MP:0000005 | increased brown fat amount | "increased amount of thermogenic tissue in the body that is composed of cells containing multiple small fat droplets" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:14208] |
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Allelic Composition: Ank1ity16/Ank1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * DBA/2J
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MP:0000008 | increased white fat amount | "increased quantity of fat-storing cells/tissue" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Prkntm1Shn/Prkntm1Shn Genetic Background: involves: 129S4/SvJae
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000130 | abnormal cancellous bone morphology | "structural anomaly of bone that has a latticelike or spongy structure" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000133 | abnormal long bone metaphysis morphology | "malformed conical section of bone between the epiphysis and diaphysis of the long bones" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:61295] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000172 | abnormal bone marrow cell number | "Increased or decreased number of cells that make up the core cavities of bones when compared to the norm" [MGI:tc] |
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Allelic Composition: Pax6tm1Gfs/Pax6+ Genetic Background: involves: 129S7/SvEvBrd
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MP:0000242 | impaired fertilization | "defect or reduced ability in the process beginning with penetration of the secondary oocyte by the spermatozoon and completed by fusion of the male and female pronucei" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0000245 | abnormal erythropoiesis | "atypical process of red blood cell formation" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, tc:Teresa Chu , Mouse Genome Informatics Curator] |
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Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
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MP:0000278 | abnormal myocardial fiber morphology | "malformed or poorly developed cardiac muscle fibers, the multinucleated muscle cells of the heart" [J:18048] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0000280 | thin ventricular wall | "decreased depth of the cardiac wall of the heart ventricles" [J:45302] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0000372 | irregular coat pigmentation | "uneven coloration of the hair" [J:65030] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0000440 | domed skull | |
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0000539 | distended urinary bladder | "stretched musculomembranous bag for holding urine" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000562 | polydactyly | "greater than 5 digits on one or more autopods" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0000564 | syndactyly | "any degree of webbing or fusion of the digits, may involve only soft tissues or also can include bone" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0000627 | abnormal mammary gland morphology | "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183] |
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000661 | small ventral prostate | "reduced size of lateral lobe of the prostate" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63764] |
Show
Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
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MP:0000662 | abnormal branching of the mammary ductal tree | "anomaly in the development of the channels that secrete milk and direct milk to the nipple" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000664 | small coagulating gland | "reduced size of the coagulating gland" [J:64981] |
Show
Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
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MP:0000709 | enlarged thymus | "increased size of thymus" [J:50053] |
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0000747 | muscle weakness | "loss of muscle strength" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm4(AR)Dmr/Ar+ Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000748 | progressive muscle weakness | "increasing loss of strength over time" [MGI:CLS, J:67994] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000751 | myopathy | "any abnormal condition or disease of the skeletal muscle" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:42574] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000914 | exencephaly | "neurocranial defects resulting in exposure or extrusion of the brain" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:49840] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0000938 | motor neuron degeneration | "retrogressive impairment of function or destruction of the cells that innervate an effector (muscle or glandular) tissue" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000955 | abnormal spinal cord morphology | "malformation or disorganization of the cylindrical tissue of the vertebral canal that extends from the medulla oblongata to the conus medullaris" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0000968 | abnormal sensory neuron innervation | "defective or incomplete supply of nerve fibers to sensory termini or to spinal cord" [J:31622] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
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MP:0001119 | abnormal female reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that bears the offspring" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
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MP:0001144 | fused vaginal opening | "condition in which the external vaginal opening is closed by the adherence of the epithelium of the vagina" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
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MP:0001145 | abnormal male reproductive anatomy | "anomalous structure of the organs associated with producing offspring in the gender that produces spermatozoa" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Tfamtm1Lrsn/Tfamtm1Lrsn Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
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MP:0001146 | abnormal testis morphology | "anomalous structure of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001147 | small testis | "reduced size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:58959] |
Show
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Reb/Y Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: ArTfm-Jms/Y Genetic Background: C57BL/6JJms
Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001148 | enlarged testes | "increased size of the male reproductive glands" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:63229] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001152 | Leydig cell hyperplasia | "increased number of interstitial cells of the seminiferous tubules that secrete testosterone" [J:45065] |
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0001153 | small seminiferous tubules | "reduced diameter of the tubules in the testes where spermatogenesis occurs" [J:50844] |
Show
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm3.1(AR)Ska/Y Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0001154 | seminiferous tubule degeneration | "a retrogressive impairment of function or destruction of the tubules in the testes where spermatogenesis occurs" [J:50844] |
Show
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001155 | arrest of spermatogenesis | "block of the process by which spermatogonial stem cells divide and differentiate into spermatozoa" [J:62271] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
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MP:0001156 | abnormal spermatogenesis | "incomplete maturation or aberrant formation of the male gametes" [J:58959] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
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MP:0001157 | small seminal gland | "reduced size, compared to the norm, of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-icre)AJako/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0001158 | abnormal prostate morphology | "mallformed gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:63764] |
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2
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MP:0001159 | absent prostate gland | "missing gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66126] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0001163 | abnormal coagulating gland | "malformed or malfunctioning anterior lobe of the prostate" [J:64981] |
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
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MP:0001168 | prostate epithelial dysplasia | "abnormal development of the prostate epithelium" [J:63764] |
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2
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MP:0001259 | abnormal body weight | "anomaly in average weight compared to the norm" [cwg:Carroll W. Goldsmith, Mouse Genome Informatics Curator] |
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Allelic Composition: Prkntm1Shn/Prkntm1Shn Genetic Background: involves: 129S4/SvJae
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MP:0001260 | increased body weight | "greater than normal average weight " [J:33400] |
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Allelic Composition: Disp1tm1Ptch/Disp1tm1Ptch Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * Swiss Webster)
Allelic Composition: Artm1(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: ArTfm-Jms/ArTfm-Jms Genetic Background: C57BL/6JJms
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MP:0001261 | obese | "excessively fat; an increase in fat in the subcutaneous connective tissue" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cml:Cathleen M. Lutz , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkntm1Shn/Prkntm1Shn Genetic Background: involves: 129S4/SvJae
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MP:0001262 | decreased body weight | "lower than normal average weight " [J:61295] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0001265 | reduced body size | "smaller than average body weight, height and/or length of an organism compared to controls" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:23170] |
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0001382 | abnormal nursing | "females do not nurse pups or nurse pups infrequently" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0001552 | increased circulating triglyceride level | "higher than normal concentration of triacylglycerols in the blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, J:65416] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001559 | hyperglycemia | "abnormally high concentration of glucose in the blood; generally refers to a pathological state" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0001731 | abnormal postnatal growth | "anomaly in reaching a developmental stage or stages after birth" [il:Ira Lu, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0001732 | postnatal growth retardation | "slow or limited development after birth " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0001750 | increased circulating follicle stimulating hormone level | "higher than normal levels in the blood stream of FSH, the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [J:35782, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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MP:0001751 | increased circulating luteinizing hormone level | "higher than the normal levels in the bloodstream of LH, the hormone that regulates steroid production by the interstitial cells of the testis and the ovary" [J:35782, MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0001764 | abnormal homeostasis | "anomaly in the state of equilibrium in the body with respect to various functions and to chemical composition of the fluids and tissues" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6J
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MP:0001875 | testis inflammation | "local accumulation of fluid, plasma proteins, and leukocytes in the testis" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001882 | abnormal lactation | "atypical production of milk from the mammary gland" [J:51296] |
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Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0001919 | abnormal reproductive system physiology | "anomaly in the function of the organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Prkntm1Shn/Prkntm1Shn Genetic Background: involves: 129S4/SvJae
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MP:0001921 | reduced fertility | "diminished ability to produce live offspring" [J:65030] |
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Allelic Composition: Braftm1Bbd/Braf+ Genetic Background: B6.129-Braftm1Bbd
Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0001922 | reduced male fertility | "reduced ability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:61340] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0001925 | male infertility | "inability of male to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:60409] |
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Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0001926 | female infertility | "inability of female to produce live offspring" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:34193] |
