| MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0000558 | abnormal tibia morphology | "atructural anomaly of the medial and larger of the two bones of the lower leg" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0000627 | abnormal mammary gland morphology | "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183] |
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Allelic Composition: Tln1tm4.1Crit/Tln1tm4.1Crit,Tg(Pf4-icre)Q3Rsko/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
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| MP:0000628 | abnormal mammary gland development | "aberration in the differentiation of the mammary gland during early embryogenesis or during sexual maturity" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0000662 | abnormal branching of the mammary ductal tree | "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm2Omc/Pgrtm2Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
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| MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm3(rtTA2S*M2)Lyd/Pgrtm3(rtTA2S*M2)Lyd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0001120 | abnormal uterus morphology | "malformation or absence of the female muscular organ of gestation" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001123 | dilated uterus | "stretched or enlarged female muscular organ of gestation" [J:50844] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
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| MP:0001134 | absent corpora lutea | "missing yellow endocrine body formed in the ovary after follicle rupture" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0001272 | increased metastatic potential | |
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Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001376 | abnormal mating receptivity | "deviation from the normal cycle or inability of females to respond favorably to males that initiate sexual behavior" [J:51468] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
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| MP:0001619 | abnormal vascular permeability | "anomaly in the ability of the blood vessels to permit the passage of substances such as fluid, heat, or gases" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Pgrtm1.2Mlia/Pgrtm1.2Mlia
Genetic Background: involves: 129X1/SvJ
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| MP:0001634 | internal hemorrhage | "blood loss in the interior of the body due to vessel rupture or dysmorphology " [J:23170] |
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Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001672 | abnormal embryogenesis/ development | "anomaly in the establishment of the characteristic configuration of the embryonic body" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001711 | abnormal placenta | |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001728 | failure of implantation | "inability of the blastocyst to attach to the endometrium of the uterus" [J:38772] |
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Allelic Composition: Bmp5cfe-se7J/Bmp5cfe-se7J
Genetic Background: involves: 129S7/SvEvBrd * BALB/cJ
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| MP:0001729 | impaired implantation | "impaired ability of the blastocyst to attach to the endometrium of the uterus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Pgrtm1.2Mlia/Pgrtm1.2Mlia
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0001881 | abnormal mammary gland physiology | "aberrant function of of the milk-secreting gland that lies within the breast" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
Allelic Composition: Pgrtm4.2Lyd/Pgrtm4.2Lyd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * FVB/N
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| MP:0001882 | abnormal lactation | "atypical production of milk from the mammary gland" [J:51296] |
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Allelic Composition: Gria2tm1Rod/Gria2tm1Rod,Gria3tm1Zpj/Y
Genetic Background: involves: 129/Sv * C57BL/6
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| MP:0001919 | abnormal reproductive system physiology | "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1(PyVT)Arge/Actb+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv
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| MP:0001923 | reduced female fertility | "reduced ability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ror1tm1.1Meg/Ror1tm1.1Meg,Ror2tm1.1Meg/Ror2tm1.1Meg
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Omc/Pgrtm1Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm1.2Mlia/Pgrtm1.2Mlia
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Allelic Composition: Pgrtm3(rtTA2S*M2)Lyd/Pgrtm3(rtTA2S*M2)Lyd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Wnt7atm1.1Tesp/Wnt7atm1.1Tesp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Ncoa6tm3Jxu/Ncoa6tm3Jxu,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
Allelic Composition: Nr2f2tm2.1Tsa/Nr2f2tm2.1Tsa,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129S7/SvEvBrd * 129X1/SvJ
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| MP:0001928 | abnormal ovulation | "aberration in the release of an ovum from a rupturing Graafin follicle, normally regulated by a surge in lutenizing hormone" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm1.2Mlia/Pgrtm1.2Mlia
Genetic Background: involves: 129 * C57BL/6J
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| MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ror1tm1.1Meg/Ror1tm1.1Meg,Ror2tm1.1Meg/Ror2tm1.1Meg
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0002014 | papilloma | "benign epithelial tumor" [J:47225] |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
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| MP:0002016 | ovarian cysts | "cystic ovary; usually refers to a benign growth" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:35782] |
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Allelic Composition: Crb1tm1Wij/Crb1+,Crb2tm1.1Wij/Crb2tm1.1Wij,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL
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| MP:0002053 | decreased incidence of induced tumors | "reduced frequency of tumor incidence induced by a carcinogen or mutagen" [J:56886] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
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| MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm1.1Mlia/Pgrtm1.1Mlia
Genetic Background: involves: 129 * C57BL/6J
Allelic Composition: Pgrtm1.1(cre)Shah/?
Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Pgrtm2Shah/Pgrtm2Shah
Genetic Background: involves: 129S/SvEv * C57BL/6J
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| MP:0002566 | abnormal sexual interaction | "altered initiation, failure of initiation or incomplete mating behavior" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Actbtm1(PyVT)Arge/Actb+,Waptm1(cre)Arge/Wap+
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm3(rtTA2S*M2)Lyd/Pgrtm3(rtTA2S*M2)Lyd
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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| MP:0002676 | uterine hyperplasia | "increased size of the uterus due to increased cell number" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Omc/Pgrtm1Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Pgrtm1Lyd/Pgrtm1Lyd
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0002773 | decreased circulating luteinizing hormone level | "lower than normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35132, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0003009 | abnormal cytokine secretion | "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator] |
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Allelic Composition: Il18tm1Aki/Il18tm1Aki
Genetic Background: B6.129P2-Il18tm1Aki
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| MP:0003058 | increased insulin secretion | "greater than normal release of this hormone secreted by beta cells of the pancreas, that promotes glucose utilization, protein synthesis, and the formation and storage of neutral lipids " [MeSH:National Library of Medicine - Medical Subject Headings, 2003, RGD:Rat Genome Database submission] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0003356 | impaired lutenization | "atypical transformation of the mature ovarian follicle and its theca interna into a corpus luteum after ovulation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:57854, J:43075] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
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| MP:0003570 | uterine leiomyoma | "a benign tumor derived from the smooth muscle tissue of the uterus" [ncbi:Matthew Mailman, NCBI request, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0003572 | abnormal uterus development | "abnormal morphogenesis of the female muscular organ of gestation" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Zic2em5Bend/Zic2+
Genetic Background: involves: C3H/HeH
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| MP:0003574 | abnormal oviduct morphology | "malformation of the tube through which the ova pass from the ovary to the uterus" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Crb1tm1Wij/Crb1+,Crb2tm1.1Wij/Crb2tm1.1Wij,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL
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| MP:0003638 | abnormal response/metabolism to endogenous compounds | "altered ability or inability to metabolize or respond to substances normally present in the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0003645 | increased number of pancreatic beta cells | "greater than normal number of the cells of the pancreas that secrete insulin" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0003845 | abnormal decidualization | "disrupted proliferation, differentiation or transformation of endometrial stromal cells into decidual cells in the maternal uterus following embryo implantation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:43609, J:48920] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Omc/Pgrtm1Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
Allelic Composition: Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Allelic Composition: Ncoa1tm1Bwo/Ncoa1tm1Bwo,Ncoa2tm1.1Ipc/Ncoa2tm1.1Ipc,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129/Sv * 129S1/Sv * 129S2/SvPas * 129X1/SvJ
Allelic Composition: Ncoa6tm3Jxu/Ncoa6tm3Jxu,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
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| MP:0003967 | abnormal follicle stimulating hormone level | |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0004014 | abnormal uterine environment | "anomaly or inability of the uterus to support embryonic development" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Pgrtm1Omc/Pgrtm1Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6J
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| MP:0004148 | increased cortical bone thickness | "thicker than normal superficial layer of compact bone" [brs:Beverly Richards-Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0004256 | abnormal maternal decidual layer morphology | "anomaly in the structure of the maternal uterine-derived portion of the placenta" [PMID:11433360] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ror1tm1.1Meg/Ror1tm1.1Meg,Ror2tm1.1Meg/Ror2tm1.1Meg
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004868 | endometrial carcinoma | "malignant neoplasm arising from the endometrial tissue" [RGD:Rat Genome Database submission] |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
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| MP:0004883 | abnormal blood vessel healing | "anomaly in the repair process of blood vessels after injury" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0004896 | abnormal endometrium morphology | "any structural anomaly of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MESH:A05.360.319.679.490, MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0004902 | abnormal uterus size | "anomaly in the size of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0004904 | increased uterus weight | "increase in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
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| MP:0004905 | decreased uterus weight | "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0004906 | enlarged uterus | |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0004982 | abnormal osteoclast morphology | "any structural anomaly of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0005124 | increased circulating prolactin level | "greater than expected blood concentration of the hormone that stimulates milk secretion " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0005185 | decreased circulating progesterone level | "less than the normal blood concentration of this antiestrogenic steroid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
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Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0005292 | improved glucose tolerance | "better than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin sensitivity; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0005296 | abnormal humerus morphology | "malformation of the bone of the forelimb that articulates with the scapula above and the radius and ulna below" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0005489 | vascular smooth muscle cell hyperplasia | "increased numbers of smooth muscle cells in the vascular wall" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:48446] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0005491 | islet cell hyperplasia | "increased numbers cells within the structures that are scattered throughout the pancreas and comprise its endocrine portion" [J:48446, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0005560 | decreased circulating glucose level | "less than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [RGD:Rat Genome Database submission, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0005605 | increased bone mass | "an increase in the total amount of bone tissue contained in the skeleton" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0006269 | abnormal mammary gland growth during pregnancy | "anomaly in the extensive and rapid branching of the mammary ducts, expansion of mammary epithelium in the stroma between the ducts with or without abnormalities in nipple maturation " [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Pgrtm2Omc/Pgrtm2Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0008000 | ovary tumor | "presence of abnormal rapidly proliferating cells in the ovary, usually in the form of a distinct mass" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Crb1tm1Wij/Crb1+,Crb2tm1.1Wij/Crb2tm1.1Wij,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * C57BL/6JOlaHsd * SJL
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| MP:0008014 | lung tumor | "presence of abnormal, rapidly proliferating cells on the lung usually in the form of a distinct mass" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0008256 | abnormal myometrium morphology | "any structural anomaly of the smooth muscle coat of the uterus, which forms the main mass of the organ and surrounds and supports the endometrium" [MESH:A02.633.570.500, MGI:brs "Beverly Richards-Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0008271 | abnormal bone ossification | "any anomaly in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [GO:0001503] |
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Allelic Composition: Stk3tm1.1Yy/Stk3tm1Yy,Stk4tm1.1Yy/Stk4tm1.1Yy,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: C57BL/6 * CBA * DBA
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| MP:0008869 | anovulation | "complete failure of ovum to be released from an ovarian follicle" [MESH:C13.351.500.056.630.050, MGI:mnk "Michelle Knowlton, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Pgrtm4.2Lyd/Pgrtm4.2Lyd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * FVB/N
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| MP:0008870 | increased mature ovarian follicle number | "than normal numbers of spheroid cell aggregations in the ovary containing the ovum" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
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| MP:0008876 | decreased uterine NK cell number | "reduced number of the uterine subset of the non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"] |
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Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0008995 | early reproductive senescence | "loss of reproductive capacity occurring at an earlier than expected age" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0009080 | uterus inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
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| MP:0009082 | uterus cysts | "presence of fluid-filled structures inside the lumen of the uterus; usually refers to benign growths" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0009088 | thin uterine horn | "reduced thickness of either one of the pair of tubular extensions from the uterine body where the uterus and the uterine tubes meet" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0009091 | endometrium hypoplasia | "underdevelopment or reduced size, usually due to a reduced number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Phbtm1.1Bwo/Phbtm1.1Bwo,Pgrtm2(cre)Lyd/?
