ENSMUSG00000031712


Mus musculus

Features
Gene ID: ENSMUSG00000031712
  
Biological name :Il15
  
Synonyms : Il15 / Interleukin-15 / P48346
  
Possible biological names infered from orthology : P40933
  
Species: Mus musculus
  
Chr. number: 8
Strand: -1
Band: C2
Gene start: 82331632
Gene end: 82403222
  
Corresponding Affymetrix probe sets: 10579958 (MoGene1.0st)   1418219_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000034148
Ensembl peptide - ENSMUSP00000147319
Ensembl peptide - ENSMUSP00000147848
Ensembl peptide - ENSMUSP00000148256
Ensembl peptide - ENSMUSP00000147312
NCBI entrez gene - 16168     See in Manteia.
MGI - MGI:103014
RefSeq - XM_011248314
RefSeq - XM_006530712
RefSeq - XM_006530713
RefSeq - XM_006530714
RefSeq - XM_006530715
RefSeq - XM_011248312
RefSeq - XM_011248313
RefSeq - NM_001254747
RefSeq - NM_008357
RefSeq - XM_006530705
RefSeq - XM_006530706
RefSeq - XM_006530707
RefSeq - XM_006530708
RefSeq - XM_006530709
RefSeq - XM_006530710
RefSeq - XM_006530711
RefSeq Peptide - NP_001241676
RefSeq Peptide - NP_032383
swissprot - A0A1B0GQZ8
swissprot - Q3U1Z6
swissprot - A0A1B0GQZ2
swissprot - P48346
Ensembl - ENSMUSG00000031712
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 IL15ENSGALG00000009870Gallus gallus
 IL15ENSG00000164136Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
No match


Protein motifs (from Interpro)
Interpro ID Name
 IPR003443  Interleukin-15/Interleukin-21 family
 IPR009079  Four-helical cytokine-like, core
 IPR020439  Interleukin-15
 IPR020466  Interleukin-15, mammal


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001779 natural killer cell differentiation IGI
 biological_processGO:0001866 NK T cell proliferation IMP
 biological_processGO:0006954 inflammatory response IEA
 biological_processGO:0006955 immune response IEA
 biological_processGO:0007260 tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0007568 aging IEA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010469 regulation of signaling receptor activity IEA
 biological_processGO:0014732 skeletal muscle atrophy IEA
 biological_processGO:0030212 hyaluronan metabolic process IEA
 biological_processGO:0031667 response to nutrient levels IEA
 biological_processGO:0032740 positive regulation of interleukin-17 production IEA
 biological_processGO:0032819 positive regulation of natural killer cell proliferation IDA
 biological_processGO:0032825 positive regulation of natural killer cell differentiation IMP
 biological_processGO:0035723 interleukin-15-mediated signaling pathway IEA
 biological_processGO:0042102 positive regulation of T cell proliferation IMP
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein IEA
 biological_processGO:0045062 extrathymic T cell selection IMP
 biological_processGO:0045580 regulation of T cell differentiation IMP
 biological_processGO:0048469 cell maturation IGI
 biological_processGO:0048535 lymph node development IMP
 biological_processGO:0048662 negative regulation of smooth muscle cell proliferation IEA
 biological_processGO:0050691 regulation of defense response to virus by host IMP
 biological_processGO:0050778 positive regulation of immune response IMP
 biological_processGO:0071305 cellular response to vitamin D IEA
 biological_processGO:1904100 positive regulation of protein O-linked glycosylation IMP
 cellular_componentGO:0005576 extracellular region IEA
 cellular_componentGO:0005615 extracellular space IEA
 cellular_componentGO:0005654 nucleoplasm IEA
 cellular_componentGO:0005737 cytoplasm IDA
 cellular_componentGO:0005829 cytosol IEA
 cellular_componentGO:0009986 cell surface IEA
 cellular_componentGO:0016607 nuclear speck IEA
 molecular_functionGO:0005125 cytokine activity IMP
 molecular_functionGO:0005126 cytokine receptor binding IEA


