18595


Mus musculus (NCBI)

Features
Gene ID: 18595
  
Biological name :
  
Synonyms : AI115593|CD140a|Pdgfr-2 / Pdgfra / platelet derived growth factor receptor, alpha polypeptide
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1421916_at (Mouse Genome 430 2.0 Array)   1421917_at (Mouse Genome 430 2.0 Array)   1438946_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1113820510
RefSeq - 1113820512
RefSeq - 134032016
RefSeq - 134032050
RefSeq - 568935054
RefSeq - 568935056
RefSeq - 568935058
RefSeq - NC_000071.6
RefSeq - NP_001076785.1
RefSeq - NP_001334647.1
RefSeq - NP_001334648.1
RefSeq - NP_035188.2
RefSeq - XP_006504324.1
RefSeq - XP_006504325.1
RefSeq - XP_006504326.1
RefSeq - XM_006504263.3
RefSeq - NM_001083316.2
RefSeq - NM_001347718.1
RefSeq - NM_001347719.1
RefSeq - NM_011058.3
RefSeq - NR_144636.1
RefSeq - XM_006504261.3
RefSeq - XM_006504262.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000029231 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001553 luteinization IMP
 biological_processGO:0001701 in utero embryonic development IMP
 biological_processGO:0002244 hematopoietic progenitor cell differentiation IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0006935 chemotaxis IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007204 positive regulation of cytosolic calcium ion concentration ISO
 biological_processGO:0007275 multicellular organism development IEA
 biological_processGO:0008210 estrogen metabolic process IGI
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008585 female gonad development IGI
 biological_processGO:0009653 anatomical structure morphogenesis IMP
 biological_processGO:0009887 animal organ morphogenesis IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010544 negative regulation of platelet activation ISO
 biological_processGO:0010863 positive regulation of phospholipase C activity ISO
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0016477 cell migration IMP
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0023019 signal transduction involved in regulation of gene expression IDA
 biological_processGO:0030154 cell differentiation IBA
 biological_processGO:0030198 extracellular matrix organization IMP
 biological_processGO:0030324 lung development IMP
 biological_processGO:0030325 adrenal gland development IGI
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0030539 male genitalia development IMP
 biological_processGO:0033327 Leydig cell differentiation IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0034614 cellular response to reactive oxygen species ISO
 biological_processGO:0035790 platelet-derived growth factor receptor-alpha signaling pathway ISO
 biological_processGO:0038091 positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway ISO
 biological_processGO:0042060 wound healing IMP
 biological_processGO:0042475 odontogenesis of dentin-containing tooth IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0043552 positive regulation of phosphatidylinositol 3-kinase activity ISO
 biological_processGO:0046777 protein autophosphorylation ISO
 biological_processGO:0048008 platelet-derived growth factor receptor signaling pathway ISO
 biological_processGO:0048015 phosphatidylinositol-mediated signaling ISO
 biological_processGO:0048146 positive regulation of fibroblast proliferation ISO
 biological_processGO:0048557 embryonic digestive tract morphogenesis IMP
 biological_processGO:0048701 embryonic cranial skeleton morphogenesis IMP
 biological_processGO:0048705 skeletal system morphogenesis IMP
 biological_processGO:0050731 positive regulation of peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0050920 regulation of chemotaxis ISO
 biological_processGO:0055003 cardiac myofibril assembly IGI
 biological_processGO:0060021 roof of mouth development IMP
 biological_processGO:0060325 face morphogenesis IMP
 biological_processGO:0060326 cell chemotaxis ISO
 biological_processGO:0060437 lung growth ISO
 biological_processGO:0061047 positive regulation of branching involved in lung morphogenesis ISO
 biological_processGO:0061298 retina vasculature development in camera-type eye IGI
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0070527 platelet aggregation ISO
 biological_processGO:0071230 cellular response to amino acid stimulus IDA
 biological_processGO:0072277 metanephric glomerular capillary formation IGI
 biological_processGO:2000739 regulation of mesenchymal stem cell differentiation ISO
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane ISO
 cellular_componentGO:0005902 microvillus IDA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0030054 cell junction ISO
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0031226 intrinsic component of plasma membrane ISO
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity ISO
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IEA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005018 platelet-derived growth factor alpha-receptor activity ISO
 molecular_functionGO:0005021 vascular endothelial growth factor-activated receptor activity ISO
 molecular_functionGO:0005161 platelet-derived growth factor receptor binding ISO
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0038085 vascular endothelial growth factor binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding ISO
 molecular_functionGO:0044877 protein-containing complex binding IDA
 molecular_functionGO:0048407 platelet-derived growth factor binding TAS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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