ENSMUSG00000042626


Mus musculus

Features
Gene ID: ENSMUSG00000042626
  
Biological name :Shc1
  
Synonyms : P98083 / Shc1 / SHC-transforming protein 1
  
Possible biological names infered from orthology : P29353 / SHC adaptor protein 1
  
Species: Mus musculus
  
Chr. number: 3
Strand: 1
Band: F1
Gene start: 89418443
Gene end: 89430027
  
Corresponding Affymetrix probe sets: 10493519 (MoGene1.0st)   1422853_at (Mouse Genome 430 2.0 Array)   1422854_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000115509
Ensembl peptide - ENSMUSP00000140336
Ensembl peptide - ENSMUSP00000123635
Ensembl peptide - ENSMUSP00000119293
Ensembl peptide - ENSMUSP00000117190
Ensembl peptide - ENSMUSP00000035361
Ensembl peptide - ENSMUSP00000091940
Ensembl peptide - ENSMUSP00000103040
NCBI entrez gene - 20416     See in Manteia.
MGI - MGI:98296
RefSeq - XM_006501213
RefSeq - NM_001113331
RefSeq - NM_011368
RefSeq - XM_006501212
RefSeq Peptide - NP_035498
RefSeq Peptide - NP_001106802
swissprot - D3Z2I8
swissprot - P98083
swissprot - D3YZV5
swissprot - D3YXZ9
swissprot - D3Z5U6
Ensembl - ENSMUSG00000042626
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 shc1ENSDARG00000075437Danio rerio
 SHC1ENSGALG00000039775Gallus gallus
 SHC1ENSG00000160691Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Shc2 / Q8BMC3 / SHC (Src homology 2 domain containing) transforming protein 2 / P98077* / SHC adaptor protein 2*ENSMUSG0000002031248
Shc4 / Q6S5L9 / SHC (Src homology 2 domain containing) family, member 4 / Q6S5L8* / SHC adaptor protein 4*ENSMUSG0000003510947
Shc3 / Q61120 / src homology 2 domain-containing transforming protein C3 / Q92529* / SHC adaptor protein 3*ENSMUSG0000002144845


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR006019  Phosphotyrosine interaction domain, Shc-like
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR029586  SHC-transforming protein 1
 IPR035676  SH2 adaptor protein C, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000165 MAPK cascade ISS
 biological_processGO:0000187 activation of MAPK activity ISS
 biological_processGO:0001525 angiogenesis IMP
 biological_processGO:0007165 signal transduction IEA
 biological_processGO:0007173 epidermal growth factor receptor signaling pathway IDA
 biological_processGO:0007507 heart development IMP
 biological_processGO:0008286 insulin receptor signaling pathway IBA
 biological_processGO:0031532 actin cytoskeleton reorganization IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0040008 regulation of growth IEA
 biological_processGO:0042127 regulation of cell proliferation IMP
 biological_processGO:0042742 defense response to bacterium ISO
 biological_processGO:0043066 negative regulation of apoptotic process ISO
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISO
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISO
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade ISO
 biological_processGO:0071363 cellular response to growth factor stimulus ISS
 biological_processGO:0098609 cell-cell adhesion IMP
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0005739 mitochondrion IEA
 cellular_componentGO:0005759 mitochondrial matrix IEA
 cellular_componentGO:0005829 cytosol TAS
 cellular_componentGO:0005886 plasma membrane IBA
 molecular_functionGO:0001784 phosphotyrosine residue binding ISO
 molecular_functionGO:0005158 insulin receptor binding ISO
 molecular_functionGO:0005159 insulin-like growth factor receptor binding ISO
 molecular_functionGO:0005168 neurotrophin TRKA receptor binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IPI
 molecular_functionGO:0046875 ephrin receptor binding IPI
 molecular_functionGO:0048408 epidermal growth factor binding IPI


