ENSMUSG00000046532


Mus musculus

Features
Gene ID: ENSMUSG00000046532
  
Biological name :Ar
  
Synonyms : Androgen receptor / Ar / P19091
  
Possible biological names infered from orthology : P10275
  
Species: Mus musculus
  
Chr. number: X
Strand: 1
Band: C3
Gene start: 98148769
Gene end: 98323215
  
Corresponding Affymetrix probe sets: 10600901 (MoGene1.0st)   1422982_at (Mouse Genome 430 2.0 Array)   1437064_at (Mouse Genome 430 2.0 Array)   1455647_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000052648
NCBI entrez gene - 11835     See in Manteia.
MGI - MGI:88064
RefSeq - NM_013476
RefSeq Peptide - NP_038504
swissprot - P19091
Ensembl - ENSMUSG00000046532
  

This gene has been taged as a transcription factor by TFT
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arENSDARG00000067976Danio rerio
 ARENSGALG00000030879Gallus gallus
 ARENSG00000169083Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Pgr / Q00175 / Progesterone receptor / P06401*ENSMUSG0000003187029
Nr3c2 / nuclear receptor subfamily 3 group C member 2 / P08235*ENSMUSG0000003161828
Nr3c1 / nuclear receptor subfamily 3, group C, member 1 / P04150*ENSMUSG0000002443127
Esr2 / O08537 / Estrogen receptor beta / Q92731* / estrogen receptor 2*ENSMUSG0000002105513
Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*ENSMUSG0000001976813
Esrrg / P62509 / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA. / P62508* / estrogen related receptor gamma*ENSMUSG0000002661012
Esrrb / Q61539 / Steroid hormone receptor ERR2 / O95718* / estrogen related receptor beta*ENSMUSG0000002125512
Esrra / O08580 / Steroid hormone receptor ERR1 / P11474* / estrogen related receptor alpha*ENSMUSG0000002495511
Nr4a2 / Q06219 / Nuclear receptor subfamily 4 group A member 2 / P43354*ENSMUSG0000002682611
Nr4a3 / Q9QZB6 / Nuclear receptor subfamily 4 group A member 3 / Q92570*ENSMUSG0000002834111
Nr4a1 / P12813 / nuclear receptor subfamily 4, group A, member 1 / P22736*ENSMUSG0000002303411


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001103  Androgen receptor
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR035500  Nuclear hormone receptor-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0003073 regulation of systemic arterial blood pressure IGI
 biological_processGO:0003382 epithelial cell morphogenesis IGI
 biological_processGO:0006351 transcription, DNA-templated ISO
 biological_processGO:0006355 regulation of transcription, DNA-templated IDA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IMP
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007283 spermatogenesis IMP
 biological_processGO:0007338 single fertilization IGI
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008584 male gonad development IMP
 biological_processGO:0009566 fertilization IMP
 biological_processGO:0009987 cellular process IDA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0019102 male somatic sex determination IMP
 biological_processGO:0030521 androgen receptor signaling pathway ISO
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IMP
 biological_processGO:0033327 Leydig cell differentiation IMP
 biological_processGO:0035264 multicellular organism growth IGI
 biological_processGO:0042327 positive regulation of phosphorylation IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IMP
 biological_processGO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IMP
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0045720 negative regulation of integrin biosynthetic process IEA
 biological_processGO:0045726 positive regulation of integrin biosynthetic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IEA
 biological_processGO:0048608 reproductive structure development IMP
 biological_processGO:0048638 regulation of developmental growth IMP
 biological_processGO:0048645 animal organ formation IMP
 biological_processGO:0048808 male genitalia morphogenesis IMP
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IMP
 biological_processGO:0050790 regulation of catalytic activity IMP
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0060520 activation of prostate induction by androgen receptor signaling pathway IMP
 biological_processGO:0060571 morphogenesis of an epithelial fold IMP
 biological_processGO:0060599 lateral sprouting involved in mammary gland duct morphogenesis IMP
 biological_processGO:0060685 regulation of prostatic bud formation IGI
 biological_processGO:0060736 prostate gland growth IMP
 biological_processGO:0060740 prostate gland epithelium morphogenesis IMP
 biological_processGO:0060742 epithelial cell differentiation involved in prostate gland development IMP
 biological_processGO:0060748 tertiary branching involved in mammary gland duct morphogenesis IMP
 biological_processGO:0060749 mammary gland alveolus development IMP
 biological_processGO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development IDA
 biological_processGO:0061458 reproductive system development IGI
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 biological_processGO:0071394 cellular response to testosterone stimulus IDA
 biological_processGO:0072520 seminiferous tubule development IMP
 biological_processGO:1903076 regulation of protein localization to plasma membrane IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005886 plasma membrane IDA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity ISO
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0004882 androgen receptor activity ISO
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0005497 androgen binding IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0008289 lipid binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:0070974 POU domain binding IDA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
Ub-specific processing proteases
RUNX2 regulates osteoblast differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000005 increased brown fat amount "increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208]
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Allelic Composition: Ank1ity16/Ank1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * DBA/2J

