ENSG00000185634


Homo sapiens

Features
Gene ID: ENSG00000185634
  
Biological name :SHC4
  
Synonyms : Q6S5L8 / SHC4 / SHC adaptor protein 4
  
Possible biological names infered from orthology :
  
Species: Homo sapiens
  
Chr. number: 15
Strand: -1
Band: q21.1
Gene start: 48823735
Gene end: 48963444
  
Corresponding Affymetrix probe sets: 230538_at (Human Genome U133 Plus 2.0 Array)   235238_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: Ensembl peptide - ENSP00000379786
Ensembl peptide - ENSP00000453344
Ensembl peptide - ENSP00000453397
Ensembl peptide - ENSP00000329668
Ensembl peptide - ENSP00000443300
NCBI entrez gene - 399694     See in Manteia.
OMIM - 617372
RefSeq - XM_005254375
RefSeq - NM_203349
RefSeq Peptide - NP_976224
swissprot - H0YLZ2
swissprot - F5H5M1
swissprot - Q6S5L8
swissprot - H0YLU6
Ensembl - ENSG00000185634
  
See expression report in BioGPS
See gene description in Wikigenes
See gene description in GeneCards
See co-cited genes in PubMed


Ortholog prediction (from Ensembl)
Ortholog nameID Species
 ENSGALG00000005011Gallus gallus
 Shc4ENSMUSG00000035109Mus musculus


Paralog prediction (from Ensembl)
Paralog nameIDSimilarity(%)
SHC1 / P29353 / SHC adaptor protein 1ENSG0000016069145
SHC3 / Q92529 / SHC adaptor protein 3ENSG0000014808241
SHC2 / P98077 / SHC adaptor protein 2ENSG0000012994637


Protein motifs (from Interpro)
Interpro ID Name
 IPR000980  SH2 domain
 IPR006019  Phosphotyrosine interaction domain, Shc-like
 IPR006020  PTB/PI domain
 IPR011993  PH-like domain superfamily
 IPR029596  SHC-transforming protein 4
 IPR035676  SH2 adaptor protein C, SH2 domain
 IPR036860  SH2 domain superfamily


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0006915 apoptotic process IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IBA
 biological_processGO:0008284 positive regulation of cell proliferation IEA
 biological_processGO:0010468 regulation of gene expression IEA
 biological_processGO:0035556 intracellular signal transduction IEA
 biological_processGO:0048863 stem cell differentiation IEA
 cellular_componentGO:0005622 intracellular IEA
 cellular_componentGO:0005886 plasma membrane IBA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0045202 synapse IEA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 molecular_functionGO:0005515 protein binding IEA
 molecular_functionGO:0019904 protein domain specific binding IEA
 molecular_functionGO:0030971 receptor tyrosine kinase binding IEA


Pathways (from Reactome)
Pathway description
No match


Phenotype (from MGI, Zfin or HPO)
IDPhenotypeDefinition Genetic BG
No match
  


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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