ENSDARG00000000796


Danio rerio

Features
Gene ID: ENSDARG00000000796
  
Biological name :nr4a1
  
Synonyms : nr4a1 / nuclear receptor subfamily 4, group A, member 1
  
Possible biological names infered from orthology : P12813 / P22736
  
Species: Danio rerio
  
Chr. number: 23
Strand: -1
Band:
Gene start: 32149269
Gene end: 32194397
  
Corresponding Affymetrix probe sets: Dr.9243.1.A1_at (Zebrafish Array)   NM_001002173_at (Zebrafish Genome Array with custom cdf files)   
  
Cross references: Ensembl peptide - ENSDARP00000141471
Ensembl peptide - ENSDARP00000145340
Ensembl peptide - ENSDARP00000001911
Ensembl peptide - ENSDARP00000128524
Ensembl peptide - ENSDARP00000130172
NCBI entrez gene - 431720     See in Manteia.
RefSeq - NM_001002173
RefSeq Peptide - NP_001002173
swissprot - A0A0R4IC41
swissprot - Q6GMG3
swissprot - X1WE73
ZFIN ID - ZDB-GENE-040704-11
Ensembl - ENSDARG00000000796
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 NR4A1ENSG00000123358Homo sapiens
 Nr4a1ENSMUSG00000023034Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
nr4a2a / nuclear receptor subfamily 4, group A, member 2a / NR4A2* / Q06219* / P43354* / nuclear receptor subfamily 4 group A member 2*ENSDARG0000001700751
nr4a2b / nuclear receptor subfamily 4, group A, member 2bENSDARG0000004453249
nr4a3 / nuclear receptor subfamily 4, group A, member 3 / Q92570* / Q9QZB6*ENSDARG0000005585443
esrrb / esrrga / estrogen-related receptor betaENSDARG0000000486120
esrrb / estrogen-related receptor beta / O95718*ENSDARG0000010084720
esrra / estrogen-related receptor alpha / O08580* / P11474* / Steroid hormone receptor ERR1 *ENSDARG0000006926619
esrrgb / estrogen-related receptor gamma bENSDARG0000001169619
esr2a / estrogen receptor 2a / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000001645418
nr3c2 / nuclear receptor subfamily 3, group C, member 2 / P08235*ENSDARG0000010208218
esr1 / estrogen receptor 1 / P03372* / P19785* / Estrogen receptor *ENSDARG0000000411118
esr2b / estrogen receptor 2b / ESR2* / O08537* / Q92731* / estrogen receptor 2* / Estrogen receptor beta *ENSDARG0000003418117
ar / androgen receptor / P10275* / P19091*ENSDARG0000006797616
nr3c1 / nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) / P04150* / nuclear receptor subfamily 3 group C member 1*ENSDARG0000002503216
pgr / progesterone receptor / P06401* / Q00175*ENSDARG0000003596614
esrrd / estrogen-related receptor deltaENSDARG0000001506411
FO681288.3 / ESRRG* / P62508* / P62509* / estrogen related receptor gamma* / Mus musculus estrogen-related receptor gamma (Esrrg), transcript variant 5, mRNA.*ENSDARG0000011104310


Protein motifs (from Interpro)
Interpro ID Name
 IPR000536  Nuclear hormone receptor, ligand-binding domain
 IPR001628  Zinc finger, nuclear hormone receptor-type
 IPR001723  Nuclear hormone receptor
 IPR003070  Orphan nuclear receptor
 IPR013088  Zinc finger, NHR/GATA-type


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006351 transcription, DNA-templated IEA
 biological_processGO:0006355 regulation of transcription, DNA-templated IEA
 biological_processGO:0030522 intracellular receptor signaling pathway IEA
 biological_processGO:0043401 steroid hormone mediated signaling pathway IEA
 cellular_componentGO:0005634 nucleus IEA
 molecular_functionGO:0003677 DNA binding IEA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IEA
 molecular_functionGO:0003707 steroid hormone receptor activity IEA
 molecular_functionGO:0004879 nuclear receptor activity IEA
 molecular_functionGO:0008270 zinc ion binding IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IEA
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
AKT phosphorylates targets in the nucleus
Nuclear Receptor transcription pathway


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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