 MP:0000008 increased white fat amount "increased quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Prkntm1Shn/Prkntm1Shn
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000130 abnormal cancellous bone morphology "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000133 abnormal long bone metaphysis morphology "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000172 abnormal bone marrow cell number "Increased or decreased number of cells that make up the core cavities of bones when compared to the norm" [MGI:tc]
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Allelic Composition: Pax6tm1Gfs/Pax6+
Genetic Background: involves: 129S7/SvEvBrd

 MP:0000242 impaired fertilization "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0000245 abnormal erythropoiesis "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator]
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Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

 MP:0000278 abnormal myocardial fiber morphology "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0000372 irregular coat pigmentation "uneven coloration of the hair" [J:65030]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000440 domed skull 
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000539 distended urinary bladder "stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000562 polydactyly "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000564 syndactyly "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000627 abnormal mammary gland morphology "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183]
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000661 small ventral prostate "reduced size of lateral lobe of the prostate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

 MP:0000662 abnormal branching of the mammary ductal tree "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000664 small coagulating gland "reduced size of the coagulating gland" [J:64981]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

 MP:0000709 enlarged thymus "increased size of thymus" [J:50053]
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0000747 muscle weakness "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm4(AR)Dmr/Ar+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000748 progressive muscle weakness "increasing loss of strength over time" [MGI:CLS, J:67994]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000751 myopathy "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000914 exencephaly "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0000938 motor neuron degeneration "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000955 abnormal spinal cord morphology "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0000968 abnormal sensory neuron innervation "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

 MP:0001119 abnormal female reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

 MP:0001144 fused vaginal opening "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

 MP:0001145 abnormal male reproductive anatomy "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

 MP:0001146 abnormal testis morphology "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001147 small testis "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: ArTfm-Jms/Y
Genetic Background: C57BL/6JJms

Allelic Composition: Arem1Liuy/Y
Genetic Background: involves: C57BL/6J * CBA

 MP:0001148 enlarged testes "increased size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001152 Leydig cell hyperplasia "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065]
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0001153 small seminiferous tubules "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm3.1(AR)Ska/Y
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0001154 seminiferous tubule degeneration "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001155 arrest of spermatogenesis "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

 MP:0001156 abnormal spermatogenesis "incomplete maturation or aberrant formation of the male gametes" [J:58959]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

 MP:0001157 small seminal gland "reduced size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-icre)AJako/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0001158 abnormal prostate morphology "mallformed gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2

 MP:0001159 absent prostate gland "missing gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66126]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0001163 abnormal coagulating gland "malformed or malfunctioning anterior lobe of the prostate" [J:64981]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

 MP:0001168 prostate epithelial dysplasia "abnormal development of the prostate epithelium" [J:63764]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2

 MP:0001259 abnormal body weight "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator]
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Allelic Composition: Prkntm1Shn/Prkntm1Shn
Genetic Background: involves: 129S4/SvJae

