14265


Mus musculus (NCBI)

Features
Gene ID: 14265
  
Biological name :
  
Synonyms : Fmr1 / FMRP|Fmr-1 / fragile X mental retardation 1
  
Possible biological names infered from orthology :
  
Species: Mus musculus (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 1423369_at (Mouse Genome 430 2.0 Array)   1426086_a_at (Mouse Genome 430 2.0 Array)   1452550_a_at (Mouse Genome 430 2.0 Array)   
  
Cross references: RefSeq - 51036613
RefSeq - 569009685
RefSeq - 569009687
RefSeq - 569009691
RefSeq - 569009693
RefSeq - 594150368
RefSeq - NC_000086.7
RefSeq - NP_001277353.1
RefSeq - NP_032057.2
RefSeq - XP_006527873.1
RefSeq - XP_006527874.1
RefSeq - XP_006527876.1
RefSeq - XP_006527877.1
RefSeq - XM_006527813.1
RefSeq - NM_001290424.1
RefSeq - NM_008031.3
RefSeq - XM_006527814.1
RefSeq - XR_001782738.1
RefSeq - XM_006527810.1
RefSeq - XM_006527811.1
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSMUSG00000000838 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000381 regulation of alternative mRNA splicing, via spliceosome ISO
 biological_processGO:0001934 positive regulation of protein phosphorylation ISO
 biological_processGO:0002091 negative regulation of receptor internalization ISO
 biological_processGO:0002092 positive regulation of receptor internalization ISO
 biological_processGO:0006397 mRNA processing IEA
 biological_processGO:0006417 regulation of translation IEA
 biological_processGO:0006974 cellular response to DNA damage stimulus ISO
 biological_processGO:0007215 glutamate receptor signaling pathway ISO
 biological_processGO:0007399 nervous system development IEA
 biological_processGO:0007417 central nervous system development IMP
 biological_processGO:0008089 anterograde axonal transport IMP
 biological_processGO:0008380 RNA splicing IEA
 biological_processGO:0010628 positive regulation of gene expression ISO
 biological_processGO:0010629 negative regulation of gene expression ISO
 biological_processGO:0010955 negative regulation of protein processing ISO
 biological_processGO:0017148 negative regulation of translation IDA
 biological_processGO:0031047 gene silencing by RNA IEA
 biological_processGO:0033129 positive regulation of histone phosphorylation ISO
 biological_processGO:0034644 cellular response to UV IDA
 biological_processGO:0043488 regulation of mRNA stability IMP
 biological_processGO:0043524 negative regulation of neuron apoptotic process ISO
 biological_processGO:0044830 modulation by host of viral RNA genome replication ISO
 biological_processGO:0045665 negative regulation of neuron differentiation ISO
 biological_processGO:0045727 positive regulation of translation ISO
 biological_processGO:0045947 negative regulation of translational initiation IDA
 biological_processGO:0046928 regulation of neurotransmitter secretion ISO
 biological_processGO:0048666 neuron development IBA
 biological_processGO:0048814 regulation of dendrite morphogenesis IBA
 biological_processGO:0051028 mRNA transport IDA
 biological_processGO:0051489 regulation of filopodium assembly ISO
 biological_processGO:0051491 positive regulation of filopodium assembly IDA
 biological_processGO:0060964 regulation of gene silencing by miRNA ISO
 biological_processGO:0060996 dendritic spine development IGI
 biological_processGO:0060998 regulation of dendritic spine development ISO
 biological_processGO:0060999 positive regulation of dendritic spine development IDA
 biological_processGO:0072711 cellular response to hydroxyurea IDA
 biological_processGO:0098586 cellular response to virus ISO
 biological_processGO:0098908 regulation of neuronal action potential ISO
 biological_processGO:0099578 regulation of translation at postsynapse, modulating synaptic transmission IMP
 biological_processGO:1900453 negative regulation of long term synaptic depression IMP
 biological_processGO:1901254 positive regulation of intracellular transport of viral material ISO
 biological_processGO:1901386 negative regulation of voltage-gated calcium channel activity ISO
 biological_processGO:1901800 positive regulation of proteasomal protein catabolic process IDA
 biological_processGO:1902373 negative regulation of mRNA catabolic process ISO
 biological_processGO:1902416 positive regulation of mRNA binding ISO
 biological_processGO:1905244 regulation of modification of synaptic structure IMP
 biological_processGO:2000301 negative regulation of synaptic vesicle exocytosis ISO
 biological_processGO:2000637 positive regulation of gene silencing by miRNA ISO
 biological_processGO:2000766 negative regulation of cytoplasmic translation IDA