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000280 thin ventricular wall "decreased depth of the cardiac wall of the heart ventricles" [J:45302]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0000291 enlarged pericardium "extended fibroserous membrane covering the heart and beginning of the great vessels" [J:29971]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0000295 poorly developed ventricular trabeculae "retarded differentation of the supporting bundles of muscular fibers lining the walls of the ventricles of the heart" [J:29971]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0000297 abnormal endocardial cushion morphology "malformation of the mounds of embryonic connective tissue that bulge into the embryonic atrioventricular canal; these mounds eventually fuse to form the valves between the right and left atrioventricular orifices" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0000358 abnormal cell content/ morphology "structural anomalies of the minute protoplasmic masses that make up organized tissues and which are the fundamental structural and functional units of living organisms" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0000627 abnormal mammary gland morphology "malformation of the milk-secreting gland that lies within the breast; usually rudimentary in males" [J:70183]
Show

Allelic Composition: Alpltm1Jlm/Alpltm1Jlm
Genetic Background: involves: 129S2/SvPas * C57BL/6

Allelic Composition: Shc1tm7Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1tm5Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0000774 reduced brain size "smaller appearance of the brain" [J:35802]
Show

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0000937 abnormal motor neuron morphology "malformation or absence of cells that innervate an effector (muscle or glandular) tissue; responsible for transmission of motor impulses" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, MGI:CLS, J:60159]
Show

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
Show

Allelic Composition: Tektm1Dmt/Tek+,Tie1tm1Jpa/Tie1tm1Jpa
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * CD-1

 MP:0001273 decreased metastatic potential 
Show

Allelic Composition: Shc1tm7Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1tm5Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0001393 ataxia "inability to coordinate voluntary muscular movements" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:67231]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm9Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm4Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm7Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001524 impaired limb coordination "reduced ability to organize limb movements to execute complex maneuvers, such as walking" [J:64962, MGI:CLS, J:17123]
Show

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm9Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm3Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm7Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0001544 abnormal cardiovascular system physiology "anomalous function of the blood, blood vessels, and/or the heart" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

 MP:0001614 abnormal vasculature "anomalies in the structure of development of the network of tubes that carries blood through the body" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0001661 extended life span "persistence of life for a longer period than is the norm for an organism" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0001722 pale yolk sac "bloodless yolk sac" [J:62571]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0001823 thymus hypoplasia "small size due to reduced cell number in the thymus" [J:23255]
Show

Allelic Composition: Icostm1Flv/Icostm1Flv,Tg(Cd4-Maf)6666Glm/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002080 prenatal lethality "death anytime between fertilization and E18.5" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002169 no phenotype detected "normal, viable and fertile appearance and behavior; indistinguishable from controls" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Shc1tm5Paw/Shc1tm5Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Isl1tm1(cre)Tmj/Isl1+,Shc1tm9Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Isl1tm1(cre)Tmj/Isl1+,Shc1tm9Paw/Shc1tm9.1Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0002189 abnormal myocardial trabeculae morphology "malformation of the supporting bundles of muscular fibers lining the walls of the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8, csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

 MP:0002407 abnormal double-negative T cell "anomalous structure, development, or number of the subset of T cells found in the thymus that express neither CD4 nor CD8" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator, Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Icostm1Flv/Icostm1Flv,Tg(Cd4-Maf)6666Glm/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0002652 thin myocardial wall "thinly developed cardiac muscle layers" [il:Ira Lu , Mouse Genome Informatics Curator, Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0002725 abnormal vein morphology "malformation of the blood vessels that carry blood towards the heart" [Stedman s Medical Dictionary , 27th edition:ISBN 0-683-40008-8]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0002912 abnormal excitatory postsynaptic potential "defect in the potential detected in postsynaptic cells when an excitatory impulse arrives at the synapse causing depolarization" [Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003229 abnormal vitelline vasculature "malformation in the vessels of the yolk sac" [smb:Susan M Bello, Mouse Genome Informatics Curator, J:93257]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0003312 abnormal locomotor coordination "reduced ability of an animal to maintain skillful and effective interaction of movements while engaging in locomotor activity" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
Show