 MP:0001260 increased body weight "greater than normal average weight " [J:33400]
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Allelic Composition: Disp1tm1Ptch/Disp1tm1Ptch
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * Swiss Webster)

Allelic Composition: Artm1(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: ArTfm-Jms/ArTfm-Jms
Genetic Background: C57BL/6JJms

 MP:0001261 obese "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Prkntm1Shn/Prkntm1Shn
Genetic Background: involves: 129S4/SvJae

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001265 reduced body size "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0001382 abnormal nursing "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001552 increased circulating triglyceride level "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001559 hyperglycemia "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0001731 abnormal postnatal growth "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0001732 postnatal growth retardation "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0001750 increased circulating follicle stimulating hormone level "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0001751 increased circulating luteinizing hormone level "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0001764 abnormal homeostasis "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0001875 testis inflammation "local accumulation of fluid, plasma proteins, and leukocytes in the testis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001882 abnormal lactation "atypical production of milk from the mammary gland" [J:51296]
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0001919 abnormal reproductive system physiology "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Prkntm1Shn/Prkntm1Shn
Genetic Background: involves: 129S4/SvJae

 MP:0001921 reduced fertility "diminished ability to produce live offspring" [J:65030]
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Allelic Composition: Braftm1Bbd/Braf+
Genetic Background: B6.129-Braftm1Bbd

Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0001922 reduced male fertility "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0001925 male infertility "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409]
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Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001926 female infertility "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193]
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Allelic Composition: ArTfm-Jms/ArTfm-Jms
Genetic Background: C57BL/6JJms

 MP:0001929 abnormal gametogenesis "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324]
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Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: C57BL/6

 MP:0001930 abnormal meiosis "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr
Genetic Background: involves: 129/Sv * C57BL/6

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0001935 reduced litter size "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Pax6132-14Neu/Pax6132-14Neu
Genetic Background: C3.Cg-Pax6132-14Neu

Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0001939 secondary sex reversal "secondary sexual phenotype is not consistent with the chromosomal sex, i.e., internal and/or external genitalia are inconsistent with chromosomal sex " [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm-Jms/Y
Genetic Background: C57BL/6JJms

Allelic Composition: Arem1Liuy/Y
Genetic Background: involves: C57BL/6J * CBA

 MP:0001940 testicular hypoplasia "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002009 preneoplasia "state preceding the pathological process resulting in a neoplasm; does not necessarily imply cancerous development" [J:47225]
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Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

Allelic Composition: Artm1.1Chc/Artm1.1Chc
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0002052 decreased tumor incidence "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Artm2(AR)Dmr/Y,Tg(TRAMP)8247Ng/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002059 abnormal seminal gland morphology "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-icre)AJako/0
Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL

 MP:0002075 abnormal coat color "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Irs1tm2.1Mfw/Irs1tm2.1Mfw,Irs2tm2Mfw/Irs2tm2Mfw,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA * FVB/N

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002079 increased circulating insulin level "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1Jdz/Y
Genetic Background: B6.129X1-Artm1Jdz

Allelic Composition: Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

Allelic Composition: Artm1Rax/Artm1Rax
Genetic Background: involves: 129S/SvEv * C57BL/6J

Allelic Composition: Artm1Rax/Y
Genetic Background: involves: 129S/SvEv * C57BL/6J

 MP:0002188 small heart "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0002209 germ cell depletion "reduced numbers of any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Pax6132-14Neu/Pax6132-14Neu
Genetic Background: C3.Cg-Pax6132-14Neu

 MP:0002212 abnormal secondary sex determination "gonadal development may or may not be normal, and the phenotype of the animal outside the gonad does not match chromosomal sex or is ambiguous" [llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Tfamtm1Lrsn/Tfamtm1Lrsn
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: ArTfm-Jms/Y
Genetic Background: C57BL/6JJms

 MP:0002216 abnormal seminiferous tubule morphology "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0002286 cryptorchism "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0002557 abnormal social/conspecific interaction "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator]
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Allelic Composition: Fshrtm1Saco/Fshrtm1Saco
Genetic Background: involves: C57BL/6