 biological_processGO:2001022 positive regulation of response to DNA damage stimulus ISO
 cellular_componentGO:0000775 chromosome, centromeric region IEA
 cellular_componentGO:0005634 nucleus ISO
 cellular_componentGO:0005654 nucleoplasm ISO
 cellular_componentGO:0005694 chromosome IDA
 cellular_componentGO:0005730 nucleolus ISO
 cellular_componentGO:0005737 cytoplasm ISO
 cellular_componentGO:0005790 smooth endoplasmic reticulum ISO
 cellular_componentGO:0005791 rough endoplasmic reticulum ISO
 cellular_componentGO:0005829 cytosol ISO
 cellular_componentGO:0005844 polysome ISO
 cellular_componentGO:0005845 mRNA cap binding complex IDA
 cellular_componentGO:0005874 microtubule ISO
 cellular_componentGO:0005886 plasma membrane IEA
 cellular_componentGO:0010369 chromocenter IDA
 cellular_componentGO:0010494 cytoplasmic stress granule ISO
 cellular_componentGO:0014069 postsynaptic density ISO
 cellular_componentGO:0015030 Cajal body ISO
 cellular_componentGO:0016020 membrane IEA
 cellular_componentGO:0019034 viral replication complex ISO
 cellular_componentGO:0019897 extrinsic component of plasma membrane IDA
 cellular_componentGO:0030054 cell junction IEA
 cellular_componentGO:0030424 axon ISO
 cellular_componentGO:0030425 dendrite ISO
 cellular_componentGO:0030426 growth cone ISO
 cellular_componentGO:0032433 filopodium tip IDA
 cellular_componentGO:0032797 SMN complex ISO
 cellular_componentGO:0035770 ribonucleoprotein granule IDA
 cellular_componentGO:0036464 cytoplasmic ribonucleoprotein granule ISO
 cellular_componentGO:0042995 cell projection ISO
 cellular_componentGO:0043005 neuron projection ISO
 cellular_componentGO:0043025 neuronal cell body ISO
 cellular_componentGO:0043195 terminal bouton ISO
 cellular_componentGO:0043197 dendritic spine ISO
 cellular_componentGO:0043204 perikaryon ISO
 cellular_componentGO:0043679 axon terminus ISO
 cellular_componentGO:0044295 axonal growth cone IBA
 cellular_componentGO:0044297 cell body ISO
 cellular_componentGO:0044326 dendritic spine neck ISO
 cellular_componentGO:0044327 dendritic spine head ISO
 cellular_componentGO:0045202 synapse IDA
 cellular_componentGO:0045211 postsynaptic membrane IEA
 cellular_componentGO:0048471 perinuclear region of cytoplasm ISO
 cellular_componentGO:0071598 neuronal ribonucleoprotein granule ISO
 cellular_componentGO:0097386 glial cell projection ISO
 cellular_componentGO:0097444 spine apparatus ISO
 cellular_componentGO:0098793 presynapse IDA
 cellular_componentGO:0098794 postsynapse IDA
 cellular_componentGO:1902737 dendritic filopodium ISO
 cellular_componentGO:1990124 messenger ribonucleoprotein complex ISO
 cellular_componentGO:1990635 proximal dendrite ISO
 cellular_componentGO:1990812 growth cone filopodium IDA
 cellular_componentGO:1990904 ribonucleoprotein complex ISO
 molecular_functionGO:0000340 RNA 7-methylguanosine cap binding ISO
 molecular_functionGO:0002151 G-quadruplex RNA binding ISO
 molecular_functionGO:0003676 nucleic acid binding IEA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003723 RNA binding ISO
 molecular_functionGO:0003729 mRNA binding ISO
 molecular_functionGO:0003730 mRNA 3"-UTR binding ISO
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008017 microtubule binding IDA
 molecular_functionGO:0008266 poly(U) RNA binding ISO
 molecular_functionGO:0019901 protein kinase binding ISO
 molecular_functionGO:0019903 protein phosphatase binding ISO
 molecular_functionGO:0019904 protein domain specific binding ISO
 molecular_functionGO:0030371 translation repressor activity ISO
 molecular_functionGO:0031369 translation initiation factor binding ISO
 molecular_functionGO:0033592 RNA strand annealing activity ISO
 molecular_functionGO:0034046 poly(G) binding ISO
 molecular_functionGO:0035064 methylated histone binding ISO
 molecular_functionGO:0035197 siRNA binding ISO
 molecular_functionGO:0035198 miRNA binding ISO
 molecular_functionGO:0035613 RNA stem-loop binding ISO
 molecular_functionGO:0042802 identical protein binding ISO
 molecular_functionGO:0042803 protein homodimerization activity ISO
 molecular_functionGO:0043022 ribosome binding ISO
 molecular_functionGO:0044325 ion channel binding ISO
 molecular_functionGO:0045182 translation regulator activity IBA
 molecular_functionGO:0046982 protein heterodimerization activity ISO
 molecular_functionGO:0048027 mRNA 5"-UTR binding ISO
 molecular_functionGO:0070840 dynein complex binding IDA
 molecular_functionGO:1990825 sequence-specific mRNA binding ISO


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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