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm9Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm3Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm4Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm7Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Shc1tm3Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Shc1tm3Paw/Shc1tm4Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0003566 abnormal cell adhesion "altered ability of a cell to adhere to another cell or to a non-cellular component of the environment" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0003674 oxidative stress "condition characterized by an accumulation of free radical groups in the body, which creates a potentially unstable and damaging cellular environment linked to tissue damage, accelerated aging, and degenerative disease; can result from many factors, including exposure to alcohol, medications, poor nutrition, trauma, cold or toxins; may be indicated by low antioxidant levels measured in blood plasma" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0003814 vascular smooth muscle cell hypoplasia "decreased numbers of smooth muscle cells in the vascular wall" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0003921 abnormal left ventricle morphology "structural anomaly of the left lower chamber of the heart " [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0004069 abnormal muscle spindle morphology "anomalous structure of the sensory organs in muscle that are involved in the stretch reflex" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator, Principles of Neural Science , 3rd edition:ISBN 0-8385-8034-3]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm4Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0004181 abnormal carotid artery morphology "malformation of any of the four arteries (two on each side of the neck; right and left internal carotid arteries, and right and left external carotid arteries) that deliver oxygen-rich blood from the heart to the head and brain" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0005092 decreased double-positive T cell count "less than the expected number of the subset of T cells found in the thymus that express both CD4 and CD8" [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7]
Show

Allelic Composition: Icostm1Flv/Icostm1Flv,Tg(Cd4-Maf)6666Glm/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0005140 decreased cardiac muscle contractility "inability or reduced ability of the heart muscle to shorten or to develop increased tension" [Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0005338 atherosclerotic lesions "thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005341 decreased susceptibility to atherosclerosis "less likely than the norm to develop thickening and loss of elasticity of arterial walls, involving lipid deposition and thickening of intimal layers within arteries" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005403 abnormal nerve conduction "anomaly in the act of transmitting electricity along a single nerve" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Pitx3tm1Mli/Pitx3tm1Mli
Genetic Background: involves: 129P2/OlaHsd

Allelic Composition: Shc1tm7Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0005590 increased vasodilation "greater than the expected or normal widening of the lumen of the blood vessels" [RGD:Rat Genome Database submission, Stedman s Medical Dictionary:ISBN 0-683-40008-8]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0005592 abnormal vascular smooth muscle morphology "structural anomaly of the nonstriated, involuntary muscle tissue of the blood vessels" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0005602 decreased angiogenesis "reduced process of blood vessel formation and the subsequent remodeling process; does not refer to the initial establishment of the vascular network" [RGD:Rat Genome Database submission]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0005621 abnormal cell physiology "aberration in the vital processes of the cell " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, hdene:Howard Dene , Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0006055 abnormal vascular endothelial cell morphology "malformation in the cells that line the vasculature" [smb:Susan M Bello, Mouse Genome Informatics Curator]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0008083 decreased single-positive T cell number "reduced number of T cells bearing either CD4 or CD8 markers on their surface" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Icostm1Flv/Icostm1Flv,Tg(Cd4-Maf)6666Glm/0
Genetic Background: involves: 129S1/Sv * C57BL/6

 MP:0008407 decreased cellular sensitivity to hydrogen peroxide "reduced incidence of cell death following exposure to hydrogen peroxide" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008411 decreased cellular sensitivity to ultraviolet irradiation "reduced incidence of cell death following exposure to ultraviolet irradiation" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008413 decreased cellular sensitivity to oxidative stress "reduced incidence of cell death or enhanced production of reactive oxygen species after exposure to a variety of stress conditions including ionizing radiation, exposure to xenobiotics, inflammation, and phagocytosis" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Mapk14tm1Mms/Mapk14tm1Mms
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008486 decreased muscle spindle number "reduced number of the sensory organs in muscle that are involved in the stretch reflex" [ISBN:0838580343 "Kandel ER, et al. Principles of Neural Science, 3rd edition"]
Show

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm9Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm3Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Myl1tm1(cre)Sjb/Myl1+,Shc1tm7Paw/Shc1tm9Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Shc1tm3Paw/Shc1tm7Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Shc1tm3Paw/Shc1tm4Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0009828 delayed tumor appearance "later onset of tumor occurence than expected, but with expected incidence" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
Show

Allelic Composition: Shc1tm7Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1tm5Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0010021 heart vascular congestion "obstruction of the normal flux of blood within the blood vessel network of the heart" [MGI:anna "Anna V. Anagnostopoulos, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

 MP:0010299 increased mammary gland tumor incidence "greater than the expected number of neoplasms in the mammary gland, usually in the form of a distinct mass, in a specific population in a given time period" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
Show

Allelic Composition: Shc1tm7Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1+,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm5Paw/Shc1tm5Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw,Tg(MMTV-PyVT)634Mul/0
Genetic Background: involves: 129S1/Sv * 129X1/SvJ * FVB/N