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Allelic Composition: ArTfm-Jms/ArTfm-Jms Genetic Background: C57BL/6JJms
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MP:0001929 | abnormal gametogenesis | "defective formation or differentiation of germ cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:cls, J:42324] |
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Allelic Composition: Fshrtm1Saco/Fshrtm1Saco Genetic Background: involves: C57BL/6
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MP:0001930 | abnormal meiosis | "malfunction in the process of nuclear division that results in gametes with one half the normal number of the original cell" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Hoxa2tm1Fmr/Hoxa2tm1Fmr Genetic Background: involves: 129/Sv * C57BL/6
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0001935 | reduced litter size | "fewer live born pups in a litter compared to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Pax6132-14Neu/Pax6132-14Neu Genetic Background: C3.Cg-Pax6132-14Neu
Allelic Composition: Artm1Chc/Ar+,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0001939 | secondary sex reversal | "secondary sexual phenotype is not consistent with the chromosomal sex, i.e., internal and/or external genitalia are inconsistent with chromosomal sex " [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Reb/Y Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm-Jms/Y Genetic Background: C57BL/6JJms
Allelic Composition: Arem1Liuy/Y Genetic Background: involves: C57BL/6J * CBA
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MP:0001940 | testicular hypoplasia | "decreased cell number in the testicles" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0002009 | preneoplasia | "state preceding the pathological process resulting in a neoplasm; does not necessarily imply cancerous development" [J:47225] |
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Allelic Composition: Hoxa2tm2.1Fmr/Hoxa2tm2.1Fmr Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
Allelic Composition: Artm1.1Chc/Artm1.1Chc Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0002052 | decreased tumor incidence | "less than the expected number of abnormal growths in a specific population" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Artm2(AR)Dmr/Y,Tg(TRAMP)8247Ng/0 Genetic Background: involves: 129S1/Sv * C57BL/6
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MP:0002059 | abnormal seminal gland morphology | "anomalous structure of one of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Esr1tm1.2Mma/Esr1tm1.2Mma,Tg(Cyp17a1-icre)AJako/0 Genetic Background: involves: 129S2/SvPas * C57BL/6 * SJL
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MP:0002075 | abnormal coat color | "irregular or unusual pigmentation pattern of the hair in relation to control animals" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Irs1tm2.1Mfw/Irs1tm2.1Mfw,Irs2tm2Mfw/Irs2tm2Mfw,Speer6-ps1Tg(Alb-cre)21Mgn/Speer6-ps1+ Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6J * DBA * FVB/N
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0002079 | increased circulating insulin level | "greater than normal levels of insulin in blood" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0002083 | premature death | "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Kiss1rtm1Gstn/Kiss1rtm1Gstn Genetic Background: involves: 129P2/OlaHsd
Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0002169 | no phenotype detected | "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1Jdz/Y Genetic Background: B6.129X1-Artm1Jdz
Allelic Composition: Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Artm1Rax/Artm1Rax Genetic Background: involves: 129S/SvEv * C57BL/6J
Allelic Composition: Artm1Rax/Y Genetic Background: involves: 129S/SvEv * C57BL/6J
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MP:0002188 | small heart | "reduced size of the heart relative to average" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, J:67044] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0002209 | germ cell depletion | "reduced numbers of any of the reproductive (generative) cells of a multicellular organism, whether they are undifferentiated or fully differentiated" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Pax6132-14Neu/Pax6132-14Neu Genetic Background: C3.Cg-Pax6132-14Neu
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MP:0002212 | abnormal secondary sex determination | "gonadal development may or may not be normal, and the phenotype of the animal outside the gonad does not match chromosomal sex or is ambiguous" [llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Tfamtm1Lrsn/Tfamtm1Lrsn Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: ArTfm-Jms/Y Genetic Background: C57BL/6JJms
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MP:0002216 | abnormal seminiferous tubule morphology | "malformation of the tubules in the testes where spermatogenesis occurs" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0002286 | cryptorchism | "failure of one or both of the testes to descend into the scrotum around the time of birth" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Reb/Y Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0002557 | abnormal social/conspecific interaction | "deviation of the normal behavior of mice towards each other" [csmith:Cynthia L. Smith, Mouse Genome Informatics Curator] |
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Allelic Composition: Fshrtm1Saco/Fshrtm1Saco Genetic Background: involves: C57BL/6
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MP:0002631 | abnormal epididymis morphology | "malformation of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002660 | abnormal caput | "anomalous structure of the head of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0002661 | abnormal corpus | "anomalous structure of the body of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0002662 | abnormal cauda | "anomalous structure of the tail of the epididymis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0002669 | abnormal scrotum morphology | "malformation of the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0002670 | absent scrotum | "missing the external sac of skin that encloses the testes" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0002673 | abnormal sperm count | "increased or decreased numbers of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0002687 | oligozoospermia | "reduced concentration of spermatozoa " [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, J:57312] |
