ENSGALG00000011801


Gallus gallus

Features
Gene ID: ENSGALG00000011801
  
Biological name :ESR2
  
Synonyms : ESR2 / estrogen receptor beta
  
Possible biological names infered from orthology : estrogen receptor 2 / O08537 / Q92731
  
Species: Gallus gallus
  
Chr. number: 5
Strand: 1
Band:
Gene start: 53079224
Gene end: 53120964
  
Corresponding Affymetrix probe sets: Gga.314.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000019234
NCBI entrez gene - 395575     See in Manteia.
RefSeq - NM_204794
RefSeq Peptide - NP_990125
swissprot - F1NMB7
Ensembl - ENSGALG00000011801
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 esr2aENSDARG00000016454Danio rerio
 esr2bENSDARG00000034181Danio rerio
 ESR2ENSG00000140009Homo sapiens
 Esr2ENSMUSG00000021055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
ESR1 / estrogen receptor / P03372* / P19785* / estrogen receptor 1*ENSGALG0000001297350
ESRRB / estrogen related receptor beta / O95718* / Q61539* / Steroid hormone receptor ERR2 *ENSGALG0000004177531
ESRRG / estrogen-related receptor gamma / P62508* / P62509* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSGALG0000000964530
NR3C2 / mineralocorticoid receptor / P08235* / nuclear receptor subfamily 3 group C member 2*ENSGALG0000001003524
NR3C1 / glucocorticoid receptor / P04150* / nuclear receptor subfamily 3 group C member 1*ENSGALG0000003299224
PGR / progesterone receptor / P06401* / Q00175*ENSGALG0000001719523
NR4A3 / nuclear receptor subfamily 4 group A member 3 / Q92570* / Q9QZB6*ENSGALG0000001356823
NR4A2 / nuclear receptor subfamily 4 group A member 2 / P43354* / Q06219*ENSGALG0000001253822
AR / androgen receptor / P10275* / P19091*ENSGALG0000003087921


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR021064  Estrogen receptor beta, N-terminal
 IPR024178  Oestrogen receptor/oestrogen-related receptor
 IPR028355  Estrogen receptor beta/gamma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045893 positive regulation of transcription, DNA-templated IEA
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005739 mitochondrion IEA
 molecular_functionGO:0001046 core promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0030284 estrogen receptor activity IEA
 molecular_functionGO:0034056 estrogen response element binding IEA
 molecular_functionGO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
Nuclear Receptor transcription pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

1 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr