ENSDARG00000034181


Danio rerio

Features
Gene ID: ENSDARG00000034181
  
Biological name :esr2b
  
Synonyms : esr2b / estrogen receptor 2b
  
Possible biological names infered from orthology : ESR2 / estrogen receptor 2 / Estrogen receptor beta / O08537 / Q92731
  
Species: Danio rerio
  
Chr. number: 13
Strand: 1
Band:
Gene start: 37022601
Gene end: 37072558
  
Corresponding Affymetrix probe sets: Dr.11725.1.S1_at (Zebrafish Array)   NM_174862_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000041299
Ensembl peptide - ENSDARP00000118673
Ensembl peptide - ENSDARP00000063411
NCBI entrez gene - 317733     See in Manteia.
RefSeq - NM_174862
RefSeq - XM_005156973
RefSeq Peptide - NP_777287
swissprot - B8JJL4
swissprot - B8JJL3
ZFIN ID - ZDB-GENE-030116-1
Ensembl - ENSDARG00000034181
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ESR2ENSGALG00000011801Gallus gallus
 ESR2ENSG00000140009Homo sapiens
 Esr2ENSMUSG00000021055Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645453
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411140
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084724
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926624
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486124
esrrgb / estrogen-related receptor gamma bENSDARG0000001169623
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503220
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596619
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453218
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700718
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208218
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585418
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797618
nr4a1 / nuclear receptor subfamily 4, group A, member 1 / P12813* / P22736*ENSDARG0000000079616
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104314
esrrd / estrogen-related receptor deltaENSDARG0000001506412


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR013088  Zinc finger, NHR/GATA-type
 IPR021064  Estrogen receptor beta, N-terminal
 IPR024178  Oestrogen receptor/oestrogen-related receptor
 IPR028355  Estrogen receptor beta/gamma


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030520 intracellular estrogen receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 biological_processGO:0043627 response to estrogen IDA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0005496 steroid binding IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0030284 estrogen receptor activity IDA
 molecular_functionGO:0038052 RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding IDA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA
 molecular_functionGO:1990239 steroid hormone binding IDA


Pathways (from Reactome)
Pathway description
PIP3 activates AKT signaling
Nuclear Receptor transcription pathway
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSDARG00000010478 Q90474 / hsp90aa1.1 / heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1 / P07900* / P07901* / HSP90AA1* / Heat shock protein HSP 90-alpha * / heat shock protein...  / complex
 ENSDARG00000016454 esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *  / reaction / complex
 ENSDARG00000004111 esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *  / reaction / complex
 ENSDARG00000034181 esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *  / complex / reaction
 ENSDARG00000038835 ppid / peptidylprolyl isomerase D / Q08752* / Q9CR16* / peptidylprolyl isomerase D (cyclophilin D)*  / complex
 ENSDARG00000037284 ptges3a / prostaglandin E synthase 3a (cytosolic) / PTGES3* / Q9R0Q7* / Q15185* / prostaglandin E synthase 3*  / complex






 

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