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Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0002774 | small prostate | "reduced size of the gland in males that secretes part of the seminiferous fluid" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Scxtm1.1Stzr/Scxtm1.1Stzr,Tg(Scx-GFP)1Stzr/0 Genetic Background: Not Specified
Allelic Composition: Artm3.1(AR)Ska/Y Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0002780 | decreased circulating testosterone level | "less than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0002781 | increased circulating testosterone level | "greater than the normal blood concentration of this most potent androgen" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm4(AR)Dmr/Ar+ Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm3.1(AR)Ska/Y Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0002784 | abnormal Sertoli cell morphology | "malformation of the cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [J:65900, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0002786 | abnormal Leydig cell morphology | "malformation or absence of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
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MP:0002789 | male pseudohermaphroditism | "pseudohermaphroditism in which the gonads are male (testes) and the karyotype is XY but the secondary sex characteristics are female-like or ambiguous" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator, llw2:Linda Washburn , Mouse Genome Informatics Curator] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1.1Reb/Y Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
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MP:0002790 | decreased circulating follicle stimulating hormone level | "less than expected blood concentration of the hormone that, in females, stimulates the graafian follicles of the ovary and assists in follicular maturation and the secretion of estradiol; in the male it stimulates the epithelium of the seminiferous tubules and is partly responsible for spermatogenesis " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0002834 | decreased heart weight | "less than average weight of the heart compared to the average for a particular strain" [RGD:Rat Genome Database submission] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0003084 | abnormal skeletal muscle fiber morphology | "anomalous structure of the skeletal muscle fibers, the large multinucleated cells that make up the skeletal muscles" [smb:Susan M. Bello, Mouse Genome Informatics Curator, Stedman s Medical Dictionary, 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0003124 | hypospadia | "a urethral opening located closer to the base of the penis and not at the tip" [smb:Susan M. Bello, Mouse Genome Informatics Curator, J:91491] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0003157 | impaired muscle relaxation | "reduced or absent ability of muscle to lengthen following contractions" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:92510] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0003205 | testicular atrophy | "wasting of the male reproductive glands resulting in reduced size" [RGD:Rat Genome Database submission] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0003448 | altered tumor morphology | "changes in the expected pathology for a given tumor type compared to controls" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0003534 | blind vagina | "presence the female reproductive canal that ends in a sac and does not connect to internal genitalia" [ncbi:Matthew Mailman, NCBI request, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0003550 | short perineum | "reduced length of the area between the genital organs and the anus that lies beneath the pelvic diaphragm" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
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MP:0003553 | abnormal foreskin morphology | "anomaly of the loose fold of skin that covers the penis" [ncbi:Matthew Mailman, NCBI request] |
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
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MP:0003557 | absent vas deferens | "absence of the secretory duct of the testicle that carries spermatozoa, running from the epididymis, of which it is the continuation, to the prostatic urethra where it terminates to form ejaculatory duct" [ncbi:Matthew Mailman, NCBI request, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0003607 | abnormal prostate physiology | "malfunction of the gland in males that secretes part of the seminiferous fluid" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0003642 | absent seminal gland | "absence of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens " [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0003698 | abnormal male reproductive system physiology | "anomaly in the function of the male organs associated with producing offspring " [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0003721 | increased tumor growth/size | "greater than expected development of tumorous growth when compared to controls" [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0003921 | abnormal left ventricle morphology | "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0003936 | abnormal reproductive system development | "developmental anomaly of any of the organs involved in the reproductive system" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Mkxtm1.1Asah/Mkxtm1.1Asah Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * CBA
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MP:0004145 | abnormal muscle electrophysiology | "anomaly in the function of the musculature as it relates to electrical phenomena" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0004502 | decreased incidence of chemically-induced tumors | "lower than normal frequency of tumor incidence induced by one or more chemical carcinogens or mutagens" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
Allelic Composition: Artm1.1Chc/Artm1.1Chc Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0004543 | abnormal sperm physiology | "anomaly in the normal function of spermatozoa" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0004565 | small myocardial fiber | "decreased size of the cardiac muscle fibers, the multinucleated muscle cells of the heart" [MGI:monikat "Monika Tomczuk, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0004727 | absent epididymis | "absence of the elongated structure connected to the posterior surface of the testis, consisting of the head, body, and tail, which turns sharply on itself to become the ductus deferens (vas deferens)" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Amhtm1Bhr/Amhtm1Bhr,ArTfm/Y Genetic Background: either: (involves 129P3/J * 129S7/SvEvBrd) or (involves: 129S7/SvEvBrd * C57BL/6)
Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1.1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6 * FVB/N
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MP:0004851 | increased testis weight | "greater average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0004852 | decreased testis weight | "reduced average weight of the male reproductive glands" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1.1Jdz/Y Genetic Background: involves: 129X1/SvJ * C57BL/6
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/Tg(Abpa-cre)1Cmal Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2 * SJL
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/Plekha5Tg(AMH-cre)1Flor Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
Allelic Composition: Artm1Jdz/Y,Tg(CMV-cre)1Cgn/0 Genetic Background: involves: 129X1/SvJ * BALB/cJ
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MP:0004856 | decreased ovary weight | "reduction in the average weight of the female reproductive gland containing the germ cells" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0004893 | decreased adiponectin level | "reduced concentration of a protein hormone that regulates glucose homeostasis and metabolism of lipids; it is normally produced by adipose tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0004901 | decreased male germ cell number | "reduced numbers of male germ cells whether they are undifferentiated or fully differentiated" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
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MP:0004905 | decreased uterus weight | "reduction in the weight of the female organ of gestation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0004910 | decreased seminal gland weight | "reduction in the weight of one or both of the two folded, sac shaped, glands that is a diverticulum of the ductus deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0004929 | decreased epididymis weight | "reduction in the average weight of the elongated structure connected to the posterior surface of the testis that transports, stores, and matures spermatozoa between testis and vas deferens" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl
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MP:0004933 | abnormal epididymis epithelium morphology | "any structural anomaly of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0004934 | epididymis epithelium degeneration | "pathological deterioration of the layer of secretory cells which lines the epididymis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0004958 | enlarged prostate | "increased size of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * DBA/2
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MP:0004961 | increased prostate weight | "greater than average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0004962 | decreased prostate weight | "reduction in the average weight of the gland in males that secretes part of the seminiferous fluid" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl
Allelic Composition: Artm3.1(AR)Ska/Y Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0004984 | increased osteoclast cell number | "greater than average number of the bone resorpting cells that remove bone tissue by degrading the mineralized matrix" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005117 | increased circulating pituitary hormone level | "greater than expected concentraton of any of the pituitary hormones in the blood" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Artm1Reb/Y Genetic Background: involves: 129S4/SvJaeSor
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
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MP:0005149 | abnormal gubernaculum morphology | "dysmorphology of the genitoinguinal ligaments that, in the male, connect the fetal testis to the developing scrotum, and, in the female, connect the ovaries to the uterus" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:55881] |
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Allelic Composition: ArTfm/Y,Insl3tm1Imad/Insl3tm1Imad Genetic Background: involves: 129/Sv * CD-1 * STOCK EdaTa
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MP:0005159 | azoospermia | "absence of living spermatozoa " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
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MP:0005187 | abnormal penis morphology | "anomalous structure of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0005188 | small penis | "in comparison to the norm, reduced size of the organ of copulation and urination in the male" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:66817] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005189 | abnormal anogenital distance | "in comparison to the norm, aberration in the measure of the length of space from the genitals to the anus" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005250 | Sertoli cell hypoplasia | "decreased number of cells of the seminiferous tubules that create the blood-testes barrier and enable spermatogenesis" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:70212] |
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Allelic Composition: Artm1Fcl/Y Genetic Background: involves: 129S2/SvPas * C57BL/6
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MP:0005293 | impaired glucose tolerance | "less than the normal response to oral consumption or intravenous injection of specified amounts of glucose and indicative of insulin resistance; measured by determining whole blood or plasma sugar level in a fasting state before and after taking glucose at specified intervals" [MeSH:National Library of Medicine - Medical Subject Headings , 2003] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005317 | increased triglyceride level | "higher than normal concentration of triacylglycerols " [Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005331 | insulin resistance | "diminished effectiveness of insulin in lowering plasma glucose levels" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:84260, pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005452 | abnormal body fat amount | "more or less than the normal total amount of connective tissue composed of fat cells" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0005455 | increased weight gain | "greater increase in body weight over existing weight when compared to the average increase in weight on the same diet, with equal energy (calorie) intake " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, J:42702] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005458 | increased percent body fat | "more fat, relative to the norm, as a percentage of total body weight" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator] |