 MP:0002631 abnormal epididymis morphology "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002660 abnormal caput "anomalous structure of the head of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0002661 abnormal corpus "anomalous structure of the body of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0002662 abnormal cauda "anomalous structure of the tail of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0002669 abnormal scrotum morphology "malformation of the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002670 absent scrotum "missing the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0002673 abnormal sperm count "increased or decreased numbers of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0002687 oligozoospermia "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312]
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Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0002774 small prostate "reduced size of the gland in males that secretes part of the seminiferous fluid" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0
Genetic Background: Not Specified

Allelic Composition: Artm3.1(AR)Ska/Y
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0002780 decreased circulating testosterone level "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0002781 increased circulating testosterone level "greater than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm4(AR)Dmr/Ar+
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm3.1(AR)Ska/Y
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0002784 abnormal Sertoli cell morphology "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0002786 abnormal Leydig cell morphology "malformation or absence of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

 MP:0002789 male pseudohermaphroditism "pseudohermaphroditism in which the gonads are male (testes) and the karyotype is XY but the secondary sex characteristics are female-like or ambiguous" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1.1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J

Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

 MP:0002790 decreased circulating follicle stimulating hormone level "less than expected blood concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0002834 decreased heart weight "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0003084 abnormal skeletal muscle fiber morphology "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0003124 hypospadia "a urethral opening located closer to the base of the penis and not at the tip" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003157 impaired muscle relaxation "reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0003205 testicular atrophy "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003448 altered tumor morphology "changes in the expected pathology for a given tumor type compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
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Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0003534 blind vagina "presence the female reproductive canal that ends in a sac and does not connect to internal genitalia" [ncbi:Matthew Mailman, NCBI request, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0003550 short perineum "reduced length of the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

 MP:0003553 abnormal foreskin morphology "anomaly of the loose fold of skin that covers the penis" [ncbi:Matthew Mailman, NCBI request]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0003557 absent vas deferens "absence of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0003607 abnormal prostate physiology "malfunction of the gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0003642 absent seminal gland "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0003698 abnormal male reproductive system physiology "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003721 increased tumor growth/size "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0003921 abnormal left ventricle morphology "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0003936 abnormal reproductive system development "developmental anomaly of any of the organs involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA

 MP:0004145 abnormal muscle electrophysiology "anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0004502 decreased incidence of chemically-induced tumors "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

Allelic Composition: Artm1.1Chc/Artm1.1Chc
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0004543 abnormal sperm physiology "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0004565 small myocardial fiber "decreased size of the cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0004727 absent epididymis "absence of the elongated structure connected to the posterior surface of the testis, consisting of the head, body, and tail, which turns sharply on itself to become the ductus deferens (vas deferens)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y
Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)

Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1.1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N

 MP:0004851 increased testis weight "greater average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0004852 decreased testis weight "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: involves: 129X1/SvJ * C57BL/6

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0
Genetic Background: involves: 129X1/SvJ * BALB/cJ

 MP:0004856 decreased ovary weight "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004893 decreased adiponectin level "reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004901 decreased male germ cell number "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

 MP:0004905 decreased uterus weight "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0004910 decreased seminal gland weight "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0004929 decreased epididymis weight "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl

 MP:0004933 abnormal epididymis epithelium morphology "any structural anomaly of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004934 epididymis epithelium degeneration "pathological deterioration of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0004958 enlarged prostate "increased size of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2

 MP:0004961 increased prostate weight "greater than average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0004962 decreased prostate weight "reduction in the average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl

Allelic Composition: Artm3.1(AR)Ska/Y
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0004984 increased osteoclast cell number "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005117 increased circulating pituitary hormone level "greater than expected concentraton of any of the pituitary hormones in the blood" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Artm1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

 MP:0005149 abnormal gubernaculum morphology "dysmorphology of the genitoinguinal ligaments that, in the male, connect the fetal testis to the developing scrotum, and, in the female, connect the ovaries to the uterus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55881]
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad
Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa

 MP:0005159 azoospermia "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

 MP:0005187 abnormal penis morphology "anomalous structure of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0005188 small penis "in comparison to the norm, reduced size of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005189 abnormal anogenital distance "in comparison to the norm, aberration in the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005250 Sertoli cell hypoplasia "decreased number of cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:70212]
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Allelic Composition: Artm1Fcl/Y
Genetic Background: involves: 129S2/SvPas * C57BL/6

 MP:0005293 impaired glucose tolerance "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005317 increased triglyceride level "higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005331 insulin resistance "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005452 abnormal body fat amount "more or less than the normal total amount of connective tissue composed of fat cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0005455 increased weight gain "greater increase in body weight over existing weight when compared to the average increase in weight on the same diet, with equal energy (calorie) intake " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:42702]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005458 increased percent body fat "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Disp1tm1Ptch/Disp1tm1Ptch
Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * Swiss Webster)

Allelic Composition: Artm1(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0005536 Leydig cell hypoplasia "reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0005553 increased circulating creatinine level "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0005559 increased circulating glucose level "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0005565 increased blood urea nitrogen level "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0005598 decreased ventricle muscle contractility "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0005608 cardiac interstitial fibrosis "formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0005627 increased circulating potassium level "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0005669 increased circulating leptin level "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006262 testis tumor "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:60034]
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0006308 enlarged seminiferous tubules "increased diameter of the tubules in the testes where spermatogenesis occurs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0006369 supernumerary incisors "more than a pair, top and/or bottom, of the long pointed teeth that are the most anterior and prominent in the jaw" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0006378 abnormal spermatogonia morphology "anomaly in the number, structure or development of the large unspecialized male germ cells that give rise to spermatocytes" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006379 abnormal spermatocyte morphology "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0006380 abnormal spermatid morphology "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0006420 abnormal peritubular myoid cell morphology "any structural anomaly of the flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0008214 increased immature B cell number "greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

 MP:0008250 abnormal myeloid leukocyte morphology "any structural anomaly of a cell of the monocyte, granulocyte, or mast cell lineage" [CL:0000766]
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Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

 MP:0008261 arrest of male meiosis "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: ArTfm/Y
Genetic Background: involves: STOCK EdaTa Atp7aMo-blo

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1.1Reb/Y
Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J

Allelic Composition: Artm1.1Jdz/Y
Genetic Background: B6.129X1-Artm1.1Jdz

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL

Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

Allelic Composition: ArTfm/Y
Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo

 MP:0008280 male germ cell apoptosis "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0008892 abnormal sperm flagellum "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0009066 decreased oviduct weight "reduction in the average weight of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009073 absent Wolffian ducts "absence of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and later develop into the ductus deferens in the male" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1.1Verh/Y
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6

 MP:0009115 abnormal fat cell morphology "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009198 abnormal male genitalia morphology "any structural anomaly of the masculine organs of reproduction or generation, external or internal" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0009199 abnormal external male genitalia morphology "any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm2Ska/Y,Gli1tm3(cre/ERT2)Alj/Gli1+
Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA

 MP:0009204 absent external male genitalia "absence of the external masculine genital organs, including the penis and scrotum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009220 prostate adenocarcinoma "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Ptentm1Hwu/Ptentm1Hwu,Tg(Pbsn-cre)4Prb/0
Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2

