ENSGALG00000030879


Gallus gallus

Features
Gene ID: ENSGALG00000030879
  
Biological name :AR
  
Synonyms : androgen receptor / AR
  
Possible biological names infered from orthology : P10275 / P19091
  
Species: Gallus gallus
  
Chr. number: 4
Strand: 1
Band:
Gene start: 453408
Gene end: 497573
  
Corresponding Affymetrix probe sets: Gga.15098.1.S1_at (Chicken Array)   Gga.8155.1.S1_at (Chicken Array)   GgaAffx.2838.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000046062
NCBI entrez gene - 422165     See in Manteia.
RefSeq - NM_001040090
RefSeq Peptide - NP_001035179
swissprot - A0A1D5P088
Ensembl - ENSGALG00000030879
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 arENSDARG00000067976Danio rerio
 ARENSG00000169083Homo sapiens
 ArENSMUSG00000046532Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
PGR / progesterone receptor / P06401* / Q00175*ENSGALG0000001719533
NR3C2 / mineralocorticoid receptor / P08235* / nuclear receptor subfamily 3 group C member 2*ENSGALG0000001003531
NR3C1 / glucocorticoid receptor / P04150* / nuclear receptor subfamily 3 group C member 1*ENSGALG0000003299230
ESR1 / estrogen receptor / P03372* / P19785* / estrogen receptor 1*ENSGALG0000001297314
ESRRG / estrogen-related receptor gamma / P62508* / P62509* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSGALG0000000964514
ESRRB / estrogen related receptor beta / O95718* / Q61539* / Steroid hormone receptor ERR2 *ENSGALG0000004177514
ESR2 / estrogen receptor beta / O08537* / Q92731* / estrogen receptor 2*ENSGALG0000001180114
NR4A3 / nuclear receptor subfamily 4 group A member 3 / Q92570* / Q9QZB6*ENSGALG0000001356814
NR4A2 / nuclear receptor subfamily 4 group A member 2 / P43354* / Q06219*ENSGALG0000001253814


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001103  Androgen receptor
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0001701 in utero embryonic development IEA
 biological_processGO:0003073 regulation of systemic arterial blood pressure IEA
 biological_processGO:0003382 epithelial cell morphogenesis IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006357 regulation of transcription by RNA polymerase II IEA
 biological_processGO:0007283 spermatogenesis IEA
 biological_processGO:0007338 single fertilization IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0008285 negative regulation of cell proliferation IEA
 biological_processGO:0008584 male gonad development IEA
 biological_processGO:0009566 fertilization IEA
 biological_processGO:0009987 cellular process IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0010628 positive regulation of gene expression IEA
 biological_processGO:0019102 male somatic sex determination IEA
 biological_processGO:0030521 androgen receptor signaling pathway IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0033148 positive regulation of intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0033327 Leydig cell differentiation IEA
 biological_processGO:0035264 multicellular organism growth IEA
 biological_processGO:0042327 positive regulation of phosphorylation IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043410 positive regulation of MAPK cascade IEA
 biological_processGO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway IEA
 biological_processGO:0045597 positive regulation of cell differentiation IEA
 biological_processGO:0045720 negative regulation of integrin biosynthetic process IEA
 biological_processGO:0045726 positive regulation of integrin biosynthetic process IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0045945 positive regulation of transcription by RNA polymerase III IEA
 biological_processGO:0048608 reproductive structure development IEA
 biological_processGO:0048638 regulation of developmental growth IEA
 biological_processGO:0048645 animal organ formation IEA
 biological_processGO:0048808 male genitalia morphogenesis IEA
 biological_processGO:0050680 negative regulation of epithelial cell proliferation IEA
 biological_processGO:0050790 regulation of catalytic activity IEA
 biological_processGO:0051092 positive regulation of NF-kappaB transcription factor activity IEA
 biological_processGO:0051259 protein complex oligomerization IEA
 biological_processGO:0060520 activation of prostate induction by androgen receptor signaling pathway IEA
 biological_processGO:0060571 morphogenesis of an epithelial fold IEA
 biological_processGO:0060599 lateral sprouting involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060685 regulation of prostatic bud formation IEA
 biological_processGO:0060736 prostate gland growth IEA
 biological_processGO:0060740 prostate gland epithelium morphogenesis IEA
 biological_processGO:0060742 epithelial cell differentiation involved in prostate gland development IEA
 biological_processGO:0060748 tertiary branching involved in mammary gland duct morphogenesis IEA
 biological_processGO:0060749 mammary gland alveolus development IEA
 biological_processGO:0060769 positive regulation of epithelial cell proliferation involved in prostate gland development IEA
 biological_processGO:0061458 reproductive system development IEA
 biological_processGO:0071383 cellular response to steroid hormone stimulus IEA
 biological_processGO:0071394 cellular response to testosterone stimulus IEA
 biological_processGO:0072520 seminiferous tubule development IEA
 biological_processGO:1903076 regulation of protein localization to plasma membrane IEA
 biological_processGO:2001237 negative regulation of extrinsic apoptotic signaling pathway IEA
 cellular_componentGO:0000790 nuclear chromatin IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0016607 nuclear speck IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001085 RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003682 chromatin binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0004882 androgen receptor activity IEA
 molecular_functionGO:0005102 signaling receptor binding IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0005497 androgen binding IEA
 molecular_functionGO:0008013 beta-catenin binding IEA
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding IEA
 molecular_functionGO:0070974 POU domain binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Ub-specific processing proteases
RUNX2 regulates osteoblast differentiation


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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