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Allelic Composition: Disp1tm1Ptch/Disp1tm1Ptch Genetic Background: either: (involves: 129P2/OlaHsd) or (involves: 129/Sv * 129P2/OlaHsd) or (involves: 129P2/OlaHsd * C57BL/6) or (involves: 129P2/OlaHsd * Swiss Webster)
Allelic Composition: Artm1(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005536 | Leydig cell hypoplasia | "reduced numbers of the interstitial cells of the seminiferous tubules that secrete testosterone" [pvb:Pierre Vanden Borre , Mouse Genome Informatics Curator] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0005553 | increased circulating creatinine level | "greater than the normal blood concentration of this product of creatine catabolism; abnormal levels indicative of renal dysfunction" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005559 | increased circulating glucose level | "greater than the normal concentration in the blood of this major monosaccharide of the body; it is an important energy source" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, RGD:Rat Genome Database submission] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0005565 | increased blood urea nitrogen level | "high circulating concentration of nitrogen, in the form of urea; commonly used to measure renal function" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005598 | decreased ventricle muscle contractility | "reduced ability of the heart ventricle muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0005608 | cardiac interstitial fibrosis | "formation of fibrous tissue within the interstices of the heart as a result of repair or a reactive process" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, RGD:Rat Genome Database submission] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0005627 | increased circulating potassium level | "greater than the normal concentration in the blood of this alkaline metallic element, the most abundant intracellular ion; anomalies in the extracellular (circulating) concentration have important implications for the function of excitable tissues, such as nerve and muscle" [RGD:Rat Genome Database submission] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0005669 | increased circulating leptin level | "greater than the normal blood concentration of the peptide hormone secreted by white adipocytes and believed to regulate food intake and energy balance" [MeSH:National Library of Medicine - Medical Subject Headings, 2003, J:34751] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0006262 | testis tumor | "presence of abnormal rapidly proliferating cells in the testis, usually in the form of a distinct mass" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:60034] |
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0006308 | enlarged seminiferous tubules | "increased diameter of the tubules in the testes where spermatogenesis occurs" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0006369 | supernumerary incisors | "more than a pair, top and/or bottom, of the long pointed teeth that are the most anterior and prominent in the jaw" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0006378 | abnormal spermatogonia morphology | "anomaly in the number, structure or development of the large unspecialized male germ cells that give rise to spermatocytes" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0006379 | abnormal spermatocyte morphology | "anomaly in the number or structure of male germ cells that through meiosis give rise to spermatids " [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0006380 | abnormal spermatid morphology | "anomaly in the number or structure of the male germ cells that without further cell division give rise to mature spermatozoa" [ISBN:0-8036-0655-99 "Taber s Cyclopedic Medical Dictionary, 19th edition", MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0006420 | abnormal peritubular myoid cell morphology | "any structural anomaly of the flattened smooth myoepithelial cells of mesodermal origin that lie just outside the basal lamina of the seminiferous tubule" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0008214 | increased immature B cell number | "greater number of the cells of the B lymphocyte lineage that have undergone VDJ rearrangement of the heavy chain and V-J rearrangement of the light chain; these cells express IgM on the cell surface but have not yet been selected for self-reactivity" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease", MGI:cwg "Carroll-Ann W. Goldsmith, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
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MP:0008250 | abnormal myeloid leukocyte morphology | "any structural anomaly of a cell of the monocyte, granulocyte, or mast cell lineage" [CL:0000766] |
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Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
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MP:0008261 | arrest of male meiosis | "cessation of the progression of the process of nuclear division that results in sperm with one half the normal chromosome number of the original cell" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: ArTfm/Y Genetic Background: involves: STOCK EdaTa Atp7aMo-blo
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1.1Reb/Y Genetic Background: involves: 129S4/SvJaeSor * C57BL/6 * DBA/2J
Allelic Composition: Artm1.1Jdz/Y Genetic Background: B6.129X1-Artm1.1Jdz
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Chc/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S/SvEv * C57BL/6 * SJL
Allelic Composition: Amhr2tm3(cre)Bhr/Amhr2+,Artm1Chc/Y Genetic Background: involves: 129S/SvEv * C57BL/6
Allelic Composition: ArTfm/Y,Tg(TSPY)9Jshm/0 Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
Allelic Composition: ArTfm/Y Genetic Background: involves: NMRI * STOCK EdaTa Atp7aMo-blo
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MP:0008280 | male germ cell apoptosis | "presence of male germs cells that undergo programmed cell death" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
Allelic Composition: Artm1Verh/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0008892 | abnormal sperm flagellum | "any strucutral anomaly of the whiplike posterior filiform portion of the spermatozoon that provides sperm motility" [MESH:A05.360.490.890.840] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0009066 | decreased oviduct weight | "reduction in the average weight of the tube through which the ova pass from the ovary to the uterus" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Artm1.1Chc,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009073 | absent Wolffian ducts | "absence of the transient embryonic drainage tubes of the embryonic kidney (mesonephric tubules) that empty into the cloaca and later develop into the ductus deferens in the male" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1.1Verh/Y Genetic Background: involves: 129S1/Sv * 129X1/SvJ * Black Swiss * C57BL/6