Pathways (from Reactome)
Pathway description
Interleukin-15 signaling


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
 MP:0000220 increased monocyte count "greater than normal monocyte numbers" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0000685 abnormal immune system morphology "morphological anomalies in the organs or cells associated with the development and formation of lymphocytes" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001262 decreased body weight "lower than normal average weight " [J:61295]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001513 limb grasping "mice clasp front and/or hind feet almost immediately upon being lifted by tail" [cml:Cathleen M. Lutz , Mouse Genome Informatics Curator]
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Allelic Composition: Ift88tm1.1(KOMP)Vlcg/Ift88+
Genetic Background: C57BL/6N-Ift88tm1.1(KOMP)Vlcg/J

 MP:0001790 abnormal immune system physiology "deviation from the normal function of the immune system " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001793 altered susceptibility to infection "a change in the likelihood that an organism will develop ill effects from a pathogenic invasion or from components of or toxins produced by pathogens " [Stedman s Medical Dictionary:ISBN 0-683-40008-8, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001805 decreased IgG "less than normal immunoglobulin class G level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0001806 decreased IgM "less than normal immunoglobulin class M level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002083 premature death "death after 3 weeks of age, but before normal life span" [csmith:Cynthia L. Smith , Mouse Genome Informatics Curator]
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Allelic Composition: Acot13tm1Deco/Acot13tm1Deco
Genetic Background: Not Specified

Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0002217 small lymph nodes "lymph nodes of decreased size" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002376 abnormal dendritic cell physiology "failure or atypical function of the immunocompetent cells of the lymphoid and hemopoietic systems and skin, which function to process antigens and present them to T cells, thus stimulating cellular immunity" [MeSH:National Library of Medicine - Medical Subject Headings , 2003, J:85808]
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Allelic Composition: Il2rgtm1Wjl/Il2rgtm1Wjl
Genetic Background: B6.129S4-Il2rgtm1Wjl/J

 MP:0002460 decreased circulating immunoglobulin concentration "less than normal immunoglobulin level" [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0002619 abnormal lymphocyte morphology/development "anomalous structure, differentiation, or number of the white blood cells formed in the body s lymphoid tissue" [MeSH:National Library of Medicine - Medical Subject Headings , 2003]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003009 abnormal cytokine secretion "impairment or increase of the cellular release of any of the non-antibody proteins made by inflammatory leukocytes and some non-leukocytic cells that affect the behavior of other cells " [Immunobiology , The Immune System in Health and Disease:ISBN 0-8153-1691-7, smb:Susan M. Bello , Mouse Genome Informatics Curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003845 abnormal decidualization "disrupted proliferation, differentiation or transformation of endometrial stromal cells into decidual cells in the maternal uterus following embryo implantation" [anna:Anna Anagnostopoulos, Mouse Genome Informatics Curator, J:43609, J:48920]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0003995 abnormal uterine artery morphology "malformation of the branch of the internal iliac artery that supplies the uterus and the upper part of the vagina" [monikat:Monika Tomczuk, Mouse Genome Informatics Curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004392 abnormal CD8-positive T cell physiology "abnormal function of the subset of T lymphocytes that express the CD8 marker on the cell surface" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0004794 increased anti-nuclear antigen antibody level "elevated level of antibodies to nuclear antigens present in the sera" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0004801 increased susceptibility to systemic lupus erythematosus "greater likelihood that an organism will develop inflammatory connective tissue symptoms characteristic of lupus including skin rash, arthritis and inflammation of different organs" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Acot13tm1Deco/Acot13tm1Deco
Genetic Background: Not Specified

Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0004974 decreased regulatory T cell number "reduced number of the specialized subpopulation of T cells that act to suppress activation of the immune system and thus maintain immune system homeostasis and prevent pathological self-reactivity" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005027 increased susceptibility to parasitic infection "greater likelihood that an organism will develop ill effects from a parasitic infection or from components of or toxins produced by parasites " [cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005070 defective NK cell cytolysis "impaired ability of these cells to destroy or dissolve targeted cells" [Stedman s Medical Dictionary:ISBN 0-683-40008-8, J:6213]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0005616 decreased susceptibility to type IV hypersensitivity reaction "less likelihood of or resistance to developing an antigen-elicited cellular immune reaction that results in tissue damage, but does not require Ab participation; the response is seen at the area of contact" [Pathology:ISBN 0-397-51047-0, cwg:Carroll-Ann W. Goldsmith , Mouse Genome Informatics curator]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008038 abnormal NK T cell number "deviation from the normal number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
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Allelic Composition: Il17rbtm1Hwata/Il17rbtm1Hwata
Genetic Background: C.Cg-Il17rbtm1Hwata

 MP:0008040 decreased NK T cell number "reduced number of the distinct lineage of T cells expressing natural killer cell markers and having T cell receptors characterized by the usage of a restricted repertoire of variable region gene segments" [GO:0001865]
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Allelic Composition: Il17rbtm1Hwata/Il17rbtm1Hwata
Genetic Background: C.Cg-Il17rbtm1Hwata

 MP:0008045 decreased NK cell number "reduction in the number of non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Rag2tm1Fwa/Rag2tm1Fwa
Genetic Background: involves: 129S/SvEv * C57BL/6

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Myctm1Atp/Myc+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15m1Hwata/Il15m1Hwata
Genetic Background: Not Specified

 MP:0008047 absent uterine NK cells "absence of the uterine subset of the non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
Show

Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008050 decreased memory T cell number "reduced number of the set of long-lived T cells differentiated from T cells activated by a specific antigen encountered during a past immune response" [adiehl:Alex Diehl_MGI GO curator, Biology-Online.org:http://www.biology-online.org/, MGI:rbabiuk "Randall Babiuk, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15tm1Imx/Il15+,Myctm1Atp/Myc+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Myctm1Atp/Myc+
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008053 abnormal NK cell differentiation "atypical production of or inability to produce the non-T, non-B lymphocytes, having a granular morphology and which are important in innate immunity to viruses and other intracellular pathogens; in addition, these cells can kill certain tumor cells" [ISBN:0-8153-1691-7 "Immunobiology, The Immune System in Health and Disease"]
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Allelic Composition: Eomestm1.1Twa/?,Il15tm1Imx/Il15tm1Imx
Genetic Background: involves: C57BL/6 * C57BL/6N

 MP:0008079 decreased CD8-positive T cell number "reduction in the number of the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15tm1Imx/Il15tm1Imx
Genetic Background: C57BL/6NTac-Il15tm1Imx/Tac

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Itktm1Ljb/Itktm1Ljb
Genetic Background: involves: 129 * C57BL/6 * C57BL/10

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Il7rtm1.1Asin/Il7rtm1Imx,Tg(Cd8a*-cre)#Asin/0
Genetic Background: involves: 129S7/SvEvBrd * C57BL/6

 MP:0008080 abnormal CD8-positive T cell differentiation "atypical production of or inability to produce the regulatory subset of T lymphocytes that are involved in MHC class I restricted interactions" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Il15tm1Imx/Il15tm1Imx
Genetic Background: C57BL/6NTac-Il15tm1Imx/Tac

 MP:0008127 decreased dendritic cell number "reduction in the number of a cells of hematopoietic origin, typically resident in particular tissues, specialized in the uptake, processing, and transport of antigens to lymph nodes for the purpose of stimulating an immune response via T cell activation" [ISBN:0781735149, MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008363 decreased CD8-positive, gamma-delta intraepithelial T cell number "reduced number of a CD8-positive, gamma-delta T cell of the columnar epithelia such as in the gastrointestinal tract; intraepithelial T cells often have distinct developmental pathways and activation requirements" [CL:0000803, ISBN:0781735149]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008470 abnormal spleen B cell follicle morphology "any structural anomaly of the area of the white pulp where the affinity maturation of B cells and the generation of memory B cells and plasma cells occur" [PMID:17495967]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0008499 increased IgG1 level "greater than normal immunoglobulin class G1 level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0008500 increased IgG2a level "greater than normal immunoglobulin class G2a level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0008501 increased IgG2b level "greater than normal immunoglobulin class G2b level" [MGI:tmeehan "Terry Meehan, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0008567 decreased interferon-gamma secretion "reduction in the production or release of the major interferon produced by mitogenically or antigenically stimulated lymphocytes that is involved in immunoregulation" [MESH:D12.644.276.374.440.893]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

