ENSGALG00000033212


Gallus gallus

Features
Gene ID: ENSGALG00000033212
  
Biological name :HSP90AA1
  
Synonyms : heat shock protein HSP 90-alpha / HSP90AA1
  
Possible biological names infered from orthology : heat shock protein 90 alpha family class A member 1 / P07900 / P07901
  
Species: Gallus gallus
  
Chr. number: 5
Strand: -1
Band:
Gene start: 49564706
Gene end: 49571912
  
Corresponding Affymetrix probe sets: Gga.4879.2.S1_at (Chicken Array)   GgaAffx.12967.1.S1_s_at (Chicken Array)   
  
Cross references: Ensembl peptide - ENSGALP00000048032
Ensembl peptide - ENSGALP00000060285
Ensembl peptide - ENSGALP00000056620
Ensembl peptide - ENSGALP00000050834
NCBI entrez gene - 423463     See in Manteia.
RefSeq - NM_001109785
RefSeq Peptide - NP_001103255
swissprot - A0A1L1RND0
swissprot - A0A1D5PUL6
swissprot - A0A1D5PDI9
swissprot - A0A1D5P5R0
Ensembl - ENSGALG00000033212
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 Q90474ENSDARG00000010478Danio rerio
 P07900ENSG00000080824Homo sapiens
 P07901ENSMUSG00000021270Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
HSP90AB1 / heat shock cognate protein HSP 90-beta / P08238* / P11499* / Heat shock protein HSP 90-beta * / heat shock protein 90 alpha family class B member 1*ENSGALG0000001017586
HSP90B1 / endoplasmin precursor / P14625* / P08113* / heat shock protein 90 beta family member 1* / heat shock protein 90, beta (Grp94), member 1*ENSGALG0000003378946
TRAP1 / TNF receptor associated protein 1 / Q12931* / Q9CQN1* / Heat shock protein 75 kDa, mitochondrial *ENSGALG0000003995129


Protein motifs (from Interpro)
Interpro ID Name
 IPR001404  Heat shock protein Hsp90 family
 IPR003594  Histidine kinase/HSP90-like ATPase
 IPR019805  Heat shock protein Hsp90, conserved site
 IPR020568  Ribosomal protein S5 domain 2-type fold
 IPR020575  Heat shock protein Hsp90, N-terminal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001934 positive regulation of protein phosphorylation IEA
 biological_processGO:0006457 protein folding IEA
 biological_processGO:0006950 response to stress IEA
 biological_processGO:0007004 telomere maintenance via telomerase IEA
 biological_processGO:0021955 central nervous system neuron axonogenesis IEA
 biological_processGO:0030010 establishment of cell polarity IEA
 biological_processGO:0031396 regulation of protein ubiquitination IEA
 biological_processGO:0032273 positive regulation of protein polymerization IEA
 biological_processGO:0033138 positive regulation of peptidyl-serine phosphorylation IEA
 biological_processGO:0045040 protein import into mitochondrial outer membrane IEA
 biological_processGO:0045429 positive regulation of nitric oxide biosynthetic process IEA
 biological_processGO:0048675 axon extension IEA
 biological_processGO:0050821 protein stabilization IEA
 biological_processGO:0051131 chaperone-mediated protein complex assembly IEA
 biological_processGO:0051897 positive regulation of protein kinase B signaling IEA
 biological_processGO:0051973 positive regulation of telomerase activity IEA
 biological_processGO:1902949 positive regulation of tau-protein kinase activity IEA
 biological_processGO:1903364 positive regulation of cellular protein catabolic process IEA
 biological_processGO:1905323 telomerase holoenzyme complex assembly IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005634 nucleus IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005829 cytosol IDA
 cellular_componentGO:0032587 ruffle membrane IEA
 cellular_componentGO:0032991 protein-containing complex IEA
 cellular_componentGO:0043025 neuronal cell body IEA
 cellular_componentGO:0043209 myelin sheath IEA
 cellular_componentGO:0044294 dendritic growth cone IEA
 cellular_componentGO:0044295 axonal growth cone IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm IEA
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016887 ATPase activity IEA
 molecular_functionGO:0030235 nitric-oxide synthase regulator activity IEA
 molecular_functionGO:0030911 TPR domain binding IEA
 molecular_functionGO:0031072 heat shock protein binding IPI
 molecular_functionGO:0042802 identical protein binding IEA
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0042826 histone deacetylase binding IEA
 molecular_functionGO:0048156 tau protein binding IEA
 molecular_functionGO:0051020 GTPase binding IEA
 molecular_functionGO:0051082 unfolded protein binding IEA
 molecular_functionGO:0051219 phosphoprotein binding IPI
 molecular_functionGO:0070182 DNA polymerase binding IEA
 molecular_functionGO:0097110 scaffold protein binding IEA
 molecular_functionGO:0097718 disordered domain specific binding IEA
 molecular_functionGO:1990782 protein tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
Signaling by ERBB2
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
Regulation of actin dynamics for phagocytic cup formation
eNOS activation
Regulation of PLK1 Activity at G2/M Transition
HSP90 chaperone cycle for steroid hormone receptors (SHR)
HSF1 activation
Attenuation phase
HSF1-dependent transactivation
Loss of Nlp from mitotic centrosomes
Recruitment of mitotic centrosome proteins and complexes
Loss of proteins required for interphase microtubule organization from the centrosome
Recruitment of NuMA to mitotic centrosomes
EPHB-mediated forward signaling
Sema3A PAK dependent Axon repulsion
VEGFA-VEGFR2 Pathway
VEGFR2 mediated vascular permeability
Anchoring of the basal body to the plasma membrane
Neutrophil degranulation
AURKA Activation by TPX2
Downregulation of ERBB2 signaling
ESR-mediated signaling
Estrogen-dependent gene expression


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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