 MP:0011098 complete embryonic lethality during organogenesis "death of all organisms of a given genotype in a population between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

Allelic Composition: Shc1tm4Paw/Shc1tm4Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

Allelic Composition: Shc1tm8Paw/Shc1tm9.1Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011100 complete preweaning lethality "death of all organisms of a given genotype in a population between fertilization and weaning age (Mus: approximately 3-4 weeks of age)" [MGI:csmith]
Show

Allelic Composition: Casp9tm1Flv/Casp9tm1Flv
Genetic Background: B6.129S1-Casp9tm1Flv

 MP:0011101 partial prenatal lethality "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between fertilization and birth (Mus: approximately E18.5)" [MGI:csmith]
Show

Allelic Composition: Trp53tm1Att/Trp53tm1Att
Genetic Background: involves: 129S4/SvJae

Allelic Composition: Shc1tm6Paw/Shc1tm6Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0011108 partial embryonic lethality during organogenesis "the appearance of lower than Mendelian ratios of organisms of a given genotype due to death of some, but not all of the organisms between embryo turning and the completion of organogenesis (Mus: E9 to less than E14)" [MGI:csmith]
Show

Allelic Composition: Shc1tm8Paw/Shc1tm9.1Paw
Genetic Background: involves: 129S1/Sv * 129X1/SvJ

 MP:0020378 abnormal cell cytoskeleton morphology "any anomaly in the structure of the various filamentous elements that form the internal framework of cells, and typically remain after treatment of the cells with mild detergent to remove membrane constituents and soluble components of the cytoplasm" [GO:0005856, MGI:mberry]
Show

Allelic Composition: Gipc3ahl5-Black Swiss/Gipc3ahl5-Black Swiss,Ahl6Black Swiss/Ahl6Black Swiss
Genetic Background: involves: Black Swiss * CAST/EiJ

