14255


Mus musculus (NCBI)

Features
Gene ID: 14255
  
Biological name :
  
Synonyms : B230315G04|CD135|Flk-2|Flk2|Flt-3|Ly72|wmfl / Flt3 / FMS-like tyrosine kinase 3
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1419538_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - XP_006504868.1
RefSeq - 568938955
RefSeq - 568938957
RefSeq - NC_000071.6
RefSeq - NP_034359.2
RefSeq - XP_006504867.1
RefSeq - 122937353
RefSeq - NM_010229.2
RefSeq - XM_006504805.3
RefSeq - XM_006504804.3
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000042817 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0001776 leukocyte homeostasis IMP
 biological_processGO:0001934 positive regulation of protein phosphorylation IGI
 biological_processGO:0002318 myeloid progenitor cell differentiation IMP
 biological_processGO:0002320 lymphoid progenitor cell differentiation IGI
 biological_processGO:0002328 pro-B cell differentiation IMP
 biological_processGO:0002572 pro-T cell differentiation IMP
 biological_processGO:0006468 protein phosphorylation IEA
 biological_processGO:0007169 transmembrane receptor protein tyrosine kinase signaling pathway IEA
 biological_processGO:0007275 multicellular organism development IBA
 biological_processGO:0008285 negative regulation of cell proliferation IMP
 biological_processGO:0009791 post-embryonic development IGI
 biological_processGO:0009968 negative regulation of signal transduction IBA
 biological_processGO:0016310 phosphorylation IEA
 biological_processGO:0019221 cytokine-mediated signaling pathway IMP
 biological_processGO:0019882 antigen processing and presentation IMP
 biological_processGO:0030097 hemopoiesis ISO
 biological_processGO:0030098 lymphocyte differentiation IDA
 biological_processGO:0030154 cell differentiation IEA
 biological_processGO:0030183 B cell differentiation IMP
 biological_processGO:0032715 negative regulation of interleukin-6 production IMP
 biological_processGO:0032720 negative regulation of tumor necrosis factor production IMP
 biological_processGO:0032727 positive regulation of interferon-alpha production IMP
 biological_processGO:0032729 positive regulation of interferon-gamma production IMP
 biological_processGO:0032735 positive regulation of interleukin-12 production IMP
 biological_processGO:0033674 positive regulation of kinase activity IBA
 biological_processGO:0035726 common myeloid progenitor cell proliferation IMP
 biological_processGO:0036145 dendritic cell homeostasis IMP
 biological_processGO:0040018 positive regulation of multicellular organism growth IMP
 biological_processGO:0043066 negative regulation of apoptotic process IBA
 biological_processGO:0043410 positive regulation of MAPK cascade IBA
 biological_processGO:0045578 negative regulation of B cell differentiation IDA
 biological_processGO:0046651 lymphocyte proliferation IMP
 biological_processGO:0046777 protein autophosphorylation IDA
 biological_processGO:0048535 lymph node development IMP
 biological_processGO:0048536 spleen development IGI
 biological_processGO:0048873 homeostasis of number of cells within a tissue IMP
 biological_processGO:0070374 positive regulation of ERK1 and ERK2 cascade IBA
 biological_processGO:0071345 cellular response to cytokine stimulus IMP
 biological_processGO:0097028 dendritic cell differentiation IMP
 biological_processGO:0098586 cellular response to virus IMP
 biological_processGO:1902715 positive regulation of interferon-gamma secretion IMP
 biological_processGO:1902741 positive regulation of interferon-alpha secretion IMP
 biological_processGO:2001184 positive regulation of interleukin-12 secretion IMP
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005783 endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005886 plasma membrane ISO
 cellular_componentGO:0005887 integral component of plasma membrane IBA
 cellular_componentGO:0009897 external side of plasma membrane IDA
 cellular_componentGO:0009986 cell surface IDA
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0016021 integral component of membrane IEA
 cellular_componentGO:0032991 protein-containing complex ISO
 cellular_componentGO:0043235 receptor complex IBA
 molecular_functionGO:0000166 nucleotide binding IEA
 molecular_functionGO:0004672 protein kinase activity IEA
 molecular_functionGO:0004709 MAP kinase kinase kinase activity IBA
 molecular_functionGO:0004713 protein tyrosine kinase activity IDA
 molecular_functionGO:0004714 transmembrane receptor protein tyrosine kinase activity IEA
 molecular_functionGO:0004888 transmembrane signaling receptor activity IBA
 molecular_functionGO:0004896 cytokine receptor activity IMP
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0005524 ATP binding IEA
 molecular_functionGO:0016301 kinase activity IEA
 molecular_functionGO:0016740 transferase activity IEA
 molecular_functionGO:0019838 growth factor binding IBA
 molecular_functionGO:0031434 mitogen-activated protein kinase kinase binding IBA
 molecular_functionGO:0031625 ubiquitin protein ligase binding IPI
 molecular_functionGO:0035259 glucocorticoid receptor binding ISO
 molecular_functionGO:0043548 phosphatidylinositol 3-kinase binding IDA
 molecular_functionGO:0043621 protein self-association ISO
 molecular_functionGO:0044877 protein-containing complex binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

0 s.

 
External programs and data are copyrighted by and are the property of their respective authors.
The Manteia system, data and analyses are provided "as is" with no warranties, expressed or implied as to capabilities or accuracy. User assumes the entire risk as to the results and performance of the software, data and documentation


                   

© Olivier Tassy / Olivier Pourquie 2007-2025
contact: otassy@igbmc.fr