1482


Homo sapiens (NCBI)

Features
Gene ID: 1482
  
Biological name :
  
Synonyms : CHNG5|CSX|CSX1|HLHS2|NKX2.5|NKX2E|NKX4-1|VSD3 / NK2 homeobox 5 / NKX2-5
  
Possible biological names infered from orthology :
  
Species: Homo sapiens (NCBI)
  
Chr. number:
Strand:
Band:
Gene start:
Gene end:
  
Corresponding Affymetrix probe sets: 206578_at (Human Genome U133 Plus 2.0 Array)   
  
Cross references: RefSeq - 1034643686
RefSeq - 260898750
RefSeq - 260898752
RefSeq - 4758090
RefSeq - NC_000005.10
RefSeq - NG_013340.1
RefSeq - NP_001159647.1
RefSeq - NP_001159648.1
RefSeq - NP_004378.1
RefSeq - XP_016864560.1
RefSeq - NM_001166175.1
RefSeq - NM_001166176.1
RefSeq - NM_004387.3
RefSeq - XM_017009071.2
  
See co-cited genes in PubMed
Warning: Please see the Ensembl gene model ENSG00000183072 to get all the annotations available for this gene.


Gene Ontology (GO)
TypeGO IDTermEv.Code
 biological_processGO:0000122 negative regulation of transcription by RNA polymerase II ISS
 biological_processGO:0001570 vasculogenesis ISS
 biological_processGO:0001947 heart looping ISS
 biological_processGO:0003007 heart morphogenesis ISS
 biological_processGO:0003148 outflow tract septum morphogenesis IMP
 biological_processGO:0003161 cardiac conduction system development IMP
 biological_processGO:0003166 bundle of His development IEA
 biological_processGO:0003168 Purkinje myocyte differentiation IEA
 biological_processGO:0003211 cardiac ventricle formation IEA
 biological_processGO:0003221 right ventricular cardiac muscle tissue morphogenesis IMP
 biological_processGO:0003222 ventricular trabecula myocardium morphogenesis IEA
 biological_processGO:0003278 apoptotic process involved in heart morphogenesis IEA
 biological_processGO:0003285 septum secundum development IMP
 biological_processGO:0003342 proepicardium development IEA
 biological_processGO:0003350 pulmonary myocardium development IEA
 biological_processGO:0006366 transcription by RNA polymerase II IEA
 biological_processGO:0007512 adult heart development IMP
 biological_processGO:0008284 positive regulation of cell proliferation ISS
 biological_processGO:0010667 negative regulation of cardiac muscle cell apoptotic process IMP
 biological_processGO:0010735 positive regulation of transcription via serum response element binding ISS
 biological_processGO:0010765 positive regulation of sodium ion transport ISS
 biological_processGO:0010832 negative regulation of myotube differentiation IMP
 biological_processGO:0030097 hemopoiesis ISS
 biological_processGO:0030154 cell differentiation ISS
 biological_processGO:0030509 BMP signaling pathway IEA
 biological_processGO:0030878 thyroid gland development IMP
 biological_processGO:0035050 embryonic heart tube development ISS
 biological_processGO:0043066 negative regulation of apoptotic process ISS
 biological_processGO:0045214 sarcomere organization IEA
 biological_processGO:0045666 positive regulation of neuron differentiation IMP
 biological_processGO:0045823 positive regulation of heart contraction ISS
 biological_processGO:0045892 negative regulation of transcription, DNA-templated ISS
 biological_processGO:0045893 positive regulation of transcription, DNA-templated ISS
 biological_processGO:0045944 positive regulation of transcription by RNA polymerase II ISS
 biological_processGO:0048536 spleen development ISS
 biological_processGO:0051891 positive regulation of cardioblast differentiation ISS
 biological_processGO:0055005 ventricular cardiac myofibril assembly IEA
 biological_processGO:0055007 cardiac muscle cell differentiation ISS
 biological_processGO:0055008 cardiac muscle tissue morphogenesis IMP
 biological_processGO:0055014 atrial cardiac muscle cell development ISS
 biological_processGO:0055015 ventricular cardiac muscle cell development ISS
 biological_processGO:0055117 regulation of cardiac muscle contraction ISS
 biological_processGO:0060037 pharyngeal system development ISS
 biological_processGO:0060038 cardiac muscle cell proliferation IEA
 biological_processGO:0060043 regulation of cardiac muscle cell proliferation IEA
 biological_processGO:0060048 cardiac muscle contraction IEA
 biological_processGO:0060070 canonical Wnt signaling pathway IEA
 biological_processGO:0060261 positive regulation of transcription initiation from RNA polymerase II promoter ISS
 biological_processGO:0060347 heart trabecula formation IEA
 biological_processGO:0060412 ventricular septum morphogenesis IMP
 biological_processGO:0060413 atrial septum morphogenesis IMP
 biological_processGO:0060928 atrioventricular node cell development IEA
 biological_processGO:0060929 atrioventricular node cell fate commitment IEA
 biological_processGO:0060971 embryonic heart tube left/right pattern formation IEA
 biological_processGO:0090090 negative regulation of canonical Wnt signaling pathway ISS
 biological_processGO:1903779 regulation of cardiac conduction ISS
 cellular_componentGO:0005634 nucleus IDA
 cellular_componentGO:0005667 transcription factor complex IC
 cellular_componentGO:0005737 cytoplasm IEA
 cellular_componentGO:0032991 protein-containing complex IDA
 cellular_componentGO:0032993 protein-DNA complex IDA
 cellular_componentGO:0090575 RNA polymerase II transcription factor complex IDA
 molecular_functionGO:0000978 RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0000981 RNA polymerase II transcription factor activity, sequence-specific DNA binding NAS
 molecular_functionGO:0001077 transcriptional activator activity, RNA polymerase II proximal promoter sequence-specific DNA binding IMP
 molecular_functionGO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding IEA
 molecular_functionGO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding IDA
 molecular_functionGO:0003677 DNA binding IDA
 molecular_functionGO:0003682 chromatin binding IDA
 molecular_functionGO:0003700 DNA-binding transcription factor activity IMP
 molecular_functionGO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding IEA
 molecular_functionGO:0003712 transcription coregulator activity IEA
 molecular_functionGO:0005515 protein binding IPI
 molecular_functionGO:0008134 transcription factor binding IPI
 molecular_functionGO:0010736 serum response element binding ISS
 molecular_functionGO:0042803 protein homodimerization activity IEA
 molecular_functionGO:0043565 sequence-specific DNA binding IDA
 molecular_functionGO:0044212 transcription regulatory region DNA binding IDA
 molecular_functionGO:0046982 protein heterodimerization activity ISS


Pathways (from Reactome)
Pathway description
No match


Interacting proteins (from Reactome)
Interactor ID Name Interaction type
No match






 

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