 MP:0009237 kinked sperm flagellum "a sharp bend or zigzag in the sperm tail" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0009238 coiled sperm flagellum "abnormal twisting of the sperm flagellum into coils or spirals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0009243 hairpin sperm flagellum "a structural alteration where the sperm flagellum becomes bent back (folded) on itself to form a hairpin (loop) structure; a sharp hairpin-like bend formation can disrupt the axial structures and cause the sperm tail to become kinked" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0009283 decreased gonadal fat pad weight "less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009285 increased gonadal fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009294 increased interscapular fat pad weight 
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009298 increased mesenteric fat pad weight 
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0009302 increased renal fat pad weight 
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009355 increased liver triglyceride level "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0009403 increased variability of skeletal muscle fiber size "greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009404 centrally nucleated skeletal muscle fibers "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009413 skeletal muscle fiber atrophy "a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009642 abnormal blood homeostasis "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0009659 striated fur "hair or fur characterized by transverse, usually parallel, markings due to an anomaly in hair color, texture, or growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0009697 abnormal copulation "an anomaly in sexual union that normally enables the transfer of ejaculate (sperm) from male to female, sometimes resulting in the fertilization of an egg" [GO:0007620, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0010031 abnormal cranium size "deviation from the average range of cranium size compared to normal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010045 increased omental fat pad weight "greater than average weight of the encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"]
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010053 decreased grip strength "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm4(AR)Dmr/Ar+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0010182 decreased susceptibility to weight gain "smaller increase in body weight over time when compared to the average increase in weight on the same diet, with equal energy (calorie) intake" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6

 MP:0010231 transverse fur striping "presence of stripes of pigmented hair, usually black, of variable degree and location in the coat" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0010308 decreased tumor latency "earlier onset of tumor occurrence than expected" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0010357 increased prostate gland tumor incidence "greater than the expected number of neoplams in the prostate gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Artm1(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

Allelic Composition: Artm2(AR)Dmr/Y,Tg(TRAMP)8247Ng/0
Genetic Background: involves: 129S1/Sv * C57BL/6

Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0
Genetic Background: involves: C57BL/6 * C57BL/6J * CBA

 MP:0011088 partial neonatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
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Allelic Composition: ArTfm EdaTa-25H/Y
Genetic Background: involves: 101/H * C3H/HeH

Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+
Genetic Background: involves: 101/H * C3H/HeH

 MP:0011532 decreased urine major urinary protein level "reduced amount in the urine of a family of alpha2-microglobulin-related liver secretory proteins that comprise a major protein component of mouse urine" [MGI:csmith]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0011533 increased urine major urinary protein level "increased amount in the urine of a family of alpha2-microglobulin-related liver secretory proteins that comprise a major protein component of mouse urine" [MGI:csmith]
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Allelic Composition: Artm4(AR)Dmr/Ar+
Genetic Background: involves: 129S1/Sv * C57BL/6J

 MP:0013598 Leydig cell hypertrophy "increased size of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH)" [MGI:Anna]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2

Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0
Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL

 MP:0013600 testis degeneration "a retrogressive impairment of function or destruction of either or both of the male reproductive glands" [MGI:Anna]
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/?
Genetic Background: involves: C57BL/6 * CBA

 MP:0013604 abnormal adult Leydig cell differentiation "atypical formation of or inability to produce the second or adult population of Leydig cells (ALCs) between birth and puberty; ALCs arise in the interstitium of adult testes from unknown progenitor cells and become the major source of androgens that control differentiation of the male reproductive tract and spermatogenesis; ALCs are not derived from fetal Leydig cells (FLCs), and the origin and the molecular events that control ALC differentiation are poorly understood" [PMID:23568777]
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Allelic Composition: ArTfm/Y
Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +

 MP:0013899 abnormal seminal vesicle epithelium morphology "any structural anomaly of the pseudostratified columnar epithelium that lines the seminal vesicles and consists of tall, non-ciliated columnar cells and short, rounded basal cells that rest on the basal lamina; polarized columnar cells show features typical of secretory epithelium, including a well-developed Golgi complex, abundant rough endoplasmic reticulum, numerous mitochondria, and apical secretory vesicles; basal cells are the stem cells from which the columnar cells are derived" [ISBN:0781767903, ISBN:1455703079, MGI:Anna]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl

Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0013904 abnormal seminal vesicle muscle layer morphology "any structural anomaly of the thick muscular layer of the seminal vesicle consisting of an inner circular and outer longitudinal layer of smooth muscle which contracts during the emission phase of ejaculation to expel seminal vesicle fluid into the prostatic urethra" [MGI:Anna]
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/?
Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl

 MP:0020039 increased bone ossification "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597]
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0
Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N

