16590


Mus musculus (NCBI)

Features
Gene ID: 16590
  
Biological name :
  
Synonyms : Bs|CD117|Fdc|Gsfsco1|Gsfsco5|Gsfsow3|SCO1|SCO5|SOW3|Ssm|Tr-kit|W|c-KIT / Kit / KIT proto-oncogene receptor tyrosine kinase
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1415900_a_at (Mouse Genome 430 2.0 Array)   1452514_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 1039770614
RefSeq - 170650719
RefSeq - 170650721
RefSeq - NC_000071.6
RefSeq - NP_001116205.1
RefSeq - NP_066922.2
RefSeq - XP_017176176.1
RefSeq - NM_001122733.1
RefSeq - NM_021099.3
RefSeq - XM_017320687.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000005672 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000187 activation of MAPK activity ISO
 biological_processGO:0001541 ovarian follicle development IMP
 biological_processGO:0002318 myeloid progenitor cell differentiation IGI
 biological_processGO:0002320 lymphoid progenitor cell differentiation IGI
 biological_processGO:0002327 immature B cell differentiation IMP
 biological_processGO:0002371 dendritic cell cytokine production IMP
 biological_processGO:0002551 mast cell chemotaxis ISO
 biological_processGO:0002573 myeloid leukocyte differentiation IMP
 biological_processGO:0006468 protein phosphorylation IDA
 biological_processGO:0006687 glycosphingolipid metabolic process IMP
 biological_processGO:0006935 chemotaxis TAS
 biological_processGO:0006954 inflammatory response IMP
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0007281 germ cell development TAS
 biological_processGO:0007283 spermatogenesis ISO
 biological_processGO:0007286 spermatid development IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISO
 biological_processGO:0008354 germ cell migration ISO
 biological_processGO:0008360 regulation of cell shape IDA
 biological_processGO:0008542 visual learning ISO
 biological_processGO:0009314 response to radiation IMP
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0010628 positive regulation of gene expression IMP
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0018108 peptidyl-tyrosine phosphorylation ISO
 biological_processGO:0019221 cytokine-mediated signaling pathway ISO
 biological_processGO:0030032 lamellipodium assembly IDA
 biological_processGO:0030097 hemopoiesis IMP
 biological_processGO:0030154 cell differentiation TAS
 biological_processGO:0030217 T cell differentiation IMP
 biological_processGO:0030218 erythrocyte differentiation TAS
 biological_processGO:0030318 melanocyte differentiation IMP
 biological_processGO:0030335 positive regulation of cell migration ISO
 biological_processGO:0031274 positive regulation of pseudopodium assembly ISO
 biological_processGO:0031532 actin cytoskeleton reorganization ISO
 biological_processGO:0032762 mast cell cytokine production ISO
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035019 somatic stem cell population maintenance ISO
 biological_processGO:0035162 embryonic hemopoiesis IMP
 biological_processGO:0035234 ectopic germ cell programmed cell death IGI
 biological_processGO:0035556 intracellular signal transduction IDA
 biological_processGO:0035701 hematopoietic stem cell migration IMP
 biological_processGO:0035855 megakaryocyte development IMP
 biological_processGO:0038093 Fc receptor signaling pathway ISO
 biological_processGO:0038109 Kit signaling pathway ISO
 biological_processGO:0038162 erythropoietin-mediated signaling pathway IMP
 biological_processGO:0042531 positive regulation of tyrosine phosphorylation of STAT protein ISO
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043069 negative regulation of programmed cell death IMP
 biological_processGO:0043303 mast cell degranulation ISO
 biological_processGO:0043406 positive regulation of MAP kinase activity IGI
 biological_processGO:0043410 positive regulation of MAPK cascade ISO
 biological_processGO:0043473 pigmentation IMP
 biological_processGO:0045747 positive regulation of Notch signaling pathway ISO
 biological_processGO:0046427 positive regulation of JAK-STAT cascade ISO
 biological_processGO:0046777 protein autophosphorylation TAS
 biological_processGO:0048066 developmental pigmentation IMP
 biological_processGO:0048070 regulation of developmental pigmentation IMP
 biological_processGO:0048103 somatic stem cell division ISO
 biological_processGO:0048170 positive regulation of long-term neuronal synaptic plasticity ISO
 biological_processGO:0048565 digestive tract development IMP
 biological_processGO:0048863 stem cell differentiation IMP
 biological_processGO:0050673 epithelial cell proliferation ISO
 biological_processGO:0050910 detection of mechanical stimulus involved in sensory perception of sound IMP
 biological_processGO:0051091 positive regulation of DNA-binding transcription factor activity ISO
 biological_processGO:0060326 cell chemotaxis ISO
 biological_processGO:0060374 mast cell differentiation IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0097067 cellular response to thyroid hormone stimulus IDA
 biological_processGO:0097324 melanocyte migration IMP
 biological_processGO:0097326 melanocyte adhesion IDA
 biological_processGO:0120072 positive regulation of pyloric antrum smooth muscle contraction ISO
 biological_processGO:1904251 regulation of bile acid metabolic process ISO
 biological_processGO:1904343 positive regulation of colon smooth muscle contraction ISO
 biological_processGO:1904349 positive regulation of small intestine smooth muscle contraction ISO
 biological_processGO:1905065 positive regulation of vascular smooth muscle cell differentiation ISO
 cellular_componentGO:0001669 acrosomal vesicle ISO
 cellular_componentGO:0005615 extracellular space ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0005911 cell-cell junction IDA
 cellular_componentGO:0009897 external side of plasma membrane ISO
 cellular_componentGO:0009898 cytoplasmic side of plasma membrane ISO
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0002020 protease binding IPI
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity ISO
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity ISO
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0005020 stem cell factor receptor activity IDA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0019955 cytokine binding ISO
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0046872 metal ion binding IEA


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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