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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| MP:0009092 | endometrium hyperplasia | "overdevelopment or increased size, usually due an increased number of cells, of the glandular mucous membrane lining of the uterine cavity that is hormonally responsive during the estrous/menstrual cycle and during pregnancy" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu,Trp53tm1Brn/Trp53tm1Brn
Genetic Background: involves: 129 * C57BL/6
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Apctm1Rsmi/Apctm1Rsmi,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
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| MP:0009094 | abnormal endometrial gland morphology | "any structural anomaly of the numerous simple or branched tubular glands lined by ciliated columnar epithelium and found in the mucus membrane of the uterus which secrete mucus, lipids, glycogen, and protein; endometrial glands and their secretions (termed histotroph) are critical regulators of peri-implantation embryo survival and implantation as well as establishment of uterine receptivity" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0009097 | absent endometrial glands | "absence of the simple or branched tubular uterine glands" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Wnt7atm1.1Tesp/Wnt7atm1.1Tesp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
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| MP:0009209 | abnormal internal female genitalia morphology | "any structural anomaly of the internal feminine genital organs, including the ovaries, uterine tubes, uterus, uterine cervix, and vagina" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Apctm1Rsmi/Apctm1Rsmi,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0009251 | enlarged endometrial glands | "increase in the average size of the simple or branched tubular glands located in the mucous membrane of the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Zfpm2tm1Sho/Zfpm2tm1Sho,Tg(Myh6-Zfpm2)1Sho/0
Genetic Background: involves: 129S1/Sv
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0009347 | increased cancellous bone thickness | "thicker than normal bone with a lattice-like or spongy structure" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0009352 | impaired spacing of implantation sites | "in organisms which give birth to multiple offspring in one litter, blastocysts fail to implant at intervals conducive to the formation of a normal enveloping membrane or decidua for each conceptus from the epithelial tissue of the endometrium lining of the uterus" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009353 | twin decidual capsule | "two embryos share one decidual membrane" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009503 | abnormal mammary gland duct morphology | "any structural anomaly of the canals that lead from the lobes of the mammary gland to the tip of the nipple and are responsible for carrying milk toward the nipple in a lactating female" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Tln1tm4.1Crit/Tln1tm4.1Crit,Tg(Pf4-icre)Q3Rsko/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6
Allelic Composition: Phb2tm2.1Katz/Phb2tm2.1Katz,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009504 | abnormal mammary gland epithelium morphology | "any structural anomaly of the epithelial layer of the luminal surfaces of the mammary gland" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm2Omc/Pgrtm2Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0009506 | abnormal mammary gland alveolus morphology | "any structural anomaly of the sac-like structure of the mammary gland that secretes milk after pregnancy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm2Omc/Pgrtm2Omc
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0009662 | abnormal uterine receptivity | "any alteration in the time sensitive process of uterine differentiation that occurs in response to implantation competent blastocysts and precedes and is necessary for embryo implantation" [PMID:10882512 "Carson DD, et al, Embryo implantation Dev Biol. 2000 Jul 15;223(2):217-37."] |
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Allelic Composition: Ncoa6tm3Jxu/Ncoa6tm3Jxu,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
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| MP:0009663 | abnormal uterine-embryonic axis | "any anomaly in the process whereby the implantation chamber orients in the uterus in response to decidual growth to insure correct alignment of the embryo to the uterus" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:10882512 "Carson DD, et al, Embryo implantation Dev Biol. 2000 Jul 15;223(2):217-37."] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009664 | abnormal luminal closure | "an anomaly in the degree to which (for each species) the uterine epithelium closes over and makes contact with, and secures an implanting blastocyst" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:10882512 "Carson DD, et al, Embryo implantation Dev Biol. 2000 Jul 15;223(2):217-37."] |