Allelic Composition: Il15m1Hwata/Il15m1Hwata
Genetic Background: Not Specified

 MP:0008568 abnormal interleukin secretion "anomaly in the production or cellular release of soluble factors which stimulate growth-related activities of leukocytes and other cell types, that can act to enhance cell proliferation and differentiation, DNA synthesis, secretion of other biologically active molecules and responses to immune and inflammatory stimuli" [MESH:D12.644.276.374.465]
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Allelic Composition: Il15m1Hwata/Il15m1Hwata
Genetic Background: Not Specified

 MP:0008664 decreased interleukin-12 secretion "reduction in the production or release of a heterodimeric cytokine that plays a role in innate and adaptive immune responses; it is produced by dendritic cells, macrophages and a variety of other immune cells and plays a role in the stimulation of interferon-gamma production by T-cells and natural killer cells" [MESH:D12.644.276.374.465.512]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0008827 abnormal thymus cell ratio "deviation from the standard ratios of thymocyte subpopulations compared to control samples" [MGI:mberry "Melissa Berry, Genetics Resources Curator"]
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Allelic Composition: Il15tm1Imx/Il15tm1Imx
Genetic Background: C57BL/6NTac-Il15tm1Imx/Tac

Allelic Composition: Il15tm1Imx/Il15tm1Imx,Itktm1Litt/Itktm1Litt
Genetic Background: involves: 129S4/SvJae * C57BL/6

 MP:0009338 increased splenocyte number "increase in the expected number of cells of the spleen" [MGI:csmith "Cynthia L. Smith, Mouse Genome Informatics Curator"]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

 MP:0009789 decreased susceptibility to bacterial infection induced morbidity/mortality "reduced likelihood that an organism will display the expected moribund state caused by a bacterial invasion or from components of or toxins produced by bacteria" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0009791 increased susceptibility to viral infection induced morbidity/mortality "increased likelihood that an organism will display the expected moribund state caused by a viral invasion or from components of or toxins produced by a virus" [MGI:smb "Susan M. Bello, Mouse Genome Informatics Curator"]
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Allelic Composition: Ptger2tm1Sna/Ptger2tm1Sna
Genetic Background: involves: 129P2/OlaHsd * C57BL/6

 MP:0020519 renal glomerular immunoglobulin deposits "any anomalous accumulation of immunoglobulins in the renal glomerulus" [PMID:12764198, PMID:17685926]
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Allelic Composition: Cd8atm1Mak/Cd8atm1Mak,Il15tm1Imx/Il15tm1Imx,X/Yaa
Genetic Background: BXSB.Cg-Cd8atm1Mak Il15tm1Imx/Dcr

  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
 ENSMUSG00000059923 Grb2 / Q60631 / Growth factor receptor-bound protein 2 / P62993*  / complex
 ENSMUSG00000031304 Il2rg / P34902 / Cytokine receptor common subunit gamma / P31785* / AL590764.2* / interleukin 2 receptor subunit gamma*  / complex
 ENSMUSG00000042626 Shc1 / P98083 / SHC-transforming protein 1 / P29353* / SHC adaptor protein 1*  / complex
 ENSMUSG00000068227 Il2rb / P16297 / Interleukin-2 receptor subunit beta / P14784*  / complex
 ENSMUSG00000031712 Il15 / P48346 / Interleukin-15 / P40933*  / complex
 ENSMUSG00000031805 Jak3 / Janus kinase 3 / P52333*  / complex
 ENSMUSG00000028530 Jak1 / Janus kinase 1 / P23458*  / complex
 ENSMUSG00000023206 Il15ra / Q60819 / Interleukin-15 receptor subunit alpha Soluble interleukin-15 receptor subunit alpha / Q13261* / interleukin 15 receptor subunit alpha*  / complex / reaction






 

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