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MP:0009115 | abnormal fat cell morphology | "any structural anomaly of a fat-storing cell found mostly in the abdominal cavity and subcutaneous tissue of mammals" [CL:0000449] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009198 | abnormal male genitalia morphology | "any structural anomaly of the masculine organs of reproduction or generation, external or internal" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Rnase10tm1(cre)Hht/Rnase10+ Genetic Background: involves: 129S7/SvEvBrd * C57BL/6
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MP:0009199 | abnormal external male genitalia morphology | "any structural anomaly of the external masculine genital organs, including the penis and scrotum" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm2Ska/Y,Gli1tm3(cre/ERT2)Alj/Gli1+ Genetic Background: involves: 129S6/SvEvTac * C57BL/6 * CBA
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MP:0009204 | absent external male genitalia | "absence of the external masculine genital organs, including the penis and scrotum" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009220 | prostate adenocarcinoma | "malignant neoplasm arising from prostate tissue" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Ptentm1Hwu/Ptentm1Hwu,Tg(Pbsn-cre)4Prb/0 Genetic Background: involves: 129S1/Sv * 129S4/SvJae * 129X1/SvJ * C57BL/6 * DBA/2
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MP:0009237 | kinked sperm flagellum | "a sharp bend or zigzag in the sperm tail" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0009238 | coiled sperm flagellum | "abnormal twisting of the sperm flagellum into coils or spirals" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0009243 | hairpin sperm flagellum | "a structural alteration where the sperm flagellum becomes bent back (folded) on itself to form a hairpin (loop) structure; a sharp hairpin-like bend formation can disrupt the axial structures and cause the sperm tail to become kinked" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0009283 | decreased gonadal fat pad weight | "less than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009285 | increased gonadal fat pad weight | "greater than average weight of the encapsulated adipose tissue associated with the ovaries or testes" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009294 | increased interscapular fat pad weight | |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009298 | increased mesenteric fat pad weight | |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0009302 | increased renal fat pad weight | |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009355 | increased liver triglyceride level | "higher than normal concentration of triacylglycerols in the liver" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0009403 | increased variability of skeletal muscle fiber size | "greater range or dispersion within a distribution of skeletal muscle fiber size within a muscle compared to controls" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009404 | centrally nucleated skeletal muscle fibers | "cell nuclei are located at a position in the center of the skeletal myofiber, instead of their normal location at the periphery of the fiber; may be indicative of centronuclear myopathy" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009413 | skeletal muscle fiber atrophy | "a wasting of skeletal muscle fibers resulting in a derangement of the skeletal muscle fibers; occurs with age, immobilization, weightlessness, malnutrition or denervation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009642 | abnormal blood homeostasis | "anomaly in the processes involved in the maintenance of an internal equilibrium of various functions or chemical or protein composition of the blood" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition", MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0009659 | striated fur | "hair or fur characterized by transverse, usually parallel, markings due to an anomaly in hair color, texture, or growth" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0009697 | abnormal copulation | "an anomaly in sexual union that normally enables the transfer of ejaculate (sperm) from male to female, sometimes resulting in the fertilization of an egg" [GO:0007620, MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0010031 | abnormal cranium size | "deviation from the average range of cranium size compared to normal" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0010045 | increased omental fat pad weight | "greater than average weight of the encapsulated adipose tissue associated with the fold of peritoneal tissue that extends from the stomach to the posterior abdominal wall after associating with the transverse colon" [ISBN:0-683-40008-8 "Stedman s Medical Dictionary, 27th edition"] |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010053 | decreased grip strength | "reduced ability to grasp and hold objects, often measured as time spent hanging from an object or wire" [ISBN:0471316393 "Crawley, JN, What s Wrong with my Mouse: Behavioral Phenotyping of Transgenic and Knockout Mice"] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm4(AR)Dmr/Ar+ Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0010182 | decreased susceptibility to weight gain | "smaller increase in body weight over time when compared to the average increase in weight on the same diet, with equal energy (calorie) intake" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1Verh/Y,Tg(Fabp4-cre)1Rev/0 Genetic Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
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MP:0010231 | transverse fur striping | "presence of stripes of pigmented hair, usually black, of variable degree and location in the coat" [MGI:llw2 "Linda Washburn, Mouse Genome Informatics Curator"] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0010308 | decreased tumor latency | "earlier onset of tumor occurrence than expected" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0010357 | increased prostate gland tumor incidence | "greater than the expected number of neoplams in the prostate gland occurring in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"] |
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Allelic Composition: Artm1(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
Allelic Composition: Artm2(AR)Dmr/Y,Tg(TRAMP)8247Ng/0 Genetic Background: involves: 129S1/Sv * C57BL/6