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Allelic Composition: Ncoa6tm3Jxu/Ncoa6tm3Jxu,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129/Sv * C57BL/6 * SJL
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| MP:0009666 | abnormal embryo attachment | "any anomaly in the process whereby the blastocyst anchors to the uterine luminal epithelium and cannot be dislodged by flushing" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:10882512 "Carson DD, et al, Embryo implantation Dev Biol. 2000 Jul 15;223(2):217-37."] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ror1tm1.1Meg/Ror1tm1.1Meg,Ror2tm1.1Meg/Ror2tm1.1Meg
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0009669 | abnormal postimplantation uterine environment | "failure of the uterus to undergo the changes necessary to support pregnancy following implantation of the embryo" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", PMID:10882512 "Carson DD, et al, Embryo implantation Dev Biol. 2000 Jul 15;223(2):217-37."] |
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Allelic Composition: Wnt7atm1.1Tesp/Wnt7atm1.1Tesp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * SJL
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| MP:0009671 | abnormal uterus physiology | "any anomaly in normal cyclical changes not due to anatomical defect" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
Allelic Composition: Pgrtm4.2Lyd/Pgrtm4.2Lyd
Genetic Background: involves: 129S4/SvJaeSor * 129S7/SvEvBrd * C57BL/6 * FVB/N
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ
Allelic Composition: Wnt11tm1.1Khay/Wnt11tm1.2Khay,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Pgrtm1.2Mlia/Pgrtm1.2Mlia
Genetic Background: involves: 129X1/SvJ
Allelic Composition: Pgrtm1.1Mlia/Pgrtm1.1Mlia,Tg(Cdh5-cre)7Mlia/0
Genetic Background: involves: 129X1/SvJ * FVB/N
Allelic Composition: Gt(ROSA)26Sortm1(CAG-Errfi1)Jwj/?,Pgrtm2(cre)Lyd/Pgr+,Ptentm1Hwu/Ptentm1Hwu
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6
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| MP:0010039 | abnormal trophoblast giant cell proliferation | "abnormality in the expansion rate of the trophoblast giant cell population by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0010174 | decreased mammary gland epithelium proliferation | "decrease in the expansion rate of the cells of the mammary gland epithelium by cell division" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Pgrtm1Bwo/Pgrtm1Bwo
Genetic Background: involves: 129S7/SvEvBrd
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| MP:0010287 | increased reproductive system tumor incidence | "greater than the expected number of tumors originating in the reproductive system in a given population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Apctm1Rsmi/Apctm1Rsmi,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0011521 | decreased placental labyrinth size | "reduction in the size of the structure where embryonic blood vessels are surrounded by trophoblast cells and maternal blood" [MGI:csmith] |
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Allelic Composition: Gt(ROSA)26Sortm1(CAG-Wnt5a,-AcGFP)Skde/Gt(ROSA)26Sor+,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: Pgrtm2(cre)Lyd/Pgr+,Wnt5atm1.1Tpy/Wnt5atm1.1Tpy
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
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| MP:0011819 | increased pancreatic beta cell proliferation | "increase in the ability of the cells that secrete insulin and are located towards the center of the islets of Langerhans in the pancreas to undergo expansion by cell division" [CL:0000169] |
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL
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| MP:0012411 | increased granulosa cell tumor incidence | "greater than the expected number of neoplasms derived from somatic cells of the sex cord in the ovary a given population in a given time period" [http://orcid.org/0000-0001-5208-3432] |
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Allelic Composition: Apctm1Rsmi/Apctm1Rsmi,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6J
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| MP:0013401 | increased endometrial gland number | "greater than normal numbers of the simple or branched tubular glands found in the mucus membrane of the uterus" [MGI:Anna] |
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Allelic Composition: Errfi1tm1Jwj/Errfi1tm1Jwj,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Wnt11tm1.1Khay/Wnt11tm1.2Khay,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129P2/OlaHsd * 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Tsc2tm1.1Mjg/Tsc2tm1.1Mjg,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ
Allelic Composition: Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
Allelic Composition: Pgrmc1tm1.1Jjp/Pgrmc1tm1.1Jjp,Pgrmc2tm1.1Jjp/Pgrmc2tm1.1Jjp,Pgrtm2(cre)Lyd/Pgr+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J
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