ENSMUSG00000028341


Mus musculus

Features
Gene ID: ENSMUSG00000028341
  
Biological name :Nr4a3
  
Synonyms : Nr4a3 / Nuclear receptor subfamily 4 group A member 3 / Q9QZB6
  
Possible biological names infered from orthology : Q92570
  
Species: Mus musculus
  
Chr. number: 4
Strand: 1
Band: B1
Gene start: 48045153
Gene end: 48086447
  
Corresponding Affymetrix probe sets: 10504838 (MoGene1.0st)   1421079_at (Mouse Genome 430 2.0 Array)   1421080_at (Mouse Genome 430 2.0 Array)   1438796_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000030025
Ensembl peptide - ENSMUSP00000121455
NCBI entrez gene - 18124     See in Manteia.
MGI - MGI:1352457
RefSeq - XM_006537658
RefSeq - NM_015743
RefSeq - XM_006537656
RefSeq - XM_006537657
RefSeq Peptide - NP_056558
swissprot - F6R7A2
swissprot - Q9QZB6
Ensembl - ENSMUSG00000028341
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 nr4a3ENSDARG00000055854Danio rerio
 NR4A3ENSGALG00000013568Gallus gallus
 NR4A3ENSG00000119508Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Nr4a2 / Q06219 / Nuclear receptor subfamily 4 group A member 2 / P43354*ENSMUSG0000002682655
Nr4a1 / P12813 / nuclear receptor subfamily 4, group A, member 1 / P22736*ENSMUSG0000002303447
Nr3c2 / nuclear receptor subfamily 3 group C member 2 / P08235*ENSMUSG0000003161819
Esrrg / P62509 / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA. / P62508* / estrogen related receptor gamma*ENSMUSG0000002661018
Esrra / O08580 / Steroid hormone receptor ERR1 / P11474* / estrogen related receptor alpha*ENSMUSG0000002495518
Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*ENSMUSG0000001976817
Esrrb / Q61539 / Steroid hormone receptor ERR2 / O95718* / estrogen related receptor beta*ENSMUSG0000002125517
Esr2 / O08537 / Estrogen receptor beta / Q92731* / estrogen receptor 2*ENSMUSG0000002105517
Nr3c1 / nuclear receptor subfamily 3, group C, member 1 / P04150*ENSMUSG0000002443116
Pgr / Q00175 / Progesterone receptor / P06401*ENSMUSG0000003187016
Ar / P19091 / Androgen receptor / P10275*ENSMUSG0000004653216


