ENSMUSG00000032285


Mus musculus

Features
Gene ID: ENSMUSG00000032285
  
Biological name :Dnaja4
  
Synonyms : Dnaja4 / Mus musculus DnaJ heat shock protein family (Hsp40) member A4 (Dnaja4), transcript variant 1, mRNA. / Q9JMC3
  
Possible biological names infered from orthology : DnaJ heat shock protein family (Hsp40) member A4 / Q8WW22
  
Species: Mus musculus
  
Chr. number: 9
Strand: 1
Band: A5.3
Gene start: 54698873
Gene end: 54716315
  
Corresponding Affymetrix probe sets: 10585428 (MoGene1.0st)   1418591_at (Mouse Genome 430 2.0 Array)   1418592_at (Mouse Genome 430 2.0 Array)   1434196_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000070413
Ensembl peptide - ENSMUSP00000112520
Ensembl peptide - ENSMUSP00000119602
NCBI entrez gene - 58233     See in Manteia.
MGI - MGI:1927638
RefSeq - XM_006511325
RefSeq - NM_001357875
RefSeq - NM_021422
RefSeq Peptide - NP_001344804
RefSeq Peptide - NP_067397
swissprot - Q9JMC3
swissprot - D3Z1U5
Ensembl - ENSMUSG00000032285
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 DNAJA4ENSDARG00000051762Danio rerio
 DNAJA4ENSGALG00000036850Gallus gallus
 DNAJA4ENSG00000140403Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Dnaja1 / P63037 / DnaJ homolog subfamily A member 1 / P31689* / DnaJ heat shock protein family (Hsp40) member A1*ENSMUSG0000002841073
Dnaja2 / Q9QYJ0 / DnaJ homolog subfamily A member 2 / O60884* / DnaJ heat shock protein family (Hsp40) member A2*ENSMUSG0000003170154
Q99KV1 / Dnajb11 / DnaJ homolog subfamily B member 11 / Q9UBS4* / AC068631.2* / DnaJ heat shock protein family (Hsp40) member B11*ENSMUSG0000000446031


Protein motifs (from Interpro)
Interpro ID Name
 IPR001305  Heat shock protein DnaJ, cysteine-rich domain
 IPR001623  DnaJ domain
 IPR002939  Chaperone DnaJ, C-terminal
 IPR008971  HSP40/DnaJ peptide-binding
 IPR012724  Chaperone DnaJ
 IPR018253  DnaJ domain, conserved site
 IPR036410  Heat shock protein DnaJ, cysteine-rich domain superfamily
 IPR036869  Chaperone J-domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0009408 response to heat IEA
 biological_processGO:0042026 protein refolding IEA
 biological_processGO:0090084 negative regulation of inclusion body assembly IEA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0016020 membrane ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051082 unfolded protein binding ISO
 molecular_functionGO:0051087 chaperone binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0005344 increased circulating bilirubin level "greater than the normal concentration in the blood of this yellow heme breakdown product" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:85204]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

 MP:0005560 decreased circulating glucose level "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cecr2tm2b(EUCOMM)Hmgu/Cecr2+
Genetic Background: C57BL/6N-Cecr2tm2b(EUCOMM)Hmgu/Tcp

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000023944 P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*  / reaction
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / reaction
 ENSMUSG00000091971 Q61696 / Hspa1a / Heat shock 70 kDa protein 1A / HSPA1B* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / complex / reaction
 ENSMUSG00000090877 P17879 / Hspa1b / Heat shock 70 kDa protein 1B / HSPA1A* / P0DMV8* / P0DMV9* / heat shock protein family A (Hsp70) member 1B* / heat shock protein family A (Hsp70) member 1A*  / complex / reaction
 ENSMUSG00000032285 Dnaja4 / Q9JMC3 / Mus musculus DnaJ heat shock protein family (Hsp40) member A4 (Dnaja4), transcript variant 1, mRNA. / Q8WW22* / DnaJ heat shock protein family (Hsp40) member A4*  / complex
 ENSMUSG00000015656 Hspa8 / P63017 / Heat shock cognate 71 kDa protein / P11142* / heat shock protein family A (Hsp70) member 8*  / reaction / complex
 ENSMUSG00000024966 Stip1 / Q60864 / Stress-induced-phosphoprotein 1 / P31948*  / reaction






 

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