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000048583 Igf2 / P09535 / Insulin-like growth factor II Insulin-like growth factor II Preptin / P01344* / insulin like growth factor 2*  / reaction / complex
 ENSMUSG00000000215 Ins2 / P01326 / Insulin-2 Insulin-2 B chain Insulin-2 A chain / INS* / P01308* / insulin*  / complex / reaction
 ENSMUSG00000000182 Fgf23 / Q9EPC2 / Fibroblast growth factor 23 / Q9GZV9*  / complex / reaction
 ENSMUSG00000002664 Pspn / persephin / O60542*  / reaction / complex
 ENSMUSG00000005533 Igf1r / insulin like growth factor 1 receptor / P08069*  / reaction / complex
 ENSMUSG00000034116 Vav1 / P27870 / vav 1 oncogene / P15498* / vav guanine nucleotide exchange factor 1*  / complex / reaction
 ENSMUSG00000004508 Gab2 / GAB4* / Q2WGN9* / Q9UQC2* / GRB2 associated binding protein 2* / GRB2 associated binding protein family member 4*  / complex
 ENSMUSG00000005320 Fgfr4 / fibroblast growth factor receptor 4 / P22455*  / complex / reaction
 ENSMUSG00000018916 Csf2 / P01587 / Granulocyte-macrophage colony-stimulating factor / P04141* / colony stimulating factor 2*  / reaction / complex
 ENSMUSG00000020122 Egfr / Q01279 / Epidermal growth factor receptor / P00533*  / reaction / complex
 ENSMUSG00000026786 Q8R5A3 / Apbb1ip / amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein / Q7Z5R6* / amyloid beta precursor protein binding family B member 1 interacting protein*  / complex / reaction
 ENSMUSG00000059923 Grb2 / Q60631 / Growth factor receptor-bound protein 2 / P62993*  / reaction / complex
 ENSMUSG00000016933 Plcg1 / Q62077 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-1 / P19174* / phospholipase C gamma 1*  / complex / reaction
 ENSMUSG00000020395 Itk / Q03526 / Tyrosine-protein kinase ITK/TSK / Q08881* / IL2 inducible T cell kinase*  / complex
 ENSMUSG00000020689 Itgb3 / O54890 / Integrin beta-3 / P05106* / AC068234.1* / integrin subunit beta 3*  / reaction / complex
 ENSMUSG00000022309 Angpt1 / O08538 / Angiopoietin-1 / Q15389*  / reaction / complex
 ENSMUSG00000025089 Gfra1 / P97785 / GDNF family receptor alpha-1 / P56159*  / complex / reaction
 ENSMUSG00000024789 Jak2 / Janus kinase 2 / O60674*  / reaction / complex
 ENSMUSG00000024486 Hbegf / Q06186 / Proheparin-binding EGF-like growth factor Heparin-binding EGF-like growth factor / Q99075* / heparin binding EGF like growth factor*  / reaction / complex
 ENSMUSG00000024366 Gfra3 / O35118 / GDNF family receptor alpha-3 / O60609*  / complex / reaction
 ENSMUSG00000026117 Zap70 / P43404 / zeta-chain (TCR) associated protein kinase / P43403* / zeta chain of T cell receptor associated protein kinase 70*  / reaction
 ENSMUSG00000022144 Gdnf / P48540 / Mus musculus glial cell line derived neurotrophic factor (Gdnf), transcript variant 3, mRNA. / P39905* / glial cell derived neurotrophic factor*  / complex / reaction
 ENSMUSG00000022103 Gfra2 / O08842 / GDNF family receptor alpha-2 / O00451*  / complex / reaction
 ENSMUSG00000022781 Pak2 / Q8CIN4 / Serine/threonine-protein kinase PAK 2 PAK-2p27 PAK-2p34 / Q13177* / p21 (RAC1) activated kinase 2*  / complex / reaction
 ENSMUSG00000040751 Lat2 / Q9JHL0 / Linker for activation of T-cells family member 2 / Q9GZY6*  / complex / reaction
 ENSMUSG00000028465 Tln1 / P26039 / talin 1 / Q9Y490*  / reaction / complex
 ENSMUSG00000027316 Gfra4 / Q9JJT2 / GDNF family receptor alpha-4 / Q9GZZ7*  / reaction / complex
 ENSMUSG00000027665 P42337 / Pik3ca / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform / P42336* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha*  / complex / reaction
 ENSMUSG00000028017 Egf / P01132 / Mus musculus epidermal growth factor (Egf), transcript variant 3, mRNA. / P01133* / epidermal growth factor*  / reaction / complex
 ENSMUSG00000029377 Ereg / Q61521 / Proepiregulin Epiregulin / O14944* / epiregulin*  / complex / reaction
 ENSMUSG00000035804 Ins1 / P01325 / Insulin-1 Insulin-1 B chain Insulin-1 A chain / INS* / P01308* / insulin*  / complex / reaction