Allelic Composition: Artm3.1(AR)Ska/Y,Tg(KLKB1-cre/ERT2)1Pcn/0,Tg(TRAMP)8247Ng/0 Genetic Background: involves: C57BL/6 * C57BL/6J * CBA
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MP:0011088 | partial neonatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms within the neonatal period after birth (Mus: P0)" [MGI:csmith] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0011101 | partial prenatal lethality | "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith] |
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Allelic Composition: ArTfm EdaTa-25H/Y Genetic Background: involves: 101/H * C3H/HeH
Allelic Composition: ArTfm/Ar+,EdaTa-25H/Eda+ Genetic Background: involves: 101/H * C3H/HeH
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MP:0011532 | decreased urine major urinary protein level | "reduced amount in the urine of a family of alpha2-microglobulin-related liver secretory proteins that comprise a major protein component of mouse urine" [MGI:csmith] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0011533 | increased urine major urinary protein level | "increased amount in the urine of a family of alpha2-microglobulin-related liver secretory proteins that comprise a major protein component of mouse urine" [MGI:csmith] |
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Allelic Composition: Artm4(AR)Dmr/Ar+ Genetic Background: involves: 129S1/Sv * C57BL/6J
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MP:0013598 | Leydig cell hypertrophy | "increased size of the interstitial cells that are found adjacent to the seminiferous tubules in the testicle and produce testosterone in the presence of luteinizing hormone (LH)" [MGI:Anna] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
Allelic Composition: Artm1Jdz/Y,Tg(Abpa-cre)1Cmal/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * DBA/2
Allelic Composition: Artm1Jdz/Y,Plekha5Tg(AMH-cre)1Flor/0 Genetic Background: involves: 129X1/SvJ * C57BL/6 * SJL
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MP:0013600 | testis degeneration | "a retrogressive impairment of function or destruction of either or both of the male reproductive glands" [MGI:Anna] |
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Allelic Composition: Artm1Ska/Y,Tg(CMV-cre)1Ipc/? Genetic Background: involves: C57BL/6 * CBA
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MP:0013604 | abnormal adult Leydig cell differentiation | "atypical formation of or inability to produce the second or adult population of Leydig cells (ALCs) between birth and puberty; ALCs arise in the interstitium of adult testes from unknown progenitor cells and become the major source of androgens that control differentiation of the male reproductive tract and spermatogenesis; ALCs are not derived from fetal Leydig cells (FLCs), and the origin and the molecular events that control ALC differentiation are poorly understood" [PMID:23568777] |
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Allelic Composition: ArTfm/Y Genetic Background: STOCK EdaTa Atp7aMo-blo/+ +
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MP:0013899 | abnormal seminal vesicle epithelium morphology | "any structural anomaly of the pseudostratified columnar epithelium that lines the seminal vesicles and consists of tall, non-ciliated columnar cells and short, rounded basal cells that rest on the basal lamina; polarized columnar cells show features typical of secretory epithelium, including a well-developed Golgi complex, abundant rough endoplasmic reticulum, numerous mitochondria, and apical secretory vesicles; basal cells are the stem cells from which the columnar cells are derived" [ISBN:0781767903, ISBN:1455703079, MGI:Anna] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6 * FVB/NCrl
Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0013904 | abnormal seminal vesicle muscle layer morphology | "any structural anomaly of the thick muscular layer of the seminal vesicle consisting of an inner circular and outer longitudinal layer of smooth muscle which contracts during the emission phase of ejaculation to expel seminal vesicle fluid into the prostatic urethra" [MGI:Anna] |
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Allelic Composition: Artm1Jdz/Y,Tg(Pbsn-cre)20Fwan/? Genetic Background: involves: 129X1/SvJ * C57BL/6J * FVB/NCrl
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MP:0020039 | increased bone ossification | "increase in the formation of bone or of a bony substance, or the conversion of fibrous tissue or of cartilage into bone or a bony substance" [ORCID: orcid.org/0000-0003-4606-0597] |
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Allelic Composition: Artm1Chc/Y,Tmem163Tg(ACTB-cre)2Mrt/0 Genetic Background: involves: 129S/SvEv * C57BL/6J * FVB/N
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MP:0020355 | abnormal Sertoli cell barrier morphology | "any structural anomaly of the physical barrier found between adjacent Sertoli cells within the seminiferous tubules; the sertoli cell barrier consists of several types of cellular junctions including tight junctions, gap junctions and adhesion junctions, and divides the seminiferous tubules into the basal and apical (adluminal) compartments" [PMID:24713828 http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=572;epage=580;aulast=Jiang] |
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Allelic Composition: Gt(ROSA)26Sortm4(CAG-EGFP*)Nat/Gt(ROSA)26Sortm4(CAG-EGFP*)Nat Genetic Background: involves: 129 * C57BL/6
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MP:0020356 | abnormal Sertoli cell barrier function | "any functional anomaly of the physical barrier found between the blood vessels and the seminiferous tubules of the testes; this barrier between Sertoli cells is composed of tight junctions, basal ectoplasmic specializations, and desmosome-like junctions" [https://en.wikipedia.org/wiki/Blood%E2%80%93testis_barrier, PMID:24713828 http://www.ajandrology.com/article.asp?issn=1008-682X;year=2014;volume=16;issue=4;spage=572;epage=580;aulast=Jiang, PMID:24803656] |
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Allelic Composition: Artm1Reb/Y,Tg(Amh-cre)8815Reb/? Genetic Background: involves: 129S4/SvJaeSor * FVB/N
Allelic Composition: Artm2.1Reb/Ar+,Tg(Amh-cre)8815Reb/? Genetic Background: 129S(FVB)-Artm2.1Reb
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MP:0020378 | abnormal cell cytoskeleton morphology | "any anomaly in the structure of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm" [GO:0005856, MGI:mberry] |
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Allelic Composition: Artm4(AR)Dmr/Y Genetic Background: involves: 129S1/Sv * C57BL/6J
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