium ion transmembrane transport IEA
 biological_processGO:0042391 regulation of membrane potential IEA
 biological_processGO:0055085 transmembrane transport IEA
 biological_processGO:0071320 cellular response to cAMP IEA
 biological_processGO:0071321 cellular response to cGMP IEA
 biological_processGO:0071805 potassium ion transmembrane transport IEA
 biological_processGO:0098719 sodium ion import across plasma membrane IEA
 biological_processGO:1990573 potassium ion import across plasma membrane IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0005887 integral component of plasma membrane IEA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0098855 HCN channel complex IEA
 molecular_functionGO:0005216 ion channel activity IEA
 molecular_functionGO:0005222 intracellular cAMP activated cation channel activity IEA
 molecular_functionGO:0005244 voltage-gated ion channel activity IEA
 molecular_functionGO:0005248 voltage-gated sodium channel activity IEA
 molecular_functionGO:0005249 voltage-gated potassium channel activity IBA
 molecular_functionGO:0005267 potassium channel activity IEA
 molecular_functionGO:0042802 identical protein binding IEA


Pathways (from Reactome)
Pathway description
HCN channels


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSGALG00000001342 HCN2 / hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2 / O88703* / Q9UL51* / Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 *  / complex






 

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