ENSMUSG00000035109


Mus musculus

Features
Gene ID: ENSMUSG00000035109
  
Biological name :Shc4
  
Synonyms : Q6S5L9 / Shc4 / SHC (Src homology 2 domain containing) family, member 4
  
Possible biological names infered from orthology : Q6S5L8 / SHC adaptor protein 4
  
Species: Mus musculus
  
Chr. number: 2
Strand: -1
Band: F1
Gene start: 125627447
Gene end: 125724148
  
Corresponding Affymetrix probe sets: 10487139 (MoGene1.0st)   1457118_at (Mouse Genome 430 2.0 Array)   
  
Cross references: Ensembl peptide - ENSMUSP00000043146
Ensembl peptide - ENSMUSP00000106103
Ensembl peptide - ENSMUSP00000106106
NCBI entrez gene - 271849     See in Manteia.
MGI - MGI:2655364
RefSeq - XM_006499657
RefSeq - NM_199022
RefSeq - XM_006499655
RefSeq - XM_006499656
RefSeq Peptide - NP_950187
swissprot - A2AUN0
swissprot - Q6S5L9
Ensembl - ENSMUSG00000035109
  
See expression report in BioGPS
See gene description in Wikigenes
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005011Gallus gallus
 SHC4ENSG00000185634Homo sapiens


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
Shc1 / P98083 / SHC-transforming protein 1 / P29353* / SHC adaptor protein 1*ENSMUSG0000004262643
Shc2 / Q8BMC3 / SHC (Src homology 2 domain containing) transforming protein 2 / P98077* / SHC adaptor protein 2*ENSMUSG0000002031237
Shc3 / Q61120 / src homology 2 domain-containing transforming protein C3 / Q92529* / SHC adaptor protein 3*ENSMUSG0000002144835


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR006019  Phosphotyrosine interaction domain, Shc-like
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR029596  SHC-transforming protein 4
 IPR035676  SH2 adaptor protein C, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IMP
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IMP
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0048863 stem cell differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019904 protein domain specific binding IPI
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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