 ENSMUSG00000027646 Src / P05480 / Neuronal proto-onco tyrosine-protein kinase Src / P12931* / SRC proto-oncogene, non-receptor tyrosine kinase*  / complex / reaction
 ENSMUSG00000030110 Ret / P35546 / Proto-onco tyrosine-protein kinase receptor Ret Soluble RET kinase fragment Extracellular cell-membrane anchored RET cadherin 120 kDa fragment / P07949* / ret proto-oncogene*  / reaction / complex
 ENSMUSG00000002699 Lcp2 / Q60787 / Lymphocyte cytosolic protein 2 / Q13094*  / reaction / complex
 ENSMUSG00000062209 Erbb4 / Q61527 / Receptor tyrosine-protein kinase erbB-4 ERBB4 intracellular domain / Q15303* / erb-b2 receptor tyrosine kinase 4*  / complex / reaction
 ENSMUSG00000068758 Il3ra / P26952 / Interleukin-3 receptor subunit alpha / P26951*  / complex / reaction
 ENSMUSG00000031073 Fgf15 / O35622 / Fibroblast growth factor 15 / FGF19* / O95750* / fibroblast growth factor 19*  / reaction / complex
 ENSMUSG00000032737 Inppl1 / Q6P549 / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 2 / O15357* / inositol polyphosphate phosphatase like 1*  / complex / reaction
 ENSMUSG00000009376 Met / MET proto-oncogene, receptor tyrosine kinase / P08581*  / complex / reaction
 ENSMUSG00000041417 P26450 / Pik3r1 / phosphoinositide-3-kinase regulatory subunit 1 / P27986*  / complex / reaction
 ENSMUSG00000033721 Vav3 / Q9R0C8 / vav 3 oncogene / Q9UKW4* / vav guanine nucleotide exchange factor 3*  / complex / reaction
 ENSMUSG00000009621 Vav2 / Q60992 / vav 2 oncogene / P52735* / vav guanine nucleotide exchange factor 2*  / complex / reaction
 ENSMUSG00000026288 Inpp5d / Q9ES52 / Phosphatidylinositol 3,4,5-trisphosphate 5-phosphatase 1 / Q92835* / inositol polyphosphate-5-phosphatase D*  / reaction / complex
 ENSMUSG00000058488 Kl / O35082 / Klotho Klotho peptide / klotho* / Q9UEF7*  / reaction / complex
 ENSMUSG00000024241 Sos1 / Q62245 / Son of sevenless homolog 1 / Q07889* / SOS Ras/Rac guanine nucleotide exchange factor 1*  / reaction / complex
 ENSMUSG00000043733 P35235 / Ptpn11 / Tyrosine-protein phosphatase non-receptor type 11 / Q06124* / protein tyrosine phosphatase, non-receptor type 11*  / complex / reaction
 ENSMUSG00000032462 Pik3cb / Q8BTI9 / Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform / P42338* / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta*  / complex / reaction
 ENSMUSG00000082361 Btc / Q05928 / Probetacellulin Betacellulin / P35070* / betacellulin*  / complex / reaction
 ENSMUSG00000031712 Il15 / P48346 / Interleukin-15 / P40933*  / complex
 ENSMUSG00000018166 Erbb3 / Q61526 / Receptor tyrosine-protein kinase erbB-3 / P21860* / erb-b2 receptor tyrosine kinase 3*  / complex
 ENSMUSG00000031304 Il2rg / P34902 / Cytokine receptor common subunit gamma / P31785* / AL590764.2* / interleukin 2 receptor subunit gamma*  / complex
 ENSMUSG00000068227 Il2rb / P16297 / Interleukin-2 receptor subunit beta / P14784*  / complex
 ENSMUSG00000032311 Nrg4 / Q9WTX4 / Pro-neuregulin-4, membrane-bound isoform Neuregulin-4 / Q8WWG1* / neuregulin 4*  / complex / reaction
 ENSMUSG00000029195 Klb / Q99N32 / Beta-klotho / Q86Z14* / klotho beta*  / complex / reaction
 ENSMUSG00000023206 Il15ra / Q60819 / Interleukin-15 receptor subunit alpha Soluble interleukin-15 receptor subunit alpha / Q13261* / interleukin 15 receptor subunit alpha*  / complex
 ENSMUSG00000071713 Csf2rb / P26955 / Mus musculus colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) (Csf2rb), transcript variant 1, mRNA. / P32927* / colony stimulating factor ...  / complex / reaction
 ENSMUSG00000071714 P26954 / Csf2rb2 / Interleukin-3 receptor class 2 subunit beta / CSF2RB* / P32927* / colony stimulating factor 2 receptor beta common subunit*  / complex / reaction
 ENSMUSG00000039936 O35904 / Pik3cd / phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta / O00329*  / complex / reaction
 ENSMUSG00000042351 Grap2 / O89100 / GRB2-related adaptor protein 2 / O75791*  / complex / reaction
 ENSMUSG00000030265 Kras / P32883 / GTPase KRas GTPase KRas, N-terminally processed / P01116* / KRAS proto-oncogene, GTPase*  / reaction