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003070  Orphan nuclear receptor
 IPR003072  Orphan nuclear receptor, NOR1 type
 IPR013088  Zinc finger, NHR/GATA-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IDA
 biological_processGO:0001707 mesoderm formation IMP
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007369 gastrulation IMP
 biological_processGO:0007411 axon guidance IMP
 biological_processGO:0009444 pyruvate oxidation IMP
 biological_processGO:0010613 positive regulation of cardiac muscle hypertrophy IEA
 biological_processGO:0010828 positive regulation of glucose transmembrane transport IEA
 biological_processGO:0021766 hippocampus development IMP
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0030534 adult behavior IMP
 biological_processGO:0031100 animal organ regeneration IEA
 biological_processGO:0032765 positive regulation of mast cell cytokine production IMP
 biological_processGO:0035726 common myeloid progenitor cell proliferation IMP
 biological_processGO:0038097 positive regulation of mast cell activation by Fc-epsilon receptor signaling pathway IMP
 biological_processGO:0042472 inner ear morphogenesis IMP
 biological_processGO:0042542 response to hydrogen peroxide IMP
 biological_processGO:0043066 negative regulation of apoptotic process IMP
 biological_processGO:0043303 mast cell degranulation IMP
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043434 response to peptide hormone IEA
 biological_processGO:0043524 negative regulation of neuron apoptotic process IMP
 biological_processGO:0044320 cellular response to leptin stimulus IDA
 biological_processGO:0045333 cellular respiration IMP
 biological_processGO:0045444 fat cell differentiation IDA
 biological_processGO:0045787 positive regulation of cell cycle IMP
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IDA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0046321 positive regulation of fatty acid oxidation IMP
 biological_processGO:0048660 regulation of smooth muscle cell proliferation IEA
 biological_processGO:0048661 positive regulation of smooth muscle cell proliferation IMP
 biological_processGO:0048752 semicircular canal morphogenesis IMP
 biological_processGO:0050679 positive regulation of epithelial cell proliferation IMP
 biological_processGO:0050885 neuromuscular process controlling balance IMP
 biological_processGO:0060005 vestibular reflex IMP
 biological_processGO:0061469 regulation of type B pancreatic cell proliferation IEA
 biological_processGO:0071376 cellular response to corticotropin-releasing hormone stimulus IDA
 biological_processGO:0071870 cellular response to catecholamine stimulus IDA
 biological_processGO:0097009 energy homeostasis IMP
 biological_processGO:1900625 positive regulation of monocyte aggregation IMP
 biological_processGO:1903204 negative regulation of oxidative stress-induced neuron death IGI
 biological_processGO:1903208 negative regulation of hydrogen peroxide-induced neuron death IMP
 biological_processGO:2000108 positive regulation of leukocyte apoptotic process IMP
 biological_processGO:2000253 positive regulation of feeding behavior IMP
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005667 transcription factor complex IDA
 cellular_componentGO:0042629 mast cell granule IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IDA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001223 transcription coactivator binding IPI
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019901 protein kinase binding IEA
 molecular_functionGO:0035035 histone acetyltransferase binding IPI
 molecular_functionGO:0035259 glucocorticoid receptor binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000046 abnormal sulcus ampullaris morphology "anomaly in the structure of the transverse groove on the membranous amupulla of each semicircular duct, where the nerve enters the ampullary crest" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0000172 abnormal bone marrow cell number "Increased or decreased number of cells that make up the core cavities of bones when compared to the norm" [MGI:tc]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000218 increased WBC count "greater than normal WBC numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000219 increased neutrophil count "greater than normal neutrophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000322 increased granulocyte number "greater than expected number of leukocytes that have abundant granules in the cytoplasm: basophils, neutrophils, or eosinophils" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000420 ruffled hair "fuzzy, irregular appearance of the hair" [J:50844]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000599 enlarged liver "larger than average size of the liver" [J:65146]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000689 abnormal spleen morphology "atypical structure of the organ that functions to filter blood and to store red corpuscles and platelets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:27463]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000691 enlarged spleen "increased spleen size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000702 enlarged lymph nodes "lymph nodes of increased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000703 abnormal thymus morphology "anomalous structure or development of the primary lymphoid organ; required for immune system development" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55400]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0000808 abnormal hippocampus development "improper differentiation of the hippocampus" [tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001395 bi-directional circling "circling behavior exhibited in both clockwise and counterclockwise directions" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001399 hyperactivity "general restlessness or excessive movement; more frequent movement from one place to another" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409, J:57125]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001505 hunched posture "stooped low with the limbs pulled in close to the body and arched back" [J:67231, J:30404]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001525 impaired balance "reduced ability of an animal to maintain equilibrium" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:64962, J:17123]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0001577 anemia "less than normal levels of red blood cells, hemoglobin or volume of packed red blood cells " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:53370]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001601 abnormal myelopoiesis "atypical process of bone marrow cell formation and/or bone marrow-derived blood cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:tc]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0001695 abnormal gastrulation "anomalous development and invagination of the embryonic germ layers" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: X/Srydl1Rlb,Tg(Sry)2Ei/0
Genetic Background: involves: 129S6/SvEv * C3H * C57BL/6JEi * MF1

 MP:0002026 leukemia "progressive proliferation of abnormal leukocytes in hematopoietic tissues, organs and blood" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:18542]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0002085 abnormal embryonic tissue morphology "structural abnormality or development of any embryonic tissue resulting in morphological abnormality" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: X/Srydl1Rlb,Tg(Sry)2Ei/0
Genetic Background: involves: 129S6/SvEv * C3H * C57BL/6JEi * MF1

Allelic Composition: Nr4a3tm1Wnt/Nr4a3+
Genetic Background: involves: 129S4/SvJae

 MP:0002174 abnormal gastrulation movements "failure of embryonic cells to migrate, or migrate to the appropriate target during the development and invagination of the primary germ layers" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:52418]
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Allelic Composition: X/Srydl1Rlb,Tg(Sry)2Ei/0
Genetic Background: involves: 129S6/SvEv * C3H * C57BL/6JEi * MF1

