ENSMUSG00000027804


Mus musculus

Features
Gene ID: ENSMUSG00000027804
  
Biological name :Ppid
  
Synonyms : peptidylprolyl isomerase D (cyclophilin D) / Ppid / Q9CR16
  
Possible biological names infered from orthology : peptidylprolyl isomerase D / Q08752
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: E3
Gene start: 79591342
Gene end: 79603650
  
Corresponding Affymetrix probe sets: 10492671 (MoGene1.0st)   1417057_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000029382
Ensembl peptide - ENSMUSP00000141423
NCBI entrez gene - 67738     See in Manteia.
MGI - MGI:1914988
RefSeq - XM_017319698
RefSeq - NM_026352
RefSeq - XM_006501943
RefSeq Peptide - NP_080628
swissprot - Q9CR16
swissprot - A0A0A6YW70
Ensembl - ENSMUSG00000027804
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ppidENSDARG00000038835Danio rerio
 PPIDENSGALG00000009451Gallus gallus
 PPIDENSG00000171497Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Ppig / A2AR02 / Peptidyl-prolyl cis-trans isomerase G / Q13427* / peptidylprolyl isomerase G*ENSMUSG0000004213336
Nktr / P30415 / NK-tumor recognition protein Putative peptidyl-prolyl cis-trans isomerase / P30414* / natural killer cell triggering receptor*ENSMUSG0000003252535


Protein motifs (from Interpro)
Interpro ID Name
 IPR002130  Cyclophilin-type peptidyl-prolyl cis-trans isomerase domain
 IPR011990  Tetratricopeptide-like helical domain superfamily
 IPR013026  Tetratricopeptide repeat-containing domain
 IPR019734  Tetratricopeptide repeat
 IPR020892  Cyclophilin-type peptidyl-prolyl cis-trans isomerase, conserved site
 IPR024936  Cyclophilin-type peptidyl-prolyl cis-trans isomerase
 IPR029000  Cyclophilin-like domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II IEA
 biological_processGO:0000413 protein peptidyl-prolyl isomerization IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0015031 protein transport IEA
 biological_processGO:0034389 lipid particle organization IEA
 biological_processGO:0042981 regulation of apoptotic process IBA
 biological_processGO:0043065 positive regulation of apoptotic process IEA
 biological_processGO:0045070 positive regulation of viral genome replication IEA
 biological_processGO:0050714 positive regulation of protein secretion IEA
 biological_processGO:0061077 chaperone-mediated protein folding IEA
 biological_processGO:0065003 protein-containing complex assembly IEA
 biological_processGO:0071492 cellular response to UV-A IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005730 nucleolus ISS
 cellular_componentGO:0005737 cytoplasm ISS
 cellular_componentGO:0005829 cytosol IEA
 molecular_functionGO:0003755 peptidyl-prolyl cis-trans isomerase activity IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0005528 FK506 binding TAS
 molecular_functionGO:0008134 transcription factor binding IEA
 molecular_functionGO:0016853 isomerase activity IEA
 molecular_functionGO:0030331 estrogen receptor binding ISS
 molecular_functionGO:0030544 Hsp70 protein binding ISS
 molecular_functionGO:0031072 heat shock protein binding IEA
 molecular_functionGO:0051879 Hsp90 protein binding IEA


Pathways (from Reactome)
Pathway description
ESR-mediated signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000071072 Ptges3 / Q9R0Q7 / Prostaglandin E synthase 3 / Q15185*  / complex
 ENSMUSG00000023944 P11499 / Hsp90ab1 / Heat shock protein HSP 90-beta / P08238* / heat shock protein 90 alpha family class B member 1*  / complex
 ENSMUSG00000027804 Ppid / Q9CR16 / peptidylprolyl isomerase D (cyclophilin D) / Q08752* / peptidylprolyl isomerase D*  / complex
 ENSMUSG00000021270 P07901 / Hsp90aa1 / Heat shock protein HSP 90-alpha / P07900* / heat shock protein 90 alpha family class A member 1*  / complex
 ENSMUSG00000019768 Esr1 / P19785 / Estrogen receptor / P03372* / estrogen receptor 1*  / complex
 ENSMUSG00000021055 Esr2 / O08537 / Estrogen receptor beta / Q92731* / estrogen receptor 2*  / complex






 

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