 MP:0020355 abnormal Sertoli cell barrier morphology "any structural anomaly of the physical barrier found between adjacent Sertoli cells within the seminiferous tubules; the sertoli cell barrier consists of several types of cellular junctions including tight junctions, gap junctions and adhesion junctions, and divides the seminiferous tubules into the basal and apical (adluminal) compartments" [PMID:24713828 http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=572;epage=580;aulast=Jiang]
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Allelic Composition: Gt(ROSA)26Sortm4(CAG-EGFP*)Nat/Gt(ROSA)26Sortm4(CAG-EGFP*)Nat
Genetic Background: involves: 129 * C57BL/6

 MP:0020356 abnormal Sertoli cell barrier function "any functional anomaly of the physical barrier found between the blood vessels and the seminiferous tubules of the testes; this barrier between Sertoli cells is composed of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions" [https://en.wikipedia.org/wiki/Blood%E2%80%93testis_barrier, PMID:24713828 http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=572;epage=580;aulast=Jiang, PMID:24803656]
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Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/?
Genetic Background: involves: 129S4/SvJaeSor * FVB/N

Allelic Composition: Artm2.1Reb/Ar+,Tg(Amh-cre)8815Reb/?
Genetic Background: 129S(FVB)-Artm2.1Reb

 MP:0020378 abnormal cell cytoskeleton morphology "any anomaly in the structure of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm" [GO:0005856, MGI:mberry]
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Allelic Composition: Artm4(AR)Dmr/Y
Genetic Background: involves: 129S1/Sv * C57BL/6J

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000005886 Ncoa2 / Q61026 / Nuclear receptor coactivator 2 / Q15596*  / complex / reaction
 ENSMUSG00000023944 P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*  / complex
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / complex
 ENSMUSG00000030357 Fkbp4 / P30416 / Peptidyl-prolyl cis-trans isomerase FKBP4 Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed / Q02790* / FK506 binding protein 4*  / complex
 ENSMUSG00000071072 Ptges3 / Q9R0Q7 / Prostaglandin E synthase 3 / Q15185*  / complex
 ENSMUSG00000057672 Pkn1 / P70268 / Serine/threonine-protein kinase N1 / Q16512* / protein kinase N1*  / complex / reaction
 ENSMUSG00000039153 Runx2 / Q08775 / runt related transcription factor 2 / Q13950*  / complex / reaction
 ENSMUSG00000099517 P68433 / Hist1h3g / Histone H3.1   / complex / reaction
 ENSMUSG00000028397 Kdm4c / Q8VCD7 / Mus musculus lysine (K)-specific demethylase 4C (Kdm4c), transcript variant 3, mRNA. / Q9H3R0* / lysine demethylase 4C*  / reaction / complex
 ENSMUSG00000060981 P62806 / Hist1h4h / Histone H4   / complex / reaction
 ENSMUSG00000026021 Sumo1 / P63166 / Small ubiquitin-related modifier 1 / P63165* / small ubiquitin-like modifier 1*  / reaction / complex
 ENSMUSG00000029640 Usp12 / Q9D9M2 / ubiquitin specific peptidase 12 / O75317*  / complex
 ENSMUSG00000100210 P84228 / Hist1h3f / Histone H3.2   / reaction / complex
 ENSMUSG00000060743 H3f3a / P84244 / Histone H3.3 / P84243* / H3 histone family member 3A*  / reaction / complex
 ENSMUSG00000036940 Kdm1a / Q6ZQ88 / Mus musculus lysine (K)-specific demethylase 1A (Kdm1a), transcript variant 3, mRNA. / O60341* / lysine demethylase 1A*  / complex / reaction
 ENSMUSG00000015120 Ube2i / P63280 / ubiquitin-conjugating enzyme E2I / P63279*  / reaction
 ENSMUSG00000032512 Wdr48 / Q8BH57 / WD repeat domain 48 / Q8TAF3*  / complex
 ENSMUSG00000055780 Usp26 / Q99MX1 / ubiquitin specific peptidase 26 / Q9BXU7*  / complex






 

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