 ENSMUSG00000042626 Shc1 / P98083 / SHC-transforming protein 1 / P29353* / SHC adaptor protein 1*  / complex / reaction
 ENSMUSG00000055254 Ntrk2 / P15209 / BDNF/NT-3 growth factors receptor / Q16620* / neurotrophic receptor tyrosine kinase 2*  / complex / reaction
 ENSMUSG00000028864 Hgf / Q08048 / Hepatocyte growth factor Hepatocyte growth factor alpha chain Hepatocyte growth factor beta chain / P14210* / hepatocyte growth factor*  / reaction / complex
 ENSMUSG00000031565 Fgfr1 / P16092 / Fibroblast growth factor receptor 1 / P11362*  / reaction / complex
 ENSMUSG00000062312 Erbb2 / P70424 / Receptor tyrosine-protein kinase erbB-2 / P04626* / erb-b2 receptor tyrosine kinase 2*  / complex
 ENSMUSG00000031834 O08908 / Pik3r2 / Phosphatidylinositol 3-kinase regulatory subunit beta / O00459* / AC007192.1* / phosphoinositide-3-kinase regulatory subunit 2*  / reaction / complex
 ENSMUSG00000004266 Ptpn6 / P29351 / protein tyrosine phosphatase, non-receptor type 6 / P29350*  / complex
 ENSMUSG00000025499 Hras / Q61411 / GTPase HRas GTPase HRas, N-terminally processed / P01112* / HRas proto-oncogene, GTPase*  / reaction
 ENSMUSG00000001847 Rac1 / P63001 / RAS-related C3 botulinum substrate 1 / P63000* / Rac family small GTPase 1*  / reaction / complex
 ENSMUSG00000031714 Gab1 / Q9QYY0 / GRB2-associated-binding protein 1 / Q13480*  / complex
 ENSMUSG00000060275 Nrg2 / neuregulin 2 / O14511*  / complex
 ENSMUSG00000005534 Insr / P15208 / Insulin receptor Insulin receptor subunit alpha Insulin receptor subunit beta / P06213* / insulin receptor*  / complex / reaction
 ENSMUSG00000034330 Plcg2 / Q8CIH5 / 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma-2 / P16885* / phospholipase C gamma 2*  / complex / reaction
 ENSMUSG00000032312 Csk / P41241 / Tyrosine-protein kinase CSK / P41240* / C-terminal Src kinase*  / complex / reaction
 ENSMUSG00000031264 Btk / P35991 / Tyrosine-protein kinase BTK / Q06187* / Bruton tyrosine kinase*  / reaction / complex
 ENSMUSG00000030742 Lat / O54957 / Linker for activation of T-cells family member 1 / O43561* / linker for activation of T cells*  / reaction / complex
 ENSMUSG00000030774 Pak1 / Mus musculus p21 protein (Cdc42/Rac)-activated kinase 1 (Pak1), transcript variant 3, mRNA. / Q13153* / p21 (RAC1) activated kinase 1*  / reaction / complex
 ENSMUSG00000028771 P35831 / Ptpn12 / protein tyrosine phosphatase, non-receptor type 12 / Q05209*  / reaction / complex
 ENSMUSG00000052681 Rap1b / Q99JI6 / RAS related protein 1b / P61224* / RAP1B, member of RAS oncogene family*  / complex / reaction
 ENSMUSG00000036117 Il5 / P04401 / Interleukin-5 / P05113*  / complex / reaction
 ENSMUSG00000050965 Prkca / protein kinase C, alpha / P17252*  / reaction
 ENSMUSG00000063065 Mapk3 / Q63844 / Mitogen-activated protein kinase 3 / P27361*  / reaction
 ENSMUSG00000006386 Tek / Q02858 / TEK receptor tyrosine kinase / Q02763*  / complex / reaction
 ENSMUSG00000021457 Syk / P48025 / spleen tyrosine kinase / P43405* / spleen associated tyrosine kinase*  / reaction
 ENSMUSG00000000409 Lck / P06240 / Proto-onco tyrosine-protein kinase LCK / P06239* / LCK proto-oncogene, Src family tyrosine kinase*  / reaction
 ENSMUSG00000020053 Igf1 / P05017 / Insulin-like growth factor I / P05019* / insulin like growth factor 1*  / reaction / complex
 ENSMUSG00000039481 Nrtn / P97463 / Neurturin / Q99748*  / complex / reaction
 ENSMUSG00000028539 Artn / Q9Z0L2 / Artemin / Q5T4W7*  / complex / reaction
 ENSMUSG00000068798 Rap1a / P62835 / RAS-related protein 1a / P62834* / RAP1A, member of RAS oncogene family*  / reaction / complex
 ENSMUSG00000059326 Csf2ra / Q00941 / Granulocyte-macrophage colony-stimulating factor receptor subunit alpha / P15509* / colony stimulating factor 2 receptor alpha subunit*  / reaction / complex
 ENSMUSG00000034664 Itga2b / Q9QUM0 / integrin alpha 2b / P08514* / integrin subunit alpha 2b*  / complex / reaction
 ENSMUSG00000005364 Il5ra / P21183 / Interleukin-5 receptor subunit alpha / Q01344*  / reaction / complex






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2024
contact: otassy@igbmc.fr