 MP:0002428 abnormal semicircular canal "anomaly of the organ of balance composed of three long bony tubes of the labyrinth" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0002906 susceptibility to pharmacologically induced seizures "inability to withstand doses of pharmacological drugs that induce seizure activity in normal animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:69504]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0002961 abnormal axon guidance "defect in the signaling mechanisms that allow precise navigation and connections of axonal growth cones to effector tissues " [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003203 increased neuron apoptosis "increase in the number of neurons undergoing programmed cell death" [RGD:Rat Genome Database submission]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003240 loss of hippocampal neurons "loss of neurons in the hippocampal region of the brain, commonly due to an apoptotic event" [RGD:Rat Genome Database submission]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003651 abnormal axon outgrowth "defect/abnormality in the ability of an axon to extend from a neuron cell body" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator, J:96121]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0003984 embryonic growth retardation "slow or limited development before birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Nr4a3tm1Wnt/Nr4a3+
Genetic Background: involves: 129S4/SvJae

 MP:0003997 tonic-clonic seizures "increased number or decreased threshold for the induction of a seizure characterized by initial rigidity followed by rhythmic jerking movements" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0004742 abnormal vestibular system physiology "any functional anomaly of the sensory system responsible for the sense of head position and movement of the body through space; such anomalies may include impaired balance, dizziness, poor regulation of postural muscle tone and inability to detect quick movements of the head " [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0004809 increased hematopoietic stem cell number "greater cell count of the multipotent, self-renewing stem cells found in the bone marrow and the fetal liver; these give rise to all the types of both the myeloid and lymphoid cell lineages" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005011 increased eosinophil count "greater than normal eosinophil numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005016 decreased lymphocyte number "fewer than normal white blood cell numbers " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0005460 abnormal leukopoiesis "anomalous process of generating white blood cells (leukocytes) from the pluripotent hematopoietic stem cells of the bone marrow; two significant pathways generate various types of leukocytes: myelopoiesis, in which leukocytes in the blood are derived from myeloid stem cells, and lymphopoiesis, in which leukocytes of the lymphatic system (lymphocytes) are generated from lymphoid stem cells" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0006011 abnormal endolymphatic duct morphology "any structural alteration in the small membranous canal, connecting with both saccule and utricle of the membranous labyrinth, passing through the aqueduct of vestibule, and terminating in the endolymphatic sac." [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0006410 abnormal common myeloid progenitor cell morphology "anomaly in the structure of the hematopoietic stem cells that are capable of forming any of the myeloid lineage cells (erythrocytes, granulocytes, thrombocytes, monocytes, and mast cells) but not cells of the lymphoid lineage" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0008235 increased susceptibility to neuronal excitotoxicity "greater than normal amount of neuronal cell death following exposure to a neurotoxic compound, such as kaniate-induced neuronal cell death mediated via a glutamate excitotoxic process" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Sox10tm7.1(Sox10)Weg/Sox10tm7.1(Sox10)Weg,Tg(Dhh-cre)1Mejr/0
Genetic Background: involves: 129P2/OlaHsd * C57BL/6 * FVB/N * SJL

 MP:0008284 abnormal hippocampus pyramidal cell layer 
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0009971 decreased hippocampus pyramidal cell number "decreased number of the projection neurons in the pyramidal layer of the hippocampus" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Daxxtm1Led/Daxxtm1Led
Genetic Background: involves: 129S6/SvEvTac * Black Swiss

 MP:0011085 complete postnatal lethality "premature death anytime between the neonatal period and weaning age of all organisms of a given genotype in a population (Mus: P1 to approximately 3 weeks of age)" [MGI:csmith]
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Allelic Composition: Plin1tm1Asg/Plin1tm1Asg,Tg(Fabp4-Plin*)1Asg/0
Genetic Background: involves: 129S6/SvEvTac * C57BL/6

 MP:0011097 complete embryonic lethality before turning of embryo "death of all organisms of a given genotype in a population between somite formation and the initiation of embryo turning (Mus: E8 to less than E9)" [MGI:csmith]
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Allelic Composition: X/Srydl1Rlb,Tg(Sry)2Ei/0
Genetic Background: involves: 129S6/SvEv * C3H * C57BL/6JEi * MF1

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: Nr4a3tm1Wnt/Nr4a3+
Genetic Background: involves: 129S4/SvJae

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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