ENSGALG00000017195


Gallus gallus

Features
Gene ID: ENSGALG00000017195
  
Biological name :PGR
  
Synonyms : PGR / progesterone receptor
  
Possible biological names infered from orthology : P06401 / Q00175
  
Species: Gallus gallus
  
Chr. number: 1
Strand: 1
Band:
Gene start: 183242907
Gene end: 183281319
  
Corresponding Affymetrix probe sets: Gga.705.1.S1_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000027736
NCBI entrez gene - 396198     See in Manteia.
RefSeq - NM_205262
RefSeq Peptide - NP_990593
swissprot - F1NYP9
Ensembl - ENSGALG00000017195
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 pgrENSDARG00000035966Danio rerio
 PGRENSG00000082175Homo sapiens
 PgrENSMUSG00000031870Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
NR3C2 / mineralocorticoid receptor / P08235* / nuclear receptor subfamily 3 group C member 2*ENSGALG0000001003534
NR3C1 / glucocorticoid receptor / P04150* / nuclear receptor subfamily 3 group C member 1*ENSGALG0000003299231
AR / androgen receptor / P10275* / P19091*ENSGALG0000003087929
ESR1 / estrogen receptor / P03372* / P19785* / estrogen receptor 1*ENSGALG0000001297315
ESRRB / estrogen related receptor beta / O95718* / Q61539* / Steroid hormone receptor ERR2 *ENSGALG0000004177514
ESR2 / estrogen receptor beta / O08537* / Q92731* / estrogen receptor 2*ENSGALG0000001180114
ESRRG / estrogen-related receptor gamma / P62508* / P62509* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSGALG0000000964513
NR4A2 / nuclear receptor subfamily 4 group A member 2 / P43354* / Q06219*ENSGALG0000001253812
NR4A3 / nuclear receptor subfamily 4 group A member 3 / Q92570* / Q9QZB6*ENSGALG0000001356811


Protein motifs (from Interpro)
Interpro ID Name
 IPR000128  Progesterone receptor
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001542 ovulation from ovarian follicle IEA
 biological_processGO:0002070 epithelial cell maturation IEA
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0010629 negative regulation of gene expression IEA
 biological_processGO:0030879 mammary gland development IEA
 biological_processGO:0038001 paracrine signaling IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II IEA
 biological_processGO:0048286 lung alveolus development IEA
 biological_processGO:0050678 regulation of epithelial cell proliferation IEA
 biological_processGO:0050847 progesterone receptor signaling pathway IEA
 biological_processGO:0060748 tertiary branching involved in mammary gland duct morphogenesis IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0019899 enzyme binding IEA
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:0051117 ATPase binding IEA


Pathways (from Reactome)
Pathway description
HSP90 chaperone cycle for steroid hormone receptors (SHR)
Nuclear Receptor transcription pathway
SUMOylation of intracellular receptors
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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